Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 6 de 6
Filtrar
Más filtros










Base de datos
Intervalo de año de publicación
1.
Sensors (Basel) ; 20(19)2020 Sep 25.
Artículo en Inglés | MEDLINE | ID: mdl-32992878

RESUMEN

Water-soluble chemicals, involving a wide range of toxic chemicals in aqueous solutions, remain essential in both daily living or industrial uses. However, most toxicants are evaporated with water through their use and thus cause deleterious effects on the domestic environment and health in humans. Unfortunately, most current low-dose chemical vapor detection technologies are restricted by the use of sophisticated instruments and unable to promptly detect the quantity of diverse toxicants in a single analysis. To address these issues, this study reports the development of simple and fast chemical vapor detection using doctor-blade-coated macroporous poly(2-hydroxyethyl methacrylate)/poly(ethoxylated trimethylolpropane triacrylate) photonic crystals, in which the poly(2-hydroxyethyl methacrylate) has strong affinity to insecticide vapor owing to a favorable Gibbs free energy change for their mixing. The condensation of water-soluble chemical vapor therefore results in a significant reflection peak shift and an obvious color change. The visual colorimetric readout can be further improved by increasing the lattice spacing of the macroporous photonic crystals. Furthermore, the dependence of the reflection peak position on vapor pressure under actual conditions and the reproducibility of vapor detecting are also evaluated in this study.

2.
Ying Yong Sheng Tai Xue Bao ; 31(12): 4125-4133, 2020 Dec.
Artículo en Chino | MEDLINE | ID: mdl-33393250

RESUMEN

Under rapid industrialization and urbanization, the conservation and management of agricultural heritage systems is facing many threats and challenges, such as the massive outflow of working labor, land abandonment, and the difficulty in maintaining traditional knowledge systems. Promoting land transfer and carrying out moderate-scale management play an active role in the conservation of agricultural heritage systems. While land transfer brings economic benefits to heritage sites, its environmental impacts to heritage sites are worthy of attention. However, empirical studies are scarce. This study took Qingtian rice-fish culture system in Zhejiang Province as an example, which was designated as Globally Important Agricultural Heritage Systems (GIAHS) in 2005. Small farmer management model and land scale management model were distinguished, while the life cycle method was used to calculate the carbon footprints of two models. The results showed that the carbon footprints of small farmer management model and land scale management model were 6510.80 and 5917.00 kg CO2-eq·hm-2, respectively, while the carbon footprints per unit output were 0.13 and 0.10 kg CO2-eq·yuan-1, respectively. Compared with small farmer management model, land scale management model had lower greenhouse gas emission and lower environmental impact of per unit output. As farmers expanded the scale of land management, local greenhouse gas emissions had been reduced by 4097.20 kg CO2-eq. Furthermore, the accumulation of CH4 in agricultural production accounted for the largest proportion of carbon footprint. The input of compound fertilizer among agricultural production materials was next to CH4 accumulation, becoming the second largest source of greenhouse gas emission. Corn and wheat being used as fish feed also had a significant impact on greenhouse gas emission in small farmer management model. Therefore, the promotion of moderate scale land management is conducive to the win-win of economic and environmental benefits of traditional agricultural systems and plays an important role in the conservation of agricultural heritage systems.


Asunto(s)
Huella de Carbono , Oryza , Agricultura , Animales , Fertilizantes , Triticum
3.
Hum Mol Genet ; 26(20): 3909-3921, 2017 10 15.
Artículo en Inglés | MEDLINE | ID: mdl-29016849

RESUMEN

Impaired clearance of amyloid-ß peptide (Aß) leads to abnormal extracellular accumulation of this neurotoxic protein that drives neurodegeneration in sporadic Alzheimer's disease (AD). Connective tissue growth factor (CTGF/CCN2) expression is elevated in plaque-surrounding astrocytes in AD patients. However, the role of CTGF in AD pathogenesis remains unclear. Here we characterized the neuroprotective activity of CTGF. We found that CTGF facilitated Aß uptake and subsequent degradation within primary glia and neuroblastoma cells. CTGF enhanced extracellular Aß degradation via membrane-bound matrix metalloproteinase-14 (MMP14) in glia and extracellular MMP13 in neurons. In the brain of a Drosophila AD model, glial-expression of CTGF reduced Aß deposits, improved locomotor function, and rescued memory deficits. Neuroprotective potential of CTGF against Aß42-induced photoreceptor degeneration was disrupted through silencing MMPs. Therefore, CTGF may represent a node for potential AD therapeutics as it intervenes in glia-neuron communication via specific MMPs to alleviate Aß neurotoxicity in the central nervous system.


Asunto(s)
Péptidos beta-Amiloides/toxicidad , Factor de Crecimiento del Tejido Conjuntivo/metabolismo , Enfermedad de Alzheimer/metabolismo , Péptidos beta-Amiloides/metabolismo , Animales , Animales Modificados Genéticamente , Astrocitos/metabolismo , Encéfalo/metabolismo , Factor de Crecimiento del Tejido Conjuntivo/fisiología , Modelos Animales de Enfermedad , Drosophila , Humanos , Metaloproteinasa 14 de la Matriz/metabolismo , Ratones , Neuroglía/metabolismo , Neuroglía/fisiología , Neuronas/metabolismo , Neuronas/fisiología , Fármacos Neuroprotectores/metabolismo , Fármacos Neuroprotectores/farmacología , Síndromes de Neurotoxicidad/metabolismo , Fragmentos de Péptidos/metabolismo , Placa Amiloide/metabolismo , Ratas
4.
Ying Yong Sheng Tai Xue Bao ; 28(1): 299-307, 2017 Jan.
Artículo en Chino | MEDLINE | ID: mdl-29749215

RESUMEN

Rice field can provide habitat for fish and other aquatic animals. Rice-fish coculture can increase rice yield and simultaneously reduce the use of chemicals through reducing rice pest occurrence and nutrient complementary use. However, how fish uses food sources (e.g. phytoplankton, weeds, duckweed, macro-algal and snail) from rice field, and whether the nutrients releasing from those food sources due to fish transforming can improve rice growth are still unknown. Here, we conducted two field experiments to address these questions. One was to investigate the pattern of fish activity in the field using the method of video recording. The other was to examine the utilization of field resources by fish using stable isotope technology. Rice growth and rice yield were also exa-mined. Results showed that fish tended to be more active and significantly expanded the activity range in the rice-fish coculture compared to fish monoculture (fish not living together with rice plants). The contributions of 3 potential aquatic organisms (duckweed, phytoplankton and snail) to fish dietary were 22.7%, 34.8% and 30.0% respectively under rice-fish coculture without feed. Under the treatment with feed, however, the contributions of these 3 aquatic organisms to the fish die-tary were 8.9%, 5.9% and 1.6% respectively. The feed contribution was 71.0%. Rice-fish coculture significantly increased the nitrogen concentration in rice leaves, prolonged tillering stage by 10-12 days and increased rice spike rate and yield. The results suggested that raising fish in paddy field may transform the nutrients contained in field resources to bioavailable for rice plants through fish feeding activity, which can improve rice growth and rice yield.


Asunto(s)
Técnicas de Cocultivo , Peces , Oryza , Animales , Ecosistema , Hojas de la Planta
5.
Shanghai Kou Qiang Yi Xue ; 16(4): 436-9, 2007 Aug.
Artículo en Chino | MEDLINE | ID: mdl-17924035

RESUMEN

PURPOSE: To investigate the status of administration of antibiotics drugs for pediatric in-patients in the Department of Oral and Maxillofacial Surgery in our hospital and offer guides for rational use of antibiotics in clinical practice. METHODS: 102 medical records of children from 3 months to 18 years in the Department of Oral and Maxillofacial Surgery in our hospital from the year of 2005-2006 were selected randomly. They were required to fill in the questionnaire which included gender, age, diagnosis of diseases, situation of medicine, laboratory examination, bacterial culture and sensitivity test of medicine. Respective analysis was done over the aspects of the variation of antibiotics medication, duration of medication, drug combination, various choices of antibiotics during the treatment and the ways of administration. A conclusion was drawn of whether the administration of antibiotics was rational. RESULTS: The rate of antibiotics administration was 94.12%, and the rates of single drug and combined administration (two drugs) were 74.51% and 19.61% respectively. Intravenous drip was the main way of administration, 54 cases received antibiotics orally, none of them received intramuscular medication. The rate of changing two kinds of antibiotics,three kinds of antibiotics and four kinds of antibiotics were 36.27%,23.53% and 9.8% respectively. The rate of bacterial culture was 1.96%. The rate of duration of medication in less than three days, from three days to seven days and more than seven days were 24.50%,48.04% and 21.57% respectively. The administration frequence was higher in cephalosporins, lincosamides, penecillins category than in other antibiotics. CONCLUSION: Rational use of anti-bacteria drugs was the main trend, however some problems still existed such as prophylactic administration of antibiotics, low delivery ratio of sample collection, irrational use of drugs, frequent change of antibiotics and drug abuse etc. Therefore, more efficient measures should be developed and implemented such as rational layout of wards, enhancing preoperative health care and rational administration of antibiotics etc.


Asunto(s)
Antibacterianos/uso terapéutico , Profilaxis Antibiótica , Cirugía Bucal , Adolescente , Niño , Preescolar , Humanos , Lactante
6.
Hu Li Za Zhi ; 52(5): 33-40, 2005 Oct.
Artículo en Chino | MEDLINE | ID: mdl-16222639

RESUMEN

Hypoxia often occurs in the course of emergency treatment the monitoring systems alarm is not heard promptly by the nurses in attendance. In this study, nurses were monitored for the speed of their reactions to such alarms in 326 clinical instances. In 128 instances (39 percent) the nurses reacted immediately (within ten seconds), and in 198 instances (61 percent) the nurses took more than ten seconds to react. In relation to the reactions that took longer than ten seconds, it was discovered that there was: a lack of alertness about dealing with alarms, insufficient knowledge about setting alarms, no coordinated response mechanism, a failure to hear the alarm, limitations affecting the equipment and difficulty detecting the direction of origin of the alarm sound. For these reasons the hospital implemented briefings about alarms during morning meetings, a coordinated response mechanism, improvements in standards concerning the setting and inspection of alarms, the setting of limits on the frequency of patient's visits and the numbers of visitors, and the setting of a standard alarm volume level. As a result, the percentage of nurses responding to alarms within ten seconds increased to eighty percent, raising standards of nursing care, medical treatment and patient safety.


Asunto(s)
Falla de Equipo , Monitoreo Fisiológico/instrumentación , Humanos , Seguridad , Factores de Tiempo
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...