Profiling the Cytopathological Diagnosis of Enlarged Lymph Nodes on Fine Needle Aspiration Cytology.

BACKGROUND: This study aimed to assess the distribution of fine-needle-aspiration-cytology or biopsy findings through cytopathological patterns of lymph nodes aspirations in different age groups of the population visiting a tertiary level hospital in Kathmandu. METHODS: The retrospective study was conducted on the database of the 226 lymphadenopathy cases that underwent biopsy fine needle aspiration cytology from 1 January 2016 to 31 December 2019 at the Department of pathology of Helping Hand's Community Hospital, Kathmandu. A descriptive analysis was performed yielding proportions and counts for the quantitative variables. Chi-squared test was used to compare the proportions.  Point estimates and confidence intervals for measures of association were assessed with 95% confidence interval and p-value ?0.05 was considered statistically significant. RESULTS: The 20-40 years were the most common age group undergoing biopsy fone needle aspiration cytology procedures. Males recorded majority of cases (68%, 153 of 226). The highest incidence of Reactive lymphadenitis was obtained (50%, 113 of 226) and it was the most common findings in the age group of <20 and 40-60 years. The Cervical lymph node (86%) was the most common anatomical location followed by axillary lymph nodes (8%). Squamous cell carcinoma and Adenocarcinoma accounted for more than half (53%, 20 of 38) of all the diagnosed malignancy. The incidence of Non-Hodgkin lymphoma and Hodgkin lymphoma were 8% (n = 3 of 38) and 5% (n = 2 of 38) respectively. CONCLUSIONS: Lymph node enlargement is associated with a wide range of etiologies with Reactive lymphadenitis as the most common cause and cervical lymph node as the common site.

Incorporating social dimensions in hydrological and water quality modeling to evaluate the effectiveness of agricultural beneficial management practices in a Prairie River Basin.

There is growing interest to develop processes for creating user-informed watershed scale models of hydrology and water quality and to assist in decision-making for balanced policies for managing watersheds. Watershed models can be enhanced with the incorporation of social dimensions of watershed management as brought forward by participants such as the perspectives, values, and norms of people that depend on the land, water, and ecosystems for sustenance, economies, and overall wellbeing. In this work, we explore the value of combining both qualitative and quantitative methods and social science data to enhance salience and legitimacy of watershed models so that end-users are more engaged. We discuss pilot testing and engagement workshops for building and testing a systems dynamics model of the Qu'Appelle Valley to gather insights from local farmers and understand their perceptions of Beneficial Management Practices (BMPs). Mixed-method workshops with agricultural producers in the Qu'Appelle Watershed gathered feedback on the developing model and the incorporation of social determinants affecting decision-making. Analysis of focus groups and factor analysis of Q-sorts were used to identify the desired components of the model, and whether it supported farmers' understanding of the potential effects of BMPs on water quality. We explored farmers' engagement with models testing BMPs and the potential of incorporating their decision processes within the model itself. Finally, we discuss the reception of the process and the practicality of the approach in providing legitimate and credible decision support tools for a community of farmers.