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1.
Unfallchirurgie (Heidelb) ; 127(5): 391-402, 2024 May.
Article De | MEDLINE | ID: mdl-38619616

Head injuries are frequent occurrences in emergency departments worldwide and are notable for the fact that attention must be paid to the sequelae of intracranial and extracranial trauma. It is crucial to assess potential intracranial injuries and to strive for both medically sound and esthetically pleasing extracranial outcomes. The aim of this continuing education article is to provide a refresher on knowledge of head injuries and the associated nuances for wound care.


Craniocerebral Trauma , Humans , Craniocerebral Trauma/complications , Craniocerebral Trauma/surgery , Craniocerebral Trauma/therapy , Neurosurgery , Brain Injuries, Traumatic/therapy
2.
BMJ Open ; 14(4): e078622, 2024 Apr 03.
Article En | MEDLINE | ID: mdl-38569695

INTRODUCTION: Mild traumatic brain injury is common in children and it can be challenging to accurately identify those in need of urgent medical intervention. The Scandinavian guidelines for management of minor and moderate head trauma in children, the Scandinavian Neurotrauma Committee guideline 2016 (SNC16), were developed to aid in risk stratification and decision-making in Scandinavian emergency departments (EDs). This guideline has been validated externally with encouraging results, but internal validation in the intended healthcare system is warranted prior to broad clinical implementation. OBJECTIVE: We aim to validate the diagnostic accuracy of the SNC16 to predict clinically important intracranial injuries (CIII) in paediatric patients suffering from blunt head trauma, assessed in EDs in Sweden and Norway. METHODS AND ANALYSIS: This is a prospective, pragmatic, observational cohort study. Children (aged 0-17 years) with blunt head trauma, presenting with a Glasgow Coma Scale of 9-15 within 24 hours postinjury at an ED in 1 of the 16 participating hospitals, are eligible for inclusion. Included patients are assessed and managed according to the clinical management routines of each hospital. Data elements for risk stratification are collected in an electronic case report form by the examining doctor. The primary outcome is defined as CIII within 1 week of injury. Secondary outcomes of importance include traumatic CT findings, neurosurgery and 3-month outcome. Diagnostic accuracy of the SNC16 to predict endpoints will be assessed by point estimate and 95% CIs for sensitivity, specificity, likelihood ratio, negative predictive value and positive predictive value. ETHICS AND DISSEMINATION: The study is approved by the ethical board in both Sweden and Norway. Results from this validation will be published in scientific journals, and a tailored development and implementation process will follow if the SNC16 is found safe and effective. TRIAL REGISTRATION NUMBER: NCT05964764.


Brain Concussion , Craniocerebral Trauma , Child , Humans , Craniocerebral Trauma/diagnosis , Craniocerebral Trauma/therapy , Emergency Service, Hospital , Glasgow Coma Scale , Multicenter Studies as Topic , Observational Studies as Topic , Prospective Studies , Infant, Newborn , Infant , Child, Preschool , Adolescent , Validation Studies as Topic , Practice Guidelines as Topic
3.
BMJ Open Qual ; 13(2)2024 Apr 24.
Article En | MEDLINE | ID: mdl-38663928

INTRODUCTION: At Sandwell General Hospital, there was no risk stratification tool or pathway for head injury (HI) patients presenting to the emergency department (ED). This resulted in significant delays in the assessment of HI patients, compromising patient safety and quality of care. AIMS: To employ quality improvement methodology to design an effective adult HI pathway that: ensured >90% of high-risk HI patients being assessed by ED clinicians within 15 min of arrival, reduce CT turnaround times, and aiming to keep the final decision making <4 hours. METHODS: SWOT analysis was performed; driver diagrams were used to set out the aims and objectives. Plan-Do-Study-Act cycle was used to facilitate the change and monitor the outcomes. Process map was designed to identify the areas for improvement. A new HI pathway was introduced, imaging and transporting the patients was modified, and early decisions were made to meet the standards. RESULTS: Data were collected and monitored following the interventions. The new pathway improved the proportion of patients assessed by the ED doctors within 15 min from 31% to 63%. The average time to CT head scan was decreased from 69 min to 53 min. Average CT scan reporting time also improved from 98 min to 71 min. Overall, the average time to decision for admission or discharge decreased from 6 hours 48 min to 4 hours 24 min. CONCLUSIONS: Following implementation of the new HI pathway, an improvement in the patient safety and quality of care was noted. High-risk HI patients were picked up earlier, assessed quicker and had CT head scans performed sooner. Decision time for admission/discharge was improved. The HI pathway continues to be used and will be reviewed and re-audited between 3 and 6 months to ensure the sustained improvement.


Craniocerebral Trauma , Emergency Service, Hospital , Quality Improvement , Humans , Emergency Service, Hospital/organization & administration , Emergency Service, Hospital/statistics & numerical data , Craniocerebral Trauma/therapy , Adult , Tomography, X-Ray Computed/methods , Tomography, X-Ray Computed/statistics & numerical data , Tomography, X-Ray Computed/standards , Male , Female
4.
JAMA Netw Open ; 7(3): e242366, 2024 Mar 04.
Article En | MEDLINE | ID: mdl-38502126

Importance: Minor head trauma (HT) is one of the most common causes of hospitalization in children. A diagnostic test could prevent unnecessary hospitalizations and cranial computed tomographic (CCT) scans. Objective: To evaluate the effectiveness of serum S100B values in reducing exposure to CCT scans and in-hospital observation in children with minor HT. Design, Setting, and Participants: This multicenter, unblinded, prospective, interventional randomized clinical trial used a stepped-wedge cluster design to compare S100B biomonitoring and control groups at 11 centers in France. Participants included children and adolescents 16 years or younger (hereinafter referred to as children) admitted to the emergency department with minor HT. The enrollment period was November 1, 2016, to October 31, 2021, with a follow-up period of 1 month for each patient. Data were analyzed from March 7 to May 29, 2023, based on the modified intention-to-treat and per protocol populations. Interventions: Children in the control group had CCT scans or were hospitalized according to current recommendations. In the S100B biomonitoring group, blood sampling took place within 3 hours after minor HT, and management depended on serum S100B protein levels. If the S100B level was within the reference range according to age, the children were discharged from the emergency department. Otherwise, children were treated as in the control group. Main Outcomes and Measures: Proportion of CCT scans performed (absence or presence of CCT scan for each patient) in the 48 hours following minor HT. Results: A total of 2078 children were included: 926 in the control group and 1152 in the S100B biomonitoring group (1235 [59.4%] boys; median age, 3.2 [IQR, 1.0-8.5] years). Cranial CT scans were performed in 299 children (32.3%) in the control group and 112 (9.7%) in the S100B biomonitoring group. This difference of 23% (95% CI, 19%-26%) was not statistically significant (P = .44) due to an intraclass correlation coefficient of 0.32. A statistically significant 50% reduction in hospitalizations (95% CI, 47%-53%) was observed in the S100B biomonitoring group (479 [41.6%] vs 849 [91.7%]; P < .001). Conclusions and Relevance: In this randomized clinical trial of effectiveness of the serum S100B level in the management of pediatric minor HT, S100B biomonitoring yielded a reduction in the number of CCT scans and in-hospital observation when measured in accordance with the conditions defined by a clinical decision algorithm. Trial Registration: ClinicalTrials.gov Identifier: NCT02819778.


Craniocerebral Trauma , Hospitalization , Adolescent , Child , Child, Preschool , Female , Humans , Male , Algorithms , Biological Monitoring , Craniocerebral Trauma/diagnostic imaging , Craniocerebral Trauma/therapy , Prospective Studies , S100 Calcium Binding Protein beta Subunit , Infant
5.
BMJ Open ; 14(2): e078363, 2024 Feb 13.
Article En | MEDLINE | ID: mdl-38355171

OBJECTIVE: Hospital-based clinical decision tools support clinician decision-making when a child presents to the emergency department with a head injury, particularly regarding CT scanning. However, there is no decision tool to support prehospital clinicians in deciding which head-injured children can safely remain at scene. This study aims to identify clinical decision tools, or constituent elements, which may be adapted for use in prehospital care. DESIGN: Systematic mapping review and narrative synthesis. DATA SOURCES: Searches were conducted using MEDLINE, EMBASE, PsycINFO, CINAHL and AMED. ELIGIBILITY CRITERIA: Quantitative, qualitative, mixed-methods or systematic review research that included a clinical decision support tool for assessing and managing children with head injury. DATA EXTRACTION AND SYNTHESIS: We systematically identified all in-hospital clinical decision support tools and extracted from these the clinical criteria used in decision-making. We complemented this with a narrative synthesis. RESULTS: Following de-duplication, 887 articles were identified. After screening titles and abstracts, 710 articles were excluded, leaving 177 full-text articles. Of these, 95 were excluded, yielding 82 studies. A further 14 studies were identified in the literature after cross-checking, totalling 96 analysed studies. 25 relevant in-hospital clinical decision tools were identified, encompassing 67 different clinical criteria, which were grouped into 18 categories. CONCLUSION: Factors that should be considered for use in a clinical decision tool designed to support paramedics in the assessment and management of children with head injury are: signs of skull fracture; a large, boggy or non-frontal scalp haematoma neurological deficit; Glasgow Coma Score less than 15; prolonged or worsening headache; prolonged loss of consciousness; post-traumatic seizure; amnesia in older children; non-accidental injury; drug or alcohol use; and less than 1 year old. Clinical criteria that require further investigation include mechanism of injury, clotting impairment/anticoagulation, vertigo, length of time of unconsciousness and number of vomits.


Craniocerebral Trauma , Decision Support Systems, Clinical , Emergency Medical Services , Child , Humans , Infant , Paramedics , Craniocerebral Trauma/diagnosis , Craniocerebral Trauma/therapy , Hospitals
6.
Injury ; 55(3): 111299, 2024 Mar.
Article En | MEDLINE | ID: mdl-38199073

BACKGROUND: The purpose of this study is to characterize the effects of head injuries amongst the middle-aged and geriatric populations on hospital quality measures, costs, and outcomes in an orthopedic trauma setting. METHODS: Patients with head and orthopedic injuries aged >55 treated at an academic medical center from October 2014-April 2021 were reviewed for their Abbreviated Injury Score for Head and Neck (AIS-H), baseline demographics, injury characteristics, hospital quality measures and outcomes. Univariate comparative analyses were conducted across AIS-H groups with additional regression analyses controlling for confounding variables. All statistical analyses were conducted with a Bonferroni adjusted alpha. RESULTS: A total of 1,051 patients were included. The mean age was 74 years, and median AIS-H score was 2 (range 1-6). While outcomes worsened and costs increased as AIS-H scores increased, the most drastic (and clinically relevant) rise occurs between scores 2-3. Patients who sustained a head injury warranting an AIS-H score of 3 experienced a significantly higher rate of major complications, need for ICU admission, inpatient and 1-year mortality with longer lengths of stay and higher total costs despite no differences in demographics or injury characteristics. Regression analysis found a higher AIS-H score was independently associated with greater mortality risk. CONCLUSION: AIS-H scores >2 correlate with significantly worse outcomes and higher hospital costs. Concomitant head injuries impact both outcomes and direct variable costs for middle-aged and geriatric orthopedic trauma patients. Clinicians, hospitals, and payers should consider the significant effect of head injuries on the hospitalization of these patients.


Craniocerebral Trauma , Hospitalization , Middle Aged , Humans , Aged , Injury Severity Score , Craniocerebral Trauma/therapy , Hospitals , Costs and Cost Analysis
7.
Injury ; 55(3): 111181, 2024 Mar.
Article En | MEDLINE | ID: mdl-37951809

BACKGROUND: Head trauma is a leading cause of death and disability worldwide. Young males, Indigenous people, and rural/remote residents have been identified as high-risk populations for head trauma, however, Australian research is limited. Our aim was to define and describe the incidence, demographics, causes, prehospital interventions, and outcomes of head trauma patients transported by aeromedical services within North Queensland, Australia. We hypothesized that young, Indigenous males living remotely would be disproportionately affected by head trauma. METHODS: We conducted a retrospective study of all head trauma patients transferred by air to or between Townsville, Cairns, Mount Isa and Mackay Hospitals between January 1, 2016 and December 31, 2018. Patients were identified from the Trauma Care in the Tropics data registry and followed for a median 30-months post-injury. Primary endpoints were patient and injury characteristics. Secondary outcome measures were hospital stay and mortality. RESULTS: A total of 981 patients were included and 31.1 % were Indigenous. Sixty-seven percent of injuries occurred remotely and the median time from injury to hospital was 5.8-hours (range 67-3780 min). Eighty percent of severe head injuries occurred in males (p = 0.007). Indigenous and remote patients were more likely to sustain mild injuries. The most common mechanism of injury overall was vehicle accident (37.5 %), compared to assault in the Indigenous subgroup (46.6 %, p<0.001). The overall mortality rate was 4.9 %, with older age and lower initial Glasgow Coma Score significant predictors of in-hospital mortality. Prehospital intubation was associated with a 7-fold increased risk of mortality (p = 0.056), while patients that received tranexamic acid (TXA) were almost 5-times more likely to die. CONCLUSIONS: In North Queensland, young Indigenous males are at highest risk of traumatic head injuries. Vehicle accidents are an important preventable cause of head injury in the region. TXA administration is an important consideration for remote head trauma retrievals, in which time to emergency care is prolonged. Appropriate treatment and risk stratification strategies considering time to definitive care, severity of injury, and other prehospital patient factors require further investigation.


Craniocerebral Trauma , Tranexamic Acid , Male , Humans , Queensland/epidemiology , Retrospective Studies , Australia , Craniocerebral Trauma/epidemiology , Craniocerebral Trauma/therapy
8.
Klin Padiatr ; 236(1): 11-15, 2024 Jan.
Article En | MEDLINE | ID: mdl-37816378

BACKGROUND: Minor head trauma is a common reason for emergency department visits in children, but many of these cases are not clinically significant. Despite established criteria for selecting patients who require computed tomography (CT), concerns about overuse of CT persist. This study aimed to determine the frequency of clinically important traumatic brain injury by retrospectively evaluating cranial CT scans in children categorized as very low risk for such injuries based on PECARN prediction rules. MATERIALS AND METHODS: Cranial CT scans of 941 minor head trauma cases were assessed for the presence, type, and number of calvarial bone fractures. Concomitant bleeding and treatment approaches were also recorded. RESULTS: Among 881 patients (93.6%), cranial CT scans did not reveal any lesions apart from soft tissue edema. None of the cases had clinically important traumatic brain injury or required neurosurgical intervention. DISCUSSION AND CONCLUSION: The study demonstrated that 93.6% of cranial CT scans for pediatric minor head trauma were negative, indicating a concerningly high rate of CT overuse. Although prediction rules exist, their application in clinical practice is not always optimal. Given the principle of "first, do no harm," proper patient selection is crucial to avoid unnecessary exposure to ionizing radiation.


Brain Injuries, Traumatic , Craniocerebral Trauma , Child , Humans , Retrospective Studies , Craniocerebral Trauma/diagnostic imaging , Craniocerebral Trauma/therapy , Emergency Service, Hospital , Tomography, X-Ray Computed
9.
Scand J Trauma Resusc Emerg Med ; 31(1): 65, 2023 Oct 31.
Article En | MEDLINE | ID: mdl-37908011

OBJECTIVE: Most older adults with traumatic brain injuries (TBI) reach the emergency department via the ambulance service. Older adults, often with mild TBI symptoms, risk being under-triaged and facing poor outcomes. This study aimed to identify whether sufficient information is available on the scene to an ambulance clinician to identify an older adult at risk of an intracranial haemorrhage following a head injury. METHODS: This was a retrospective case-control observational study involving one regional ambulance service in the UK and eight emergency departments. 3545 patients aged 60 years and over presented to one regional ambulance service with a head injury between the 1st of January 2020 and the 31st of December 2020. The primary outcome was an acute intracranial haemorrhage on head computed tomography (CT) scan in patients conveyed to the emergency department (ED). A secondary outcome was factors associated with conveyance to the ED by the ambulance clinician. RESULTS: In 2020, 2111 patients were conveyed to the ED and 162 patients were found to have an intracranial haemorrhage on their head CT scan. Falls from more than 2 m (adjusted odds ratio (aOR) 3.45, 95% CI 1.78-6.40), chronic kidney disease (CKD) (aOR 2.80, 95% CI 1.25-5.75) and Clopidogrel (aOR 1.98, 95% CI 1.04-3.59) were associated with an intracranial haemorrhage. Conveyance to the ED was associated with patients taking anticoagulant and antiplatelet medication or a visible head injury or head injury symptoms. CONCLUSION: This study highlights that while most older adults with a head injury are conveyed to the ED, only a minority will have an intracranial haemorrhage following their head injury. While mechanisms of injury such as falls from more than 2 m remain a predictor, this work highlights that Clopidogrel and CKD are also associated with an increased odds of tICH in older adults following a head injury. These findings may warrant a review of current ambulance head injury guidelines.


Craniocerebral Trauma , Renal Insufficiency, Chronic , Aged , Humans , Middle Aged , Ambulances , Case-Control Studies , Clopidogrel , Craniocerebral Trauma/complications , Craniocerebral Trauma/therapy , Emergency Service, Hospital , Intracranial Hemorrhages/etiology , Intracranial Hemorrhages/complications , Observational Studies as Topic , Renal Insufficiency, Chronic/complications , Retrospective Studies
10.
No Shinkei Geka ; 51(6): 1000-1008, 2023 Nov.
Article Ja | MEDLINE | ID: mdl-38011874

Head trauma is a common neurosurgical complication. It is encountered daily at neurosurgical outpatient departments or after-hour emergency outpatient departments. In addition, most cases of patients with trauma transported by ambulance involve those with head trauma. Head trauma is a common and unavoidable neurosurgical injury. In case of a head injury, the neurosurgeon should verify the level of consciousness and perform a proper neurological examination. A head computed tomography should be performed immediately for any abnormalities. However, currently, severe trauma is often complicated by head trauma and various other injuries. When medical examinations and treatments focus only on head trauma, preventable trauma death cannot be avoided. Functional prognosis due to secondary brain injury may be exacerbated. This article presents a standardized procedure for the initial care of patients with multiple trauma and head injuries.


Brain Injuries , Craniocerebral Trauma , Multiple Trauma , Humans , Craniocerebral Trauma/complications , Craniocerebral Trauma/therapy , Craniocerebral Trauma/diagnosis , Emergency Service, Hospital , Head , Multiple Trauma/diagnosis , Multiple Trauma/therapy
11.
Ugeskr Laeger ; 185(34)2023 08 21.
Article Da | MEDLINE | ID: mdl-37622606

In Denmark, head injuries are generally managed according to the Scandinavian Neurotrauma Committee Guideline (SNC), which aims to safely reduce head CTs. This review investigates how pre-injury vitamin K-antagonist treatment is associated with adverse outcome in head injury patients, but the significance of other antithrombotics is uncertain. Implementation of S100B in the SNC Guideline has reduced CT usage by approx. 30%. However, S100B could likely be used in a wider array of patients. Despite its usefulness, S100B's popularity is still hampered, likely due to poor practical implementation in Danish emergency rooms.


Craniocerebral Trauma , Humans , Craniocerebral Trauma/complications , Craniocerebral Trauma/therapy , Biomarkers , Risk Assessment , Anticoagulants , Emergency Service, Hospital
13.
Clin Sports Med ; 42(3): 473-489, 2023 Jul.
Article En | MEDLINE | ID: mdl-37208060

Head injuries are a common occurrence in sports and can involve injuries to the brain, skull, and superficial soft tissues. The most commonly discussed diagnosis is a concussion. Head and cervical spine injuries must be considered together at times, due to the overlapping nature of symptoms present during on-field evaluation. This article presents a range of head injuries, along with critical steps in evaluation and management.


Athletic Injuries , Brain Concussion , Craniocerebral Trauma , Sports , Humans , Athletic Injuries/diagnosis , Athletic Injuries/epidemiology , Athletic Injuries/therapy , Emergencies , Craniocerebral Trauma/diagnosis , Craniocerebral Trauma/therapy , Brain Concussion/diagnosis , Brain Concussion/epidemiology , Brain Concussion/therapy
14.
Sportverletz Sportschaden ; 37(2): 96-99, 2023 06.
Article En | MEDLINE | ID: mdl-37216937

The COVID-19 (coronavirus disease 2019) pandemic forces athletes to perform their workout at home with alternative training methods. Exercise resistance bands, often used for this purpose, can cause damage when they recoil or tear. Potentially resulting injuries include bruises, head injuries, lacerations, facial fractures and eye injuries. The following article presents two case reports including accident mechanism, injuries, diagnostic evaluation and treatment.The first patient presented with an open depressed skull fracture caused by a recoiling exercise resistance band, while the second patient sustained a complex ocular trauma caused by a tearing exercise resistance band when performing supported chin-ups.


COVID-19 , Craniocerebral Trauma , Eye Injuries , Skull Fractures , Humans , Communicable Disease Control , Craniocerebral Trauma/etiology , Craniocerebral Trauma/therapy
15.
Londres; NICE; May 18, 2023. 74 p.
Non-conventional En | BIGG | ID: biblio-1434613

This guideline covers assessment and early management of head injury in babies, children, young people and adults. It aims to ensure that people have the right care for the severity of their head injury, including direct referral to specialist care if needed.


Humans , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Ambulatory Care/standards , Telemonitoring , Craniocerebral Trauma/therapy , Tranexamic Acid/therapeutic use , Tomography, X-Ray Computed , Craniocerebral Trauma/diagnostic imaging
16.
Am Surg ; 89(7): 3187-3191, 2023 Jul.
Article En | MEDLINE | ID: mdl-36803093

BACKGROUND: Guidelines developed by the Pediatric Emergency Care Applied Research Network (PECARN) exist to reserve the use of head CT for pediatric patients with a high risk of head injury. However, CTs are still being overutilized especially at adult trauma centers. The aim of our study was to review our use of head CTs in adolescent blunt trauma patients. MATERIALS AND METHODS: Patients aged 11-18 who underwent head CT scans from 2016 to 2019 at our urban level 1 adult trauma center were included. Data was collected via electronic medical record and analyzed through retrospective chart review. RESULTS: Of the 285 patients requiring a head CT, 205 had a negative head CT (NHCT) and 80 patients had a positive head CT (PHCT). There was no difference in age, gender, race, and trauma mechanism between the groups. The PHCT group was found to be with a statistically significant higher likelihood of the Glasgow Coma Scale (GCS) < 15 (65% vs 23%; P < .01), abnormal head exam (70% vs 25%; P < .01), and loss of consciousness (85% vs 54%; P < .01) compared to the NHCT group. There were 44 patients who had low risk of head injury, based on the PECARN guidelines, and received a head CT. None of the patients had a positive head CT. CONCLUSION: Our study suggests that reinforcement of the PECARN guidelines should occur for ordering head CTs in adolescent blunt trauma patients. Future prospective studies are needed to validate the use of PECARN head CT guidelines in this patient population.


Craniocerebral Trauma , Wounds, Nonpenetrating , Child , Humans , Adolescent , Adult , Trauma Centers , Retrospective Studies , Craniocerebral Trauma/therapy , Wounds, Nonpenetrating/diagnostic imaging , Glasgow Coma Scale , Tomography, X-Ray Computed , Emergency Service, Hospital
17.
An Pediatr (Engl Ed) ; 98(2): 83-91, 2023 Feb.
Article En | MEDLINE | ID: mdl-36754719

INTRODUCTION: In the assessment of infants younger than 3 months with minor traumatic head injury (MHI), it is essential to adapt the indication of imaging tests. The Pediatric Head Injury/Trauma Algorithm (PECARN) clinical prediction rule is the most widely used to guide clinical decision making. OBJECTIVES: To analyse the variability in the performance of imaging tests in infants under 3 months with MHI in paediatric emergency departments (PEDs) and the adherence of each hospital to the recommendations of the PECARN rule. POPULATION AND METHODS: We conducted a prospective multicentre observational study in 13 paediatric emergency departments in Spain between May 2017 and November 2020. RESULTS: Of 21 981 children with MHI, 366 (1.7%) were aged less than 3 months; 195 (53.3%) underwent neuroimaging, with performance of CT scans in 37 (10.1%; interhospital range, 0%-40.0%), skull X-rays in 162 (44.3 %; range, 0%-100%) and transfontanellar ultrasound scans in 22 (6.0%; range, 0%-24.0%). The established recommendations were followed in 25.6% (10/39) of infants classified as high-risk based on PECARN criteria (range, 0%-100%); 37.1% (36/97) classified as intermediate-risk (range, 0%-100%) and 57.4% (132/230) classified as low-risk (range, 0%-100%). CONCLUSION: We found substantial variability and low adherence to the PECARN recommendations in the performance of imaging tests in infants aged less than 3 months with MHI in Spanish PEDs, mainly due to an excessive use of skull X-rays.


Craniocerebral Trauma , Decision Support Techniques , Humans , Child , Infant , Craniocerebral Trauma/diagnostic imaging , Craniocerebral Trauma/therapy , Emergency Service, Hospital , Tomography, X-Ray Computed , Algorithms
18.
Scand J Trauma Resusc Emerg Med ; 31(1): 3, 2023 Jan 10.
Article En | MEDLINE | ID: mdl-36624501

BACKGROUND: The Scandinavian Neurotrauma Committee (SNC) has recommended the use of serum S100B as a biomarker for mild low-risk Traumatic brain injuries (TBI). This study aimed to assess the adherence to the SNC guidelines in clinical practice and the diagnostic performance of S100B in patients with TBI. The aims of this study were to examine adherence to the SNC guideline and the diagnostic accuracy of serum protein S100B. METHODS: Data of consecutive patients of 18 years and above who presented to the emergency department (ED) at Helsingborg Hospital with isolated head injuries, were retrieved from hospital records. Patients with multitrauma, follow-up visits, and visits managed by a nurse without physician involvement were excluded. RESULTS: A total of 1671 patients were included of which 93 (5.6%) had intracranial hemorrhage. CT scans were performed in 62% of patients. S100B was measured in 26% of patients and 30% of all measurements targeted the low-risk mild head injuries indicated by the guideline. S100B's recommended cut-off value (≥ 0.10 µg/L) had a 100% sensitivity, 47% specificity, 10.1% positive predictive value, and 100% negative predictive value-if applied to the target SNC category (SNC 4). If applied to all patients tested, the sensitivity was 93% for traumatic intracranial hemorrhage (TICH). Current ED practices were adherent to the SNC guideline in 55% of patients. Non-adherent practices occurred in 64% of patients with low-risk mild head injuries (SNC4) including overtesting or undertesting of S100B and CT scans. CONCLUSION: Adherence to guidelines was low and associated with a higher admission rate than non-adherence practice but no significant increase in missed TICH or death associated with non-adherence to guideline was found. In routine care, we found that the sensitivity and NPV of serum protein S100B was excellent and safely ruled out TICH when measured in the patient category recommended by the guideline. However, measuring serum protein S100B in patients not recommended by the guideline rendered unacceptably low sensitivity with possible missed TICHs as a consequence. To further delineate the magnitude and impact of non-adherence, more studies are needed.


Brain Concussion , Craniocerebral Trauma , Humans , Guideline Adherence , Prospective Studies , Craniocerebral Trauma/diagnosis , Craniocerebral Trauma/therapy , Biomarkers , S100 Calcium Binding Protein beta Subunit
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