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1.
Ind Health ; 62(2): 79-89, 2024 Apr 03.
Artículo en Inglés | MEDLINE | ID: mdl-37574281

RESUMEN

Blue light emitted during arc welding is known to potentially cause photoretinopathy. To help prevent retinal injury, it is important to identify the hazards associated with various welding conditions. The present work conducted experiments involving gas metal arc welding of mild steel under various conditions, and measured the spectral radiance of the arcs. The effective radiance values, as used by the American Conference of Governmental Industrial Hygienists (ACGIH) to quantify exposure level of blue light, were subsequently calculated from the data. The resulting values were in the range of 5.0-118 W/cm2/sr, corresponding to hazardous levels according to ACGIH guidelines. The effective radiance was increased at higher welding currents and when pulsed currents were used rather than steady currents. The blue light hazard was also affected by the type of shielding gas employed. These data confirm that it is very hazardous to stare at arcs during gas metal arc welding of mild steel. As such, appropriate eye protection is necessary during arc welding, and directly staring at the arc should be avoided.


Asunto(s)
Contaminantes Ocupacionales del Aire , Exposición Profesional , Soldadura , Humanos , Acero , Soldadura/métodos , Gases , Exposición Profesional/análisis , Luz Azul , Rayos Ultravioleta
2.
Epilepsia Open ; 7(1): 85-97, 2022 03.
Artículo en Inglés | MEDLINE | ID: mdl-34773678

RESUMEN

OBJECTIVE: Among standard treatments for infantile spasms, adrenocorticotropic hormone (ACTH) is reported as the best treatment, but ACTH is ineffective in one-half of the patients. To establish precision medicine, we examined pharmacoresistance of focal epileptic spasms (ES), generalized ES, and generalized ES combined with focal seizures, diagnosed based on the revised seizure classification of ILAE in 2017. METHODS: We conducted a retrospective nationwide study in Japan on the long-term seizure outcome of ES. Long-term seizure outcome was evaluated by seizure-free rate, seizure-free period, and Kaplan-Meier curve. Seizure-free was defined as seizure control for longer than 2 months. RESULTS: From the medical history of 501 patients, 325 patients had generalized ES only (GES group) at the start of the first treatment, 125 patients had generalized ES after focal seizure onset (FS-GES group), seven patients had focal ES after focal seizure onset (FS-FES group), and 24 patients had generalized ES combined with focal seizures after focal seizure onset (FS-GES + FS group). Seizure-free period of ES (generalized ES and focal ES) [mean (95% confidence interval)] was 2.7 (0.0-5.4) months in GES group, 1.1 (0.1-2.2) months in FS-GES group, 1.0 (0.2-1.9) months in FS-GES + FS group, and 0.1 (-0.2-0.5) months in FS-FES group. Seizure-free rate, seizure-free period, and Kaplan-Meier curve of generalized ES were almost the same in GES group and FS-GES group, with characteristics of superior response to ACTH. Mean seizure-free period of generalized ES combined with focal seizures was significantly shorter in FS-GES + FS group than in GES group. Mean seizure-free period of focal ES in FS-FES group was extremely short with exceedingly early relapse. SIGNIFICANCE: Pharmacoresistance was different in generalized ES, focal ES, and generalized ES combined with focal seizures. ES with focal features or with focal seizures may have focal lesions, thus consider surgical options earlier in the course.


Asunto(s)
Espasmos Infantiles , Electroencefalografía , Humanos , Estudios Retrospectivos , Convulsiones/tratamiento farmacológico , Espasmo , Espasmos Infantiles/tratamiento farmacológico
3.
Ind Health ; 58(4): 325-334, 2020 Aug 07.
Artículo en Inglés | MEDLINE | ID: mdl-31932524

RESUMEN

This study measured the fume particle size distribution and fume generation rate during arc welding of cast iron and estimated the generation rate of respirable dust. In addition, the generation rate of particles with a diameter of 0.3 µm or less was estimated. In this experiment, three types of filler materials (mild steel wire, stainless steel wire, and mild steel covered electrodes) with main constituents of Fe or Fe-Cr-Ni, as proposed previously by the authors, were used. The welding methods were gas metal arc welding and shielded metal arc welding. The fumes measured in this research contained 73-91% respirable dust, and the fume generation rates were in the range of 1.96-12.2 mg/s. The results of this study were as follows: (i) the welding current affects the generation rate of respirable dust, and it is highly likely that the higher the fume generation rate, the more respirable dust is generated; (ii) the generation rates of respirable dust at low and high current were highest when mild steel covered electrodes and stainless steel wire was used, respectively; and (iii) the generation rate of particles with a diameter of 0.3 µm or less was highest when stainless steel wire is used.


Asunto(s)
Contaminantes Ocupacionales del Aire/análisis , Tamaño de la Partícula , Soldadura , Polvo/análisis , Hierro , Acero
4.
J Occup Health ; 62(1): e12091, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31794117

RESUMEN

OBJECTIVES: Ultraviolet radiation (UVR) emitted during arc welding frequently causes keratoconjunctivitis and skin erythema. The extent of the hazard of UVR varies depending on the welding process and conditions. Therefore, it is important to identify the levels of UVR present under different conditions. The purpose of this study was to investigate the degree of hazard of UVR emitted by the different types of arc welding of cast iron frequently used in industry. METHODS: In this study, we experimentally measured the UVR emitted during gas tungsten arc welding (GTAW), shielded metal arc welding (SMAW), and gas metal arc welding (GMAW) of cast iron. The degree of hazard of UVR was quantitatively evaluated in accordance with the guidelines of the American Conference of Governmental Industrial Hygienists. RESULTS: Effective irradiances measured in this study were in the range 0.045-2.2 mW/cm2 at a distance of 500 mm from the welding arc. The maximum allowable exposure times corresponding to these levels were only 1.4-67 s/day. CONCLUSIONS: UVR emitted during arc welding of cast iron has the following characteristics: (a) It is more hazardous at higher welding currents. (b) The magnitude of the hazard, which depends on the welding process, increases in the order of GMAW > SMAW > GTAW. (c) It is influenced by the filler material used; that is, the components contained in the filler material affect the hazard of UVR. The effect is Fe > Ni, Cr.


Asunto(s)
Exposición Profesional/análisis , Rayos Ultravioleta/efectos adversos , Soldadura , Humanos , Hierro
5.
Ann Work Expo Health ; 61(8): 965-974, 2017 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-29028248

RESUMEN

OBJECTIVES: The objective was to quantify the blue-light hazard from gas metal arc welding (GMAW) of aluminum alloys. The exposure level is expected to depend on the welding conditions. Therefore, it is important to identify the blue-light hazard under various welding conditions. METHODS: We experimentally conducted GMAW of aluminum alloys under various welding conditions and measured the spectral radiance of the arcs. The effective blue-light radiance, which the American Conference of Governmental Industrial Hygienists has defined to quantify the exposure level of blue light, was calculated from the measured spectral radiance. The maximum acceptable exposure duration per 10000 s for this effective blue-light radiance was calculated. RESULTS: The effective blue-light radiance measured in this study was in the range of 2.9-20.0 W cm-2·sr. The corresponding maximum acceptable exposure duration per 10000 s was only 5.0-34 s, so it is hazardous to view the welding arc. The effective blue-light radiance was higher at higher welding currents than at lower welding currents, when pulsed welding currents were used rather than steady welding currents, and when magnesium was included in the welding materials. CONCLUSIONS: It is very hazardous to view the arcs in GMAW of aluminum alloys. Welders and their helpers should use appropriate eye protection in arc-welding operations. They should also avoid direct light exposure when starting an arc-welding operation.


Asunto(s)
Aluminio , Incandescencia/efectos adversos , Exposición Profesional/análisis , Exposición a la Radiación/análisis , Soldadura/métodos , Aleaciones , Gases/efectos adversos , Humanos , Mediciones Luminiscentes , Modelos Estadísticos , Enfermedades Profesionales/prevención & control , Salud Laboral , Traumatismos por Radiación/prevención & control , Enfermedades de la Retina/prevención & control
6.
J Occup Health ; 58(5): 452-459, 2016 Sep 30.
Artículo en Inglés | MEDLINE | ID: mdl-27488036

RESUMEN

OBJECTIVES: Ultraviolet radiation (UVR) emitted during arc welding frequently causes keratoconjunctivitis and erythema in the workplace. The degree of hazard from UVR exposure depends on the welding method and conditions. Therefore, it is important to identify the UVR levels present under various conditions. METHODS: We experimentally evaluated the UVR levels emitted in gas metal arc welding (GMAW) of mild steel. We used both a pulsed welding current and a non-pulsed welding current. The shielding gases were 80% Ar + 20% CO2 and 100% CO2. The effective irradiance defined in the American Conference of Governmental Industrial Hygienists guidelines was used to quantify the UVR hazard. RESULTS: The effective irradiance measured in this study was in the range of 0.51-12.9 mW/cm2 at a distance of 500 mm from the arc. The maximum allowable exposure times at these levels are only 0.23-5.9 s/day. CONCLUSIONS: The following conclusions were made regarding the degree of hazard from UVR exposure during the GMAW of mild steel: (1) It is more hazardous at higher welding currents than at lower welding currents. (2) At higher welding currents, it is more hazardous when 80% Ar + 20% CO2 is used as a shielding gas than when 100% CO2 is used. (3) It is more hazardous for pulsed welding currents than for non-pulsed welding currents. (4) It appears to be very hazardous when metal transfer is the spray type. This study demonstrates that unprotected exposure to UVR emitted by the GMAW of mild steel is quite hazardous.


Asunto(s)
Contaminantes Ocupacionales del Aire/análisis , Gases/análisis , Exposición Profesional/análisis , Rayos Ultravioleta , Contaminantes Ocupacionales del Aire/efectos adversos , Monitoreo del Ambiente , Gases/efectos adversos , Gases/normas , Humanos , Exposición Profesional/efectos adversos , Exposición Profesional/normas , Salud Laboral , Medición de Riesgo , Acero , Rayos Ultravioleta/efectos adversos , Soldadura
7.
No To Hattatsu ; 40(4): 328-32, 2008 Jul.
Artículo en Japonés | MEDLINE | ID: mdl-18634420

RESUMEN

A normally developed 5-year-old boy with no history of convulsive disorder presented with a generalized tonic-clonic convulsion on the second day of oral theophylline therapy. Although the convulsive seizure was abolished by an intravenous bolus of diazepam, he did not regain consciousness. Emergency electroencephalography disclosed continuous irregular seizure activity, occurring predominantly over the right hemisphere, indicating a diagnosis of nonconvulsive status epilepticus (NCSE). The serum theophylline concentration was 19.7 microg/mL. Treatment with an initial intravenous bolus of midazolam (0.26 mg/kg) largely restricted seizure activity to the right hemisphere, with activity then diminishing to continuous right occipital spikes. An additional 0.24 mg/kg bolus followed by continuous infusion at a rate of 0.20 mg/kg/hr completely abolished electrical status. Our case suggests that theophylline treatment can provoke NCSE even after successful control of a brief convulsion by initial antiseizure treatment in some patients predisposed toward localization-related epilepsy. This possibility should be kept in mind in any child receiving theophylline who presents with sustained unconsciousness.


Asunto(s)
Estado Epiléptico/inducido químicamente , Teofilina/efectos adversos , Administración Oral , Preescolar , Humanos , Masculino , Teofilina/administración & dosificación
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