Layered ternary oxide LiNixMnyCo1-x-yO2 is a promising cathode candidate for high-energy lithium-ion batteries (LIBs). However, the capacity of LIBs is significantly restricted by several factors, including the repeated dissolution-regeneration of the interfacial film at high temperatures, the dissolution of transition metals, and the increase of impedance. Herein, a new precycling strategy in suitable voltage scope at room temperature is proposed to construct a uniform, thermally stable, and insoluble cathode-electrolyte interface (CEI), which helps to maintain stable cycling performances at high temperatures. Specifically, after 5 precycles in the range of 3.85-4.3 V at room temperature, a CEI layer containing numerous inorganic components and oligomers is formed on the surface of LiNi0.6Mn0.2Co0.2O2. Subsequently, the harmful side reactions are effectively suppressed, endowing the cell with an excellent capacity retention of 84.67% after 50 cycles at 0.5C and 55 °C, much higher than that of 65.61% under the conventional film-forming process conditions. This work emphasizes the crucial role of the precycling strategy in regulating the characteristics of CEI layer on the surface of cathode electrode, opening up a new avenue for the high-temperature application of positive electrodes of LIBs.
General movements (GMs) have been widely used for the early clinical evaluation of infant brain development, allowing immediate evaluation of potential development disorders and timely rehabilitation. The infants' general movements can be captured digitally, but the lack of quantitative assessment and well-trained clinical pediatricians presents an obstacle for many years to achieve wider deployment, especially in low-resource settings. There is a high potential to explore wearable sensors for movement analysis due to outstanding privacy, low cost, and easy-to-use features. This work presents a sparse sensor network with soft wireless IMU devices (SWDs) for automatic early evaluation of general movements in infants. The sparse network consisting of only five sensor nodes (SWDs) with robust mechanical properties and excellent biocompatibility continuously and stably captures full-body motion data. The proof-of-the-concept clinical testing with 23 infants showcases outstanding performance in recognizing neonatal activities, confirming the reliability of the system. Taken together with a tiny machine learning algorithm, the system can automatically identify risky infants based on the GMs, with an accuracy of up to 100% (99.9%). The wearable sparse sensor network with an artificial intelligence-based algorithm facilitates intelligent evaluation of infant brain development and early diagnosis of development disorders.
Artificial Intelligence , Movement , Humans , Infant , Movement/physiology , Wearable Electronic Devices , Infant, Newborn , Reproducibility of Results , Male , Female , Algorithms
Hand function rehabilitation training typically requires monitoring the activation status of muscles directly related to hand function. However, due to factors such as the small surface area for hand-back electrode placement and significant skin deformation, the continuous real-time monitoring of high-quality surface electromyographic (sEMG) signals on the hand-back skin still poses significant challenges. We report a stretchable, flexible, breathable, and self-adhesive epidermal sEMG sensor system. The optimized serpentine structure exhibits a sufficient stretchability and filling ratio, enabling the high-quality monitoring of signals. The carving design minimizes the distribution of connecting wires, providing more space for electrode reservation. The low-cost fabrication design, combined with the cauterization design, facilitates large-scale production. Integrated with customized wireless data acquisition hardware, it demonstrates the real-time multi-channel sEMG monitoring capability for muscle activation during hand function rehabilitation actions. The sensor provides a new tool for monitoring hand function rehabilitation treatments, assessing rehabilitation outcomes, and researching areas such as prosthetic control.
Background and aim: Direct posterior reduction and manipulation of the C1-2 joints, accompanied by placement of spacers, is the state-of-the-art technique for treating basilar invagination (BI) and atlantoaxial dislocation (AAD). The hindrance of occiput to reaching up to the true atlantoaxial facets (AAF) during the surgery remains challenging for cage placement. The aim of this study was to explore an objective and precise method of measuring the effect of the hindrance of occiput to reaching up to the true AAF and cage placement during surgery. Method: We collected the clinico-imaging data of 58 patients with BI and AAD (Group A) who underwent surgery in our hospital, and 78 control cohorts (Group B) were retrieved retrospectively. We measured facet-occiput slope angle (FOSA) in midsagittal CT. Patients were positioned prone for surgery based on preoperative flexion O-C2a, and access to the true AAF was observed intraoperatively. The cut-off value of FOSA for the feasibility of cage placement in BI and AAD patients was appointed when access to the true AAF was impossible due to the hindrance of occiput during surgery. Results: The cut-off value of FOSA for the feasibility of cage placement was 34o with an area under the curve AUC of 0.800 (95 % CI: 0.672-0.928, P < 0.001) and the Youden index of 0.607. In patients with FOSA >34o, reaching up to the true AAF and 3D-printed cage placement was impossible. FOSA was negative in Group A and positive in Group B, significantly larger in females compared to males in both groups and significantly larger postoperatively in Group A. Conclusion: FOSA can objectively measure the feasibility of cage placement when the patient is positioned prone per preoperative flexion O-C2a. A FOSA >34o is contraindication for cage placement.
Nickel plating electrolytes prepared by using a simple salt solution can achieve nickel plating on laser-induced graphene (LIG) electrodes, which greatly enhances the electrical conductivity, electrochemical properties, wear resistance, and corrosion resistance of LIG. This makes the LIG-Ni electrodes well suited for electrophysiological, strain, and electrochemical sensing applications. The investigation of the mechanical properties of the LIG-Ni sensor and the monitoring of pulse, respiration, and swallowing confirmed that the sensor can sense insignificant deformations to relatively large conformal strains of skin. Modulation of the nickel-plating process of LIG-Ni, followed by chemical modification, may allow for the introduction of glucose redox catalyst Ni2Fe(CN)6 with interestingly strong catalytic effects, which gives LIG-Ni impressive glucose-sensing properties. Additionally, the chemical modification of LIG-Ni for pH and Na+ monitoring also confirmed its strong electrochemical monitoring potential, which demonstrates application prospects in the development of multiple electrochemical sensors for sweat parameters. A more uniform LIG-Ni multi-physiological sensor preparation process provides a prerequisite for the construction of an integrated multi-physiological sensor system. The sensor was validated to have continuous monitoring performance, and its preparation process is expected to form a system for non-invasive physiological parameter signal monitoring, thus contributing to motion monitoring, disease prevention, and disease diagnosis.
The electrode/electrolyte interface (EEI) is a research hotspot in lithium-ion batteries, while the electrolyte solvation complex can be regarded as a factor that cannot be ignored in determining the performance of the EEI. From the perspective of the electrolyte solvation complex, this review summarizes the effects of solvation complexes on the composition of an EEI film and the Li+ desolvation process, and further clarifies the internal mechanism of the electrolyte composition controlling solvation chemistry. Finally, combined with doubtful points that are not comprehensively considered in the regulation of solvated complexes, this review puts forward some cutting-edge views, which are of great significance for future guidance in improving the performance of lithium-ion batteries.
Sepsis is caused by bacterial infections or viral infections. Clinically, there exist confirmed or highly suspected infection foci. Mortality caused by septic shock remains in a high rate even though antibiotic treatment works effectively. In this study, we treat THP-1 cells with 1 ug/mL LPS (lipopolysaccharide) and add paeoniflorin or LR-12 inhibitor. TREM-1 (triggering receptor expressed on myeloid cells-1), IL-6, IL-1ß, and TNF-α (tumour necrosis factor alpha (a)-cachectin) were detected by ELISA and qRT-PCR, and western blotting is performed to detect related proteins in the NF-κB signaling pathway. As a result, paeoniflorin can significantly reduce the production of LPS-stimulated TREM-1 as well as inflammatory factors and attenuate the phosphorylation of NF-κB signaling pathway-related factors, such as p65 and IκBα. At the same time, the combined effect of paeoniflorin and LR-12 is more significant. The results of this study solidly prove that paeoniflorin plays a role in inhibiting TREM-1-mediated inflammation and the NF-κB pathway could be a potential mechanism of action.
Lipopolysaccharides , NF-kappa B , Glucosides , Humans , Inflammation/drug therapy , Lipopolysaccharides/pharmacology , Monoterpenes , NF-kappa B/metabolism , THP-1 Cells , Triggering Receptor Expressed on Myeloid Cells-1/metabolism , Tumor Necrosis Factor-alpha/metabolism , Tumor Necrosis Factor-alpha/pharmacology
Epoxy polymer-based dielectric materials play a crucial role in advanced electronic devices and power equipment. However, high voltage-stress applications impose stringent requirements, such as a high dielectric strength, on epoxy polymers. Previously reported studies have shown promising material architectures in the form of epoxy polymer-nanoparticle dielectrics, which can restrict the movement of high-energy electrons by the interface charge traps associated with the various interfacial regions. However, these high-energy electrons inevitably traverse the epoxy polymer matrix and destroy the molecular structure, thereby creating a weak link for dielectric breakdown. In this study, a general strategy is developed to improve the dielectric strength by constructing interface charge traps in the molecular structure of the epoxy polymer matrix, using the -CF3 group in partial replacement of the -CH3 group. The proposed strategy increases the dielectric strength (39.5 kV mm-1) and surface breakdown voltage (26.9 kV) of the epoxy polymer matrix by 22.08% and 13.3%, respectively, because the interface charge trap hinders the movement of high-energy electrons. At the same time, the strategy does not degrade the mechanical and thermal properties. The results hold potential for wide application in the manufacturing of advanced future electrical and electronic equipment requiring resilience to high-voltage stress.
The purpose of this study was to investigate metal artifact reduction effect of orthopedics metal artifact reduction (O-Mar) algorithm in computer tomography (CT) image of patients who have undergone total hip arthroplasty (THA) or total knee arthroplasty (TKA).35 cases of patients who underwent TKA or THA have been recruited in this study. CT image of hip or knee joint was obtained with Philips 256-row CT scanner. Tube voltages of 120 and 140âkilovolt peak (KVP) were set. Afterwards, CT image was reconstructed by O-Mar algorithm to reduce metal artifact. Grade of image quality and severity of metal artifact would be taken into qualitative evaluation. While, quantitative evaluation mainly included measurement of metal artifact volume and 2D measurement of average CT value in region of interest (ROI). The visibility of interface between bone-prostheses was also estimated.Result of qualitative analysis indicated that score of CT quality was improved and grade of metal artifact was decreased significantly with O-Mar. Quantitative analysis illustrated that volume of beam-hardening (B-H) metal artifact decreased remarkably after reconstruction of O-Mar (Pâ<â.001). In addition, O-Mar algorithm reduced 83.3% to 83.7% volume of photon-starvation (P-S) metal artifact. As for result of 2D measurement, CT value in ROI was closer to standard value in O-Mar group CT image (Pâ<â.001). Meanwhile, error of CT value also decreased significantly after reconstruction of O-Mar algorithm. Visibility rate of bone-prosthesis interface improved from 34.3% (Non-O-Mar) to 66.7% (O-Mar).O-Mar algorithm could significantly reduce metal artifact in CT image of THA and TKA in both 2D and three-dimensional (3D) level. Therefore, better image quality and visibility of bone-prostheses interface could be presented. In this study, O-Mar was proved as an efficient metal artifact reduction method in CT image of THA and TKA.
Algorithms , Arthroplasty, Replacement, Hip/methods , Arthroplasty, Replacement, Knee/methods , Artifacts , Radiographic Image Enhancement/methods , Tomography, X-Ray Computed/methods , Adult , Aged , Cohort Studies , Female , Humans , Knee Prosthesis , Male , Metals , Middle Aged , Orthopedics , Retrospective Studies
Tibial component of total knee arthroplasty (TKA) is designed according to morphology of proximal tibia to a large extent. Owing to racial difference, current design of tibial component based on Caucasian may not be suitable for Chinese patients. Meanwhile, data of proximal tibial morphology in Chinese population is lacking. The objective of this research was to investigate proximal tibial morphology of northeast Chinese population.Computer tomography (CT) image of 164 northeast Chinese participants was collected. After three-dimensional (3D) reconstruction, size of tibia plateau and TKA resected surface were gauged to guide the design of TKA tibia prothesis in northeast Chinese population. Measurement of tibial size mainly includes tibial mediolateral length (tML), tibial medial/lateral anteroposterior length (tMAP and tLAP). Afterwards, tML/tAP ratio of tibia plateau and TKA resected surface were calculated as feature point of tibia prothesis. tMAP/tLAP ratio of TKA resected surface was calculated to represent tibial asymmetry degree. Medial and lateral posterior tibial slope (MPTS and LPTS) were also measured to give reference to posterior angle of tibia prothesis and angle of tibia osteotomy in TKA. Independent sample t test was performed to conduct statistical analysis, Pâ<â.05 was regarded as statistically significance.Northeast Chinese male has larger knee size than female. Significant difference of tML/tAP ratio was also observed between male and female on tibia plateau (1.71â±â0.07 vs 1.77â±â0.09) but not on TKA resected surface (1.60â±â0.05 versus 1.61â±â0.06). Significant difference of tMAP/tLAP ratio between male and female was also found and they were 1.31â±â1.03 and 1.11â±â0.05 respectively. Northeast Chinese female has higher PTS than male (MPTS: 9.56â±â2.96° vs 8.81â±â2.87° and LPTS: 8.57â±â3.19° vs 8.44â±â2.76°).Significant gender-difference of tibial size and asymmetry degree of tibial resected surface were found between northeast Chinese male and female. Meanwhile, northeast Chinese population has smaller knee size, larger PTS and tML/tAP ratio than that of Caucasian population. Therefore, Chinese-specific and gender-specific tibial prostheses were strongly recommended to be designed.
Arthroplasty, Replacement, Knee/methods , Image Interpretation, Computer-Assisted/methods , Tibia/diagnostic imaging , Tibia/surgery , Adult , China , Female , Humans , Imaging, Three-Dimensional , Male , Osteotomy , Tomography, X-Ray Computed , Young Adult
Conventional methods have limitations in measuring femoral neck torsion angle (FNTA) of patients with femoral deformities. A new method of three-dimensional (3D) reconstruction technology based on computer tomography (CT) was proposed to enhance measurement accuracy and applicability in this study.Bilateral FNTA of 50 developmental dysplasia of the hip (DDH) patients (DDH group) and 81 volunteers (normal group) were measured by Mimics software based on CT data with the marker lines determined by centerline and curvature. Each FNTA was measured by observer A and observer B for twice separately. 50 DDH patients were classified into 3 groups (group I, II, III) according to Hartofilakidis classification. The statistical analysis of the differences was made among the measurements of the FNTA.The FNTA values were 27.56°â±â12.48° in DDH group and 21.22°â±â8.14° in normal group with significant difference (tâ=â4.516, Pâ<â.001). The FNTA values were 24.53°â±â2.40° in group I, 29.78°â±â1.83° in group II and 39.08°â±â3.13° in group III, with significant difference (Fâ=â7.568, Pâ=â.001).The accuracy, reliability and applicable scope of FNTA measurement can be improved by 3D reconstruction in clinical practice. The applicable scope of this method included normal people and patients with femoral deformities. The FNTA of DDH patients is significantly larger than normal volunteers with a positive correlation between the severity of classification. This study will also provide references for preoperative design of Chinese population.
Femur Neck/anatomy & histology , Femur Neck/physiology , Imaging, Three-Dimensional/methods , China , Female , Humans , Male , Observer Variation , Preoperative Period , Reproducibility of Results , Tomography, X-Ray Computed , Torsion, Mechanical
RATIONALE: Pelvic tumor had great impact on patients' quality of life. After tumor resection, how to accurately fill bone defect remained challenging for orthopedic surgeons. Due to lack of individual design, high incidence of prosthetic mismatching, and loosening were reported in pelvic reconstruction surgery with conventional modular prostheses. Nowadays, with rapid development of three-dimensional (3D) print technology, pelvic prostheses could be designed according to patients' own anatomy. The objective of this study was to describe the application of 3D printed customized hemi-pelvic prosthesis for patients with pelvic tumor. PATIENT CONCERNS: A 62-year-old female had developed severe right joint pain without obvious inducement from 5 months before she sought medical advice. Pain, swelling, and limited range of motion of right joint were founded during physical examination. DIAGNOSIS: The patients were diagnosed as "right acetabulum metastatic carcinoma" INTERVENTION:: 3D printed titanium alloy hemi-pelvic prosthesis was designed according the morphology of unaffected side hemi-pelvis and subsequently implanted in surgery to reconstruct the pelvis. 3D printed osteotomy guide and pelvic model were also manufactured and applied to improve accuracy of osteotomy and reduce operation time. X-Ray of pelvis, Harris score, musculoskeletal tumor society score (MSTS) and The MOS item short from health survey (SF-36) were recorded during the period of preoperation, 1, 3, 6, 12 months follow-up after operation. OUTCOMES: 3D printed hemi-pelvic prosthesis matched precisely with pelvis and implanted successfully. There was no sign of prosthetic loosening within 12 months' follow-up. No sign of peri-prosthetic infection from laboratory examination. Harris score, MSTS, and SF-36 were gradually increasing during follow-up period. LESSONS: Satisfactory effect of pelvic reconstruction could be achieved by 3D printed hemi-pelvic prostheses. It also provided a promising way to the treatment of pelvic tumor in similar cases.
Pelvic Neoplasms/surgery , Plastic Surgery Procedures/methods , Printing, Three-Dimensional , Prosthesis Design/methods , Female , Humans , Middle Aged , Neoplasm Metastasis , Pelvic Neoplasms/pathology , Prosthesis Implantation
RATIONALE: This paper describes the application of individual customized 3-dimensional (3D) printed macro-porous Ti6Al4âV shoulder prosthesis in the revision of total shoulder arthroplasty (TSA) for the patient with severe bone defects. PATIENT CONCERNS: A 47-year-old male had been under proximal humeral resection and TSA due to shoulder chondrosarcoma 6 years ago, but a second surgery to insert a new prosthesis was then performed because the prosthesis became loose 2 months ago leaving severe bone defects which conventional prosthesis was not suitable for revision of TSA. American Shoulder and Elbow Surgeons' Form (ASES), Neer and Constant-Murley score were 36, 39, and 39, respectively. DIAGNOSES: The patient was diagnosed with shoulder bone defects and restriction of the shoulder movement. INTERVENTIONS: 3D printed shoulder model and computer-aided design (CAD) were used for prosthesis design and surgical simulation. The novel 3D printed titanium alloy shoulder prosthesis was customized subsequently to be used in the revision of TSA. The patient was followed up regularly after surgery. The ASES, Neer Shoulder score and Constant-Murley Shoulder score were evaluated during pre-operation, post-operation, and follow-up. OUTCOMES: Prosthesis was successfully implanted to complete anatomic reconstruction intraoperatively. The scores of ASES, Neer, and Constant-Murley were gradually increased after the operation. According to the X-ray, the bone healed satisfactorily without change of prosthetic position at 3rd and 12th months after the operation. The function of shoulder could meet the requirements of daily activities. LESSONS: The application of customized 3D printed titanium alloy shoulder prosthesis in the revision of TSA achieves satisfactory results. It provides a novel method for the similar revision surgery with severe bone defects.
Arthroplasty, Replacement, Shoulder , Bone Neoplasms , Chondrosarcoma , Humerus , Prosthesis Failure , Reoperation , Titanium/therapeutic use , Alloys , Arthroplasty, Replacement, Shoulder/adverse effects , Arthroplasty, Replacement, Shoulder/instrumentation , Arthroplasty, Replacement, Shoulder/methods , Bone Neoplasms/pathology , Bone Neoplasms/surgery , Chondrosarcoma/pathology , Chondrosarcoma/surgery , Humans , Humerus/pathology , Humerus/surgery , Imaging, Three-Dimensional/methods , Male , Middle Aged , Patient-Specific Modeling , Printing, Three-Dimensional , Reoperation/instrumentation , Reoperation/methods , Shoulder Prosthesis/adverse effects , Treatment Outcome
Objective To investigate the association between time from hospital admission to intensive care unit (ICU) admission (door to ICU time) and hospital mortality in patients with sepsis. Methods This retrospective observational study included routinely collected healthcare data from patients with sepsis. The primary endpoint was hospital mortality, defined as the survival status at hospital discharge. Door to ICU time was calculated and included in a multivariable model to investigate its association with mortality. Results Data from 13 115 patients were included for analyses, comprising 10 309 survivors and 2 806 non-survivors. Door to ICU time was significantly longer for non-survivors than survivors (median, 43.0 h [interquartile range, 12.4, 91.3] versus 26.7 h [7.0, 74.2]). In the multivariable regression model, door to ICU time remained significantly associated with mortality (odds ratio [OR] 1.11, 95% confidence interval [CI] 1.006, 1.017) and there was a significant interaction between age and door to ICU time (OR 0.99, 95% CI 0.99, 1.00). Conclusion A shorter time from hospital door to ICU admission was shown to be independently associated with reduced hospital mortality in patients with severe sepsis and/or septic shock.
Critical Care/statistics & numerical data , Sepsis/mortality , Sepsis/therapy , Aged , Aged, 80 and over , Boston/epidemiology , Databases, Factual , Female , Hospital Mortality , Humans , Intensive Care Units/statistics & numerical data , Male , Middle Aged , Patient Admission/statistics & numerical data , Retrospective Studies , Sepsis/epidemiology , Shock, Septic/epidemiology , Shock, Septic/mortality , Shock, Septic/therapy , Survival Analysis , Time Factors
BACKGROUND: Antibiotics impregnated calcium phosphate cement (CPC) has emerged as a local treatment of osteomyelitis. However, there is no study investigating the optimal concentrations of vancomycin (VCM) included in CPC to obtain prolonged drug release (≥8 weeks) and also with enough compressive strength (>the normal cancellous bone, 11MPa) for osteomyelitis therapy. Therefore, we bring forward two questions: 1) Was antibiotic activity of the eluates correlated to the load of antibiotics within the cement? 2) Were the mechanical properties of CPC affected by VCM-loading? HYPOTHESIZED: There was an optimal concentrations of vancomycin (VCM) loaded in CPC which could provide sufficient effective antibacterial time (≥8 weeks) and enough compressive strength (>11MPa). MATERIALS AND METHODS: CPC specimens were obtained by incorporating different doses (weigh ratios of 0%, 5%, 10%, 15%, 20%, 25 and 30%) of injectable VCM into CPC. The antibacterial effect of released VCM solution against Staphylococcus aureus was assessed by inhibition ring assays. The physicochemical properties such as compressive strengths were characterized and compared among these specimens. RESULTS: Drug release profiles showed only 5 and 10% VCM-loaded CPC displayed a long enough drug release time (at least 8 weeks) and maintained the eluate concentrations (>4µg/mL) with effective antibacterial ability. The concentration of VCM in 10% group at 8th week was twice higher than 5% group. Compressive strength test showed that the proportional increase of VCM/CPC ratios resulted in a significant decrease of compressive strength (r=-0.906, p<0.001). CONCLUSION: 10% VCM-loaded CPC offered the optimal physicochemical properties and drug releasing profile and appears as the most suitable concentration for clinical use. LEVEL OF EVIDENCE: III.
Anti-Bacterial Agents/pharmacology , Bone Cements , Compressive Strength , Vancomycin/pharmacology , Bone Cements/chemistry , Calcium Phosphates , Delayed-Action Preparations , Drug Carriers/chemistry , In Vitro Techniques , Materials Testing , Microbial Sensitivity Tests , Osteomyelitis/therapy , Staphylococcus aureus/drug effects
The rapid emergence of antibiotic resistance in pathogenic microbes is becoming an imminent global public health problem. Local application of antibiotics might be a solution. In local application, materials need to act as the drug delivery system. The drug delivery system should be biodegradable and prolonged antibacterial effect should be provided to satisfy clinical demand. Hydrogel is a promising material for local antibacterial application. Hydrogel refers to a kind of biomaterial synthesized by a water-soluble natural polymer or a synthesized polymer, which turns into gel according to the change in different signals such as temperature, ionic strength, pH, ultraviolet exposure etc. Because of its high hydrophilicity, unique three-dimensional network, fine biocompatibility and cell adhesion, hydrogel is one of the suitable biomaterials for drug delivery in antimicrobial areas. In this review, studies from the past 5 years were reviewed, and several types of antimicrobial hydrogels according to different ingredients, different preparations, different antimicrobial mechanisms, different antimicrobial agents they contained and different applications, were summarized. The hydrogels loaded with metal nanoparticles as a potential method to solve antibiotic resistance were highlighted. Finally, future prospects of development and application of antimicrobial hydrogels are suggested.
Anti-Infective Agents/administration & dosage , Drug Delivery Systems/methods , Hydrogels/pharmacology , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/pharmacology , Anti-Infective Agents/pharmacology , Humans , Hydrogels/chemistry , Metal Nanoparticles/administration & dosage , Metal Nanoparticles/chemistry , Metal Nanoparticles/therapeutic use , Polymers/chemistry , Temperature
Recently, clinical application of 3D printed model was increasing. However, there was no systemic study for confirming the precision and reliability of 3D printed model. Some senior clinical doctors mistrusted its reliability in clinical application. The purpose of this study was to evaluate the precision and reliability of stereolithography appearance (SLA) 3D printed model.Some related parameters were selected to research the reliability of SLA 3D printed model. The computed tomography (CT) data of bone/prosthesis and model were collected and 3D reconstructed. Some anatomical parameters were measured and statistical analysis was performed; the intraclass correlation coefficient (ICC) was used to was used to evaluate the similarity between the model and real bone/prosthesis. the absolute difference (mm) and relative difference (%) were conducted. For prosthesis model, the 3-dimensional error was measured.There was no significant difference in the anatomical parameters except max height (MH) of long bone. All the ICCs were greater than 0.990. The maximum absolute and relative difference were 0.45âmm and 1.10%; The 3-dimensional error analysis showed that positive/minus distance were 0.273âmm/0.237âmm.The application of SLA 3D printed model in diagnosis and treatment process of complex orthopedic disease was reliable and precise.
Bone and Bones/diagnostic imaging , Image Processing, Computer-Assisted/methods , Imaging, Three-Dimensional/methods , Musculoskeletal Diseases , Orthopedic Procedures , Stereolithography , Adult , Aged , Bone and Bones/injuries , China , Computer Simulation , Dimensional Measurement Accuracy , Female , Humans , Male , Middle Aged , Musculoskeletal Diseases/diagnosis , Musculoskeletal Diseases/surgery , Orthopedic Procedures/instrumentation , Orthopedic Procedures/methods , Prosthesis Implantation/instrumentation , Prosthesis Implantation/methods , Reproducibility of Results
In this research, we acquired the length of the superior temporal sulcus, the shortest distance from the superior temporal sulcus to the temporal horn of the lateral ventricle, and the approach angle between the median sagittal plane and the shortest segment from the superior temporal sulcus to the temporal horn of the lateral ventricle measuring 98 specimens by magnetic resonance imaging volume rendering. At the same time, we preliminarily oriented the point of the superior temporal sulcus, which is closest to the temporal horn of the lateral ventricle, aimed at finding out the best entrance point of surgical approach through the superior temporal sulcus to the temporal horn of the lateral ventricle and reducing the damage to optic radiation as well as other nerve fibers during the operation. The results indicate that the point at the front side 3/5 of the superior temporal sulcus may be the ideal surgical approach entrance point, and there is no difference between 2 cerebral hemispheres (P < 0.05).
Lateral Ventricles/anatomy & histology , Temporal Lobe/anatomy & histology , Adolescent , Adult , Aged , Amygdala/anatomy & histology , Female , Hippocampus/anatomy & histology , Humans , Image Processing, Computer-Assisted/methods , Magnetic Resonance Imaging/methods , Middle Aged , Neurosurgical Procedures , Parietal Lobe/anatomy & histology , Young Adult
