[Low back pain in daily clinical practice; article for education and training purposes]. / Lagerugpijn.

Low back pain is a very common reason for patient visits to a general practitioner or medical specialist. It is associated with a negative effect on daily living and high costs of care. The differential diagnosis of low back pain is extensive, and usually no specific cause can be identified. In such a case, we speak of non-specific low back pain. In this article, we present practical pointers to recognising specific causes of low back pain and answer some frequently-asked questions regarding the diagnosis and treatment of low back pain.

[Application of new glucose lowering drugs: DPP-4 inhibitors, GLP-1 receptor agonists and SGLT-2 inhibitors]. / Toepassing van nieuwe bloedglucoseverlagende middelen.

A comprehensive review of the literature on DPP-4 inhibitors, GLP-1 receptor agonists and SGLT-2 inhibitors has resulted in small changes to the medication roadmap of the type 2 diabetes mellitus standard of the Dutch College of General Practitioners. SGLT-2 inhibitors and GLP-1 receptor agonists may have benefits related to cardiovascular outcomes in patients with high cardiovascular risk, especially in those who have experienced a cardiovascular event. However, ascribing effectiveness related to cardiovascular outcomes on the basis of a single cardiovascular safety trial is premature. Metformin, sulfonylurea derivatives and insulin are still the cornerstone of type 2 diabetes mellitus treatment in primary care.