[PROCUREMENT OF SANITARY AND EPIDEMIOLOGICAL WELFARE IN THE REGION OF-CITY-RESORT SOCHI FOR DANGEROUS AND NATURAL-FOCI INFECTIOUS DIS- EASES IN 2015].

AIM: Analysis ofresults of epidemiologic monitoring especially dangerous, natural-foci and other infectious diseases, asill as epizootologic activity of natural foci of infection on,the terri- tory, of city-resort Sochi. MATERIALS AND METHODS: Laboratory studies of 820. samples by PCR; im- mune- and bacteriologic methods were carried out, among those 344 - clinical material, 12 - water from open bodies and 321 - field material. Molecular-genetic identification of-143 strains of Vibrio-cholerae, isolated from open water bodies of city-resort Sochi, was-carried out,. RESULTS: Circulation of causative agents of Q fever, tularemia and hemorrhagic fever with renal syndrome of Dobrava-Adler genotypes was established, -as well as rickettsia of tick spotted fever group Predomination of rotaviruses (70.9%) was detected during study of samples of clinical material in etiologic structure of sporadically emerging acute intestine infections. Relatively high temperature values of river water during summer months (from 18, to 30 C), exit of sulfide mineral waters into the riverbed, that create-alkaline medium, seasonal reduction of river debit and speed of water current facilitated sustenance of contamination of water of Agura river by V.cholerae. CONCLUSION: Activity of natural foci of the infectious disease and contamination of Agura iver by V.cholerae Ο1, (atoxigenic) gives evidence on the necessity of constant control of epidemiologic situation by dangerous and natural-foci infectious diseases on the territory of city-resort Sochi, as well as study regional features, of their causative agents, including using genetic methods.

[Spatial structure of natural foci of hantavirus on the territory of Northwestern Caucasus].

For the period from 2001 to 2011 zoological and epizootological studies in more than 100 points of Northwestern Caucasus including territories of Krasnodar Region and Republic of Adygea were carried out. 8723 specimens of small mammals represented by 20 rodent species and 7 insectivorous species were captured and examined. Organs and blood from 5057 specimens of creatures were studied for hantavirus infection. The presence of natural foci of circulation of 2 species of hantavirus--Dobrava/Belgrade and Tula--was established. Sochi viruses and presumably Kurkin with main natural hosts--Caucasian wood and field mice belong to the first species. Tula and Adler viruses with the main host--Microtus genus vole belong to the second species. Quantitative characteristics of infection of small mammals of various species during different seasons and years on the examined territories were obtained, that allowed to create a map of allocation of foci of hantavirus circulation that differ by structure.

[A case of Crimean-Congo hemorrhagic fever in the Anapa District, Krasnodar Territory].

The paper gives information on the first case of Crimean-Congo hemorrhagic fever detected in a female resident of the Anapa District, Krasnodar Territory, in 2005 in the past 57 years.

[First evidence for breeding Aedes aegypti L in the area of Greater Sochi and in some towns of Abkhasia].

A preliminary survey of some widely spaced settlements in Greater Sochi (and in the city of Sochi) in a period of late July to early October 2007 has revealed man-biting females and swarming males of Aedes aegypti females indoors and outdoors. Man-biting Ae. aegypti females, like males swarming nearby, were also present in the town of Gudauta under study in September (the males and females of this species were found on one-day youngsters in the animal houses) and in the suburbs of the town of Sukhumi (Republic of Abkhazia). Ae. aegypti breeding places and larvae were revealed at the back of houses in Gudauta. Detection of not only males, but also females and preimagoes of this species suggests that a local breeding Ae. aegypti population is available in this area. The findings show that a local breeding population of Ae. aegypti mosquitoes has reemerged in the inspected area of the Black Sea coast (Tuapse-Sukhumi) with a humid Mediterranean climate after 35-40-year absence. Prevention of outbreaks of menacing human arbovirus diseases in the importation of their pathogens to the health resort-tourist area of the Caucasian Black-Sea coast requires urgent organization of a continuous entomological service for environmental monitoring, organization, and implementation of measures to eradicate Ae. aegypti.

[The epizootological and virological characteristics of a natural hantavirus infection focus in the subtropic zone of the Krasnodarsk Territory].

A natural focus of hantavirus infection was detected and examined during the studies conducted in 2000-2002 around the Sochi (the western spurs of the Great Caucasus Ridge, which descended to the Black Sea (the Krasnodar Territory of Russia). At least 4 rodent species, such as Microtus majori, A. (S.) ponticus, A. agrarius, A. (S.) ciscaucasicus, were shown to participate in the circulation of hantaviruses. A comparative analysis of the nucleotide sequences of genomic S- and M-segments of hantaviruses has provided evidence that 13 viral RNA isolates from the A. (S.) ciscaucasicus belong to the Dobrava/Belgrade virus clade; however the RNA isolate from the Microtus majori belong to the Tula virus clade.