[Malignant thymoma with symptoms of myasthenia gravis]. / Grasiczak zlosliwy z objawami nuzliwosci miesni.

The rare case of malignant tumor of thymus--Thymoma malignum was described. The initial diagnosis was difficult, because of the irregular symptoms of myasthenia gravis. The diagnostic difficulties, treatment and clinical features of this neoplasm were also discussed.

[Parakeratosis of larynx as a base of cancerogenesis]. / Parakeratoza krtani jako podloze do rozwoju raka.

Keratosis, parakeratosis and hyperkeratosis of the larynx and hyperkeratotic papilloma with the inflammation should be treated as clinical precancerous state. Parakeratosis and cellular dysplasia are histological features of cancerogenesis. The patient with extensive verrucous keratosis of the larynx (described in the article) has been observed for 7 years. Eventually, the developed verrucous carcinoma of the larynx.

[Clinical and anatomopathological course of cancer starting in the vocal cords. Results of treatment]. / Evolution clinique et anatomo-pathologique du cancer débutant des cordes vocales. Résultats du traitement.

Histological examination of serial sections from 127 cases of precancerous lesions and 86 cases of early cancer of the vocal cords was conducted. A histological precancerous state was observed: cellular dysplasia. Analysis of progression of cancer of the vocal cords showed 4 different varieties of carcinogenesis: one sudden, one progressive, one by proliferation and one by transformation. Functional conservative surgery of a glottic cancer had been performed in 76.7 p. cent of cases, and cobalt therapy applied in 23.3 p. cent. Recurrence rate was 6.1 p. cent after surgery and 30.0 p. cent after irradiation. Recovery occurred in 75.6 p. cent after surgery and 65.0 p. cent after irradiation. Precancerous lesions were treated by conservative operations and by microsurgery.