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1.
Arq Neuropsiquiatr ; 71(1): 40-5, 2013 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-23288021

RESUMEN

UNLABELLED: Spinal cord tumors are a rare neoplasm of the central nervous system (CNS). The occurrence of metastases is related to poor prognosis. The authors analyzed one series of metastasis cases and their associated mortality. METHODS: Clinical characteristics were studied in six patients with intramedullary tumors with metastases in a series of 71 surgical cases. RESULTS: Five patients had ependymomas of which two were WHO grade III. The patient with astrocytoma had a grade II histopathological classification. Two patients required shunts for hydrocephalus. The survival curve showed a higher mortality than the general group of patients with no metastases in the CNS (p<0.0001). CONCLUSION: Mortality is elevated in patients with metastasis and greater than in patients with only primary lesions. The ependymomas, regardless of their degree of anaplasia, are more likely to cause metastasis than spinal cord astrocytomas.


Asunto(s)
Astrocitoma , Neoplasias Encefálicas , Ependimoma , Neoplasias Meníngeas , Neoplasias de la Médula Espinal , Adulto , Astrocitoma/mortalidad , Astrocitoma/secundario , Neoplasias Encefálicas/mortalidad , Neoplasias Encefálicas/secundario , Ependimoma/mortalidad , Ependimoma/secundario , Femenino , Humanos , Imagen por Resonancia Magnética , Masculino , Neoplasias Meníngeas/mortalidad , Neoplasias Meníngeas/secundario , Persona de Mediana Edad , Estadificación de Neoplasias , Pronóstico , Neoplasias de la Médula Espinal/mortalidad , Neoplasias de la Médula Espinal/patología , Tasa de Supervivencia
2.
Arq. neuropsiquiatr ; Arq. neuropsiquiatr;71(1): 40-45, Jan. 2013. ilus, tab
Artículo en Inglés | LILACS | ID: lil-662408

RESUMEN

Spinal cord tumors are a rare neoplasm of the central nervous system (CNS). The occurrence of metastases is related to poor prognosis. The authors analyzed one series of metastasis cases and their associated mortality. METHODS: Clinical characteristics were studied in six patients with intramedullary tumors with metastases in a series of 71 surgical cases. RESULTS: Five patients had ependymomas of which two were WHO grade III. The patient with astrocytoma had a grade II histopathological classification. Two patients required shunts for hydrocephalus. The survival curve showed a higher mortality than the general group of patients with no metastases in the CNS (p<0.0001). CONCLUSION: Mortality is elevated in patients with metastasis and greater than in patients with only primary lesions. The ependymomas, regardless of their degree of anaplasia, are more likely to cause metastasis than spinal cord astrocytomas.


Tumores da medula espinhal são neoplasias raras do sistema nervoso central (SNC). A ocorrência de metástases é relacionada a pior prognóstico. Os autores analisaram uma série de casos de metástases e a mortalidade relacionada. MÉTODO: Foram estudadas as características clínicas em seis pacientes com metástases tumorais numa série de 71 casos operados. RESULTADOS: Cinco pacientes tinham ependimomas e dois dos quais foram grau III pela classificação da OMS. O paciente portador de astrocitoma tinha classificação histopatológica de grau II. Dois pacientes necessitaram de derivação devido à hidrocefalia. A curva de sobrevivência mostrou mortalidade mais elevada no grupo de pacientes com disseminação pelo SNC (p<0,0001). CONCLUSÃO: A mortalidade, além de elevada em pacientes com metástases, é maior do que em pacientes apenas com lesão primária. Os ependimomas, independentemente do seu grau de anaplasia, costumam causar mais metástases do que os astrocitomas medulares.


Asunto(s)
Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Astrocitoma , Neoplasias Encefálicas , Ependimoma , Neoplasias Meníngeas , Neoplasias de la Médula Espinal , Astrocitoma/mortalidad , Astrocitoma/secundario , Neoplasias Encefálicas/mortalidad , Neoplasias Encefálicas/secundario , Ependimoma/mortalidad , Ependimoma/secundario , Imagen por Resonancia Magnética , Neoplasias Meníngeas/mortalidad , Neoplasias Meníngeas/secundario , Estadificación de Neoplasias , Pronóstico , Tasa de Supervivencia , Neoplasias de la Médula Espinal/mortalidad , Neoplasias de la Médula Espinal/patología
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