RESUMEN
In the examination of 64 patients with chronic obstructive bronchitis, some specificities of functioning of decompensation mechanisms in the glutathione antiradical system were established as were changes in morphofunctional and receptor properties of erythrocytes in chronic obstructive bronchitis. The patients were shown to have derived benefit from a combined treatment involving the use of the enzymic drug preparation Wobe-Mugos E which was found to make for improvement of rheological properties of erythrocytes, their capability of depositing and transporting catecholamines.
Asunto(s)
Bronquitis/tratamiento farmacológico , Catecolaminas/sangre , Quimotripsina , Eritrocitos/metabolismo , Glutatión/sangre , Extractos Pancreáticos/uso terapéutico , Papaína/uso terapéutico , Extractos del Timo/uso terapéutico , Tripsina , Adulto , Bronquitis/sangre , Bronquitis/enzimología , Enfermedad Crónica , Combinación de Medicamentos , Eritrocitos/química , Radicales Libres/sangre , Humanos , Malondialdehído/sangre , Persona de Mediana Edad , ReologíaRESUMEN
Properties of membranes of biological cells to a considerable degree determine those processes capable of maintaining the vigour both of cells themselves and the body as a whole. Alterations of rheologic properties of blood are regarded as one of the most important parameters in the course of the pathologic process in bronchial asthma. Patients with bronchial asthma revealed appreciable alterations of erythrocyte morphofunctional condition, which make for disturbances in the terminal perfusion secondary to blockage of microvessels by rigid cells and cell aggregates.