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J Food Prot ; 71(10): 2115-8, 2008 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-18939763

RESUMEN

In Brazil, the incidence of Bacillus cereus outbreaks is unknown, and there is little information about B. cereus occurrence in food. In addition, data on toxin production and genetic characterization of the B. cereus isolates cannot be found. This pathogen causes two distinct types of toxin-mediated foodborne illnesses known as diarrheal and emetic syndromes. Diarrheal syndrome has been linked to three different enterotoxins: two protein complexes, hemolysin BL (HBL) and nonhemolytic enterotoxin (NHE); and an enterotoxic protein, cytotoxin K (cytK). Emetic syndrome is related to cereulide, a toxin encoded by the ces gene. In this study, NHE and HBL production capacities of 155 strains of B. cereus isolated from Brazilian food products were evaluated with an immunoassay. Strains were also tested for the presence of the genes of the HBL and NHE complexes, cytK, cytK-1, cytK-2, and ces, using PCR. HBL was detected in 105 (67.7%) strains and NHE in 154 (99.4%) strains. All the strains harbored at least one gene of the NHE complex, while 96.1% of them were positive for at least one of those of the HBL complex. Genes cytK1 and ces were not detected. All strains showed toxigenic capacity and could represent a risk for consumers if good practices are not followed. This is the first report on toxigenic and genetic profiles of B. cereus strains isolated in Brazil.


Asunto(s)
Bacillus cereus/genética , Bacillus cereus/metabolismo , Enterotoxinas/biosíntesis , Enterotoxinas/genética , Contaminación de Alimentos/análisis , Secuencia de Bases , Seguridad de Productos para el Consumidor , ADN Bacteriano/química , ADN Bacteriano/genética , Depsipéptidos/metabolismo , Eméticos/metabolismo , Microbiología de Alimentos , Amplificación de Genes , Proteínas Hemolisinas/metabolismo , Humanos , Reacción en Cadena de la Polimerasa/métodos
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