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Eur J Clin Pharmacol ; 51(5): 355-8, 1997.
Artículo en Inglés | MEDLINE | ID: mdl-9049574

RESUMEN

OBJECTIVE: A randomised, controlled clinical trial was performed to study the long-term effect of gradual withdrawal from benzodiazepines on the daily functioning of residents of homes for the elderly. The planned sample size was not achieved due to recruitment and follow-up problems. RESULTS: The results in this small sample nevertheless suggest that gradual withdrawal from benzodiazepines is possible in residents of homes for the elderly, and that it can have a positive effect on their daily functioning. No major withdrawal symptoms were observed, although there was a decrease in sleep quality during withdrawal. CONCLUSION: The findings are promising for further research, but researchers should anticipate the problems inherent in executing a trial with institutionalised elderly subjects.


Asunto(s)
Benzodiazepinas/administración & dosificación , Síndrome de Abstinencia a Sustancias , Anciano , Anciano de 80 o más Años , Cognición/efectos de los fármacos , Método Doble Ciego , Utilización de Medicamentos , Estudios de Factibilidad , Femenino , Hogares para Ancianos , Humanos , Masculino , Pautas de la Práctica en Medicina , Trastornos del Inicio y del Mantenimiento del Sueño/tratamiento farmacológico , Factores de Tiempo
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