[Cardiovascular manifestations of seronegative inflammatory spondyloarthropathies]. / Zmiany w ukladzie sercowo-naczyniowym w przebiegu seronegatywnych spondyloartropatii zapalnych.

Cardiovascular manifestations of seronegative spondyloarthropathies represent an important clinical problem which has not been fully elucidated. Clinically significant cardiovascular symptoms are present in 10% of patients with ankylosing spondylitis (AS), usually in the case of long-standing disease. The following echocardiographic abnormalities have been reported in AS: ascending aortitis, aortic insufficiency (1-34%), mitral insufficiency (1-76%), mitral valve prolapse (5.7-10%), and diastolic dysfunction (20-50%). Abnormalities of the cardiac conduction system may develop in 1% to 33% of AS patients as a consequence of postinflammatory scarring of the myocardium. Cardiovascular diseases are the leading cause of death (36.2%) of patients with psoriatic arthritis (PsA). The risk of death in PsA is 1.3 times greater than in the general population. The following echocardiographic abnormalities can be seen in PsA: fibrinous pericarditis (18.2%), myocarditis (15.9%), and valvular disease (5.7%). Diastolic dysfunction in PsA correlates with the presence of articular lesions and duration of psoriasis. The importance of a thorough investigation of the cardiovascular system in patients with seronegative spondyloarthropathies is emphasized.

[Ear involvement in Wegener's granulomatosis]. / Zajecie narzadu sluchu w ziarniniaku Wegenera.

Clinical manifestation of Wegener's granulomatosis could be multiorgan. Authors present the review of literature concerning on inflammatory changes in ears that in consequence could lead to hearing impairment or deafness.

[Hemochromatosis--disease of concern of rheumatologist]. / Hemochromatoza--choroba, takze reumatologiczna.

Hemochromatosis is an congenital metabolic disorder depending on increase in intestinal iron absorbtion. That result in many systemic disorders and organ failure including arthralgia, occuring usually between 30 and 50 year of life. These symptoms precede liver cirrhosis with few years. We are describing the case of 40 years man with seronegative arthritis diagnosed for hemochromatosis proven in further diagnostics.