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Anti-Bacterial Agents (1)

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Bifunctional asymmetric catalysis: a tandem nucleophile/Lewis acid promoted synthesis of beta-lactams.

France, Stefan; Wack, Harald; Hafez, Ahmed M; Taggi, Andrew E; Witsil, Daniel R; Lectka, Thomas.

Org Lett ; 4(9): 1603-5, 2002 May 02.

Article En | MEDLINE | ID: mdl-11975639

[reaction: see text]. We describe a superior procedure for the catalytic, asymmetric synthesis of beta-lactams using a bifunctional catalyst system consisting of a chiral nucleophile and an achiral Lewis acid.

Anti-Bacterial Agents/chemical synthesis , Catalysis , Indicators and Reagents , Magnetic Resonance Spectroscopy , Metals/chemistry , Stereoisomerism , beta-Lactams

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(instance:"regional") AND ( year_cluster:("2002") AND pais_afiliacao:("^iUnited States^eEstados"))(instance:"regional") AND ( year_cluster:("2002") AND pais_afiliacao:("^iUnited States^eEstados"))(instance:"regional") AND ( year_cluster:("2002") AND pais_afiliacao:("^iUnited States^eEstados"))(instance:"regional") AND ( year_cluster:("2002") AND pais_afiliacao:("^iUnited States^eEstados"))

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