Comparison between Accelerated Partial Breast Irradiation with multicatheter interstitial brachytherapy and Whole Breast Irradiation, in clinical practice

PurposeThe aim of this study was to compare accelerated partial breast irradiation (APBI) with multicatheter interstitial brachytherapy (BT) and whole breast irradiation (WBI), in terms of toxicity, aesthetic result, quality of life and survival, in clinical practice.Materials and methodsA comparative study of two prospectively recorded cohorts of 76 breast cancer patients who complied with the recommendations of GEC-ESTRO for APBI was conducted. The main objective was toxicity, quality of life measured through validated questionnaires and the aesthetic results. Secondary objectives were overall survival and disease-free survival.ResultsSeventy-six stage I/II breast cancer patients, with a mean age of 66 years entered the study. APBI group showed less acute G1-2 dermatitis (51.4 vs 94.9%, p < 0.001) and late hyperpigmentation (0 vs 17.9%, p = 0.04). There were no differences in aesthetic results, both assessed by the patient herself and by the doctor. Statistically significant differences in measures of quality of life were observed in favour of the APBI, both in EORTC QLQ-BR23 and body image scale questionnaires. With a median follow-up of 72 months (6 years), the estimated overall survival at 5 and 10 years was 96.8 and 77.7%, respectively, and disease-free survival at 5 and 10 years was 91.1 and 69.4%, respectively, without statistically significant differences between groups.DiscussionAPBI is an attractive alternative in candidate patients with initial breast cancer, with benefits in acute toxicity and quality of life and fewer visits to the hospital, without compromising tumor control or survival.

Plasmocitoma solitario coroideo. Presentación de un caso / Solitary plasmacytoma of the choroid. A case report

Antecedentes: el plasmocitoma solitario es una lesión bien conocida de localización heterogénea si bien su presencia en el globo ocular es del todo infrecuente. Material y método: presentamos un caso de plasmocitoma solitario coroideo haciendo hincapié en las características histológicas y en su diagnóstico diferencial. Resultados: la negatividad de los estudios clínicos y analíticos será fundamental para descartar el mieloma múltiple. Conclusiones: se trata de una patología que se suele asociar a un buen pronóstico

Introduction: solitary plasmacytoma is a well known lesion with heterogeneous location uncommon in the eye. Material and methods: we report a case of solitary plasmacytoma in the choroid studying the histology and the differential diagnosis. Results: negativity of clinical and analytical studies are essential in order to rule out multiple myeloma. Conclusions: plasmacytoma is an entity associated with good prognosis (AU)