[Clinical epidemiologic study of admissions for ankylosing spondilitis at the Clinic of Rheumatology and Medical Rehabilitation, Hospital of Rehabilitation Iasi, between 1990 and 2007]. / Cercetari clinico-epidemiologice asupra evolutiei internarilor pentru spondilita anchilozanta în Clinica de Reumatologie si Recuperare medicala, Spitalul de Recuperare Iasi, în perioada 1990-2007.

MATERIAL AND METHOD: A retro-prospective study was carried out on a sample of 678 patients suffering from ankylosing spondilitis (AS), admitted in the Clinic of Rheumatology, Rehabilitation Hospital, Iasi. RESULTS: The analysis highlighted that 86.8% were males, with a soft predominance of urban area (57.1%). Over 50% of the entire sample was exposed to risk factors from industrial area; 11.6% from agriculture; 10.5%--various categories of intellectuals, and 17.8% included domestic and socioeconomic activities, difficult to estimate. Analysis of temporal interval between onset and diagnosis establishment attested that it was been performed during the first year for 42.7%; next 2-9 years, for 40.1%, and in 17.5% of cases, 10 and over 21 years. CONCLUSION: Difficulties in early diagnosis achievement, in order to obtain optimal therapeutic results and, consequently, reduce the important impact on patient, family and society, placed AS among diseases with serious medical, social and economic involvements.

[Some observations on therapy efficacy in a sample of 111 patients suffering from ankylosing spondylarthritis, assisted in the Clinic of Rheumatology and Rehabilitation Iasi]. / Unele observatii asupra eficientei terapiei pe un lot de 111 bolnavi cu spondiloartrita anchilozanta asistati in Clinica de Reumatologie si Recuperare Medicala din Iasi.

UNLABELLED: The authors present the results of some evaluations on the efficiency of pharmacologic therapy for 111 pacients suffering from ankylosing spondylarthritis (AS). RESULTS: The pacients have been assisted for five years in a specialized hospital. 63.9% out of all were over 30 years old and 46.8% were workers in industry and agriculture. Regarding the frequency of usage, the therapy included the following medicine: movalis, salasopyrine, diclophenac, flamezin, aulin, tilcotil, almiral, and others. After the therapy, during the study period, cumulative, the condition of 62.2% of the pacients improved. The condition of 22.5% remained stationary, and 6.3% got worse.

[Multidisciplinary prospective epidemiological research regarding the prevalence of ankylosing spondilytis, comparatively in Romania and Iasi County, between 1990-2006]. / Cercetari epidemiologice, retroprospective, multi- disciplinare, asupra prevalentei cazurilor de spondilita anchilozanta, comparativ in România si judetul Iasi, in perioada 1990-2006.

UNLABELLED: During the period of study, the prevalence of ankylosing spondylitis (AS) cases values varied between 5.65% per hundred thousand in 1994 and 3.96 in 1999. RESULTS: Are close to those obtained in the national research in 1989 (5.29% hundred thousand) and 1997 (6.34% hundred thousand). The sample of 6894 cases registered a prevalence of 28.86% in the 35-44 age groups with a decreasing trend, and 0.07% in = 85 age group. Males' prevalence was of 84.08%, comparatively with females (15.91% from total cases). Difference between residence areas had not statistic significance. In Iasi County, AS prevalence had increased values in all 17 years of study period, greater and often double that those at national level, and also greater than every county from Moldavia and one from the Western Romania. Demographical structure, variations, and those occupational, ecological, economical, educational could explain this situation. CONCLUSION: Ankylosing spondylitis is included among the major problems in order to promote community health, taking into account its clinical epidemiological characteristics.