Erysipelas after surgery for breast cancer: a real-world cohort

Erysipelas is often related to lymphedema, which can occur in up to 60% of cases, with advanced age, radiotherapy, tumor extension, surgical approach, and infections as risk factors. The aim of this study was to present and discuss a series of cases of erysipelas after breast cancer surgery treated in a private mastology clinic over the past ten years. This is a retrospective horizontal cohort study in which we selected all cases of erysipelas after breast cancer surgery from 2009 to 2019. The following were evaluated: number of patients treated with a diagnosis of breast carcinoma with axillary approach, age, surgery performed, adjuvant treatment and treatment of erysipelas, presence of lymphedema, and measurement of circumferences between both arms and associated diseases. A total of 12 cases of breast cancer were treated. In 66.66% of cases, a radical axillary lymphadenectomy was performed, and in 16.66% of cases, only a sentinel lymph node investigation was performed. The average age was 67.6 years. Erysipelas appeared, on average, 43 months after cancer diagnosis. Two deaths were reported due to severe erysipelas leading to sepsis. More studies are still needed on the subject. Of the 12 cases in this study, eight (66.66%) were associated with lymphedema. Only two (16.66%) of the patients in this group who developed erysipelas were not submitted to axillary dissection. The treatment for 50% of the participants in this research was with penicillin G benzathine. There were three relapses, and two patients died during the research period

Carcinoma epidermoide primitivo de mama en hombre. Presentación de un caso / Primitive Epidermoid Breast Carcinoma in Men. Case Presentation

RESUMEN El carcinoma epidermoide primitivo está considerado el tumor más raro de la mama, con una incidencia que representa solo del 0,04 al 0,075 % de todos los tumores malignos de esta localización. Es una variedad de carcinoma metaplásico constituido por células pavimentosas queratinizantes. Se presenta el caso de un paciente de sexo masculino, de 65 años, de color de piel blanca, residente en el municipio Abreus, provincia Cienfuegos, que acudió a la consulta de mastología de la provincia por presentar una tumoración de 5 cms. en el cuadrante superior externo de la mama derecha, de dos meses de evolución. Se realizó exéresis de la tumoración y se recibió informe de la biopsia con el resultado de carcinoma epidermoide poco diferenciado. Actualmente el paciente se sigue en consulta y está libre de metástasis. Por lo inusual del caso se decide su publicación. Se presenta este reporte por ser el primer paciente de sexo masculino, operado de carcinoma epidermoide de mama en la provincia Cienfuegos.

ABSTRACT Primitive epidermoid carcinoma is considered the rarest breast tumor, with an incidence that represents only 0.04 to 0.05 % of all malignant tumors of this location. It is a variety of metaplastic carcinoma made up of keratinizing pavement cells. The case presented is a 65-year-old white male patient, resident in the Abreus municipality, Cienfuegos province who attended the province's mastology clinic for presenting a 5 cm tumor in the upper external quadrant of the right breast, two months in evolution. Exeresis of the tumor was performed and a report of the biopsy was received with the result of poorly differentiated squamous cell carcinoma. Currently the patient is followed in consultation and is free of metastases. Due to the unusual nature of the case, its publication is decided. This report is presented as the first male patient to undergo surgery for squamous cell carcinoma of the breast in the Cienfuegos province.

Sarcoma neurogénico de la mama masculina. Presentación de un caso / Male breast neurogenic sarcoma. A case

RESUMEN El cáncer de mama en el sexo masculino es una entidad clínica poco frecuente, tiene una presentación unimodal a los 71 años de edad, generalmente se presenta de manera similar a la forma en que se presenta en el sexo femenino. Su causa es poco conocida. Los sarcomas son tumores de componentes mesenquimatoso que constituyen del 0,2-1 % de todos los tumores de mama, y menos del 5 % del total. El sarcoma neurogénico, a su vez, es un tumor extremadamente raro. Representa del 1-2 % aproximadamente, de los tumores de los nervios periféricos con transformación maligna. Debido a la rareza geográfica e histopatológica de este tipo y mucho más en pacientes masculinos se presentó este caso. Paciente masculino de 57 años de edad, con el diagnóstico de un sarcoma de la mama derecha. Se le realizó una mastectomía radical más quimioterapia y radioterapia adyuvante. Los estudios de inmunohistoquímicos permitieron llegar al diagnóstico de sarcoma neurogénico (AU).

ABSTRACT Breast cancer in men (BCM) is a rare clinical entity that has a unimodal presentation at the age of 71 years, and generally presents in a similar way it presents in the female sex. Its etiology remains almost unknown. Sarcomas are tumors of mesenchymal components representing from 0.2 to 1 % of all the breast tumors and less than 5 % of the total. The neurogenic sarcoma is also an extremely rare tumor. It represents around 1-2 % of the peripheral nerves tumors with malignant transformations. Due to location and histopathological rarity of this kind of tumors, much more in male patients, the authors presented the case of a male patient, aged 57 years, with the diagnosis of a left breast sarcoma. He undergone a radical mastectomy plus adjuvant chemotherapy and radiotherapy. The immunohystochemical studies allowed arriving to the diagnosis of neurogenic sarcoma (AU).

Sarcoma neurogénico de la mama masculina. Presentación de un caso / Male breast neurogenic sarcoma. A case

RESUMEN El cáncer de mama en el sexo masculino es una entidad clínica poco frecuente, tiene una presentación unimodal a los 71 años de edad, generalmente se presenta de manera similar a la forma en que se presenta en el sexo femenino. Su causa es poco conocida. Los sarcomas son tumores de componentes mesenquimatoso que constituyen del 0,2-1 % de todos los tumores de mama, y menos del 5 % del total. El sarcoma neurogénico, a su vez, es un tumor extremadamente raro. Representa del 1-2 % aproximadamente, de los tumores de los nervios periféricos con transformación maligna. Debido a la rareza geográfica e histopatológica de este tipo y mucho más en pacientes masculinos se presentó este caso. Paciente masculino de 57 años de edad, con el diagnóstico de un sarcoma de la mama derecha. Se le realizó una mastectomía radical más quimioterapia y radioterapia adyuvante. Los estudios de inmunohistoquímicos permitieron llegar al diagnóstico de sarcoma neurogénico.

ABSTRACT Breast cancer in men (BCM) is a rare clinical entity that has a unimodal presentation at the age of 71 years, and generally presents in a similar way it presents in the female sex. Its etiology remains almost unknown. Sarcomas are tumors of mesenchymal components representing from 0.2 to 1 % of all the breast tumors and less than 5 % of the total. The neurogenic sarcoma is also an extremely rare tumor. It represents around 1-2 % of the peripheral nerves tumors with malignant transformations. Due to location and histopathological rarity of this kind of tumors, much more in male patients, the authors presented the case of a male patient, aged 57 years, with the diagnosis of a left breast sarcoma. He undergone a radical mastectomy plus adjuvant chemotherapy and radiotherapy. The immunohystochemical studies allowed arriving to the diagnosis of neurogenic sarcoma.

Características del cáncer de mama masculino en una población uruguaya / Characteristics of male breast cancer in a Uruguayan population / Características do câncer de mama masculino em uma população uruguaia

El cáncer de mama (CM) en el hombre (CMM) es una entidad poco frecuente. Si bien tiene algunas semejanzas con el CM femenino, es una patología con un perfil propio. El objetivo del estudio consiste en conocer las características del CMM y su manejo en nuestro medio. Materiales y métodos: estudio retrospectivo que incluyó pacientes diagnosticados de CMM en tres centros del Uruguay en un período de 15 años. Resultados: se incluyeron 12 pacientes; la mediana de edad fue 68 años; un tercio de ellos tenían antecedentes familiares (AF). Características clínico patológicas: todos los tumores fueron carcinomas ductales con grado histológico (GH) 2-3, » se hallaban en estadio (E) I, la mitad (6) en EII, 6 tuvieron metástasis axilares, 2/3 fueron receptores de estrógeno (RE) / receptores de progesterona (RP) +. Se definieron 3 subtipos biológicos: I) HER2- RE/RP+: 2/3 de los pacientes; II) HER2+: 1/6; y III) triple negativo: 1/6. Todos los pacientes con enfermedad localizada fueron sometidos a mastectomía y la mayoría recibió tratamiento con quimioterapia (QT). La totalidad de quienes presentaron enfermedad localizada RE/RP+ recibieron hormonoterapia adyuvante con buena adherencia y tolerancia. Dos de los once pacientes tratados con criterio radical recayeron en la evolución; el resto permanece en controles o tratamiento sin evidencia de recaída. Conclusión: presentamos una serie de pacientes con CMM, con un perfil similar al reportado en la literatura. La edad de presentación fue superior a la del CM femenino, y la mayoría fueron RE/RP +, HER 2-; sin embargo, en esta serie los pacientes se presentaron en estadio localizado y con tumores de alto grado en una proporción mayor a lo descrito en la literatura.

Breast cancer (BC) in men (MBC) is an uncommon clinical entity. Even though it shares some similarities with female BC, it has a distinctive profile. The objective of this study was to identify the characteristics of MBC and learn how it is managed in our setting. Materials and methods: retrospective study including patients diagnosed with MBC in three centers in Uruguay for a period of 15 years. Results: 12 patients were enrolled; the median age was 68 years; a third of whom had a family history (FH). Clinical and pathological characteristics: all of the tumors were ductal carcinomas of histological grade (HG) 2-3, 1/4 were stage (S) I, half (6) were SII, 6 had axillary metastases, 2/3 were estrogen receptor (ER) / progesterone receptor (PR) +. Three biological subtypes were defined: I) HER2- ER/PR+: 2/3 of patients; II) HER2+: 1/6; and III) triple-negative: 1/6. All patients with localized cancer underwent a mastectomy and most were treated with chemotherapy (CHT). All of those who presented with localized, ER/PR+ cancer received adjuvant hormone therapy, with good adherence and tolerance. Two of the eleven patients treated with radical surgery recurred during evolution; the rest remain in follow-up or treatment without evidence of recurrence. Conclusion: we presented a series of patients with MBC, with a profile similar to the one reported in the literature. Age at presentation was higher than that of female BC, and most were ER/PR +, HER 2-. However, patients in this series presented with breast cancer in the localized stage and high-grade tumors in a higher proportion than is described in the literature.

O câncer de mama (CM) em homens (CMM) é uma entidade clínica incomum. Embora tenha algumas semelhanças com o CM feminino, é uma patologia com o seu próprio perfil. O objetivo deste estudo foi conhecer as características do CMM e seu manejo no nosso meio. Materiais e métodos: estudo retrospectivo com pacientes com diagnóstico de CMM em três centros do Uruguai em um período de 15 anos. Resultados: foram incluídos 12 pacientes; a mediana da idade foi 68 anos; um terço deles tinha antecedentes familiares (AF). Características clínico-patológicas: todos os tumores foram carcinomas ductais de grau histológico (GH) 2-3, 1/4 estavam no estágio (E) I, a metade (6) no EII, 6 apresentaram metástases axilares, 2/3 foram receptores de estrogênio (RE) / receptores de progesterona (RP) +. Foram definidos 3 subtipos biológicos: I) HER2- RE/RP+: 2/3 dos pacientes; II) HER2+: 1/6; e III) triplo-negativo: 1/6. Todos os pacientes com doença localizada foram submetidos a mastectomia e a maioria receberam tratamento com quimioterapia (QT). A totalidade dos que apresentaram doença localizada RE/RP+ recebeu hormonioterapia adjuvante com boa adesão e tolerância. Dois dos onze pacientes tratados com critério radical recaíram na evolução; o resto permanece sob monitoramento ou tratamento sem evidência de recaída. Conclusão: apresentamos uma série de pacientes com CMM, com um perfil semelhante ao descrito na literatura. A idade de apresentação foi maior do que para o CM feminino, e a maioria foram RE/RP +, HER 2-; entretanto, os pacientes desta série apresentaram-se com estágio localizado e tumores de alto grau em uma proporção maior do que a descrita na literatura.

Papiloma intraductal metacrónico en un niño: Caso clínico / Intraductal metachronic papilloma: Clinical case

Introducción. La asociación de telorragia y ginecomastia nos orienta al diagnóstico de papiloma intraductal. Este tumor benigno es muy infrecuente en la edad pediátrica. Caso clínico. Niño de 2 años que presentó ginecomastia y telorragia en la mama izquierda. Se realizó mastectomia. A los 4 años, presentó el mismo cuadro en la mama derecha, que requirió también mastectomia derecha, con buena evolución posquirúrgica en ambas oportunidades. La anatomía patológica informó papiloma intraductal sin signos de malignidad ni atipia. Conclusión. El papiloma intraductal raramente afecta a niños; hay 15 casos reportados. La ecografía es el método de diagnóstico más empleado. En los pacientes masculinos, la mastectomia es recomendada para asegurar un diagnóstico y tratamiento definitivo.

Introduction. The association of gynecomastia and bloody nipple discharge (thelorragia) leads us to the diagnosis of intraductal papilloma. This is a very rare benign tumor in children. Clinical case. A 2 year old male child was referred due to gynecomastia and bloody nipple discharge of the left breast. A mastectomy was performed. At the age of 4 he returned with identical symptoms but in the right breast. A right mastectomy was also required. An excellent clinical outcome was present in the follow up. The pathology reported intraductal papilloma with no evidence of malignancy or atypia. Conclusion. The intraductal papilloma rarely affects children, there are 15 reported cases. Ultrasound is the most useful diagnostic method. In male patients, mastectomy is recommended to ensure definitive diagnosis and treatment.

[Intraductal metachronic papilloma: Clinical case]. / Papiloma intraductal metacrónico en un niño: Caso clínico.

INTRODUCTION: The association of gynecomastia and bloody nipple discharge (thelorragia) leads us to the diagnosis of intraductal papilloma. This is a very rare benign tumor in children. CLINICAL CASE: A 2 year old male child was referred due to gynecomastia and bloody nipple discharge of the left breast. A mastectomy was performed. At the age of 4 he returned with identical symptoms but in the right breast. A right mastectomy was also required. An excellent clinical outcome was present in the follow up. The pathology reported intraductal papilloma with no evidence of malignancy or atypia. CONCLUSION: The intraductal papilloma rarely affects children, there are 15 reported cases. Ultrasound is the most useful diagnostic method. In male patients, mastectomy is recommended to ensure definitive diagnosis and treatment.

[Synchronous bilateral breast cancer in a male]. / Carcinoma mamario bilateral sincrónico en un varón.

BACKGROUND: male breast cancer is a disease with low incidence, which is further reduced when it comes to bilateral synchronous presentation. There are few published cases in recent years. The aim is to establish guidelines for the management of this disorder that is so rare. CLINICAL CASE: a 75-year-old with tumors in both breasts, which were completely resected with removal of palpable nodes. The histopathological study reported ductal carcinoma. The indicated treatment was adjuvant tamoxifen and radiotherapy. The patient is currently in a disease-free period. CONCLUSIONS: this is a rare disease, whose main treatment is surgery, hence the importance of early diagnosis. Most cases require adjuvant chemotherapy and radiotherapy because they are usually diagnosed at an advanced stage.

antecedentes: el cáncer de mama en el hombre es una enfermedad con baja incidencia, que se reduce aún más cuando es bilateral sincrónica. Existen pocas publicaciones en los últimos años. Objetivo: establecer pautas para el tratamiento de este cáncer, aunque sea infrecuente. Caso clínico: paciente masculino de 75 años de edad, con tumores en ambas mamas, que se le resecaron completamente con exéresis de ganglios palpables. El estudio histopatológico informó que se trataba de un carcinoma ductal infiltrante no especificado. Se indicó tratamiento adyuvante con tamoxifeno y radioterapia; en la actualidad está libre de enfermedad. Conclusiones: el carcinoma mamario bilateral sincrónico en el varón es una enfermedad poco frecuente. Su tratamiento principal es la cirugía, de ahí la importancia del diagnóstico temprano. En la mayoría de los casos se requiere quimioterapia y radioterapia adyuvante porque suelen diagnosticarse en un estadio avanzado.

[Fibromatosis breast in the male. Case study]. / Fibromatosis mamaria en el varón. A propósito de un caso.

BACKGROUND: mammary fibromatosis is a rare pathology. It constitutes 0.2% of breast cancers, and case in men are exceptional. The definitive diagnosis is histological. CLINICAL CASE: we report the case of a male of 52 years, diagnosed with breast fibromatosis after pathologic study of tumor in the right breast. Programmed surgery for excision with wide margins was done. We performed a mastectomy of the subcutaneous fibromatosis with a pathologic study with clear margins. The postoperative course was uncomplicated and did not require adjuvant therapy. At 6 months follow-up he remains free of disease. The treatment of choice is surgical excision with wide margins. Adjuvant treatment is controversial. CONCLUSIONS: the fibromatosis in the breast is very rare and an exceptional occurrence in men. Surgery is the definitive treatment; few results exist for adjuvant therapy.

Antecedentes: la fibromatosis mamaria es una enfermedad rara; sus casos son 0.2% de las neoplasias de mama, y en los varones es aún más rara. El diagnóstico definitivo es anatomopatológico. Caso clínico: se comunica el caso de un varón de 52 años, con diagnóstico anatomopatológico de fibromatosis mamaria posterior al estudio de un tumor en la mama derecha. Se le practicó exéresis con amplios márgenes, luego mastectomía subcutánea, con estudio histológico de fibromatosis con márgenes libres. El postoperatorio transcurrió sin complicaciones y no requirió tratamiento coadyuvante. En el seguimiento a seis meses continuaba libre de enfermedad. El tratamiento de elección es la escisión con amplios márgenes y el oncológico coadyuvante es motivo de controversia. Conclusiones: la fibromatosis en la mama es poco frecuente y su aparición en el varón excepcional. El tratamiento quirúrgico es el definitivo, no así la terapia oncológica neoadyuvante que sigue suscitando controversia.

Carcinoma papilar intraquístico asociado a adenocarcinoma ductal infiltrante en un hombre: reporte de un caso / Papillary intra cystic carcinoma associated to ductal infiltrant adenocarcinoma in male: a case report

El carcinoma papilar intraquístico es un subtipo de carcinoma ductal no invasivo, puede estar asociado o no a carcinoma in situ y a carcinoma infiltrante, es unapatología poco frecuente por tanto su aparición en hombres es extremadamente rara. El tratamiento en estos casos es equivalente al carcinoma de mama en mujeres, debatiéndose entre mastectomía simple o mastectomía parcial más radioterapia. Presentamos el caso de un hombre a quien se diagnostica preoperatoriamente con un carcinoma papilar y se realiza mastectomía simple más ganglio centinela

The papillary intra cyst carcinoma is a sub type of ductal no invasive carcinoma, it can be associated or no to carcinoma in situ and infiltrate carcinoma, is less frequent, for this reason his apparition in male is rare. The treatment in is equivalent to breast carcinoma in women, with two modalities of treatment: simple mastectomy or simple mastectomy with radiation therapy. We present clinical case of male whom is diagnostic pre surgery with a papillary carcinoma and realized simple mastectomy with sentinel node

Case report and review of the literature: secretory breast cancer in a 13-year-old boy--10 years of follow up.

Carcinoma of the breast is very rare in childhood, accounting for less than 1% of all childhood malignancies and is especially rare in boys. Delay in diagnosis and treatment in children with breast cancer may occur because surgeons are very reluctant to perform biopsies on the developing breast, since these can cause future deformity. We report a case of male secretory breast carcinoma in a 13-year-old boy. Radical mastectomy was performed followed by chemotherapy. The patient is free of disease after 10 years. Secretory breast carcinoma (SBC) is the commonest type of breast carcinoma in children. In this article, we discuss the diagnosis and treatment options for breast cancer among children as well as features of SBC, based on a literature review.

Breast cancer in males.

BACKGROUND: Male breast cancer has a very low incidence (<1%). It has traditionally been considered to have a poorer prognosis than breast cancer in females due to delayed diagnosis as a cause of decreased survival. Our goal is to analyze our series and to identify factors influencing survival. METHODS: We conducted a retrospective study from 1997-2008 (n = 32). Inclusion criteria were male gender and histological confirmation of breast cancer. We analyzed epidemiological data (age and personal and family history), tumors (size, grade of differentiation, histological type, location, TNM stage, receptors), therapeutic regimen (surgical technique, adjuvant therapy) and survival (relapse, followup, death). RESULTS: Male breast cancer represents 0.9% of all breast cancers treated in our center. The average age of our patients was 66.84 years. Only 9.3% demonstrated gynecomastia as a presenting complaint. Histologically, 90% were infiltrating ductal type; 59.25% were diagnosed in early stages (I-II) compared to 40.74% in stages III-IV. Aggressive surgical techniques are still performed, compared to conservative techniques (74.19% vs. 19.36%). With a median follow-up of 52.82 months, the mortality rate was 16%. Existence of distant metastasis has been the only statistically significant factor in survival. CONCLUSIONS: The percentage of cases of male breast cancer is very low compared to breast cancer in females. Limited studies in the literature make gender-specific findings difficult. A low percentage of conservative surgical procedures are performed, even though this has increased considerably in recent years. The existence of distant metastasis was the main determinant of survival.

Radioguided occult lesion localization versus wire-guided localization for non-palpable breast lesions: randomized controlled trial.

AIM: This prospective randomized clinical study was conducted to compare radioguided occult lesion localization (ROLL) with wire-guided localization to evaluate optimum localization techniques for non-palpable breast lesions. METHODS: A total of 108 patients who were undergoing an excisional biopsy for non-palpable breast lesions requiring pathologic diagnosis were randomly assigned to the ROLL group (n = 56) and wire-guided localization group (n = 52). In the study, patients' characteristics, radiological abnormalities, radiological technique of localization, localization time, operation time, weight of the excised specimen, clearance margins, pathological diagnosis and perioperative complications were assessed. RESULTS: There were no differences between the two groups in terms of age, radiological abnormalities and localization technique (p = non-significant for all). ROLL techniques resulted in 100% retrieval of the lesions; for the wire-guided localization technique, 98%. Both localization time and operation time were significantly reduced with the ROLL technique (p = significant for all). The weight of the specimen was significantly lower in the ROLL group than in the wire-guided localization group (p = significant). The overall complication rate and pathological diagnosis were similar for both groups (p = non-significant for all). Clear margins were achieved in 91% of ROLL patients and in 53% of wire-guided localization patients, and the difference was significant. CONCLUSIONS: The present study indicated that the ROLL technique is as effective as wire-guided localization for the excision of non-palpable breast lesions. In addition, ROLL improved the outcomes by reducing localization and operation time, preventing healthy tissue excision and achieving clearer margins.

Radioguided occult lesion localization versus wire-guided localization for non-palpable breast lesions: randomized controlled trial

AIM: This prospective randomized clinical study was conducted to compare radioguided occult lesion localization (ROLL) with wire-guided localization to evaluate optimum localization techniques for non-palpable breast lesions. METHODS: A total of 108 patients who were undergoing an excisional biopsy for non-palpable breast lesions requiring pathologic diagnosis were randomly assigned to the ROLL group (n = 56) and wire-guided localization group (n = 52). In the study, patients' characteristics, radiological abnormalities, radiological technique of localization, localization time, operation time, weight of the excised specimen, clearance margins, pathological diagnosis and perioperative complications were assessed. RESULTS: There were no differences between the two groups in terms of age, radiological abnormalities and localization technique (p = non-significant for all). ROLL techniques resulted in 100 percent retrieval of the lesions; for the wire-guided localization technique, 98 percent. Both localization time and operation time were significantly reduced with the ROLL technique (p = significant for all). The weight of the specimen was significantly lower in the ROLL group than in the wire-guided localization group (p = significant). The overall complication rate and pathological diagnosis were similar for both groups (p = non-significant for all). Clear margins were achieved in 91 percent of ROLL patients and in 53 percent of wire-guided localization patients, and the difference was significant. CONCLUSIONS: The present study indicated that the ROLL technique is as effective as wire-guided localization for the excision of non-palpable breast lesions. In addition, ROLL improved the outcomes by reducing localization and operation time, preventing healthy tissue excision and achieving clearer margins.

Carcinoma de mama en el hombre: revisión de casos / Breast carcinoma in men: report of cases

El objetivo del presente trabajo es presentar el comportamiento clínico patológico de 8 pacientes del sexo masculino con carcinoma de la mama, atendidos en el Instituto Oncológico "Dr. Luis Razetti" durante los años 2004-2005. El cáncer de mama en hombres representó el 2,33 por ciento, 37,5 por ciento fueron adenocarcinoma ductal infiltrante, 37,5 por ciento estadio IIIA, 87,5 por ciento se trató con mastectomías radicales modificadas, 57,25 por ciento expresan receptores de estrógenos, 28,57 por ciento sobre expresan Her2neu, 37,5 por ciento recibió adyuvancia, 62,5 por ciento con tamoxifeno, el seguimiento promedio fue de 44 meses, 37,5 por ciento de recaídas local y 62,5 por ciento están libres de enfermedad a los 5 años. El cáncer de mama en hombres es muy poco frecuente. El tratamiento primario es la cirugía, siguiendo los mismos lineamientos para la adyuvancia que en las mujeres.

The objective of the present work is analyzing the clinic pathologic status of 8 patients of sex male, attending in the Oncological Institute "Dr. Luis Razetti" during the 2004-2005 years. The breast cancer in male represented the 2.33 percent, in 37.5 percent of them were ductal infiltrante adenocarcinoma, 37.5 percent were state IIIA,87.5 percent were treated with surgery: Modified radical mastectomy, 57.25 percent express estrogen receptors, 28,57 percent over express Her2neu. 37.5 percent received adjuvant, 62.5 percent with tamoxifen, the average of periodic control was 44 month, and 37.5 percent of local recurrence and 62.5 percent of the patients are free of disease to 5 years. The breast cancer in male is less frequent. The primary treatment is surgery, with the same form to the adjuvant as in women.

Carcinoma de mama en el hombre: a propósito de un caso / Breast carcinoma in men: a purpose of a case

El cáncer de mama en el hombre ha sido considerado durante mucho tiempo como una curiosidad médica, siendo la presentación clínica, la patología y la historia natural similares a la mujer, no siendo así el pronóstico. En el presente trabajo se analiza el comportamiento clínico-histológico de ocho hombres con diagnóstico de cáncer de mama en el Hospital Oncológico "Padre Machado" atendidos entre 1995 y 2006. El 75 por ciento de los pacientes se diagnósticó en estadio II y III. Un paciente en estadio IIIb tenia 23 años y está libre de enfermedad. El 66 por ciento de los pacientes presentaron receptores de estrógenos positivos. Se discuten los resultados y se revisa la literatura.

The cancer of breast in the man has been considered during long time like a medical curiosity, being the clinical presentation, the pathology and natural history similar to the woman, not being therefore the prognosis. In the present work the clinical-histological behavior of eight men with diagnosis of cancer of breast in the Hospital Oncologico “Padre Machado” is analyzed, taken care of between 1995 and 2006. 75 % of the patient’s diagnoses were in stage II and III. A patient in IIIb stage with 23 years old and he is free one of disease. 66 % of the patients presented positive estrogens receivers. The results are discussed and literature is reviewed.

Carcinoma papilar intraquístico no invasivo de mama en el hombre: reporte de un caso / Papillary intra cystic non invasive carcinoma in the men breast: a case report

El carcinoma papilar intraquístico es un subtipo de carcinoma no invasivo de la mama que comprende entre el 0,5 por ciento y 1,6 por ciento de todos los cáncer de mama. Los carcinomas papilares pueden ser divididos en forma invasiva y no invasiva y entre estos dos subtipos, una forma difusa (variante papilar de carcinoma ductal in situ) y una forma localizada (carcinoma papilar intraquístico) que es de aparición poco frecuente y con un mejor pronóstico. Su diagnóstico en un varón es una presentación extraordinariamente rara del cáncer de mama. Presentamos un caso de carcinoma papilar intraquístico no invasivo de mama en un varón de 63 años, localizado en la región retroareolar de la mama izquierda y tratado con mastectomía parcial.

The intracystic papillary carcinoma forms a small subgroup of noninvasive breast cancer comprising 0.5 % to 1.6 % of all breast cancer. Papillary carcinomas can be divided into invasive and noninvasive forms and this are further subdivided into two types, a diffuse form (the papillary variant of ductal in situ carcinoma) and a localized form, (intracystic papillary carcinomas) that is a very uncommon presentation form with a favorable prognosis. The diagnosis in a male is therefore an extremely rare presentation of breast cancer. We present a case of noninvasive intracystic papillary carcinoma of the breast in a 63 year male. The palpable mass was localized in the retroareolar region of the left breast and was treated with partial mastectomy.

Carcinoma mucinoso da mama masculina- relato de caso / Mucinous breast cancer in men - case report

O câncer de mama no homem é pouco frequente entre 0,5% e 1% dos carcinomas mamários. O tipo histológico que predomina é o carcinoma ductal; outros tipos são raros. Os autores relatam o caso de um paciente com nódulo em mama esquerda de lenta evolução, com exames de imagem suspeitos e confirmação histológica de carcinoma mucinoso. Foi submetido à mastectomia com pesquisa de linfonodo sentinela e radioterapia adjuvante. O paciente está em uso de tamoxifeno e livre de doença há vinte e nove meses. A literatura demonstra que o homem pode apresentar quase todos os tipos histológicos de câncer de mama encontrados no sexo feminino, considerando-se a excepcionalidade do tipo histológico lobular. Com base nos artigos pesquisados, foram encontrados relatos de outros cinco casos de carcinoma mucinoso em mama masculina.