RESUMEN
Fibromyalgia (FM) is a pain syndrome with a high burden and an understudied etiology and pathogenesis. There is now considerable evidence that FM has a strong bidirectional relationship with psychiatric disorders and is associated with certain personality traits that contribute to the severity of key somatic symptoms and affect overall prognosis. In this article, the authors present data from recent epidemiological and neurobiological studies, discuss the multilevel relationship between FM and psychiatric disorders, and briefly review approaches to the treatment of co-morbid conditions.
Asunto(s)
Fibromialgia , Trastornos Mentales , Humanos , Fibromialgia/epidemiología , Trastornos Mentales/epidemiología , Trastornos Mentales/etiología , Trastornos SomatomorfosRESUMEN
Autonomic dysfunction is frequently observed in people with epilepsy. Ictal and postictal dysautonomia is not only manifestation of autonomic seizures, but could be a life threatening condition in some cases and contribute to sudden unexpected death (SUDEP). Interictal decrease of autonomic activity is associated with duration and severity of epilepsy, it is the most prominent in focal and drug-resistant epilepsy. Progress in our understanding of the underlying mechanisms, development of the autonomic assessment methods, and its integration in novel technical solutions for seizure detection will improve the quality of care for people with epilepsy.
Asunto(s)
Epilepsia , Disautonomías Primarias , Muerte Súbita e Inesperada en la Epilepsia , Muerte Súbita/etiología , Electroencefalografía/métodos , Epilepsia/complicaciones , Humanos , Disautonomías Primarias/complicaciones , Disautonomías Primarias/etiología , Convulsiones/complicacionesRESUMEN
Problems of synthesis of devices for detection of medico-biological parameters are considered. A classification of the devices and their functional units is proposed. An algorithm for synthesis of detectors of medico-biological parameters on the basis of multiple-use functional units is suggested. The algorithm is based on analysis of functional unit modifications providing optimization of the device characteristics.