Interventional micro-axial flow blood pump is widely used as an effective treatment for patients with cardiogenic shock. Hemolysis and coagulation are vital concerns in the clinical application of interventional micro-axial flow pumps. This paper reviewed hemolysis and coagulation models for micro-axial flow blood pumps. Firstly, the structural characteristics of commercial interventional micro-axial flow blood pumps and issues related to clinical applications were introduced. Then the basic mechanisms of hemolysis and coagulation were used to study the factors affecting erythrocyte damage and platelet activation in interventional micro-axial flow blood pumps, focusing on the current models of hemolysis and coagulation on different scales (macroscopic, mesoscopic, and microscopic). Since models at different scales have different perspectives on the study of hemolysis and coagulation, a comprehensive analysis combined with multi-scale models is required to fully consider the influence of complex factors of interventional pumps on hemolysis and coagulation.
Blood Coagulation , Heart-Assist Devices , Hemolysis , Humans , Erythrocytes/cytology , Erythrocytes/physiology , Shock, Cardiogenic/therapy , Platelet Activation , Equipment Design
Frequency tracking and amplitude control are essential for piezoelectric transducers. Frequency tracking ensures the piezoelectric transducer operates at the resonant frequency for maximum power output, and amplitude control regulates the mechanical motion of the output. This paper presents a novel driver based on a push-pull inverter for piezoelectric transducers. The proposed driver realizes the frequency tracking and amplitude control scheme by a voltage sensing bridge in the case of transformer secondary matching, guaranteeing automatic frequency tracking and precise mechanical functions regardless of environmental and load variations. The proposed scheme is verified by the ultrasonic scalpel and the ultrasonic motor (USM). The experimental results show that this scheme reduces the build-up time from 10 ms to 3 ms and loaded frequency variations from 250 Hz to 200 Hz. In addition, the amplitude control performance was further observed on USM for various loads. The overshoot is less than 5.4% under different load torques. Therefore, the proposed scheme improves the load adaptability and stability of piezoelectric transducers and promotes the application of piezoelectric transducers under various conditions.
