Simultaneous pseudospin and valley topological edge states of elastic waves in phononic crystals made of distorted Kekulé lattices.

Topological metamaterials protected by the spatial inversion symmetry mainly support single type edge state, interpreted by either the quantum valley Hall effect or the quantum spin Hall effect. However, owing to the existence of the complicated couplings and waveform conversions during elastic wave propagation, realizing topologically protected edge states that support both pseudospin and valley degrees of freedom in elastic system remains a great challenge. Here, we propose a two-dimensional Kekulé phononic crystal (PC) that can simultaneously possess pseudospin- and valley-Hall edge states in different frequency bands. By inhomogeneously changing the elliptical direction in a Kekulé lattice of elliptical cylinders, three complete phononic bandgaps exhibiting distinct topological phase transitions can be obtained, one of which supports a pair of pseudospin-Hall edge states and the other hosts valley-Hall edge states in the low and high frequency regime. Furthermore, a sandwiched PC heterostructure and a four-channel cross-waveguide splitter are constructed to achieve selective excitation and topological robust propagation of pseudospin- and valley-momentum locking edge states in a single configuration. These results provide new possibilities for manipulating in-plane bulk elastic waves with both pseudospin and valley degrees of freedom in a single configuration, which has potential applications for multiband and multifunctional waveguiding.

Integration of organic and inorganic photothermal probes for enhanced photothermometric sensing of silver ions.

A new signal-amplified photothermometric sensor of Ag+ was explored based on a simple yet effective integration of inorganic and organic photothermal probes, mainly depending on the successful exploitation of a dual-signal transduction channel originating from the inherent photothermal property and the peroxidase-like activity of Prussian blue nanocubes (PB NCs).

A two fluorescent signal indicator-based ratio fluorometric alkaline phosphatase assay based on one signal precursor.

Two fluorescent signal indicators were simply converted from one organic precursor system by using the superior oxidation capability of manganese dioxide (MnO2) nanosheets for the first time, finally resulting in the successful fabrication of a ratio fluorometric bioassay of alkaline phosphatase (ALP).

Analysis of N-terminal amino acid sequence of 12 000-protein in gingival crevicular fluid and its clinical significance.

OBJECTIVES: To study the essence of N-terminal amino acid sequence of 12 000-protein in gingival crevicular fluid (GCF). METHODS: GCF samples from patients with RPP and AP were collected. 12 000-protein was separated by SDS-PAGE and transformed to PVDF by electronic transformation. The aim band was cut to be analyzed in 491 Protein Sequencer. RESULTS: The first ten of N-terminal amino acid sequence of 12 000-protein in GCF was Met, Leu, Thr, Glu, Leu, Glu, Lys, Ala, Leu, Asn. Through checking up in MS-Edman, the sequence was similar to "Ca binding protein, MRP8" which is the light subunit of Calprotectin. CONCLUSIONS: Calprotectin is a major protein in granulocytes and monocytes, and is related to many inflammatory diseases, maybe served as a effective marker for evaluating the inflammation of periodontium.