[Transcranial magnetic stimulation in the treatment of depressive disorder in Parkinson's disease]. / Primenenie transkranial'noi magnitnoi stimulyatsii v lechenii depressivnogo rasstroistva pri bolezni Parkinsona.

The prevalence of affective disorders in patients with Parkinson's disease (PD) is significantly higher than in the general population of people of the same age. It is known that the effectiveness of antidepressants in PD with depressive disorder is lower than in patients with primary depression. For depression resistant to standard treatments, other therapeutic strategies are available. Transcranial magnetic stimulation (TMS) is one of the most popular and safe brain stimulation methods that has been successfully used to treat primary depression. The accumulation of experience in the use of TMS has made it possible to expand the application of the method to other diseases, including PD. The article provides literature data on the use of different TMS protocols for the treatment of depressive disorder in patients with PD.

[Premorbid self-medication and its factors in patients with depressive and neurotic disorders]. / Samomedikatsiia i faktory ee formirovaniia u patsientov s depressivnymi i nevroticheskimi rasstroistvami v domanifestnom periode.

AIM: To study self-medication and its factors in patients with depressive and neurotic disorders at premorbid stage. MATERIAL AND METHODS: The sample included 131 first-time admitted patients and 85 recurrent patients with depressive or neurotic disorders, who reported taking medication to cope with the symptoms during preadmission period. Lazarus coping strategies test, Shmishek personality test, test on disease attitude and patient activation were used. Social and demographic characteristics, subjective characteristics of disease, medical literacy and behavioral coping strategies were studied. RESULTS AND CONCLUSION: Over 50% of the patients used self-medication to cope with the symptoms during the preadmission period. Coping anxiety and insomnia was a key motivation to self-medication. Most frequently used medications included tranquilizers and herbal anxiolytics. Misunderstanding of origin of their state, searching for information about treatment of disease via internet, increased emotiveness and tension, lack of their correction with psychotherapy were the factors of self-medication.

[A multiple linear model of help-seeking behavior in patients with depressive and neurotic disorders]. / Mnogofaktornaia model' povedeniia patsientov po obrashchaemosti za meditsinskoi pomoshch'iu pri depressivnykh i nevroticheskikh rasstroistvakh.

AIM: To find out the factors effecting time from onset of symptoms of psychiatric disorders to help-seeking. MATERIAL AND METHODS: The sample included 166 inpatients with affective or neurotic, stress-related and somatoform disorders. Clinical, psychometric, anamnestic methods were used. RESULTS AND CONCLUSION: The multiple regression model of help-seeking by inpatients with depressive and neurotic disorders is characterized by the high level of multiple correlation (r=0.85). This model allows the prediction of the time of help-seeking in the group of inpatients or individually, which can be used as a basis for programs of prevention of delayed help-seeking behavior.

[Clinical, pathogenetic and therapeutic aspects of panic disorder in patients with chronic alcoholism (review)].

Comorbid diagnosis of panic disorder and alcoholism is common in clinical practice. There are several theories that explained the comorbidity but no one of them has been completely proved. Sequence of disease manifestation in patients with comorbid pathologies remains unclear but different combinations may exist. Many studies suggest that anxiety disorders precede the development of alcoholism. Moreover, the prospective research has revealed that panic disorder is a highly significant predictor of alcoholism. The effectiveness of therapy was shown to be several times lower in the presence of comorbid anxiety disorders. At the same time, the problems of adequate therapy of patients with comorbid pathology remain unsolved.