Clear cell carcinoma arising in an ovarian remnant 19 years after oophoerctomy: case report.

BACKGROUND: Ovarian remnant syndrome (ORS) is a rare complication that occurs after oophorectomy, characterized by residual ovarian tissue causing pelvic pain, masses, and various symptoms. The clinical manifestations of ORS are nonspecific, and its diagnosis relies on histological examination. Since ORS typically represents a benign ovarian lesion, there have been few reported cases of malignant transformation. In this report, we presented a unique case of ovarian clear cell carcinoma (OCCC) arising from an ovarian remnant following salpingo-oophorectomy. CASE PRESENTATION: Our patient was a 47-year-old female initially diagnosed with uterine myoma. She had previously undergone cesarean section and unilateral salpingo-oophorectomy. Transvaginal ultrasound and computed tomography (CT) scans revealed a soft tissue mass adjacent to the right lateral wall of the myometrium. The patient opted for transabdominal hysterectomy, left adnexal resection, laparoscopic omentectomy, appendectomy, and pelvic and abdominal lymphadenectomy. The final pathology results confirmed the diagnosis of OCCC, consistent with ORS. The patient subsequently received six cycles of intravenous chemotherapy using the carboplatin/paclitaxel (TC) regimen (paclitaxel liposomes 175 mg/m², carboplatin AUC 5). After 3 years of follow-up, the patient's condition remained normal. CONCLUSION: ORS can significantly impact patients' quality of life and pose challenges for clinicians. Complete excision of ovarian tissue during the initial surgery is crucial in preventing ORS recurrence and potential malignant transformation of ovarian remnants.

Significant winter CO2 uptake by saline lakes on the Qinghai-Tibet Plateau.

Direct measuring of CO2  flux remains challenging for global lakes. The traditional sampling and gas transfer models used to estimate lake CO2  fluxes are variable and uncertain, and ice-covered periods are often excluded from the annual carbon budget. Here, the first longtime (2013-2017) direct measurement of CO2  flux by eddy covariance system over the largest saline lake (Qinghai lake) in the Qinghai-Tibet Plateau (QTP) revealed that ice-covered period draws large amounts of CO2 from the atmosphere (-0.87 ± 0.38 g C m-2 d-1 ), a value more than twice the CO2  flux rate during the ice-free period (-0.41 ± 0.35 g C m-2 d-1 ). The total CO2 uptake by all saline lakes on the QTP was estimated to -10.28 ± 1.65 Tg C yr-1 , an equivalent to approximately one third of the net terrestrial ecosystems carbon sink in QTP. Our results indicate large sink for CO2 in winter is controlled by both seasonal hydrochemistry processes and lake ice absorption in saline lakes. This research also demonstrates decreasing CO2 uptake from the atmosphere by saline lakes on the QTP, which may turn carbon sinks to carbon sources with future warming.

Phytoestrogens for the Management of Endometriosis: Findings and Issues.

Endometriosis, a chronic disease characterized by recurrent pelvic pain and infertility, severely impacts the health and life quality of many women worldwide. Since phytoestrogens are commonly found in a variety of foods, and estrogen is a major pathological factor for the pathogenesis of endometriosis, their possible involvement cannot be ignored. This review summarizes data on the relationship between phytoestrogen intake and endometriosis risk, and analyzes the findings from in vitro experiments, rodent endometriotic models, and human intervention trials. While favorable results were often obtained from endometrial primary cultures and animal models for resveratrol, isoflavones and puerarin, only resveratrol showed promising results in human intervention trials. Critical issues concerning the current study efforts are discussed: the possible reasons beneath the discrepant observations of estrogenic/anti-estrogenic effects by phytoestrogens; the complicated interplays between phytoestrogens and endogenous estrogens; the shortage of currently used animal models; the necessity to apply reasonable doses of phytoestrogens in experiments. It is expected that the analyses would help to more properly assess the phytoestrogens' effects on the endometriosis pathogenesis and their potential values for preventive or therapeutic applications.

[Atmospheric Influences Analysis on the Satellite Passive Microwave Remote Sensing].

Passive microwave remote sensing offers its all-weather work capabilities, but atmospheric influences on satellite microwave brightness temperature were different under different atmospheric conditions and environments. In order to clarify atmospheric influences on Advanced Microwave Scanning Radiometer-Earth Observing System (AMSR-E), atmospheric radiation were simulated based on AMSR-E configuration under clear sky and cloudy conditions, by using radiative transfer model and atmospheric conditions data. Results showed that atmospheric water vapor was the major factor for atmospheric radiation under clear sky condition. Atmospheric transmittances were almost above 0.98 at AMSR-E's low frequencies (< 18.7 GHz) and the microwave brightness temperature changes caused by atmosphere can be ignored in clear sky condition. Atmospheric transmittances at 36.5 and 89 GHz were 0.896 and 0.756 respectively. The effects of atmospheric water vapor needed to be corrected when using microwave high-frequency channels to inverse land surface parameters in clear sky condition. But under cloud cover or cloudy conditions, cloud liquid water was the key factor to cause atmospheric radiation. When sky was covered by typical stratus cloud, atmospheric transmittances at 10.7, 18.7 and 36.5 GHz were 0.942, 0.828 and 0.605 respectively. Comparing with the clear sky condition, the down-welling atmospheric radiation caused by cloud liquid water increased up to 75.365 K at 36.5 GHz. It showed that the atmospheric correction under different clouds covered condition was the primary work to improve the accuracy of land surface parameters inversion of passive microwave remote sensing. The results also provided the basis for microwave atmospheric correction algorithm development. Finally, the atmospheric sounding data was utilized to calculate the atmospheric transmittance of Hailaer Region, Inner Mongolia province, in July 2013. The results indicated that atmospheric transmittances were close to 1 at C-band and X-band. 89 GHz was greatly influenced by water vapor and its atmospheric transmittance was not more than 0.7. Atmospheric transmittances in Hailaer Region had a relatively stable value in summer, but had about 0.1 fluctuations with the local water vapor changes.