Iterative List Patterned Reed-Muller Projection Detection-Based Packetized Unsourced Massive Random Access.

In this paper, we consider a slot-controlled coded compressed sensing protocol for unsourced massive random access (URA) that concatenates a shared patterned Reed-Muller (PRM) inner codebook to an outer error-correction code. Due to the limitations of the geometry-based decoding algorithm in single-sequence settings and due to the message interference that may result in decreased decoding performance under multi-sequence circumstances, a list PRM projection algorithm and an iterative list PRM projection algorithm are proposed to supplant the signal detector associated with the inner PRM sequences in this paper. In detail, we first propose an enhanced path-saving algorithm, called list PRM projection detection, for use in single-user scenarios that maintains multiple candidates during the first few layers so as to remedy the risk of spreading errors. On this basis, we further propose an iterative list PRM projection algorithm for use in multi-user scenarios. The vectors for PRM codes and channel coefficients are jointly detected in an iterative manner, which offers significant improvements regarding the convergence rate for signal recovery. Furthermore, the performances of the proposed algorithms are analyzed mathematically, and we verify that the theoretical simulations are consistent with the numerical simulations. Finally, we concatenate the inner PRM codes that employ iterative list detection in two practical error-correction outer codes. According to the simulation results, we conclude that the packetized URA with the proposed iterative list projection detection works better than benchmarks in terms of the number of active users it can support in each slot and the amount of energy needed per bit to meet an expected error probability.

Patterned Reed-Muller Sequences with Outer A-Channel Codes and Projective Decoding for Slot-Controlled Unsourced Random Access.

We propose a novel slot-pattern-control based coded compressed sensing for unsourced random access with an outer A-channel code capable of correcting t errors. Specifically, an RM extension code called patterned Reed-Muller (PRM) code is proposed. We demonstrate the high spectral efficiency due to its enormous sequence space and prove the geometry property in the complex domain that enhances the reliability and efficiency of detection. Accordingly, a projective decoder based on its geometry theorem is also proposed. Next, the "patterned" property of the PRM code, which partitions the binary vector space into several subspaces, is further extended as the primary principle for designing a slot control criterion that reduces the number of simultaneous transmissions in each slot. The factors affecting the chance of sequence collisions are identified. Finally, the proposed scheme is implemented in two practical outer A-channel codes: (i) the t-tree code and (ii) the Reed-Solomon code with Guruswami-Sudan list decoding, and the optimal setups are determined to minimize SNR by optimizing the inner and outer codes jointly. In comparison with the existing counterpart, our simulation results confirm that the proposed scheme compares favorably with benchmark schemes regarding the energy-per-bit requirement to meet a target error probability as well as the number of accommodated active users in the system.

Well-aligned three-dimensional silk fibroin protein scaffold for orientation regulation of cells.

The similar characteristics of biomaterials to the extracellular matrix are essential for efficient tissue repair through dictating cell behaviors. But the scaffold fabrication with complex shapes and controlled alignment have proven to be a difficult task. Herein, a well-designed three-dimensional silk fibroin scaffold is fabricated through ice template technology. The effect of the silk fibroin protein concentration and the freezing temperature on the microstructure and mechanical properties of scaffolds are investigated systematically. Cells behavior mediated by the obtained silk fibroin scaffolds is detected. The results show that the protein concentration plays a vital role in microstructure and scaffold strength. A well-aligned scaffold can be obtained when silk fibroin solution is kept at 12 wt%, which holds the highest mechanical properties. The pore size can be further adjusted in the range of 5-80 µm by changing the freezing temperature from -60 to -196 °C. The well-oriented scaffold with the appropriate pore size of 10-20 µm has the best ability to guide cell alignment. The resulting scaffolds provide an excellent matrix to guide cells behaviors and have a potential application in tissue engineering.

Visible Light-Induced Highly Regioselective and Stereoselective Oxysulfonylation of Alkynes for the Synthesis of (E)-ß-Phenoxy Vinylsulfones.

A highly efficient visible light-induced regioselective and stereoselective oxysulfonylation of alkynes with arylsulfonate phenol esters has been developed. This photocatalyst- and metal-free method proceeds smoothly under very mild conditions and exhibits a broad substrate scope, providing (E)-ß-phenoxy vinylsulfones in moderate to excellent yields. Mechanistic studies indicated the involvement of an electron donor-acceptor complex-mediated radical process.

Fabrication of silk fibroin film enhanced by acid hydrolyzed silk fibroin nanowhiskers to improve bacterial inhibition and biocompatibility efficacy.

In this study, silk fibroin nanowhiskers (SNWs) were extracted from natural silk fiber by sulfuric acid hydrolysis with the assistance of ultrasonic wave treatment. The obtained SNWs were mixed with regenerated silk fibroin (RSF) solution to fabricate the SNWs/RSF films. The fabricating SNWs were systematically characterized by using SEM, FTIR, and the SNWs/RSF films were observed by digital camera, PM, etc. The results show that the monodisperse SNWs are evenly distributed in the RSF film. The presence of SNWs in RSF film significantly improves the performances of the film, including the swelling ability, mechanical properties, hydrophilicity, antibacterial efficacy, cytocompatibility. Meanwhile, the SNWs/RSF film can endorse the wound healing efficiency in vivo mice wound site. The proposed techniques for extracting SNWs and fabricating silk fibroin composite film may provide a valuable method for creating an ideal silk-based material for biomedical applications.

Controllable performance of a dopamine-modified silk fibroin-based bio-adhesive by doping metal ions.

Bio-adhesives are essential for wound healing because of their convenience and safety. Although widely used as biomaterials, silk fibroin's (SF's) further application as bio-adhesive is hindered due to its weak stickiness with tissue and slow gelation speed. Here, a dopamine-modified SF-based bio-adhesive is fabricated by using genipin as the chemical cross-linking agent. Furthermore, metal ions have been used to adjust the adhesion property of the bio-adhesive. The experimental results shows that the dopamine-modified SF-based composite holds a better stickiness except slow gelation speed. The doping of Cu2+and Fe3+can accelerate the gelation of the bio-adhesive. Compared with Cu2+, Fe3+has a stronger effect on the gelation speed of the bio-adhesive, which is positive correlative to the concentration of Fe3+. The adhesive has injectability and degradability. In addition, the SF-based adhesive has good biocompatibility and good improvement for cell migrationin vitro. The SF-based bio-adhesive holds potential application in the field of rapid fixation of wounds.