Dispersion of Single-Walled Carbon Nanotubes by Aromatic Cyclic Schiff Bases via Non-Covalent Interactions.

One of the challenging issues that hinders the application of single-walled carbon nanotubes (SWCNTs) is the poor solubility and the inevitable formation of bundles. Efforts still need to be made towards solving the problem. Herein, we report a non-covalent strategy to disperse aggregated SWCNTs by aromatic cyclic Schiff bases assisted by ultrasonic techniques. The aromatic cyclic Schiff base (OMM) was synthesized via Schiff base reactions, and the molecular structure was determined by ATR-FT-IR, solid-state 13C-NMR, and HRMS. Although the yielded product showed poor solubility in aqueous solution and organic solvents, it could interact with and disperse the aggregated SWCNTs in dimethyl formamide (DMF) under the condition of ultrasound. UV-vis-NIR, FL, Raman spectra, AFM, and TEM, along with computer simulations, provide evidence for the interactions between OMM molecules and SWCNTs and the dispersion thereof. The semiconductive (7,5), (8,6), (12,1), and (9,7)-SWCNTs expressed a preference for dissolution. The capability of dispersion is contributed by π-π, C-H·π, and lone pair (lp)·π interactions between OMM and SWCNTs based on the simulated results. The present non-covalent strategy could provide inspiration for preparing organic cyclic compounds as dispersants for SWCNTs and then facilitate their further utilization.

Amorphous Porous Organic Polymers Based on Schiff-Base Chemistry for Highly Efficient Iodine Capture.

Porous organic polymers (POPs) have been considered as prominent adsorbents for volatile iodine. So far, both crystalline and amorphous POPs have accomplished excellent iodine capture capability. Considering the difficulty and challenges in preparing perfect crystalline POPs, more explorations into developing versatile amorphous POPs are needed. Herein, amorphous POPs based on the Schiff-base reaction were designed and synthesized for volatile iodine removal. Four amorphous POPs products named as NDB-H, NDB-S, ADB-HS, and ADB-S obtained under different solvothermal conditions were investigated in terms of their morphologies, porosity, and their iodine enrichment performance in detail. It is noteworthy that excellent efficiency for removing iodine vapor was acquired for NDB-S (≈425 wt %), ADB-HS (≈345 wt %), and ADB-S (≈342 wt %). Remarkably, NDB-H exhibited an iodine capture capacity up to ≈443 wt %. Excellent reusability was obtained as well. Amorphous NDB-H has accomplished an extremely high iodine capture performance, illustrating the great chance to exploit versatile amorphous POPs for iodine enrichment and removal based on Schiff-base chemistry.

Intracoronary administration of tirofiban during percutaneous coronary intervention facilitates patients with acute coronary syndrome.

We assessed the efficacy and safety of tirofiban intracoronary versus intravenous administration during percutaneous coronary intervention for patients with acute coronary syndrome. The databases of PubMed, Web of Science, China National Knowledge Infrastructure, and WanFang Database were retrieved. A total of 437 articles were found, according to inclusive and exclusive criteria, 13 of which were finally included. Compared with subjects with intravenous administration, those with intracoronary administration were more likely to reach thrombolysis in myocardial infarction trial grade 3 flow (relative risk = 1.17, 95% confidence interval: 1.11-1.22), improve left ventricular ejection fraction (Standardized mean difference = 0.65, 95% confidence interval: 0.20-1.11). Intracoronary administration resulted in a reduced risk of major adverse cardiovascular events at 30-day follow-up (relative risk = 0.47, 95% confidence interval: 0.34-0.65). However, incidence of bleeding complications was not statistically significant between two groups (relative risk = 0.76, 95% confidence interval: 0.55-1.04). Intracoronary administration of tirofiban can be more effective in increasing coronary blood flow and microvascular perfusion, more effective in improving postoperative myocardial reperfusion, more significantly in reducing the incidence of adverse cardiovascular events at 30-day's follow-up and improving the prognosis after percutaneous coronary intervention without increasing the risk of bleeding.