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Biomed Res Int ; 2016: 2015251, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27042657

RESUMEN

INTRODUCTION: Acute kidney injury (AKI) is a common occurrence in the intensive care unit (ICU). Studies have looked at outcomes of renal replacement therapy using intermittent haemodialysis (IHD) in ICUs with varying results. Little is known about the outcomes of using IHD in resource-limited settings where continuous renal replacement therapy (CRRT) is limited. We sought to determine outcomes of IHD among critically ill patients admitted to a low-income country ICU. METHODS: A retrospective review of patient records was conducted. Patients admitted to the ICU who underwent IHD for AKI were included in the study. Patients' demographic and clinical characteristics, cause of AKI, laboratory parameters, haemodialysis characteristics, and survival were interpreted and analyzed. Primary outcome was mortality. RESULTS: Of 62 patients, 40 had complete records. Median age of patients was 38.5 years. Etiologic diagnoses associated with AKI included sepsis, malaria, and ARDS. Mortality was 52.5%. APACHE II (OR 4.550; 95% CI 1.2-17.5, p = 0.028), mechanical ventilation (OR 13.063; 95% CI 2.3-72, p = 0.003), and need for vasopressors (OR 16.8; 95% CI 3.4-82.6, p = 0.001) had statistically significant association with mortality. CONCLUSION: IHD may be a feasible alternative for RRT in critically ill haemodynamically stable patients in low resource settings where CRRT may not be available.


Asunto(s)
Lesión Renal Aguda/terapia , Diálisis Renal/métodos , Choque Séptico/terapia , APACHE , Lesión Renal Aguda/epidemiología , Lesión Renal Aguda/fisiopatología , Adulto , África , Anciano , Enfermedad Crítica , Femenino , Humanos , Unidades de Cuidados Intensivos , Masculino , Persona de Mediana Edad , Diálisis Renal/efectos adversos , Terapia de Reemplazo Renal/métodos , Choque Séptico/epidemiología , Choque Séptico/fisiopatología
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