Asunto(s)
Adenocarcinoma/cirugía , Neoplasias del Ciego/secundario , Siembra Neoplásica , Neoplasias del Recto/cirugía , Irrigación Terapéutica/efectos adversos , Irrigación Terapéutica/métodos , Adenocarcinoma/complicaciones , Adenocarcinoma/patología , Anciano , Drenaje , Humanos , Obstrucción Intestinal/etiología , Masculino , Neoplasias del Recto/complicaciones , Neoplasias del Recto/patologíaAsunto(s)
Neoplasias de los Conductos Biliares/patología , Conductos Biliares Intrahepáticos , Neoplasias del Ciego/secundario , Colangiocarcinoma/secundario , Hemorragia Gastrointestinal/etiología , Anciano , Neoplasias del Ciego/patología , Humanos , Inmunohistoquímica , Masculino , Persona de Mediana EdadRESUMEN
A 56-year-old man who had a history of repeated previous treatment for cystitis was admitted with abdominal distension, dysuria, pollakiuria, nocturia and sensation of urine retention after emptying the bladder. A CT scan showed a 10â cm irregularly shaped soft tissue mass abutting the anterosuperior aspect of the urinary bladder with wall thickening and a soft tissue component in the caecum. Colonoscopy revealed an encircling huge fungating mass on the caecum. The tumour was removed surgically. Histological examination showed moderately differentiated adenocarcinoma extending to the caecal wall and the bladder mucosa, the origin of the mass was consistent with that of a urachal cyst. The epicentre of the tumour was located in the bladder wall, with a distinct margin as a pathological feature. The patient was diagnosed with urachal cancer and concurrent direct caecal invasion.
Asunto(s)
Adenocarcinoma/diagnóstico , Neoplasias del Ciego/secundario , Neoplasias del Colon/diagnóstico , Neoplasias de la Vejiga Urinaria/diagnóstico , Adenocarcinoma/diagnóstico por imagen , Adenocarcinoma/patología , Neoplasias del Ciego/diagnóstico por imagen , Ciego/diagnóstico por imagen , Ciego/patología , Neoplasias del Colon/diagnóstico por imagen , Diagnóstico Diferencial , Humanos , Masculino , Persona de Mediana Edad , Invasividad Neoplásica , Tomografía Computarizada por Rayos X , Vejiga Urinaria/diagnóstico por imagen , Vejiga Urinaria/patología , Neoplasias de la Vejiga Urinaria/diagnóstico por imagen , Neoplasias de la Vejiga Urinaria/patologíaAsunto(s)
Carcinoma de Células Escamosas/secundario , Neoplasias del Ciego/complicaciones , Hemorragia Gastrointestinal/etiología , Neoplasias del Yeyuno/complicaciones , Neoplasias Orofaríngeas/patología , Neoplasias Gástricas/complicaciones , Anciano , Anemia Ferropénica/etiología , Neoplasias del Ciego/secundario , Colonoscopía , Gastroscopía , Humanos , Neoplasias del Yeyuno/patología , Neoplasias del Yeyuno/secundario , Masculino , Neoplasias Gástricas/secundarioRESUMEN
INTRODUCTION: Metastatic renal cell carcinoma (RCC) frequently spreads not only to neighboring lymph nodes, but also to distant organs, including the lungs, liver, bones and brain. CASE REPORT: We presented three cases of RCC with colon metastasis. In the first, 63-year-old patient, after left nephrectomy followed with lyphadenectomy in paraaortic lymph node, left hemicolectomy was done due to RCC metastasis in rectosigmoid colon. In the second, 35-year-old patient, left radical nephrectomy was followed two years later with partial right nephrectomy, lung metastasectomy, small bowel and coecum resection and right orchiectomy all as separate procedures in different time intervals. The patient died from brain and bone metastases two years after the first surgery. The third, 35-year-old patient, had right nephrectomy followed by repeted lymphadenectomies after 6, 12 and 24 months. Four years later RCC spreaded to coecum and right hemicolectomy was performed. CONCLUSION: RCC treated with nephrectomy should be carefully followed up with imaging methods as a proper treatment of RCC metastases to distant organs could be important for a patient survival.
Asunto(s)
Neoplasias Óseas/secundario , Neoplasias Encefálicas/secundario , Carcinoma de Células Renales/secundario , Neoplasias Colorrectales/secundario , Neoplasias Renales/patología , Neoplasias Pulmonares/secundario , Adulto , Neoplasias Óseas/cirugía , Neoplasias Encefálicas/cirugía , Carcinoma de Células Renales/cirugía , Neoplasias del Ciego/secundario , Colectomía , Neoplasias Colorrectales/cirugía , Resultado Fatal , Estudios de Seguimiento , Humanos , Neoplasias Renales/cirugía , Neoplasias Pulmonares/cirugía , Escisión del Ganglio Linfático , Masculino , Persona de Mediana Edad , Nefrectomía , Reoperación , Insuficiencia del Tratamiento , Resultado del TratamientoAsunto(s)
Abdomen Agudo/etiología , Neoplasias del Ciego/diagnóstico , Criptorquidismo/diagnóstico , Neoplasias de Células Germinales y Embrionarias/diagnóstico , Neoplasias del Colon Sigmoide/diagnóstico , Neoplasias Testiculares/diagnóstico , Adulto , Neoplasias del Ciego/complicaciones , Neoplasias del Ciego/secundario , Criptorquidismo/complicaciones , Humanos , Masculino , Neoplasias de Células Germinales y Embrionarias/complicaciones , Neoplasias de Células Germinales y Embrionarias/secundario , Neoplasias del Colon Sigmoide/complicaciones , Neoplasias del Colon Sigmoide/secundario , Neoplasias Testiculares/complicaciones , Neoplasias Testiculares/patologíaAsunto(s)
Neoplasias del Ciego/secundario , Enfermedades del Íleon/etiología , Neoplasias del Íleon/secundario , Válvula Ileocecal , Intususcepción/etiología , Melanoma/complicaciones , Melanoma/secundario , Anciano de 80 o más Años , Neoplasias del Ciego/complicaciones , Femenino , Humanos , Neoplasias del Íleon/complicaciones , Neoplasias del Recto/patologíaRESUMEN
Metastasis to the abdominal wall including port sites after laparoscopic surgery for colorectal cancer is rare. Resection of metastatic lesions may lead to greater survival benefit if the abdominal wall metastasis is the only manifestation of recurrent disease. A 57-year-old man, who underwent laparoscopic surgery for advanced mucinous adenocarcinoma of the cecum 6 years prior, developed a nodule in the surgical wound at the lower right abdomen. Although tumor markers were within normal limits, the metastasis to the abdominal wall and abdominal cavity from the previous cecal cancer was suspected. An abdominal computed tomography scan did not provide detective evidence of metastasis. (18)F-fluorodeoxyglucose positron emission/computed tomography ((18)F-FDG PET/CT) was therefore performed, which demonstrated increased (18)F-fluorodeoxyglucose uptake (maximum standardized uptake value: 3.1) in the small abdominal wall nodule alone. Histopathological examination of the resected nodule confirmed the diagnosis of metastatic mucinous adenocarcinoma. Prognosis of intestinal mucinous adenocarcinoma is reported to be poorer than that of non-mucinous adenocarcinoma. In conclusion, this case suggests an important role of (18)F-FDG PET/CT in early diagnosis and decision-making regarding therapy for recurrent disease in cases where a firm diagnosis of recurrent colorectal cancer is difficult to make.
Asunto(s)
Pared Abdominal/patología , Adenocarcinoma Mucinoso/secundario , Neoplasias del Ciego/secundario , Neoplasias Colorrectales/patología , Fluorodesoxiglucosa F18 , Tomografía de Emisión de Positrones , Tomografía Computarizada de Emisión , Pared Abdominal/cirugía , Adenocarcinoma Mucinoso/cirugía , Neoplasias del Ciego/cirugía , Neoplasias Colorrectales/cirugía , Humanos , Masculino , Persona de Mediana Edad , Pronóstico , RadiofármacosAsunto(s)
Adenocarcinoma/patología , Adenocarcinoma/secundario , Neoplasias del Ciego/secundario , Pólipos del Colon/patología , Neoplasias Gástricas/patología , Adenocarcinoma/complicaciones , Anciano , Neoplasias del Ciego/patología , Colectomía , Pólipos del Colon/complicaciones , Humanos , Laparoscopía , Masculino , Neoplasias Gástricas/complicacionesRESUMEN
A patient with phyllodes tumour of the breast is discussed. During follow-up, she presented with intestinal obstruction caused by ileocaecal intussusception. The cause of the intussusception was metastatic phyllodes tumour, which is a unique presentation.
Asunto(s)
Neoplasias de la Mama , Neoplasias del Ciego/secundario , Válvula Ileocecal , Intususcepción/etiología , Tumor Filoide/secundario , Neoplasias del Ciego/complicaciones , Neoplasias del Ciego/patología , Femenino , Humanos , Enfermedades del Íleon/diagnóstico por imagen , Enfermedades del Íleon/etiología , Válvula Ileocecal/diagnóstico por imagen , Intususcepción/diagnóstico por imagen , Persona de Mediana Edad , Tumor Filoide/complicaciones , Tumor Filoide/patología , Tomografía Computarizada por Rayos XRESUMEN
During the period from 2001 to 2005 operations were performed on 186 patients with locally-spread colorectal cancer. In 132 cases (the 1st group) radical combined resections were performed, 54 patients (the 2nd group) underwent palliative operations. The morbidity rate was 18.2% (24 cases) in the first group and 7.4% (4 cases) in the second group. The mortality rate in the first group was 2.3% (3 cases), no mortality was observed in the second group. Overall 3-year survival in the first group was 69.9%, and no one patient of the second group survived longer than 3 years. Overall 5-year survival in the first group was 54.7%, and the relapse-free 5-year survival was 52.8%. The data obtained have shown the effectiveness of combined resections in treatment of locally-spread colorectal cancer. We suggest that further improvement of long-term results can be achieved using chemoradiation.
Asunto(s)
Adenocarcinoma/cirugía , Neoplasias del Ciego/cirugía , Colectomía/métodos , Neoplasias Colorrectales/cirugía , Neoplasias del Colon Sigmoide/cirugía , Adenocarcinoma/mortalidad , Adenocarcinoma/secundario , Neoplasias del Ciego/mortalidad , Neoplasias del Ciego/secundario , Neoplasias Colorrectales/mortalidad , Neoplasias Colorrectales/patología , Supervivencia sin Enfermedad , Femenino , Estudios de Seguimiento , Humanos , Masculino , Recurrencia Local de Neoplasia/epidemiología , Estudios Retrospectivos , Federación de Rusia/epidemiología , Neoplasias del Colon Sigmoide/mortalidad , Neoplasias del Colon Sigmoide/secundario , Tasa de Supervivencia/tendencias , Factores de Tiempo , Resultado del TratamientoRESUMEN
HISTORY AND CLINICAL FINDINGS: A slightly confused and apathic 78-year-old woman presented in a deteriorating general condition and unspecific symptoms with (diarrhea, vomiting, nausea). INVESTIGATIONS: Laboratory tests revealed megalocytic anemia with vitamin B12 deficiency. As a cause, atrophic gastritis was suspected. Esophagogastroduodenoscopy with multiple "gastric mapping" biopsies revealed diffuse infiltration by an adenocarcinoma in 12 out of 14 gastric biopsy sites. Surprisingly, this malignant tissue was identified by immunohistochemistry as a diffuse infiltration by an as yet unrecognized breast cancer. Immunohistochemically identical infiltrations were identified in the cecum by colonoscopy. TREATMENT AND COURSE: Subsequent mammography identified a retromammilar primary tumor in the right breast. Because of the patient's poor general condition merely palliative therapy with oral tamoxifen was initiated. CONCLUSION: The correct diagnosis and appropriate therapy of gastric and coecal metastases secondary to an as yet unrecognized breast cancer were rendered possible only by additional immunohistochemical testing with specific antibodies against the estrogen receptor, cytoceratin (CK) 20 and 7 and E-cadherin.
Asunto(s)
Adenocarcinoma/secundario , Neoplasias de la Mama/patología , Neoplasias del Ciego/secundario , Neoplasias Gástricas/secundario , Adenocarcinoma/diagnóstico , Administración Oral , Anciano , Antineoplásicos Hormonales/administración & dosificación , Neoplasias de la Mama/diagnóstico , Neoplasias del Ciego/diagnóstico , Neoplasias del Ciego/terapia , Diagnóstico Diferencial , Endoscopía del Sistema Digestivo , Femenino , Mucosa Gástrica/patología , Gastritis Atrófica/diagnóstico , Humanos , Inmunohistoquímica , Mucosa Intestinal/patología , Mamografía , Cuidados Paliativos , Neoplasias Gástricas/diagnóstico , Neoplasias Gástricas/terapia , Tamoxifeno/administración & dosificaciónRESUMEN
A 63-year-old man who had general malaise and dyspnea on effort, was admitted to our hospital. Chest X-ray film on admission showed left pleural effusion. Chest and abdominal CT after left chest drainage revealed left pleural thickening, mediastinal lymph node swelling, multiple lung nodules, osteolytic change of the left 4th rib, and multiple liver tumors. Right pleural effusion and ascites was also recognized. Cytology of the left pleural effusion suggested malignant mesothelioma. He had a skin tumor on his anterior chest. Biopsy revealed metastasis of malignant epithelioid mesothelioma. Upper gastrointestinal endoscopy showed a duodenal tumor and colonoscopy showed a cecal erosion. Endoscopic biopsy revealed metastases of malignant mesothelioma identical to the skin tumor. Because of the left pleural thickening, the primary site was considered to be in the left pleura. Here we report a case of malignant pleural mesothelioma (MPM) with multiple distant metastases to the duodenum, cecum, skin, lung, liver, and rib. Gastrointestinal metastases of MPM detected by endoscopic biopsy are very rare. Only one case of cecal metastasis has ever been reported.
Asunto(s)
Neoplasias del Ciego/secundario , Neoplasias Duodenales/secundario , Mesotelioma/patología , Neoplasias Pleurales/patología , Biopsia , Endoscopía , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Cutáneas/secundarioAsunto(s)
Carcinoma Neuroendocrino/secundario , Neoplasias del Ciego/secundario , Neoplasias del Cuello Uterino/terapia , Carcinoma Neuroendocrino/diagnóstico por imagen , Carcinoma Neuroendocrino/terapia , Neoplasias del Ciego/diagnóstico por imagen , Femenino , Humanos , Persona de Mediana Edad , Tomografía Computarizada por Rayos XRESUMEN
BACKGROUND: Gastrointestinal metastsasis from the breast cancer are rare. We report a patient who presented with intestinal obstruction due to solitary caecal metastasis from infiltrating ductal carcinoma of breast. We also review the available literature briefly. CASE PRESENTATION: A 72 year old lady with past history of breast cancer presented with intestinal obstruction due to a caecal mass. She underwent an emergency right hemicolectomy. The histological examination of the right hemicolectomy specimen revealed an adenocarcinoma in caecum staining positive for Cytokeratin 7 and Carcinoembryonic antigen and negative for Cytokeratin 20, CDX2 and Estrogen receptor. Eight out of 11 mesenteric nodes showed tumour deposits. A histological diagnosis of metastatic breast carcinoma was given. CONCLUSION: To the best of our knowledge, this is the first case report of solitary metastasis to caecum from infiltrating ductal carcinoma of breast. Awareness of this possibility will aid in appropriate management of such patients.
Asunto(s)
Neoplasias de la Mama/patología , Neoplasias del Ciego/secundario , Obstrucción Intestinal/etiología , Anciano , Biomarcadores de Tumor/análisis , Factor de Transcripción CDX2 , Antígeno Carcinoembrionario/análisis , Neoplasias del Ciego/complicaciones , Neoplasias del Ciego/patología , Femenino , Proteínas de Homeodominio/análisis , Humanos , Queratina-7/análisisRESUMEN
Small bowel metastases from a primary lung carcinoma are rare. We report a case of a 59-year-old male with a primary small-cell lung carcinoma who developed anaemia and bowel symptoms. On colonoscopic examination he was found to have a tumour in the caecum near the ileocaecal valve, which was biopsied, revealing small neuroendocrine tumour cells. The patient then underwent systemic chemotherapy, which achieved a reduction in the size of the primary lung tumour and an improvement in his bowel symptoms. It is important that such a rare condition be recognised early as complicated intestinal metastases from a lung carcinoma can lead to high mortality rates and poor short-term outcome. With advances in chemotherapy and palliative care, patients with metastatic lung carcinoma can sometimes survive more than a year with reasonable quality of life.
Asunto(s)
Carcinoma de Células Pequeñas/secundario , Neoplasias del Ciego/secundario , Neoplasias Pulmonares/diagnóstico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Biopsia , Neoplasias del Tronco Encefálico/patología , Neoplasias del Tronco Encefálico/radioterapia , Neoplasias del Tronco Encefálico/secundario , Carboplatino/administración & dosificación , Carcinoma de Células Pequeñas/diagnóstico , Carcinoma de Células Pequeñas/tratamiento farmacológico , Carcinoma de Células Pequeñas/patología , Neoplasias del Ciego/diagnóstico , Neoplasias del Ciego/tratamiento farmacológico , Neoplasias del Ciego/patología , Ciego/patología , Colonoscopía , Terapia Combinada , Irradiación Craneana , Etopósido/administración & dosificación , Humanos , Neoplasias Pulmonares/tratamiento farmacológico , Neoplasias Pulmonares/patología , Metástasis Linfática/patología , Masculino , Persona de Mediana EdadRESUMEN
Lung cancer is the leading cause of cancer mortality in the developed world, and often presents with metastatic disease. Metastatic lung cancer rarely presents with gastrointestinal symptoms, but we report a case of an elderly male with metastatic lung carcinoma to the cecum who presented with melena. The patient required blood transfusions, but eventually died of septic shock. This case is consistent with previously reported cases of lung cancer metastatic to the gastrointestinal tract which suggest that tumor-associated bleeding in this patient population is a pre-terminal event.
Asunto(s)
Adenocarcinoma/diagnóstico , Neoplasias del Ciego/secundario , Hemorragia Gastrointestinal/etiología , Neoplasias Pulmonares/diagnóstico , Adenocarcinoma/complicaciones , Adenocarcinoma/patología , Anciano , Neoplasias del Ciego/patología , Resultado Fatal , Hemorragia Gastrointestinal/patología , Humanos , Neoplasias Pulmonares/complicaciones , Neoplasias Pulmonares/patología , MasculinoRESUMEN
The unusual case of an adenocarcinoma of the caecum undiagnosed until the appearance of a large neck and axillary mass is reported. To our knowledge, this is the first reported case of cervical node metastasis as the first sign of a caecal cancer, and 18 fluorine-18-labeled 2-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) proved critical in achieving the correct diagnosis. When an adenocarcinoma is found in the neck or axilla, even an abdominal primary location such as the large bowel can be taken into account and employment of FDG-PET should be considered.
Asunto(s)
Neoplasias del Ciego/secundario , Neoplasias del Cuello Uterino/patología , Anciano , Neoplasias del Ciego/diagnóstico , Medios de Contraste , Femenino , Fluorodesoxiglucosa F18 , Humanos , Inmunohistoquímica , Masculino , Metástasis de la Neoplasia , Tomografía de Emisión de Positrones , Tomografía Computarizada por Rayos XRESUMEN
BACKGROUND: Pancreatic cancer is often locally and distally aggressive, but initial presentation as cecal perforation is uncommon. CASE PRESENTATION: We describe a patient presenting with pneumoperitoneum, found at initial exploration to have a cecal perforation believed to be secondary to a large cecal adenoma, after palpation of the remainder of the colon revealed hard stool but no distal obstruction. Postoperatively, however, the patient progressed to large bowel obstruction and upon reexploration, a mass could now be delineated, encompassing the splenic flexure, splenic hilum, and distal pancreas. Histological evaluation determined this was locally invasive pancreatic adenocarcinoma, and therefore the true etiology of the original cecal perforation. CONCLUSION: Any perforation localized to the cecum must be highly suspicious for a distal obstruction, as dictated by the law of LaPlace.
Asunto(s)
Adenocarcinoma/secundario , Neoplasias del Ciego/secundario , Perforación Intestinal/etiología , Invasividad Neoplásica/patología , Neoplasias Pancreáticas/patología , Dolor Abdominal/diagnóstico , Dolor Abdominal/etiología , Adenocarcinoma/complicaciones , Adenocarcinoma/cirugía , Anciano , Biopsia con Aguja , Neoplasias del Ciego/complicaciones , Neoplasias del Ciego/diagnóstico por imagen , Neoplasias del Ciego/cirugía , Servicio de Urgencia en Hospital , Estudios de Seguimiento , Humanos , Inmunohistoquímica , Perforación Intestinal/patología , Perforación Intestinal/cirugía , Laparotomía/métodos , Masculino , Estadificación de Neoplasias , Neoplasias Pancreáticas/complicaciones , Neoplasias Pancreáticas/cirugía , Medición de Riesgo , Tomografía Computarizada por Rayos XRESUMEN
BACKGROUND: Prostatic carcinoma is the second most common cause of cancer-related deaths in males in the West. Approximately 20% of patients present with metastatic disease. We describe the case of a patient with metastatic prostate cancer to the bowel presenting clinically and radiologically as a primary caecal cancer. CASE PRESENTATION: A 72 year-old man presented with abdominal discomfort and a clinically palpable caecal mass and a firm nodule on his thigh, the latter behaving clinically and radiologically as a lipoma. Computed tomographic (CT) scan showed a luminally protuberant caecal mass with regional nodal involvement. The patient was being treated (Zoladex) for prostatic cancer diagnosed 6 years previously and was known to have bony metastases. On admission his PSA was 245.4 nmol/ml. The patient underwent a right hemicolectomy. Histology showed a poorly differentiated adenocarcinoma which was PSA positive, confirming metastatic prostatic adenocarcinoma to the caecum. The patient underwent adjuvant chemotherapy and is free from recurrence a year later. CONCLUSION: Metastasis of prostatic carcinoma to the bowel is a very rare occurrence and presents a challenging diagnosis. The diagnosis is supported by immunohistochemistry for PSA. The treatment for metastatic prostate cancer is mainly palliative.