Effects of nutrition education given to persons with multiple sclerosis and their families on diet quality and anthropometric and biochemical measurements / Efeito da educação nutricional dada a pessoas com esclerose múltipla e suas famílias em relação a qualidade da dieta, medidas antropométricas e bioquímicas

ABSTRACT Objective: In this study, it was aimed to investigate the effects of nutrition education given to persons with multiple sclerosis and their families on anthropometric and biochemical measurements and diet quality. Methods: Data from 51 persons with multiple sclerosis were analysed in this intervention study. The study was conducted with 3 groups. The education group consisted of only persons with multiple sclerosis, the family education group consisted of persons with multiple sclerosis and a family member living with them, and the control group consisted of persons with multiple sclerosis who had not received an education. Anthropometric and biochemical measurements and dietary quality assessments were made before (T1) and immediately after education (T2) and also 3 months after education (follow-up, T3). Results: The distribution of family education group diet quality scores showed a significant increase from "poor" to "needs improvement" at T3 compared to T1. The upper middle arm circumference measurements of the female control group were decreased at T2 and T3 [from 29.0 (23-34) cm to 28.0 (22-31) cm and to 27.5 (22-31) cm]. Women in family education group, levels of serum haemoglobin and haematocrit were higher than in control group at T2 and T3. Also, men in family education group, levels of alanine aminotransferase were lower than those in education group at follow up. Levels of total cholesterol and low-density lipoprotein cholesterol in education group were higher than those control group at T1, T2, and T3. Conclusion: This study indicates that nutrition education affects some biochemical and anthropometric measurements in persons with multiple sclerosis. Diet quality improved when receiving education together with families.

RESUMO Objetivo: Objetivou-se investigar os efeitos da educação nutricional dada a pessoas com esclerose múltipla e seus familiares, avaliação de medidas antropométricas, bioquímicas e da qualidade da dieta. Métodos: Dados de 51 participantes com esclerose múltipla foram analisados neste estudo de intervenção. O estudo foi dividido em 3 grupos, sendo o primeiro composto por indivíduos que obtiveram educação nutricional, o segundo, composto por indivíduos mais um membro da família que morava com eles e obtiveram educação nutricional, e o terceiro, grupo controle, composto por indivíduos que não obtiveram educação nutricional. Medidas antropométricas, bioquímicas e avaliações da qualidade da dieta foram feitas antes (T1) imediatamente após a educação nutricional (T2) e também 3 meses após a educação nutricional (T3). Resultados: A distribuição dos escores de qualidade da dieta do grupo de educação familiar mostrou um aumento significativo de "ruim" para "precisa melhorar" no T3 em comparação ao T1. As medidas da circunferência do braço médio do grupo controle feminino foram menores em T2 e T3 [de 29,0 (23-34) cm para 28,0 (22-31) cm e para 27,5 (22-31) cm]. Nas mulheres do grupo família, os níveis séricos de hemoglobina e hematocrito foram maiores do que no grupo controle em T2 e T3. Também nos homens do grupo família, os níveis de alanina aminotransferasa foram mais baixos do que os do grupo educação no seguimento. Os níveis de CT e LDL-C no grupo educação foram superiores aos do grupo controle em T1, T2 e T3. Conclusão: Este estudo observou que a educação nutricional afeta algumas medidas bioquímicas antropométricas em pessoas com esclerose múltipla. A qualidade da dieta melhorou quando recebeu educação junto com as famílias.

Consumption of ultra-processed foods and anthropometric indicators in adolescents, adults, and the elderly in a capital city in northeastern Brazil / Consumo de alimentos ultraprocessados e indicadores antropométricos em adolescentes, adultos e idosos de uma capital do Nordeste do Brasil

ABSTRACT Objective To evaluate the consumption of ultra-processed foods and associate it with anthropometric indicators in adolescents, adults, and the elderly. Methods Cross-sectional, domiciliary, population-based study, comprising adolescents aged 10-19 years, adults aged 20-59 years, and elderly people aged 60 or older, residents of the urban area of the city of Teresina, Piauí. Demographic, socioeconomic, lifestyle, food consumption, and anthropometric data were collected. The analysis of variance test was used along with the Bonferroni post-hoc test and crude and adjusted linear regression with a 95% confidence interval (95% CI). The level of significance adopted was 5%. Results There was no significant association between the consumption of ultra-processed foods and anthropometric variables in adults and the elderly. However, among adolescents, the results showed an inverse association, thus signaling a reduction in anthropometric indicators as the consumption of ultra-processed foods increases. Conclusion There was no association between the consumption of ultra-processed foods and anthropometric indicators in adults and the elderly; however, among adolescents, the results showed an inverse association, which encourages the development of new studies, especially longitudinal ones.

RESUMO Objetivo Avaliar o consumo de alimentos ultraprocessados e associá-lo a indicadores antropométricos em adolescentes, adultos e idosos Métodos Estudo transversal, domiciliar, de base populacional, compreendendo adolescentes de 10-19 anos, adultos de 2059 anos e idosos de 60 anos ou mais, residentes na zona urbana da cidade de Teresina, Piauí. Foram coletados dados demográficos, socioeconômicos, de estilo de vida, consumo alimentar e antropométrico. O teste de análise de variância foi utilizado juntamente com o teste post-hoc de Bonferroni e regressão linear bruta e ajustada com intervalo de confiança de 95% (IC95%). O nível de significância adotado foi de 5%. Resultados Não houve associação significativa entre o consumo de alimentos ultraprocessados e indicadores antropométricos em adultos e idosos, entretanto, entre os adolescentes, os resultados demonstraram uma associação inversa, sinalizando redução dos indicadores antropométricos à medida que se aumenta o consumo de ultraprocessados. Conclusão Não houve associação entre o consumo de alimentos ultraprocessados e indicadores antropométricos em adultos e idosos, entretanto, entre os adolescentes, os resultados demonstraram uma associação inversa, o que incentiva o desenvolvimento de novos estudos, especialmente, longitudinais.

¿Cómo se pesa al paciente con trastorno de la conducta alimentaria? Revisión del abordaje del peso en los tratamientos / How is the patient with Eating Disorders weighed? Review of weight approach in treatments

Introducción: la excesiva preocupación por el peso y la forma corporal en los Trastornos de la Conducta Alimentaria (TCA) conducen a conductas obsesivas de chequeo y/o evitación corporal. Existe consenso que el peso es un elemento fundamental en el tratamiento de los TCA, sin embargo, en el pesaje conviven enfoques múltiples. Objetivo: describir cómo se aborda el pesaje en el tratamiento de los pacientes con TCA. Materiales y método: el estudio consiste en una revisión de bibliografía, descriptiva. Se incluyeron publicaciones científicas mediante la búsqueda actualizada en base de datos: Scielo, Lilacs y Pubmed, desde 2010 hasta el 2020. Los descriptores de la búsqueda fueron: "pesaje y trastornos alimentarios/desórdenes alimentarios" y "tratamiento, trastornos alimentarios y pesaje". Resultados: de la búsqueda bibliográfica quedaron incluidos 14 artículos internacionales de diseño descriptivo. Los estudios fueron diversos, en estudiantes, atletas, pacientes, grupo control y profesionales, el tamaño muestral fue desde 24 instituciones especializadas en TCA hasta una población de 2287 participantes. Ningún estudio identificó cuál es el profesional encargado de pesar al paciente. El 75% de los artículos que describieron la modalidad de pesaje eligieron pesaje ciego en el comienzo del tratamiento y el resto optó por pesaje abierto, utilizándolo como terapia de exposición. Todos los profesionales modificaron la modalidad de pesaje según el nivel de ansiedad del paciente y el tiempo del tratamiento. Los pacientes prefirieron el pesaje ciego como beneficioso para sus tratamientos. El 90% de los estudios mostraron que los individuos que se autopesaban con mayor frecuencia, iniciaron más tempranamente atracones y conductas compensatorias. Conclusión: los tratamientos basados en evidencia no abordan la modalidad del pesaje de manera consensuada y las recomendaciones varían dentro de las terapias, y a lo largo del tiempo. La utilidad terapéutica del pesaje en los TCA es fundamental para evaluar el riesgo, alertar sobre los cambios en la ingesta alimentaria y para reducir la ansiedad. Sin embargo, es necesario abordarlo con profesionalismo e interdisciplina para disminuir el impacto sobre las conductas perjudiciales para la salud y la psicopatología. Se recomiendan más estudios que ayuden a construir criterios comunes y guías de consenso regional para mejorar el tratamiento de los TCA(AU).

Introduction: excessive concern about weight and body shape in Eating Disorders (ED) lead to obsessive checking and/or body avoidance behaviors. There is consensus that weight is a fundamental element in the treatment of eating disorders, however multiple approaches coexist in weighing. Objectives: to describe how weighing is addressed in the treatment of patients with ED Materials and method: the study consists of a descriptive bibliographic review. Scientific publications were included through the updated database search: Scielo, Lilacs and Pubmed, from 2010 to 2020. Search descriptors were: "body weight and eating disorders/eating disorders" and "treatment, eating disorders and body weight". Results: out of the bibliographic search, 14 international articles of descriptive design were included. The sample groups of the studies were diverse, including students, athletes, patients, control group and professionals, with a sample size of 2287 participants and 24 institutions specialized in eating disorders. No study identified the professional in charge of weighing the patient. 75% of the articles that described the weighing modality chose blind weighing at the beginning of the treatment and the rest opted for open weighing, using it as exposure therapy. All the professionals modified the weighing modality according to the patient's anxiety level and the treatment time. Patients preferred blind weighing as beneficial for their treatment. 90% of the studies showed that individuals who self-weighed more frequently initiated binge eating and compensatory behaviors earlier. Conclusion: evidence-based treatments do not consensually address how the patient is weighed, and the recommendations vary according to therapies and time period. The therapeutic utility of ED weighing is essential to assess risk, alert to changes in food intake, and to reduce anxiety. However, it is necessary to approach it with professionalism and interdiscipline to reduce the impact on behaviors harmful to health and psychopathology. More studies are recommended to help build common criteria and regional consensus guidelines to improve the treatment of ED(AU).

Comparação de métodos de avaliação corpórea de cães da raça labrador e teckel / Comparison of body assessment methods for labrador and teckel dogs / Comparación de métodos de evaluación corporal para perros labrador y teckel

Uma nutrição apropriada é um dos pré-requisitos mais importantes para a saúde e bem-estar animal, e a manutenção do peso ideal pode prevenir inúmeras doenças. Diferentes métodos de avaliação da condição corpórea vêm sendo empregados na medicina veterinária. Apesar da alta reprodutibilidade do escore de condição corpórea (ECC), ainda existem preocupações sobre subjetividade e precisão, e os métodos morfológicos, como o índice de massa corporal canina (IMCC), aparecem como uma alternativa para essa desvantagem, por ser um método quantitativo. O estudo avaliou o IMCC de 50 cães, 30 da raça labrador e 20 da raça teckel e comparou com os ECCs. Informações sobre características dos animais, hábito alimentar e tipo de manejo, também foram analisados quanto à condição corpórea apresentada. A comparação entre os métodos de ECC e IMCC apresentou discrepância de classificação em um elevado número de animais, a característica da morfologia corporal dos cães pode interferir com sua precisão.(AU)

Proper nutrition is one of the most important prerequisites for animal health and welfare, and dogs optimal weight maintenance can prevent numerous diseases. Different methods of corporeal condition evaluation have been used in veterinary medicine. Although widely used, the body condition score (BCS) is a test influenced by the evaluator experience and a quantitative method, such as the dog body mass index (IMCC), appears as an alternative to this disadvantage. However, the large variation in the body morphology dogs can interfere with their accuracy. The study evaluated 50 dogs IMCC, 30 Labrador breed and 20 Dachshund breed and compared with the animals ECC. Information on animal characteristics, eating habits and type of management were also analyzed for the body condition presented. The comparison between the ECC and IMCC methods showed a classification discrepancy in a high number of animals, the characteristic of the dogs' body morphology can interfere with its accuracy.(AU)

Una nutrición adecuada es uno de los requisitos previos más importantes para la salud y el bienestar de los animales, y el mantenimiento del peso ideal del perro puede prevenir numerosas enfermedades. En medicina veterinaria se han utilizado diferentes métodos para evaluar la condición corporal. Aunque ampliamente utilizado, la puntuación de la condición corporal (PCC) es una prueba influenciada por la experiencia del evaluador y los métodos cuantitativos, como el índice de masa corporal canina (IMCC), aparecen como una alternativa a esta desventaja. Sin embargo, la gran variación en la morfología corporal de los perros puede interferir con su precisión. El estudio evaluó el IMCC de 50 animales, 30 de la raza labrador y 20 de la raza teckel y lo comparó con los ECC. También se analizó la información sobre las características de los animales, los hábitos de alimentación y el tipo de manejo para determinar la condición corporal. La comparación entre los métodos ECC e IMCC mostró una discrepancia de clasificación en un alto número de animales, la característica de la morfología corporal de los perros puede interferir con su precisión.(AU)

Comparação de métodos de avaliação corpórea de cães da raça labrador e teckel / Comparison of body assessment methods for labrador and teckel dogs / Comparación de métodos de evaluación corporal para perros labrador y teckel

Uma nutrição apropriada é um dos pré-requisitos mais importantes para a saúde e bem-estar animal, e a manutenção do peso ideal pode prevenir inúmeras doenças. Diferentes métodos de avaliação da condição corpórea vêm sendo empregados na medicina veterinária. Apesar da alta reprodutibilidade do escore de condição corpórea (ECC), ainda existem preocupações sobre subjetividade e precisão, e os métodos morfológicos, como o índice de massa corporal canina (IMCC), aparecem como uma alternativa para essa desvantagem, por ser um método quantitativo. O estudo avaliou o IMCC de 50 cães, 30 da raça labrador e 20 da raça teckel e comparou com os ECCs. Informações sobre características dos animais, hábito alimentar e tipo de manejo, também foram analisados quanto à condição corpórea apresentada. A comparação entre os métodos de ECC e IMCC apresentou discrepância de classificação em um elevado número de animais, a característica da morfologia corporal dos cães pode interferir com sua precisão.

Proper nutrition is one of the most important prerequisites for animal health and welfare, and dogs optimal weight maintenance can prevent numerous diseases. Different methods of corporeal condition evaluation have been used in veterinary medicine. Although widely used, the body condition score (BCS) is a test influenced by the evaluator experience and a quantitative method, such as the dog body mass index (IMCC), appears as an alternative to this disadvantage. However, the large variation in the body morphology dogs can interfere with their accuracy. The study evaluated 50 dogs IMCC, 30 Labrador breed and 20 Dachshund breed and compared with the animals ECC. Information on animal characteristics, eating habits and type of management were also analyzed for the body condition presented. The comparison between the ECC and IMCC methods showed a classification discrepancy in a high number of animals, the characteristic of the dogs' body morphology can interfere with its accuracy.

Una nutrición adecuada es uno de los requisitos previos más importantes para la salud y el bienestar de los animales, y el mantenimiento del peso ideal del perro puede prevenir numerosas enfermedades. En medicina veterinaria se han utilizado diferentes métodos para evaluar la condición corporal. Aunque ampliamente utilizado, la puntuación de la condición corporal (PCC) es una prueba influenciada por la experiencia del evaluador y los métodos cuantitativos, como el índice de masa corporal canina (IMCC), aparecen como una alternativa a esta desventaja. Sin embargo, la gran variación en la morfología corporal de los perros puede interferir con su precisión. El estudio evaluó el IMCC de 50 animales, 30 de la raza labrador y 20 de la raza teckel y lo comparó con los ECC. También se analizó la información sobre las características de los animales, los hábitos de alimentación y el tipo de manejo para determinar la condición corporal. La comparación entre los métodos ECC e IMCC mostró una discrepancia de clasificación en un alto número de animales, la característica de la morfología corporal de los perros puede interferir con su precisión.

Scutation asymmetries in red-footed tortoise Chelonoidis carbonaria Spix, 1824 (Testudines: Testudinidae)

The ability of an individual to withstand random perturbations during its development is considered a good indicator of environmental and genetic stress. A common means of assessing developmental stability is through analysis of fluctuating asymmetry (FA) in bilateral traits. Tortoises, with their large, solid plastron, allow for measurement of body geometry. Their bilateral shell scutes are ideal candidates for asymmetries researches. With this issue in mind we assessed, as a preliminary study, levels of plastron scute asymmetry in a sample of 46 red-footed tortoise Chelonoidis carbonaria from Arauca, N Colombia. We found significative fluctuating asymmetry (FA) but no directional asymmetry, the former not increasing with carapace size and thus indicating that tortoise shells do not become increasingly asymmetrical with age, or in other words, signaling that FA is not being influenced by pholidosis (variability of scale cover mosaic according to the development of the scutes). Asymmetry in plastron shape, although not necessarily apparent at first glance, varied, with gender with males exhibiting higher levels of FA than females. Although we can not identify the potential sources of variation responsible for the observed patterns of developmental instability, we consider this detected form of asymmetry due to unfavorable environmental conditions.(AU)

Escore visual como uma ferramenta eficiente para identificação de bovinos precoces / Visual scores are an efficient tool for identifying precocious cattle

A hipótese testada foi a possibilidade de identificar animais que depositam gordura e músculo mais precocemente através de avaliação indireta. Assim, o objetivo desse trabalho foi verificar a possibilidade da utilização da avaliação visual de escore de precocidade na identificação de novilhas Nelore com biotipo precoce. Foram avaliadas visualmente, 18 novilhas Nelore com idade de 9 a 11 meses, por escores para estrutura corporal (E), precocidade (P) e musculosidade (M). Os animais foram separados conforme os escores de precocidade, 4, 5 e 6 foram considerados com o biotipo precoce e 1, 2 e 3 foram classificados como biotipo tardio. Tomaram-se as medidas de área de olho de lombo (AOL) e espessura de gordura subcutânea (EGS) e na picanha (EGP) por ultrassonografia. Os animais classificados como precoce receberam maiores (P ≤ 0,05) escores para E (5,1 vs 2,4) e M (4,4 vs 2,6), o que resultou em animais mais pesados (233,2 vs 202,8 kg). Não foi observado efeito (P ≥ 0,05) do biotipo para a AOL (36,5 cm2), porém, animais classificados como precoce apresentaram maior (P ≤ 0,05) EGS (1,3 vs 0,5 cm) e EGP (2,9 vs 2,3 cm). Os coeficientes canônicos padronizados revelaram que a EGP (0,78) e o escore M (-1,02) são as variáveis que mais interferem sobre a primeira variável canônica de forma positiva e negativa, respectivamente. A variação total das características avaliadas foi explicada em 100% pela primeira variável canônica. O escore de precocidade mostrou ser uma alternativa eficiente para identificação de indivíduos precoces. A diferenciação de animais com biotipo precoce foi melhor elucidada pela espessura de gordura na picanha e pelo desenvolvimento muscular do animal.(AU)

The hypothesis tested was that it is possible to identify animals that deposit fat and muscle earlier through indirect evaluation. Thus, the objective of this work was to evaluate the use of visual evaluation of precocity score for the identification of Nelore heifers with an early biotype. Eighteen Nelore heifers aged 9 to 11 months were evaluated visually for body structure (S), precocity (P), and muscle (M) scores. The animals were divided according to precocity scores: animals with scores 4, 5 and 6 were classified as early biotype and those with scores 1, 2 and 3 as late biotype. Loin eye area (LEA) and subcutaneous (SFT) and picanha (biceps femoris muscle) fat thickness (PFT) were measured by ultrasonography. Animals classified as precocious received higher scores (P≤0.05) for S (5.1 vs 2.4) and M (4.4 vs 2.6), which resulted in heavier animals (233.2 vs 202.8 kg). No biotype effect (P≥0.05) was observed for LEA (36.5 cm2), but animals classified as precocious had higher (P≤0.05) SFT (1.3 vs 0.5 cm) and PFT (2.9 vs 2.3 cm). The standardized canonical coefficients showed that PFT (0.78) and the M (-1.02) score are the variables that most affect the first canonical variable positively and negatively, respectively. The first canonical variable explained 100% of the total variation in the traits evaluated. The precocity score was found to be an efficient alternative for the identification of precocious individuals. Animals with an early biotype were better differentiated by fat thickness in the biceps femoris and by muscle development of the animal.(AU)

Reprodutibilidade e repetibilidade de mensuração radiográfica da silhueta cardíaca em cães da raça poodle / Reproducibility and repeatability of radiographic measurement of the cardiac silhouette in poodles

Avaliou-se o potencial de reprodutibilidade e repetibilidade de um sistema semiautomático de mensuração radiográfica. Para isto foram mensurados, por intermédio de um software o vertebral heart score (VHS) e a área cardíaca normalizada (ACN) em imagens radiográficas de cães da raça poodle clinicamente normais e portadores de insuficiência valvar mitral. Dada a subjetividade da análise da silhueta cardíaca por diferentes observadores, acredita-se que mesmo com um sistema semiautomático essa avaliação poderia ser afetada pela experiência prévia do observador em radiodiagnóstico. Foram analisadas cinquenta e sete imagens radiográficas torácicas de cães atendidos em um hospital veterinário. As imagens foram analisadas por dois grupos de observadores com diferentes níveis de experiência em radiologia: (A) sem experiência (n = 2) e (B) com experiência (n = 2). Demonstrou-se boa repetibilidade e reprodutibilidade para o VHS independente da experiência em radiodiagnóstico, e para a ACN em observadores experientes e com familiaridade com o software.(AU)

The potential of reproducibility and repeatability of a semi-automatic system of radiographic measurement was evaluated. For this purpose, the vertebral heart score (VHS) and normalized cardiac area (NCA) were evaluated in radiographs of healthy poodles and of patients with mitral regurgitation. Considering the subjective aspect of the cardiac silhouette analysis by different observers, it is believed that even with a semi-automatic system this evaluation could be affected by the previous experience of the observer in radiodiagnosis. Fifty seven thoracic images were analyzed by two groups of observers with different levels of experience in radiology: (A) without experience (n = 2) and (B) with experience (n = 2). Regardless of radiodiagnostic experience it was observed good repeatability and reproducibility for VHS, and also for ACN in observers with experience in radiodiagnostics and previous familiarity with the software.(AU)

Nonlinear mixed effects models for comparing growth curves for Guzerá cattle / Modelos não lineares mistos para comparar curvas de crescimento de bovinos da raça Guzerá

The objective of the present work was to evaluate the accuracy of the fitted Gompertz and von Bertalanffy models for male and female Guzerá cattle, respectively. Four production regions in Northeast Brazil were included in the models as a fixed effect, and the animals were included as a random effect. In addition, the coefficients of the growth models in the production regions were compared. The accuracy of the fit equations was assessed with the Akaike information criterion, Bayesian information criterion, mean absolute deviation, mean squared error, and coefficient of determination. Confidence intervals were used for comparing the production regions. The Guzerá males in the Gado-Algodão and Serra Geral da Bahia production regions were statistically equal in asymptotic weight, and the animals in the Itapetinga-Valadares and Mata-Agreste regions had equivalent maturity rates. The Guzerá females in the Itapetinga-Valadares and Serra Geral da Bahia regions had the same asymptotic weight. The maturity rates in Itapetinga-Valadares were equal to those estimated for Mata-Agreste and Serra Geral da Bahia. The inclusion of the fixed effect of the production region and the random effect of the animals in the models improved the fit quality and increased the possibility of generating growth curves for each region.(AU)

O objetivo do presente trabalho foi avaliar a acurácia dos modelos Gompertz e Von Bertalanffy ajustados, respectivamente, para machos e fêmeas da raça Guzerá, sendo incorporado nos modelos o efeito fixo de quatro regiões de produção do nordeste brasileiro e efeito aleatório de animal, além de comparar os coeficientes dos modelos de crescimento entre regiões de produção. A acurácia das equações ajustadas foi avaliada por meio do critério de informação de Akaike, critério de informação Bayesiano, desvio médio absoluto, erro quadrático médio e o coeficiente de determinação. Para comparar as regiões de produção foram utilizados intervalos de confiança. Verificou-se que machos da raça Guzerá das regiões de produção Gado-Algodão e Serra Geral da Bahia possuem peso assintótico estatisticamente igual, enquanto que a taxa de maturidade é equivalente para animais das regiões Itapetinga-Valadares e Mata-Agreste. As fêmeas da raça Guzerá das regiões de Itapetinga-Valadares e Serra Geral da Bahia possuem o mesmo peso assintótico. A taxa de maturidade em Itapetinga-Valadares é igual a estimada para Mata-Agreste e Serra Geral da Bahia. Ao incluir o efeito fixo de região de produção e aleatório de animal nos modelos, houve melhora na qualidade de ajuste e a possibilidade de gerar curvas de crescimento para cada região.(AU)

Reprodutibilidade e repetibilidade de mensuração radiográfica da silhueta cardíaca em cães da raça poodle / Reproducibility and repeatability of radiographic measurement of the cardiac silhouette in poodles

Avaliou-se o potencial de reprodutibilidade e repetibilidade de um sistema semiautomático de mensuração radiográfica. Para isto foram mensurados, por intermédio de um software o vertebral heart score (VHS) e a área cardíaca normalizada (ACN) em imagens radiográficas de cães da raça poodle clinicamente normais e portadores de insuficiência valvar mitral. Dada a subjetividade da análise da silhueta cardíaca por diferentes observadores, acredita-se que mesmo com um sistema semiautomático essa avaliação poderia ser afetada pela experiência prévia do observador em radiodiagnóstico. Foram analisadas cinquenta e sete imagens radiográficas torácicas de cães atendidos em um hospital veterinário. As imagens foram analisadas por dois grupos de observadores com diferentes níveis de experiência em radiologia: (A) sem experiência (n = 2) e (B) com experiência (n = 2). Demonstrou-se boa repetibilidade e reprodutibilidade para o VHS independente da experiência em radiodiagnóstico, e para a ACN em observadores experientes e com familiaridade com o software.

The potential of reproducibility and repeatability of a semi-automatic system of radiographic measurement was evaluated. For this purpose, the vertebral heart score (VHS) and normalized cardiac area (NCA) were evaluated in radiographs of healthy poodles and of patients with mitral regurgitation. Considering the subjective aspect of the cardiac silhouette analysis by different observers, it is believed that even with a semi-automatic system this evaluation could be affected by the previous experience of the observer in radiodiagnosis. Fifty seven thoracic images were analyzed by two groups of observers with different levels of experience in radiology: (A) without experience (n = 2) and (B) with experience (n = 2). Regardless of radiodiagnostic experience it was observed good repeatability and reproducibility for VHS, and also for ACN in observers with experience in radiodiagnostics and previous familiarity with the software.

Association of Neck Circumference with Anthropometric Indicators and Body Composition Measured by DXA in Young Spanish Adults.

BACKGROUND: Due to a clinical and public health interest of neck circumference (NC), a better understanding of this simple anthropometric measurement, as a valid marker of body composition is necessary. METHODS: A total of 119 young healthy adults participated in this study. NC was measured over the thyroid cartilage and perpendicular to the longitudinal axis of the neck. Body weight, height, waist circumference (WC), and hip circumference were measured. A Dual X-ray absorptiometry (DXA) scan was used to determine fat mass, lean mass, and visceral adipose tissue (VAT). Additionally, body mass index (BMI) and triponderal mass index (TMI), the waist to hip and waist to height ratios, and the fat mass and lean mass indexes (FMI and LMI, respectively) were calculated. RESULTS: NC was positively associated in women (W) and men (M), with BMI (rW = 0.70 and rM = 0.84, respectively), TMI (rW = 0.63 and rM = 0.80, respectively), WC (rW = 0.75 and rM = 0.86, respectively), VAT (rW = 0.74 and rM = 0.82, respectively), Waist/hip (rW = 0.51 and rM = 0.67, respectively), Waist/height (rW = 0.68 and rM = 0.83, respectively) and FMI (rW = 0.61 and rM = 0.81, respectively). The association between NC and indicators of body composition was however weaker than that observed by BMI, TMI, WC and Waist/height in both women and men. It is of note that in women, NC was associated with FMI, VAT and LMI independently of BMI. In men, adding NC to anthropometric variables did not improve the prediction of body composition, while slight improvements were observed in women. CONCLUSIONS: Taken together, the present study provides no indication for NC as a useful proxy of body composition parameters in young adults, yet future studies should explore its usefulness as a measure to use in combination with BMI, especially in women.

Nonlinear mixed effects models for comparing growth curves for Guzerá cattle / Modelos não lineares mistos para comparar curvas de crescimento de bovinos da raça Guzerá

The objective of the present work was to evaluate the accuracy of the fitted Gompertz and von Bertalanffy models for male and female Guzerá cattle, respectively. Four production regions in Northeast Brazil were included in the models as a fixed effect, and the animals were included as a random effect. In addition, the coefficients of the growth models in the production regions were compared. The accuracy of the fit equations was assessed with the Akaike information criterion, Bayesian information criterion, mean absolute deviation, mean squared error, and coefficient of determination. Confidence intervals were used for comparing the production regions. The Guzerá males in the Gado-Algodão and Serra Geral da Bahia production regions were statistically equal in asymptotic weight, and the animals in the Itapetinga-Valadares and Mata-Agreste regions had equivalent maturity rates. The Guzerá females in the Itapetinga-Valadares and Serra Geral da Bahia regions had the same asymptotic weight. The maturity rates in Itapetinga-Valadares were equal to those estimated for Mata-Agreste and Serra Geral da Bahia. The inclusion of the fixed effect of the production region and the random effect of the animals in the models improved the fit quality and increased the possibility of generating growth curves for each region.

O objetivo do presente trabalho foi avaliar a acurácia dos modelos Gompertz e Von Bertalanffy ajustados, respectivamente, para machos e fêmeas da raça Guzerá, sendo incorporado nos modelos o efeito fixo de quatro regiões de produção do nordeste brasileiro e efeito aleatório de animal, além de comparar os coeficientes dos modelos de crescimento entre regiões de produção. A acurácia das equações ajustadas foi avaliada por meio do critério de informação de Akaike, critério de informação Bayesiano, desvio médio absoluto, erro quadrático médio e o coeficiente de determinação. Para comparar as regiões de produção foram utilizados intervalos de confiança. Verificou-se que machos da raça Guzerá das regiões de produção Gado-Algodão e Serra Geral da Bahia possuem peso assintótico estatisticamente igual, enquanto que a taxa de maturidade é equivalente para animais das regiões Itapetinga-Valadares e Mata-Agreste. As fêmeas da raça Guzerá das regiões de Itapetinga-Valadares e Serra Geral da Bahia possuem o mesmo peso assintótico. A taxa de maturidade em Itapetinga-Valadares é igual a estimada para Mata-Agreste e Serra Geral da Bahia. Ao incluir o efeito fixo de região de produção e aleatório de animal nos modelos, houve melhora na qualidade de ajuste e a possibilidade de gerar curvas de crescimento para cada região.

Escore visual como uma ferramenta eficiente para identificação de bovinos precoces / Visual scores are an efficient tool for identifying precocious cattle

A hipótese testada foi a possibilidade de identificar animais que depositam gordura e músculo mais precocemente através de avaliação indireta. Assim, o objetivo desse trabalho foi verificar a possibilidade da utilização da avaliação visual de escore de precocidade na identificação de novilhas Nelore com biotipo precoce. Foram avaliadas visualmente, 18 novilhas Nelore com idade de 9 a 11 meses, por escores para estrutura corporal (E), precocidade (P) e musculosidade (M). Os animais foram separados conforme os escores de precocidade, 4, 5 e 6 foram considerados com o biotipo precoce e 1, 2 e 3 foram classificados como biotipo tardio. Tomaram-se as medidas de área de olho de lombo (AOL) e espessura de gordura subcutânea (EGS) e na picanha (EGP) por ultrassonografia. Os animais classificados como precoce receberam maiores (P ≤ 0,05) escores para E (5,1 vs 2,4) e M (4,4 vs 2,6), o que resultou em animais mais pesados (233,2 vs 202,8 kg). Não foi observado efeito (P ≥ 0,05) do biotipo para a AOL (36,5 cm2), porém, animais classificados como precoce apresentaram maior (P ≤ 0,05) EGS (1,3 vs 0,5 cm) e EGP (2,9 vs 2,3 cm). Os coeficientes canônicos padronizados revelaram que a EGP (0,78) e o escore M (-1,02) são as variáveis que mais interferem sobre a primeira variável canônica de forma positiva e negativa, respectivamente. A variação total das características avaliadas foi explicada em 100% pela primeira variável canônica. O escore de precocidade mostrou ser uma alternativa eficiente para identificação de indivíduos precoces. A diferenciação de animais com biotipo precoce foi melhor elucidada pela espessura de gordura na picanha e pelo desenvolvimento muscular do animal.

The hypothesis tested was that it is possible to identify animals that deposit fat and muscle earlier through indirect evaluation. Thus, the objective of this work was to evaluate the use of visual evaluation of precocity score for the identification of Nelore heifers with an early biotype. Eighteen Nelore heifers aged 9 to 11 months were evaluated visually for body structure (S), precocity (P), and muscle (M) scores. The animals were divided according to precocity scores: animals with scores 4, 5 and 6 were classified as early biotype and those with scores 1, 2 and 3 as late biotype. Loin eye area (LEA) and subcutaneous (SFT) and picanha (biceps femoris muscle) fat thickness (PFT) were measured by ultrasonography. Animals classified as precocious received higher scores (P≤0.05) for S (5.1 vs 2.4) and M (4.4 vs 2.6), which resulted in heavier animals (233.2 vs 202.8 kg). No biotype effect (P≥0.05) was observed for LEA (36.5 cm2), but animals classified as precocious had higher (P≤0.05) SFT (1.3 vs 0.5 cm) and PFT (2.9 vs 2.3 cm). The standardized canonical coefficients showed that PFT (0.78) and the M (-1.02) score are the variables that most affect the first canonical variable positively and negatively, respectively. The first canonical variable explained 100% of the total variation in the traits evaluated. The precocity score was found to be an efficient alternative for the identification of precocious individuals. Animals with an early biotype were better differentiated by fat thickness in the biceps femoris and by muscle development of the animal.

Scutation asymmetries in red-footed tortoise Chelonoidis carbonaria Spix, 1824 (Testudines: Testudinidae)

The ability of an individual to withstand random perturbations during its development is considered a good indicator of environmental and genetic stress. A common means of assessing developmental stability is through analysis of fluctuating asymmetry (FA) in bilateral traits. Tortoises, with their large, solid plastron, allow for measurement of body geometry. Their bilateral shell scutes are ideal candidates for asymmetries researches. With this issue in mind we assessed, as a preliminary study, levels of plastron scute asymmetry in a sample of 46 red-footed tortoise Chelonoidis carbonaria from Arauca, N Colombia. We found significative fluctuating asymmetry (FA) but no directional asymmetry, the former not increasing with carapace size and thus indicating that tortoise shells do not become increasingly asymmetrical with age, or in other words, signaling that FA is not being influenced by pholidosis (variability of scale cover mosaic according to the development of the scutes). Asymmetry in plastron shape, although not necessarily apparent at first glance, varied, with gender with males exhibiting higher levels of FA than females. Although we can not identify the potential sources of variation responsible for the observed patterns of developmental instability, we consider this detected form of asymmetry due to unfavorable environmental conditions.

Structural Analysis of the Bulbospongiosus Muscle in Patients With Bulbar Urethral Strictures.

OBJECTIVE: To characterize the bulbospongiosus muscle (BSM) in patients with bulbar urethral strictures. MATERIALS AND METHODS: We studied 21 patients divided into 2 groups: Stricture Group (n = 14; mean age = 62.00 years) with bulbar stricture submitted to open urethroplasty; and Control Group (n = 7; mean age = 60.14 years) with penile strictures (hypospadias cripples, penile cancer and/or penile infection) who were submitted to perineal urethrostomy. Samples of the BSM were dissected and histologic sections were stained by histochemical and immunohistochemical techniques. Histomorphometric analyzes were performed on photomicrographs. Means were statistically compared using the unpaired Student t test and the Mann-Whitney test (P <.05). RESULTS: The etiology of bulbar urethral stricture was idiopathic in 2 cases (14.29%), post-TURP in 6 (42.86%), post open radical prostatectomy in 5 (35.71%) and post open prostatectomy in 1 case (7.14%). The average length of the stricture was 2.08 cm. The only parameter analyzed with significant difference between the groups was the vessels (significant difference between the control group: 5.11 ± 1.98% and stricture group: 3.57 ± 1.32%, P = .0460). The quantitative analysis of collagen (Control Group: 10.63 ± 5.37% and Stricture Group: 10.83 ± 4.55%, P = .9296); diameter of BSM muscle fibers (Control Group: 41.71 ± 14.63 µm and Stricture Group: 40.11 ± 8.59 µm, P = .76 and elastic system fibers (Control Group; 3.83 ± 1.54% and Stricture Group: 5.43 ± 2.90%, P = .2601) showed no significant difference. CONCLUSIONS: Histologic analysis showed a significant decrease of the BSM vessels in urethral stricture, without changes in elastic fibers, collagen, nerves, and muscle fiber diameter. These findings show that the bulbar urethral stricture causes minimal alterations in the structure of the BSM.

Evaluation of ulnar variance on wrist MR imaging: is it a reliable measure?

OBJECTIVE: To determine if ulnar variance can be evaluated by magnetic resonance (MR) imaging and if this measure can be used as a reliable indicator when correlated to the gold standard technique, conventional radiography (CR). MATERIALS AND METHODS: From January to July 2018, the MR images of 64 participants, comprising 66 wrists (mean age 34.9 years; 33 females; 31 males), were obtained. Among those, 29 were referred for evaluation of the wrist for different medical reasons and 35 were asymptomatic volunteers from our radiology group. All subjects had a plain radiography of the wrist in a posteroanterior view with a mean interval between images of 1 day. Local ethics committee approved the study and written informed consent was obtained from all patients. Two musculoskeletal radiologists evaluated the images. Correlation coefficients and a linear regression model were used for statistical analyses. RESULTS: Intra- and inter-observer analyses were performed for both diagnostic methods with results showing concordance (intra-observer: kappa score: MR 0.915/CR 0.931; p < 0.05; inter-observer: kappa score: MR 0.857/CR 0.931; p < 0.05). The intraclass correlations of MR and CR to evaluate agreement between the radiologists was slightly higher for radiologist #1 (0.771) than for radiologist #2 (0.659). A linear regression model showed good model fit indicating that MR does correlate with the ulnar variance as measured by CR (CR = 0.554 + 0.897 × MR, R2 = 0.665). CONCLUSION: Although CR is the gold standard method for the evaluation of ulnar variance, our study demonstrated that MR can be used as a reliable qualitative option.

Tendência temporal da cobertura do Sistema de Vigilância Alimentar e Nutricional entre crianças menores de 5 anos da região Norte do Brasil, 2008-2017 / Tendencia temporal de la cobertura del Sistema de Vigilancia Alimentaria y Nutricional entre niños menores de 5 años de la Región Norte de Brasil, 2008-2017 / Temporal trend of Food and Nutrition Surveillance System coverage among children under 5 in the Northern Region of Brazil, 2008-2017

Objetivo: analisar a tendência temporal da cobertura do Sistema de Vigilância Alimentar e Nutricional Web (Sisvan Web) em menores de 5 anos de idade da região Norte brasileira, no período de 2008 a 2017. Métodos: estudo ecológico de séries temporais, com dados do Sisvan Web; a variação percentual anual (VPA) da cobertura do sistema foi estimada pelo modelo de regressão de Prais-Winsten. Resultados: na região Norte, as coberturas do SISVAN Web em 2008 e 2017 foram de 12,2% e 37,9%, respectivamente, com tendência crescente (VPA=14,2% - IC95% 10,9;17,6); os estados da região e respectivas regionais de saúde apresentaram tendências semelhantes; o Acre foi o estado que apresentou maior VPA (17,3% - IC95% 13,6;21,1). Conclusão: houve tendência crescente da cobertura do Sisvan Web na região Norte do país, assim como em todos os seus estados e regionais de saúde.

Objetivo: analizar la tendencia temporal de la cobertura del Sistema de Vigilancia Alimentaria y Nutricional (SISVAN Web) en niños menores de 5 años en la Región Norte de Brasil entre 2008-2017. Métodos: estudio ecológico de series temporales con datos del SISVAN Web; el porcentaje de variación anual (PVA) de cobertura se estimó mediante el modelo de regresión de Prais-Winsten. Resultados: en la Región Norte, la cobertura del SISVAN Web en 2008 y 2017 fue de 12,2% y 37,9%, respectivamente, con una tendencia creciente (PVA=14,2% - IC95% 10,9;17,6); los Estados y las Regionales de Salud presentaron resultados similares; Acre fue el Estado con el PVA más alto (17,3% - IC95% 13,6;21,1). Conclusión: hubo una tendencia creciente en la cobertura del SISVAN Web en todos los Estados y Regionales de Salud de la Región Norte entre 2008 y 2017.

Objective: to analyze the temporal trend of Web Food and Nutrition Surveillance System (SISVAN Web) coverage of children under 5 years old in the Northern Region of Brazil between 2008-2017. Methods: this was an ecological time series study with data from SISVAN Web; coverage annual percentage change (APC) was estimated using the Prais-Winsten regression model. Results: SISVAN Web coverage in the Northern Region in 2008 and 2017 was 12.2% and 37.9%, respectively, with a rising trend (APC=14.2% - 95%CI 10.9;17.6); the states and health regions showed similar trends; Acre was the state with the highest APC (17.3% - 95%CI 13.6;21.1). Conclusion: there was a rising trend in SISVAN Web coverage in the Northern Region as a whole, in all its states and in all its health regions.

Valor de corte del índice cintura/cadera como predictor independiente de disglucemias / Cutoff value of the waist-hip ratio as an independent predictor of dysglycemia

RESUMEN Introducción: En Cuba, no existe consenso acerca de qué valor del índice cintura/cadera debe ser considerado de riesgo para identificar disglucemias. Objetivos: Determinar el punto de corte del índice cintura/cadera como predictor de disglucemias para ambos sexos, en personas con sospecha de padecer diabetes mellitus. Métodos: Estudio descriptivo transversal con 975 personas, de ellas 523 mujeres y 452 hombres. La muestra no fue obtenida de población general y no fue aleatoria. A los sujetos se les realizó interrogatorio, examen físico y estudios complementarios. Se determinaron distribuciones de frecuencia de las variables cualitativas y cuantitativas. Se utilizó para el procesamiento estadístico el coeficiente de correlación de Pearson, análisis de regresión logística y el análisis de curvas Receiver Operator Characteristic. Se empleó la prueba Chi Cuadrado para evaluar la significación estadística. Resultados: En ambos sexos observamos una correlación directamente proporcional y significativa entre el índice cintura/cadera y las diferentes variables estudiadas, entre ellas: glucemia en ayunas y a las 2h, insulinemia en ayunas, triglicéridos, ácido úrico y el índice de resistencia a la insulina (HOMA-IR). El colesterol se comportó de la misma forma en los hombres, pero en las mujeres se verificó una correlación débil y no significativa. El punto de corte óptimo del índice cintura/cadera, como predictor independiente de disglucemias, fue de 0,85 en las mujeres y 0,93 en los hombres. El índice cintura/cadera presentó un buen poder predictivo para identificar a sujetos con y sin disglucemias para ambos sexos y superior al de la edad. Conclusiones: El punto de corte óptimo del índice cintura/cadera, como predictor independiente de disglucemias, es de 0,85 en las mujeres y 0,93 en los hombres. Su poder predictor de disglucemias fue bueno(AU)

ABSTRACT Introduction: In Cuba, there is no consensus about what value of the waist-hip ratio must be considered as a risk to identify dysglycemia. Objectives: To determine the cut-off point of the waist-hip ratio as a predictor of dysglycemias for both sexes, in people suspected of suffering from diabetes mellitus. Methods: Descriptive cross-sectional study with 975 people, including 523 women and 452 men. The sample was not obtained from general population and it was not random. The subjects underwent interrogation, physical examination and complementary studies. There were identified frequency distributions of qualitative and quantitative variables. It was used for the statistical processing the Pearson's correlation coefficient, logistic regression analysis and the curves analysis called Receiver Operator Characteristic. It was used the chi-square test to assess the statistical significance. Results: In both sexes, it was observed a directly proportional and significant correlation between the waist-hip ratio and the different variables studied, including: fasting and after 2 hours glycemia, fasting insulinemia, triglycerides, uric acid and the insulin resistance index (HOMA-IR). Cholesterol behaved the same way in men, but in women there was a weak and not significant correlation. The optimal cut-point of the waist-hip ratio, as an independent predictor of dysglycemia, was 0.85 in women and 0.93 in men. The waist-hip ratio presented a good predictive power to identify subjects with and without dysglycemia for both sexes and it was higher than that of the age. Conclusions: The optimal cut-point of the waist-hip ratio, as an independent predictor of dysglycemia, was 0.85 in women and 0.93 in men. Its power as predictor of dysglycemia was good(AU)

[Underestimation of obesity and overweight based on self-report measures in the general population: prevalence and a proposal for correction models]. / Subestimativa de obesidade e sobrepeso a partir de medidas autorrelatadas na população geral: prevalência e proposta de modelos para correção.

The study's objectives: compare self-report measures of weight and height with direct measures; assess the impact of these discrepancies on body mass index (BMI) and prevalence of overweight and obesity; and apply correction models to the self-report measures and assess the degree of improvement in the corrected measures produced with the use of these models. A cross-sectional study was performed, assessing 4,151 adults (18 to 60 years) participating in the São Paulo Megacity Epidemiological Study. Linear regression models stratified by sex were proposed for correction of self-reported measures. Agreement was assessed with the intraclass correlation coefficient for the direct measures, self-report measures, and corrected measures, and kappa coefficient for BMI classification categories. Self-reported weight and the resulting BMI were underestimated, while height was overestimated, compared to direct measures. With all the correction models, the corrected measures were closer to the direct measures. Prevalence rates for excess weight, calculated by self-report measures, were underestimated by 24% in men and by 28% in women; with corrections, the underestimation decreased to 8% and 10%, respectively. The results showed moderate agreement for self-report measures and substantial agreement for corrected measures compared to direct measures. The use of correction equations for self-report data proved to be a useful method for producing more trustworthy estimates of prevalence of overweight and obesity in the general population, usually estimated from self-report measures of weight and height in population surveys.

Os objetivos deste artigo são: (i) comparar medidas autorrelatadas de peso e estatura com medidas aferidas; (ii) avaliar o impacto dessas discrepâncias sobre o índice de massa corporal (IMC) e as prevalências de sobrepeso e obesidade; e (iii) aplicar modelos de correção das medidas autorrelatadas e avaliar o grau de melhoria das medidas corrigidas produzidas pelo uso desses modelos. Realizou-se estudo transversal, com avaliação de 4.151 adultos (18 a 60 anos) participantes do Estudo Epidemiológico dos Transtornos Mentais São Paulo Megacity. Foram propostos e testados modelos de regressão linear estratificados por sexo, para a correção das medidas autorrelatadas. Para avaliar a concordância, usou-se o coeficiente de correlação intraclasse para as medidas aferidas, medidas autorrelatadas e medidas corrigidas, bem como o coeficiente kappa para as categorias de classificação do IMC. O peso autorrelatado e o IMC resultantes foram subestimados, ao passo que a estatura foi superestimada, comparados às medidas aferidas. Com todos os modelos de correção, as medidas corrigidas tornaram-se mais próximas às medidas aferidas. As prevalências de excesso de peso, quando calculadas a partir das medidas autorrelatadas, estavam subestimadas em 24% em homens e 28% em mulheres. Com as correções, a subestimativa diminuiu para 8% e 10%, respectivamente. Identificou-se concordância moderada para as medidas autorrelatadas e concordância substancial para as medidas corrigidas, quando comparadas às medidas reais. O uso de equações de correção para dados autorrelatados mostrou-se um método útil para produzir estimativas mais fidedignas da prevalência de excesso de peso e obesidade na população geral, geralmente estimadas a partir de medidas de peso e estatura autorrelatadas nos inquéritos populacionais.

Los objetivos fueron: comparar medidas autoinformadas de peso y estatura con medidas evaluadas; evaluar el impacto de estas discrepancias sobre el índice de masa corporal (IMC) y las prevalencias de sobrepeso y obesidad; y aplicar modelos de corrección de las medidas autoinformadas y evaluar el grado de mejoría de las medidas corregidas, producidas por el uso de esos modelos. Se realizó un estudio transversal evaluando a 4.151 adultos (18 a 60 años), participantes en el Estudio Epidemiológico São Paulo Megacity. Se propusieron y probaron modelos de regresión lineal estratificados por sexo para la corrección de las medidas autoinformadas. Para evaluar la concordancia, se usó el coeficiente de correlación intraclase para las medidas evaluadas, medidas autoinformadas y medidas corregidas, y el coeficiente kappa para las categorías de clasificación del IMC. El peso autoinformado y el IMC resultantes fueron subestimados mientras la estatura fue sobrestimada, comparados con las medidas evaluadas. Con todos los modelos de corrección, las medidas corregidas se convirtieron en más cercanas a las medidas evaluadas. Las prevalencias de exceso de peso, cuando se calculan a partir de las medidas autoinformadas, estaban subestimadas en un 24% en hombres y un 28% en las mujeres; con las correcciones, la infravaloración disminuyó a un 8% y un 10%, respectivamente. Se identificó una concordancia moderada para las medidas autoinformadas y una concordancia sustancial para las medidas corregidas, cuando se compararon con las medidas reales. El uso de ecuaciones de corrección para dados autoinformados se mostró un método útil para producir estimaciones más fidedignas de la prevalencia de exceso de peso y obesidad en la población general, generalmente estimadas a partir de medidas de peso y estatura autoinformadas en las encuestas poblacionales.

Impact of bilateral nasal polyposis on the interoptic and interzygomatic distance.

PURPOSE: To identify and determine variations on eye distance in patients with bilateral nasal polyposis (BNP) compared to a healthy control group. METHODS: This is a case-control study that included 20 BNP patients and 40 healthy controls. We included all patients with BNP confirmed by pathology and a computed tomography scan. A healthy control group was admitted, filtered by the exclusion criteria of nasal polyposis, craniofacial malformations, and encephalocele. Paranasal sinus CT scans were performed in all participants, and two measures were evaluated, the interoptic (soft tissue) and the interzygomatic (bone structure) distances. RESULTS: A total of 20 BNP subjects, 13 (65%) male and 7 (35%) female, with a mean age of 38.8 years, and 40 healthy controls, 16 (40%) male and 24 (60%) female with a mean age of 43.2 years, were included. The mean interoptic distance was 69.7 mm (71.9 mm men, 66.4 mm women) and interzygomatic distance was 103.1 mm (104.5 mm men, 100.6 mm women). A significant increase of the interoptic (p < 0.001) and interzygomatic (p < 0.002) measurements was found in patients with polyposis compared to the controls. In the receptor operative curve analysis, the interoptic distance had an area under a curve of 96% and the threshold that maximizes the sensitivity and specificity was 59.85 mm (sensitivity 90%, specificity 95%, PPV 90%, NPV 95%). CONCLUSIONS: An increase in ocular and orbital distances was identified in patients with BNP. Polyposis may be identified by measuring eye separation. The established cut point distance identifies patients that may benefit from follow-up. Further research in this study line is suggested.