RESUMEN
Synchronization and frequency locking between remote mechanical oscillators are of scientific and technological importance. The key challenges are to align the oscillation frequencies and realize strong nonlinear interaction of both oscillators to a common carrier capable of long-distance transmission. Here, we experimentally realize the all-optical synchronization between two different optomechanical systems, a microsphere and a microdisk. The mechanical oscillation of the microsphere induced by the radiation pressure is loaded onto the pump laser via the optomechanical interaction, which is directly transmitted through a 5-km-long single-mode fiber to excite the mechanical oscillation of the microdisk. By finely tuning both the optical and mechanical frequencies of the two microresonators, the oscillation of the microdisk is injection locked to the microsphere, resulting in a synchronized phase relation of the two systems. Our results push a step forward the long-distance synchronization network using optomechanical microresonators.
RESUMEN
A tunable Raman laser in the hollow bottle-like microresonator is demonstrated. By controlling the pump laser frequency, we have demonstrated continuous Raman laser frequency tuning. We also have studied the interesting transient mode evolution with Raman gain by sweeping the pump and probe laser, and verified the thermal tuning mechanism by theoretical simulations. By mechanically stretching the resonator, we have achieved the large range frequency tuning of the Raman laser, with the tuning range of 132 GHz with the resolution about 85 MHz. The demonstrated tunable Raman laser can be used as a source for future optical applications.
RESUMEN
In this paper, we report the mechanical tuning of the optical and mechanical modes in the hollow bottle-like microresonator (BLMR). The optical modes with a quality factor of 1.55 × 108 and mechanical modes with a quality factor of 2.5 × 103 were demonstrated in such microresonators. By stretching the microresonator, the optical modes can be tuned over one free spectral range, as large as 917 GHz (~ 7.3 nm). Meanwhile, the range of frequency tuning of mechanical modes can be as large as 1 MHz, which is about 2.9% of the mode frequency. This effective approach to tune the optomechanical cavity can be used for the tunable photon-phonon conversion and the synchronization of mechanical oscillators in separated optomechanical systems.
RESUMEN
OBJECTIVE: To investigate the clinical efficacy and safety of "3+7" regimen and decitabine + HAG pre-excitation regimen in the treatment of elderly MDS patients with AML transformed by abnormal proliferation of bone marrow. METHODS: Fifty elderly patients with AML transformed by abnormal proliferation of bone marrow in the period from March 2012 to May 2014 were chosen and randomly divided into 2 groups including A group (25 elderly patients treated with "3+7" regimen) and B group (25 elderly patients treated with decitabine+HAG pre-excitation regimen), and the clinical effeicacy, the median survival time and the incidence of drug adverse effects in 2 groups were compared. RESULTS: The clinical total remission rate in B group was significantly higher than that in A group(P<0.05). The leukopenia time, neutropenia time and recovery time of leukocyte and neutrophilia in B group were significantly shorter than those in A group, the differences were statistically significant (P<0.05). The rate of lung infection in B group was significantly lower than that in A group. There was no significant difference in the incidence of other drug adverse effects between 2 groups(P>0.05). The life quality of patients in B group was significantly prior to patients in A group, and the difference was statistically significant (P<0.05). The average survival time and the median survival time of patients in B group was significantly longer than those in A group(P<0.05). CONCLUSION: Compared with "3+7" regimen, the decitabine+HAG pre-excitation regimen in the treatment of elderly patients with AML transformed by abnormal proliferation of bone marrow can efficiently delay the disease progression process, shorten the time of bone marrow suppression, decrease the rate of lung infection and prolong the survival time.
