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2.
Tsitologiia ; 42(2): 166-9, 2000.
Article Ru | MEDLINE | ID: mdl-10752121

A short (75-110 min) mild (39.5 degrees C) whole body hyperthermia of humans does not alter the absolute amount of peripheral lymphocytes immediately after heating, but significantly reduces their relative amount due to neutrophil increase. Body heating does not induce lymphocyte degeneration: their potential viability does not reduce. The total level of lymphocyte oxidative metabolism remains unaltered, while SDG and LDG activities are seen reduced and increased, respectively. Lymphocytes adapt to body heating by inducing thermotolerant state and activating anaerobic metabolism.


Fever/pathology , Lymphocytes/pathology , Adaptation, Biological , Fever/physiopathology , Humans , Lymphocyte Count , Lymphocytes/physiology , Time Factors
4.
Eksp Klin Farmakol ; 59(4): 31-3, 1996.
Article Ru | MEDLINE | ID: mdl-9026186

A study was done on the action of the low molecular peptide preparation isolated from cow ovaries by the acetic acid extraction, on the rat ovary function. It was revealed that this preparation: 1) does not possess the gonadotrophic activity; 2) enhances the sensitivity of immature rat ovaries to the human chorionic gonadotrophin; 3) increases the number of ovulating oocytes in neonatal androgenized rats in gonadotrophic stimulation of the ovary function; 4) does not influence the character and duration of the estrous cycle in intact adult rats.


Ovary/chemistry , Peptides/pharmacology , Reproduction/drug effects , Animals , Animals, Newborn , Cattle , Chorionic Gonadotropin/pharmacology , Dose-Response Relationship, Drug , Drug Interactions , Estrus/drug effects , Female , Peptides/isolation & purification , Rats , Sexual Maturation/drug effects , Testosterone/pharmacology
7.
Biull Eksp Biol Med ; 103(3): 352-4, 1987 Mar.
Article Ru | MEDLINE | ID: mdl-3828517

Estrous cycle, ovulation rate and gamete quality were studied in rats with superovulation induced on different days of the cycle. It was shown that the rat ovaries in estrous were most sensitive to the action of gonadotropins. Heterogeneity in the ovulation rate was noted in animals at the same phase of the cycle. There was a relative increase in the number of gametes with chromosomal alterations in experimental rats, with the value depending on the stage of the cycle when PMS was injected. The study of the estrous cycle in rats with superovulation induced on different days of the cycle has revealed strong hormonal influences on the sequence of stage alterations.


Estrus/drug effects , Gametogenesis/drug effects , Ovulation/drug effects , Superovulation/drug effects , Animals , Chromosome Aberrations , Female , Gonadotropins, Equine/pharmacology , Rats , Time Factors , Vaginal Smears
8.
Tsitologiia ; 28(11): 1259-61, 1986 Nov.
Article Ru | MEDLINE | ID: mdl-3564153

The ultrastructure of ovocytes, fixed no later than 4-5 hours after the beginning of ovulation, the number of cells with the signs of organelle alterations is increased. This is presumably connected with a change in conditions of hormonal regulation of late stages of gametogenesis.


Oocytes/ultrastructure , Ovulation Induction , Ovulation/drug effects , Superovulation/drug effects , Animals , Chorionic Gonadotropin/pharmacology , Female , Gonadotropins, Equine/pharmacology , Oocytes/drug effects , Rats , Time Factors
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