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1.
Headache ; 60(1): 247-258, 2020 01.
Artículo en Inglés | MEDLINE | ID: mdl-31749202

RESUMEN

BACKGROUND/OBJECTIVE: The great auricular nerve (GAN) arises from C2-C3 and provides innervation over the skin in the pre-auricular region, jaw angle, posteroinferior pinna, and mastoid. Although damage to the GAN has been reported following trauma or procedures nearby this nerve course, neuralgia of this nerve is uncommon with knowledge based on a handful of case reports in literature. The objective of this study is to describe the presentation, treatment, and outcome of 13 cases of GAN neuralgia. METHODS: Case series. Retrospecive review of charts from 1994 to 2018 with diagnoses: "auricular neuralgia," "auricular neuritis," or "auricular neuropathy." We included subjects with neuralgic pain within the distribution of the GAN, and excluded patients with atypical facial pain, GAN neuropathy, or unclear etiology. RESULTS: Of 79 charts, 13 patients met criteria (age at onset 11-59; 11 women, 2 men). Pain was most often described as paroxysmal stabbing provoked by: turning the head (n = 7), touching the neck (n = 5), neck position during sleep (n = 2), jaw movement (n = 2), and other (n = 2). Seven patients received GAN blocks: all noted dramatic improvement in pain, including 3 who continued to receive serial blocks at our institution successfully for the next 2 to 5 years. Two patients successfully transitioned from GAN blocks to GAN stimulators. One patient with GAN lymphoma had resolution of pain following GAN resection. CONCLUSION: GAN neuralgia should be considered in the differential for periauricular pain. GAN blocks or stimulators may be helpful for pain management.


Asunto(s)
Plexo Cervical/fisiopatología , Bloqueo Nervioso , Neuralgia/fisiopatología , Neuralgia/terapia , Adulto , Plexo Cervical/efectos de los fármacos , Plexo Cervical/cirugía , Niño , Terapia por Estimulación Eléctrica , Femenino , Humanos , Masculino , Persona de Mediana Edad , Bloqueo Nervioso/instrumentación , Bloqueo Nervioso/métodos , Neuralgia/diagnóstico , Neuralgia/etiología , Procedimientos Neuroquirúrgicos , Estudios Retrospectivos , Resultado del Tratamiento
2.
Eur. J. Ost. Clin. Rel. Res ; 13(2): 56-59, abr.-ago. 2018.
Artículo en Español | IBECS | ID: ibc-200990

RESUMEN

INTRODUCCIÓN: La cervicalgia es un transtorno muscoloesquelético muy frecuente en las consultas de Osteopeatía, afectando al 45-54% de la población a lo largo de su vida. Se define como un dolor localizado entre occipucio y la tercera vértebra dorsal. La mayoría de pacientes con cervicalgia no solucionan completamente sus síntomas y su discapacidad, evolucionando con periodos de remisión y exarcerbación. El músculo trapecio es un importante estabilizador escapular e interviene mediante contracción mantenida en la posición de la cabeza. La neuropatía del nervio espinalpodría degenerar la fibra muscular (atrofia o fibrosis) presentando el trapecio las bandas tensas típicas del dolor miosfacial cervical. OBJETIVO: Exponer la relación existente entre la cervicalgia mecánica, el trapecio superior y su inervación a través del nervio espinal (XI). MATERIAL Y MÉTODOS: Se ha realizado una revisión bibliográfica y posterior comentario de una serie de artículos que relacionan la neuropatía del XI par craneal y consecuente afectación del trapecio, en los pacientes con disfunciones miosfaciales cervicales. RESULTADOS: Existe cierta evidencia científica que relaciona las disfunciones del nervio espinal y sus repercusiones en el trapecio superior en los individuos con dolor cervical. CONCLUSIONES: El osteópata debe realizar una correcta evaluación del agujero rasgado posterior y su contenido vasculonervioso para tratar y prevenir las implicaciones del trapecio superior en las cervicalgias


No disponible


Asunto(s)
Humanos , Nervios Espinales/fisiopatología , Dolor de Cuello/fisiopatología , Hueso Trapecio/fisiopatología , Plexo Cervical/fisiopatología , Estudios de Casos y Controles , Medicina Osteopática/tendencias
3.
Lancet Neurol ; 17(2): 174-182, 2018 02.
Artículo en Inglés | MEDLINE | ID: mdl-29229375

RESUMEN

The understanding of migraine pathophysiology is advancing rapidly. Improved characterisation and diagnosis of its clinical features have led to the view of migraine as a complex, variable disorder of nervous system function rather than simply a vascular headache. Recent studies have provided important new insights into its genetic causes, anatomical and physiological features, and pharmacological mechanisms. The identification of new migraine-associated genes, the visualisation of brain regions that are activated at the earliest stages of a migraine attack, a greater appreciation of the potential role of the cervical nerves, and the recognition of the crucial role for neuropeptides are among the advances that have led to novel targets for migraine therapy. Future management of migraine will have the capacity to tailor treatments based on the distinct mechanisms of migraine that affect individual patients.


Asunto(s)
Manejo de la Enfermedad , Trastornos Migrañosos/fisiopatología , Encéfalo/fisiopatología , Plexo Cervical/fisiopatología , Análisis Mutacional de ADN , Estudio de Asociación del Genoma Completo , Humanos , Trastornos Migrañosos/diagnóstico , Trastornos Migrañosos/genética , Trastornos Migrañosos/terapia , Neuropéptidos/fisiología , Factores de Riesgo
4.
Biomed Res Int ; 2017: 4654803, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28326321

RESUMEN

Objective. The aim of this study was to compare the efficacy of ultrasound-guided deep cervical plexus block with fluoroscopy-guided deep cervical plexus block for patients with cervicogenic headache (CeH). Methods. A total of 56 patients with CeH were recruited and randomly assigned to either the ultrasound-guided (US) or the fluoroscopy-guided (FL) injection group. A mixture of 2-4 mL 1% lidocaine and 7 mg betamethasone was injected along C2 and/or C3 transverse process. The measurement of pain was evaluated by patients' ratings of a 10-point numerical pain scale (NPS) before and 2 wks, 12 wks, and 24 wks after treatments. Results. The blocking procedures were well tolerated. The pain intensity, as measured by NPS, significantly decreased at 2 wks after injection treatment in both US and FL groups, respectively, compared with that of baseline (P < 0.05). The blocking procedures had continued, and comparable pain relieving effects appeared at 12 wks and 24 wks after treatment in both US and FL groups. There were no significant differences observed in the NPS before and 2 wks, 12 wks, and 24 wks after treatment between US and FL groups. Conclusions. The US-guided approach showed similar satisfactory effect as the FL-guided block. Ultrasonography can be an alternative method for its convenience and efficacy in deep cervical plexus block for CeH patients without radiation exposure.


Asunto(s)
Bloqueo del Plexo Cervical/métodos , Fluoroscopía/métodos , Manejo del Dolor/métodos , Cefalea Postraumática/tratamiento farmacológico , Adulto , Anciano , Betametasona/administración & dosificación , Plexo Cervical/efectos de los fármacos , Plexo Cervical/fisiopatología , Vértebras Cervicales/efectos de los fármacos , Vértebras Cervicales/fisiopatología , Femenino , Humanos , Lidocaína/administración & dosificación , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Cefalea Postraumática/fisiopatología , Ultrasonografía Intervencional/métodos
5.
Invest Ophthalmol Vis Sci ; 57(4): 1749-56, 2016 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-27070108

RESUMEN

PURPOSE: Herpes simplex virus type 1 (HSV-1) is a neurotrophic virus that can cause herpes stromal keratitis (HSK), a severe corneal inflammation that can lead to corneal scarring and blindness. This study identified neurologic changes that occur in HSV-1-infected corneas and related them to HSV-1-induced immunopathology. METHODS: Corneas of BALB/c and C57BL/6 mice were infected with HSV-1 strains that induce HSK. Changes in sensory nerves were identified by immunofluorescence staining of sensory and sympathetic nerves for substance P (SP) and tyrosine hydroxylase (TH), respectively, and confocal microscopic examination. Some mice received superior cervical ganglionectomy (SCGx) to eliminate sympathetic nerves from the cornea. RESULTS: Normal corneas exclusively expressed sensory nerves that entered the stroma as large nerve stalks, branched to form a plexus at the epithelial/stromal interface, and extended termini into the epithelium. These nerves completely retracted from the infected cornea and were replaced by sympathetic nerves that sprouted extensively to hyperinnervate the corneal stroma but failed to form a plexus or extend termini into the epithelium. The hyperinnervating nerves expressed the sympathetic nerve marker TH and their invasion was blocked by performing SCGx. Moreover, the corneal opacity and neovascularization that normally characterizes HSK in this mouse model were largely abrogated by SCGx. Sensory nerves reinnervated infected corneas following SCGx, reformed a nerve plexus, and extended termini into the epithelium resulting in recovery of corneal sensitivity. CONCLUSIONS: Sympathetic nerves have a central role in HSK in mice, preventing reinnervation by sensory nerves and promoting severe and persistent corneal inflammation.


Asunto(s)
Parpadeo/fisiología , Plexo Cervical/fisiopatología , Sustancia Propia/inervación , Infecciones Virales del Ojo/patología , Queratitis Herpética/patología , Sistema Nervioso Simpático/fisiopatología , Animales , Plexo Cervical/cirugía , Plexo Cervical/virología , Sustancia Propia/patología , Modelos Animales de Enfermedad , Infecciones Virales del Ojo/fisiopatología , Infecciones Virales del Ojo/virología , Femenino , Ganglionectomía , Herpesvirus Humano 1/patogenicidad , Inmunohistoquímica , Queratitis Herpética/fisiopatología , Queratitis Herpética/virología , Ratones , Ratones Endogámicos BALB C , Microscopía Confocal , Fotomicrografía , Índice de Severidad de la Enfermedad , Sistema Nervioso Simpático/virología , Grabación en Video
6.
Childs Nerv Syst ; 32(2): 243-51, 2016 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-26280631

RESUMEN

BACKGROUND: Pain of spinal origin contributes significantly to cervical, thoracic, and lower back pain presentations. Such pain originates in the nerve fibers supplying the joints or the surrounding ligaments and intervertebral discs. Although there has been little detailed discussion of spinal bony innervation patterns in the literature, the clinical implications of these patterns are anatomically and medically significant. METHODS: The present review provides a detailed analysis of the innervation of the spine, identifying the unique features of each part via online search engines. CONCLUSIONS: The clinical implications of these various studies lie in the importance of the innervation patterns for the mechanism of spinal pain. Immunohistochemical studies have provided further evidence regarding the nature of the innervation of the spine.


Asunto(s)
Dolor de Espalda/fisiopatología , Disco Intervertebral/inervación , Ligamentos/inervación , Dolor de Cuello/fisiopatología , Plexo Cervical/fisiopatología , Humanos , Inmunohistoquímica , Plexo Lumbosacro/fisiopatología , Articulación Sacroiliaca/inervación , Nervios Espinales/fisiopatología , Columna Vertebral/inervación , Articulación Cigapofisaria/inervación
7.
Neuromodulation ; 17(3): 256-63; discussion 263-4, 2014 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-24118206

RESUMEN

OBJECTIVE: The goal of this study is to evaluate the effectiveness of occipital nerve stimulation (ONS) as a surgical treatment for fibromyalgia in a placebo-controlled design. MATERIALS AND METHODS: Eleven patients were selected based on the American College of Rheumatology-90 criteria and implanted with an occipital nerve trial-lead stimulator. Baseline scores for pain, mood, and fatigue were acquired, and patients were randomized in a ten-week double-blinded crossover design with placebo and effective subsensory threshold stimulation (no paresthesias). After finalizing the trial, nine patients were implanted permanently; evaluation was performed prior to surgery and at six months after surgery for pain, fatigue, and mood of the number of trigger points and overall morbidity. RESULTS: Significant results were found during the trial for a decrease in pain intensity (39.74%) on visual analogue scale (VAS; p < 0.001) and pain catastrophizing scale (PCS) during effective stimulation. A total of 9/11 patients responded to trial treatment; however, in two patients, this might be a placebo effect, recognizable due to the study design. Six months after permanent implantation, pain intensity remained decreased (44.01%) on VAS (p < 0.05). Besides the VAS, significant changes were noted for PCS, fatigue (modified fatigue impact scale), the number of trigger points, and overall morbidity (fibromyalgia impact questionnaire). There were no serious adverse events. CONCLUSIONS: Our data strongly suggest that ONS is beneficial in the treatment of fibromyalgia. The beneficial effects are stable at six months after permanent implantation. Subsensory threshold stimulation is feasible in designing a placebo-controlled trial.


Asunto(s)
Plexo Cervical/fisiopatología , Terapia por Estimulación Eléctrica/métodos , Electrodos Implantados , Fibromialgia/terapia , Adulto , Afecto , Estudios Cruzados , Método Doble Ciego , Terapia por Estimulación Eléctrica/instrumentación , Electrodos Implantados/efectos adversos , Fatiga/etiología , Fatiga/terapia , Femenino , Fibromialgia/complicaciones , Fibromialgia/psicología , Estudios de Seguimiento , Humanos , Persona de Mediana Edad , Manejo del Dolor , Aceptación de la Atención de Salud , Proyectos Piloto , Filtrado Sensorial , Tejido Subcutáneo , Escala Visual Analógica
8.
Zhen Ci Yan Jiu ; 38(1): 1-6, 2013 Feb.
Artículo en Chino | MEDLINE | ID: mdl-23650792

RESUMEN

OBJECTIVE: To observe the effect of electroacupuncture (EA) combined with cervical plexus block (CPB) on the stress response of patients undergoing thyroid surgery. METHODS: Forty thyroidectomy patients were randomly divided into sham EA plus CPB group (sham group) and EA+CPB group (20 cases in each group). For patients of the sham group, deep cervical plexus block (25% ropivacaine hydrochloride + 1% lidocaine hydrochloride) was performed first, followed by inserting acupuncture needles into bilateral Hegu (LI 4) and Neiguan (PC 6) separately without needle manipulation and then connecting the output wires of the EA therapeutic instrument to the handles of the acupuncture needles but without electric current output. For patients of the EA+CPB group, deep cervical plexus block was performed first followed by EA stimulation [10 Hz, (6 +/- 2) mA] of the bilateral LI 4 and PC 6 for 20 min. Systolic blood pressure (SBP), heart rate (HR) and breathing frequency were detected using a multipurpose monitor. Plasma adrenocorticotropic hormone (ACTH) and cortisol (Cor) contents were determined using chemiluminescence method, plasma epinephrine (E) level was detected by enzyme-linked immunosorbent assay, glucose (Glu) assayed by oxidase method, and plasma C-reactive protein (CRP) level detected using immumofluorescence technique. RESULTS: (1) During surgery, the patients' SBP and HR of both sham and EA groups were increased significantly compared with their basic values (P < 0.05), but the levels of the increased SBP and HR of the EA group were obviously lower than those of the sham group (P < 0.05). (2) The levels of plasma ACTH during surgery and at the immediate time after surgery, Cor level at the immediate time after surgery, plasma E and Glu contents during surgery, at the immediate time and on day 1 after surgery, and plasma CRP at the immediate time, and on day 1 and 3 after surgery in the sham group were upregulated considerably (P < 0.05), while the levels of plasma ACTH, Cor, E, Glu and CRP in the above-mentioned time-points of the EA group were all remarkably lower than those of the sham group (P < 0.05). CONCLUSION: EA combined with cervical plexus block significantly reduces peri-operative cardiovascular stress responses and inhibits abnormal increases of plasma stress hormones and inflammatory reaction in patients undergoing thyroid surgery.


Asunto(s)
Analgesia por Acupuntura , Plexo Cervical/efectos de los fármacos , Electroacupuntura , Bloqueo Nervioso , Enfermedades de la Tiroides/fisiopatología , Enfermedades de la Tiroides/cirugía , Puntos de Acupuntura , Hormona Adrenocorticotrópica/metabolismo , Adulto , Presión Sanguínea , Proteína C-Reactiva/metabolismo , Plexo Cervical/metabolismo , Plexo Cervical/fisiopatología , Femenino , Frecuencia Cardíaca , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven
9.
Rinsho Shinkeigaku ; 53(4): 299-303, 2013.
Artículo en Japonés | MEDLINE | ID: mdl-23603545

RESUMEN

A 69-year-old woman complained of diplopia and truncal titubation after upper respiratory infection. She presented with mydriasis and external opthalmoplegia of bilateral eyes, ataxia, hyporeflexia and cervical-brachial muscle weakness. The protein abnormally increased (49 mg/dl) in the cerebrospinal fluid, and the serum anti-GQ1b and anti-GT1a IgG antibodies were positive. The blood sodium level was 128 mmol/l indicating hyponatremia. She had low plasma osmolarity (251 mOsm/kg), high urine osmolarity (357 mOsm/kg) and high urine sodium level (129 mmol/l), while the blood level of antidiuretic hormone was not able to be measured. She was diagnosed to have Fisher syndrome (FS), pharyngeal-cervical-brachial variant of Guillain-Barré syndrome (PCB) and syndrome of inappropriate secretion of antidiuretic hormone (SIADH). The hyponatremia improved with hyperosmotic saline infusion and restriction of water intake. Intravenous immunoglobulin therapy (IVIg) was effective only for ataxia, but the other symptoms mostly remained unchanged for a month. The serum anti-GQ1b IgG antibody was still positive even after one month. We performed high-dose intravenous steroid-pulse therapy. Then the mydriasis, external opthalmoplegia and cervical-brachial muscle weakness were immediately improved. This was a rare case of FS and PCB complicated with SIADH. IVIg, not steroid therapy, is generally chosen for FS since FS is considered as a variant of Guillain-Barré syndrome and steroid is not effective for Guillain-Barré syndrome as was proven by double-blind study. We suppose that the combined therapy of IVIg and steroid would be effective in patients with complicated symptoms and multiple antibodies.


Asunto(s)
Síndrome de Guillain-Barré/complicaciones , Síndrome de Secreción Inadecuada de ADH/etiología , Síndrome de Miller Fisher/complicaciones , Anciano , Plexo Braquial/fisiopatología , Plexo Cervical/fisiopatología , Femenino , Síndrome de Guillain-Barré/fisiopatología , Humanos , Músculos Faríngeos/inervación
10.
Cancer Radiother ; 17(1): 44-9, 2013 Feb.
Artículo en Francés | MEDLINE | ID: mdl-23219138

RESUMEN

The authors report a case of Dropped Head Syndrome with an unusually rapid onset after an accident in a patient with a history of Hodgkin's lymphoma cured by chemotherapy and mantle field radiotherapy and compare this case to the rare published cases of chronic Dropped Head Syndrome occurring after this type of treatment. A 56-year-old man was treated at the age 36 years for supra-diaphragmatic Hodgkin's lymphoma by chemotherapy and mantle field radiotherapy according to a standard technique and standard doses (40Gy, 20 fractions, 27 days). Seventeen years after the end of treatment, he experienced a violent whiplash injury, rapidly followed by a Dropped Head Syndrome, similar to the cases of chronic Dropped Head Syndrome already described in the context of Hodgkin's lymphoma (permanent flexion of the head, only reduced in the supine position). Physical and neurophysiological examination, electromyogram, and magnetic resonance imaging confirmed the diagnosis of Dropped Head Syndrome. Very few treatment options are available for the major disability related to Dropped Head Syndrome. This type of subacute onset of Dropped Head Syndrome has not been previously described. The good results of radiation therapy after chemotherapy allow a dose reduction to 30Gy in the involved regions. This, together with recent progress in treatment planning, should allow eradication of these complications.


Asunto(s)
Plexo Cervical/efectos de la radiación , Enfermedad de Hodgkin/radioterapia , Debilidad Muscular/etiología , Músculos del Cuello/inervación , Traumatismos por Radiación/etiología , Radioterapia de Alta Energía/efectos adversos , Lesiones por Latigazo Cervical/complicaciones , Accidentes de Tránsito , Protocolos de Quimioterapia Combinada Antineoplásica/administración & dosificación , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Bleomicina/administración & dosificación , Plexo Cervical/lesiones , Plexo Cervical/fisiopatología , Vértebras Cervicales , Terapia Combinada , Dacarbazina/administración & dosificación , Fraccionamiento de la Dosis de Radiación , Doxorrubicina/administración & dosificación , Electromiografía , Enfermedad de Hodgkin/complicaciones , Enfermedad de Hodgkin/tratamiento farmacológico , Humanos , Imagen por Resonancia Magnética , Masculino , Mecloretamina/administración & dosificación , Persona de Mediana Edad , Debilidad Muscular/fisiopatología , Músculos del Cuello/fisiopatología , Osteoartritis/complicaciones , Prednisona/administración & dosificación , Procarbazina/administración & dosificación , Traumatismos por Radiación/fisiopatología , Dosificación Radioterapéutica , Inducción de Remisión , Vinblastina/administración & dosificación , Vincristina/administración & dosificación
11.
Anesteziol Reanimatol ; (3): 22-5, 2012.
Artículo en Ruso | MEDLINE | ID: mdl-22993918

RESUMEN

MATERIALS AND METHODS: 77 anaesthesia protocols during a. carotis interna (ACI) operations were analyzed. All the patients were divided into 3 groups. In the 1-st group a total intravenous anaesthesia - TIV4 (propofol and fentanyl) was used. In the 2nd and 3rd groups was used combined anaesthesia: in the 2nd - TIVA + superficial CPB, in the 3rd - combined anesthesia (sevortane+fentanyl+CPB). When analyzing the results, BP, BIS data, anaesthetic doses and the need for opioid analgesics were evaluated. Assessment of the postoperative pain quality was conducted within 48 hours of the postoperative period on a verbal assessment scale (VAS). RESULTS: The need for fentanyl was considerably higher in the 1st group. The analysis of the BP data dynamics showed better stability in the 2nd and 3rd groups. CONCLUSIONS: TIVA + CPB provides better analgesia and reduces the need for opioid analgesics; greater stability of hemodynamic parameters during operation stages, as well as the best brain perfusion during a. carotis interna occlusion; postoperative analgesia and allows to avoid the early appointment of systemic analgesics.


Asunto(s)
Anestesia Intravenosa/métodos , Anestésicos Combinados , Arteria Carótida Interna/cirugía , Plexo Cervical/fisiopatología , Bloqueo Nervioso/métodos , Dolor Postoperatorio/prevención & control , Terapia Combinada , Relación Dosis-Respuesta a Droga , Femenino , Hemodinámica/efectos de los fármacos , Humanos , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Satisfacción del Paciente , Resultado del Tratamiento
12.
Rev Neurol ; 54 Suppl 2: S39-50, 2012 Apr 10.
Artículo en Español | MEDLINE | ID: mdl-22532242

RESUMEN

INTRODUCTION. Chronic migraine is the most frequent complication of migraine. Its management is complex and difficult, and is based essentially on preventive measures. AIM. To analyse the development of the use of Onabotulinumtoxin A (OnabotA) in migraine, especially in its chronic form, the method of administration, its mechanism of action, its safety profile and its possible indications in clinical practice. DEVELOPMENT. The study conducts a thorough review of all the clinical trials in the literature that have used OnabotA in the prevention of migraine, both in its episodic and its chronic forms, and the outcomes in the chronic form are analysed in detail. CONCLUSIONS. In studies in phase III, OnabotA has proved to be effective in the treatment of patients with chronic migraine, with significant reductions in the mean frequency of days with headaches, the number of headache episodes, the days with migraine or the proportion of patients with severe disability, in addition to other parameters. It is also effective in the subgroup of patients with symptomatic headache due to medication abuse. OnabotA has proved to be safe and well tolerated in this indication, with foreseeable, usually mild or moderate, transitory side effects. In sum, OnabotA is a safe, well-tolerated alternative in the preventive treatment of chronic migraine.


Asunto(s)
Toxinas Botulínicas Tipo A/uso terapéutico , Trastornos Migrañosos/tratamiento farmacológico , Acetilcolina/metabolismo , Toxinas Botulínicas Tipo A/administración & dosificación , Toxinas Botulínicas Tipo A/efectos adversos , Toxinas Botulínicas Tipo A/farmacología , Plexo Cervical/fisiopatología , Enfermedad Crónica , Ensayos Clínicos como Asunto , Método Doble Ciego , Cefaleas Secundarias/etiología , Cefaleas Secundarias/prevención & control , Humanos , Inyecciones Intramusculares , Estudios Multicéntricos como Asunto , Debilidad Muscular/inducido químicamente , Bloqueo Neuromuscular , Selección de Paciente , Ensayos Clínicos Controlados Aleatorios como Asunto , Simpatectomía Química , Proteína 25 Asociada a Sinaptosomas/antagonistas & inhibidores , Resultado del Tratamiento , Nervio Trigémino/fisiopatología
13.
Anesth Analg ; 109(6): 2008-11, 2009 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-19923533

RESUMEN

BACKGROUND: Interscalene brachial plexus block (ISB) using the modified lateral approach provides a well-established method of anesthesia and analgesia for patients undergoing shoulder surgery. Considering the neural anatomy at the site of injection, the superficial cervical plexus may be at risk of injury. We evaluated the incidence and characteristics of superficial cervical plexus neuropathy. METHODS: During a 1-yr period, 273 consecutive patients requiring single-injection ISB for shoulder or proximal arm surgery were studied. Patients were examined for symptoms compatible with superficial cervical plexus injury before surgery, 24 h postoperatively, and contacted by telephone 31 days after surgery. Symptomatic patients received an additional phone call 6 mo after surgery. RESULTS: Twenty-four hours after shoulder surgery, 21 patients (7.7%) showed symptoms consistent with superficial cervical plexus neuropathy. Symptoms consisted of hypesthesia in 1-4 cutaneous branches of the cervical plexus. Five patients (1.8%) reported symptoms that lasted for >31 days. All symptoms had entirely resolved after 6 mo. CONCLUSIONS: Superficial cervical plexus neuropathy is not uncommon after ISB using the modified lateral approach and the possibility should be discussed with patients preprocedurally.


Asunto(s)
Anestésicos Locales/administración & dosificación , Plexo Braquial , Plexo Cervical/lesiones , Hipoestesia/etiología , Bloqueo Nervioso/efectos adversos , Adulto , Brazo/cirugía , Plexo Cervical/fisiopatología , Femenino , Humanos , Hipoestesia/fisiopatología , Inyecciones/efectos adversos , Masculino , Persona de Mediana Edad , Hombro/cirugía , Factores de Tiempo
14.
Headache ; 49(5): 726-31, 2009 May.
Artículo en Inglés | MEDLINE | ID: mdl-18783446

RESUMEN

OBJECTIVE: To contrast the cervical range of motion (CROM) in women with episodic migraine (EM), transformed migraine (TM), and controls without migraine headaches. BACKGROUND: Migraineurs often complain about neck pain. Furthermore, neck problems can worsen the headaches in individuals with migraine. Individuals with neck pain usually have reduced CROM. Nonetheless, studies assessing the CROM in migraineurs are scarce. METHODS: Our sample was selected in an outpatient headache clinic, and consisted of 45 women aged 20-54 years old, 15 per group. Cervical mobility was evaluated in movements of flexion, extension, right lateral flexion, left lateral flexion, right rotation, and left rotation using the CROM technique, and was contrasted among the groups. Migraine clinical patterns were also evaluated (frequency, duration of migraine, pain in the moment of evaluation, pain in movement, and pain localization) as a function of CROM. RESULTS: Compared with controls, individuals with TM had numerically inferior CROM in all parameters, and significant reduction in 3 of them: extension (59.3 vs 68.1, P = .02), left lateral flexion (44.5 vs 49.1, P = .03), and right rotation (62.2 vs 69.6, P = .02). Compared with individuals with migraine, the TM group presented significantly reduced mobility only for extension (59.3 vs 68.4, P = .02). Migraineurs also had numerically inferior ROM, contrasted to controls, in 5 of the 6 parameters, although significance was seen just for right rotation (60.8 vs 68.6 P < .01). There was no correlation between cervical mobility and migraine parameters. The CROM was not reduced for the symptomatic side of migraine, in cases of unilateral pain. CONCLUSION: Contrasted to controls, individuals with episodic and TM have decreased cervical range of motion.


Asunto(s)
Vértebras Cervicales/fisiopatología , Trastornos Migrañosos/diagnóstico , Trastornos Migrañosos/epidemiología , Dolor de Cuello/diagnóstico , Dolor de Cuello/epidemiología , Rango del Movimiento Articular/fisiología , Adulto , Plexo Cervical/fisiopatología , Comorbilidad , Evaluación de la Discapacidad , Femenino , Movimientos de la Cabeza/fisiología , Humanos , Persona de Mediana Edad , Trastornos Migrañosos/fisiopatología , Músculos del Cuello/fisiopatología , Dolor de Cuello/fisiopatología , Variaciones Dependientes del Observador , Dimensión del Dolor/métodos , Proyectos Piloto , Valor Predictivo de las Pruebas , Sensibilidad y Especificidad , Núcleo Caudal del Trigémino/fisiopatología , Nervio Trigémino/fisiopatología , Adulto Joven , Articulación Cigapofisaria/fisiopatología
15.
Pain Physician ; 11(6): 849-54, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-19057630

RESUMEN

BACKGROUND: Cervicogenic headache descriptors include its unilateral nature, "signs and symptoms linking it to the neck," and trauma of the neck. Since the pain often occurs over the C2 or C3 nerve root, we used a modification of the deep cervical block technique for treatment of this refractory type headache. OBJECTIVE: To determine the efficacy of a modified deep cervical block for treatment of cervicogenic headache. DESIGN: Prospective case study. METHODS: Thirty-nine patients referred to our pain clinic participated in this study. All patients had undergone extensive screening/diagnostic testing. The blocks were performed unilaterally, without inducing a risk of invading the neural foramen, and repeat injection of the contra-lateral side occurred at >1 week after initial injection. Patients were followed for a 6-month period using a pain diary and questionnaire. Pain was assessed pre- and post-injection and 3 and 6 months post treatments. RESULTS: The mean treatment period was 59 +/- 61 days. The mean values for pre- and post-injection series pain scores (0-10 pain scale) were 9.54 +/- 1.53 and 6.75 +/- 3.23 respectively (p <0.001). Thirty-three percent (33%) of the patients reported pain scores of < or = 4 on the 0-10 pain scale after their last treatment. Effectiveness of the therapy following the injection procedure was rated to be 42% effective for all first injections and 40% effective for last injections (p =NS). Six months evaluations showed that return of moderate to severe pain took 6.62 +/- 8.1 weeks. At the 3 and 6 months follow up evaluations, mean pain scores had returned to 8.41 +/- 2.96 and 8.83 +/- 2.78, respectively. Ten patients (24%) had pain scores < or = 4 at the 3-month evaluation while 7 of the patients (18%) had pain scores < or = 4 at the 6-month evaluation. CONCLUSIONS: These results showed that for some patients this series of blocks provided effective pain relief for 3 months post treatment but by 6 months the pain had returned to pre-treatment levels. This block technique significantly diminished pain after the initial as well as the last treatment. These clinically significant changes in pain relief suggest that more aggressive selective therapy targeting these nerve routes might provide longer lasting relief.


Asunto(s)
Plexo Cervical/efectos de los fármacos , Bloqueo Nervioso/métodos , Bloqueo Nervioso/estadística & datos numéricos , Cefalea Postraumática/tratamiento farmacológico , Radiculopatía/tratamiento farmacológico , Adulto , Anciano , Anestésicos Locales/administración & dosificación , Plexo Cervical/fisiopatología , Vértebras Cervicales/diagnóstico por imagen , Vértebras Cervicales/patología , Vértebras Cervicales/fisiopatología , Enfermedad Crónica/tratamiento farmacológico , Femenino , Fluoroscopía , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Cefalea Postraumática/patología , Cefalea Postraumática/fisiopatología , Estudios Prospectivos , Radiculopatía/fisiopatología , Esteroides/administración & dosificación , Encuestas y Cuestionarios , Tiempo , Resultado del Tratamiento , Adulto Joven
16.
Recenti Prog Med ; 99(6): 295-301, 2008 Jun.
Artículo en Italiano | MEDLINE | ID: mdl-18710060

RESUMEN

UNLABELLED: Occipital neuralgia is characterized by pain paroxysm occurring within distribution of the greater or lesser occipital nerves. The pain may radiates from the rear head toward the ipso-lateral frontal or retro-orbital regions of head. Though known causes include head injuries, direct occipital nerve trauma, neuroma formation or upper cervical root compression, most people have no demonstrable lesion. METHOD AND MATERIALS: A sample of 8 patients (5 females, 3 males) aging 63,5 years on the average with occipital neuralgia has been recruited. The occipital neuralgic pain had presented since 4, 6 years and they had been treated by pharmacological therapy without benefit. Some result has been obtained by blocking of the grand occipital nerve so that the patients seemed to be suitable for subcutaneous peripheral neurostimulation. The pain was evaluated by VAS and SVR scales before treatment (TO) and after three and twelve months (T1, T2). RESULTS: During the follow up period 7 patients have been monitored for a whole year while one patient was followed only for 3 months in that some complications have presented. In the other 7 patients pain paroxysms have interrupted and trigger point disappeared with a VAS and SVR reduction of about 71% and 60%, respectively. CONCLUSIONS: Our experience demonstrates a sound efficacy of such a technique for patients having occipital neuralgia resistant to pharmacological therapies even if action mechanisms have not yet clearly explained. Some hypothesis exist and we think it might negatively affect the neurogenic inflammation that surely acts in pain maintaining.


Asunto(s)
Plexo Cervical/fisiopatología , Neuralgia/terapia , Hueso Occipital/inervación , Dolor Intratable/terapia , Estimulación Eléctrica Transcutánea del Nervio/métodos , Anciano , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Dimensión del Dolor/métodos , Estudios Retrospectivos , Resultado del Tratamiento
17.
J Surg Oncol ; 98(3): 200-1, 2008 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-18537152

RESUMEN

In an effort to overcome shoulder morbidity from the classical radical neck dissection, modifications preserving the entire spinal accessory nerve, were described. When there are metastatic upper jugular nodes with potential extracapsular spread, modifications that preserve the entire XI nerve may be oncologically unsafe. We describe a technique wherein the XI nerve is preserved based on the contribution from the cervical plexus, while allowing resection of the proximal part of the nerve en bloc with the specimen. This modification may preserve useful trapezius function without compromising oncological safety.


Asunto(s)
Nervio Accesorio/fisiopatología , Plexo Cervical/fisiopatología , Neoplasias de Cabeza y Cuello/cirugía , Disección del Cuello , Nervio Accesorio/cirugía , Neoplasias de Cabeza y Cuello/patología , Humanos
18.
Tumori ; 94(1): 36-9, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-18468333

RESUMEN

AIMS AND BACKGROUND: The aim of this study is to determine the effects of two different types of nerve-sparing neck dissection on shoulder function. Even if the spinal accessory nerve is spared in functional neck dissection, some degree of shoulder syndrome may occur. The role of the cervical plexus in shoulder function and the effects of dissection of level 5 are emphasized. METHODS: Twenty-six patients with laryngeal carcinoma were studied prospectively. Seventeen anterolateral and 15 functional neck dissections were performed. Electromyographic evaluation was carried out in all patients to assess spinal accessory nerve function preoperatively and at the sixth week and sixth month postoperatively. Shoulder disability was evaluated by a questionnaire (shoulder pain disability index) and goniometric measurements were done preoperatively and at the sixth postoperative month. RESULTS: In patients who underwent anterolateral neck dissection, the goniometric results were better than in the functional neck dissection group. The questionnaire results also showed better quality of life of patients who underwent anterolateral neck dissection. Electrophysiological evaluation of the trapezius muscles of both groups at the sixth week showed significant differences. The distal motor latency values of the anterolateral neck dissection group were shorter than those of the other group. Electrophysiological evaluation at the sixth postoperative month showed shorter distal latency values in the anterolateral dissection group, without statistical significance. CONCLUSIONS: Preservation of the cervical plexus and less disturbance of the spinal accessory nerve are important to diminish postoperative shoulder disability. The type of neck dissection has an important influence on shoulder function.


Asunto(s)
Nervio Accesorio/fisiopatología , Plexo Cervical/fisiopatología , Neoplasias Laríngeas/cirugía , Disección del Cuello , Hombro/fisiopatología , Nervio Accesorio/cirugía , Plexo Cervical/cirugía , Electromiografía , Humanos , Dolor/etiología , Estudios Prospectivos , Encuestas y Cuestionarios
19.
Curr Pain Headache Rep ; 12(1): 62-6, 2008 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-18417026

RESUMEN

There is an unmet need, and thus a continued search, for effective treatments for patients with chronic daily headache who do not respond to or tolerate conventional therapies. Recent interest has focused on the use of occipital nerve stimulation (ONS) to treat patients with chronic, disabling headaches who are not adequately controlled by usual therapies. A small but growing body of evidence supports the use of ONS for the treatment of intractable headache. Electrical stimulation of the occipital nerve has both peripheral and central nervous system effects that modulate nociception. The exact role for ONS will evolve as our understandings of its physiologic effects, efficacy, and safety grow.


Asunto(s)
Plexo Cervical/fisiopatología , Terapia por Estimulación Eléctrica , Trastornos de Cefalalgia/fisiopatología , Trastornos de Cefalalgia/terapia , Cefalalgia Histamínica/terapia , Terapia por Estimulación Eléctrica/efectos adversos , Terapia por Estimulación Eléctrica/métodos , Humanos , Trastornos Migrañosos/terapia , Neuralgia/terapia , Resultado del Tratamiento
20.
J Neurosurg ; 107(6): 1235-7, 2007 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-18077965

RESUMEN

The authors report on their technique for preserving the lesser occipital nerve (LON) during lateral suboccipital craniotomy. In their technique, the LON, which runs along the surface of or just beneath the sternocleidomastoid muscle, is identified and preserved. Lesser occipital nerve preservation using their technique was attempted in 25 patients who underwent microvascular decompression for hemifacial spasm. The LON was successfully preserved in 16 of these patients, was impossible to preserve in two patients, and could not be identified in seven patients. Among the patients in whom LON preservation was successful, 87.5% were free of sensory disturbance 6 months after surgery, whereas both patients in whom the LON could not be preserved complained of sensory disturbances in the occipital area and the posterior part of the auricula. Fifty-seven percent of the patients whose LON could not be identified complained of sensory disturbance. Thus, this technique for preserving the LON reduces the incidence of sensory disturbance in the occipital region after suboccipital craniotomy for microvascular decompression for hemifacial spasm.


Asunto(s)
Descompresión Quirúrgica/métodos , Espasmo Hemifacial/cirugía , Microcirugia/métodos , Nervios Periféricos/fisiopatología , Plexo Cervical/fisiopatología , Oído Externo/inervación , Cara , Espasmo Hemifacial/fisiopatología , Humanos , Periodo Posoperatorio , Piel/inervación
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