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1.
Mol Brain ; 14(1): 146, 2021 09 20.
Article En | MEDLINE | ID: mdl-34544461

Chronic postsurgical pain (CPSP) is a serious problem. We developed a mouse model of CPSP induced by electrocautery and examined the mechanism of CPSP. In this mouse model, while both incision and electrocautery each produced acute allodynia, persistent allodynia was only observed after electrocautery. Under these conditions, we found that the mRNA levels of Small proline rich protein 1A (Sprr1a) and Annexin A10 (Anxa10), which are the key modulators of neuropathic pain, in the spinal cord were more potently and persistently increased by electrocautery than by incision. Furthermore, these genes were overexpressed almost exclusively in chronic postsurgical pain-activated neurons. This event was associated with decreased levels of tri-methylated histone H3 at Lys27 and increased levels of acetylated histone H3 at Lys27 at their promoter regions. On the other hand, persistent allodynia and overexpression of Sprr1a and Anxa10 after electrocautery were dramatically suppressed by systemic administration of GSK-J4, which is a selective H3K27 demethylase inhibitor. These results suggest that the effects of electrocautery contribute to CPSP along with synaptic plasticity and epigenetic modification.


Annexins/biosynthesis , Cornified Envelope Proline-Rich Proteins/biosynthesis , Electrocoagulation/adverse effects , Histone Code , Hyperalgesia/etiology , Nerve Tissue Proteins/biosynthesis , Neuralgia/genetics , Neurons/physiology , Pain, Postoperative/genetics , Spinal Cord/physiopathology , Animals , Annexins/genetics , Benzazepines/pharmacology , Benzazepines/therapeutic use , Cornified Envelope Proline-Rich Proteins/genetics , Disease Models, Animal , Female , Foot Injuries/physiopathology , Gene Expression Regulation , Gene Knock-In Techniques , Genes, Reporter , Genes, fos , Histones/metabolism , Hyperalgesia/drug therapy , Hyperalgesia/physiopathology , Jumonji Domain-Containing Histone Demethylases/antagonists & inhibitors , Lysine/metabolism , Male , Methylation , Mice , Mice, Inbred C57BL , Nerve Tissue Proteins/genetics , Neuralgia/drug therapy , Neuralgia/physiopathology , Neurons/drug effects , Pain, Postoperative/drug therapy , Pain, Postoperative/physiopathology , Pyrimidines/pharmacology , Pyrimidines/therapeutic use , RNA, Messenger/biosynthesis , RNA, Messenger/genetics , Tamoxifen/analogs & derivatives , Tamoxifen/pharmacology
2.
Med Sci Monit ; 27: e931969, 2021 Aug 29.
Article En | MEDLINE | ID: mdl-34455415

BACKGROUND Midfoot deformity and injury can affect the internal pressure distribution of the foot. This study aimed to use 3D finite element and biomechanical analyses of midfoot von Mises stress levels in flatfoot, clubfoot, and Lisfranc joint injury. MATERIAL AND METHODS Normal feet, flatfeet, clubfeet (30 individuals each), and Lisfranc injuries (50 individuals) were reconstructed by CT, and 3D finite element models were established by ABAQUS. Spring element was used to simulate the plantar fascia and ligaments and set hyperelastic coefficients in encapsulated bone and ligaments. The stance phase was simulated by applying 350 N on the top of the talus. The von Mises stress of the feet and ankle was visualized and analyzed. RESULTS The von Mises stress on healthy feet was higher in the lateral metatarsal and ankle bones than in the medial metatarsal bone. Among the flatfoot group, the stress on the metatarsals, talus, and navicular bones was significantly increased compared with that on healthy feet. Among patients with clubfeet, stress was mainly concentrated on the talus, and stress on the lateral metatarsal and navicular bones was significantly lower. The von Mises stress on the fractured bone was decreased, and the stress on the bone adjacent to the fractured bone was higher in Lisfranc injury. During bone dislocation alone or fracture accompanied by dislocation, the von Mises stress of the dislocated bone tended to be constant or increased. CONCLUSIONS Prediction of von Mises stress distribution may be used clinically to evaluate the effects of deformity and injury on changes in structure and internal pressure distribution on the midfoot.


Clubfoot/physiopathology , Finite Element Analysis/statistics & numerical data , Flatfoot/physiopathology , Foot Injuries/physiopathology , Foot Joints/physiopathology , Joint Diseases/physiopathology , Stress, Mechanical , Adult , Biomechanical Phenomena , Female , Follow-Up Studies , Foot Joints/injuries , Humans , Male , Prognosis
3.
Acta Orthop Traumatol Turc ; 55(3): 258-264, 2021 May.
Article En | MEDLINE | ID: mdl-34100368

OBJECTIVE: The aim of this study was to compare clinical and radiological outcomes of screw fixation alone versus screw with small locking plate fixation techniques in the management of intra-articular calcaneal fractures by minimal invasive surgery. METHODS: A total of 42 patients treated with minimally invasive surgery because of an intra-articular calcaneal fracture were retrospectively reviewed and included in the study. The patient were then divided into two groups based on the implemented surgical technique: Group A, 20 patients (16 male, 4 female; mean age = 43.41 ± 15.50) receiving screw fixation alone and group B, 22 patients (17 male, 5 female; mean age = 43.38 ± 14.00) receiving screw with small locking plate fixation. The radiographic assessment included Bohler's, Gissane, joint line parallel, and calcaneal varus angles at immediate post-operative and 2-year follow up period through the calcaneal axial and lateral foot radiographs. RESULTS: There was a significant increase in joint line parallel angle from post-operative period to 2-year follow up in Group A compared to Group B, mean (SD) 3.27 (2.15) degrees versus (vs) 0.44 (3.00) degrees, P = 0.025. No statistical significant difference of the immediate, 2-year post-operative period and the change in Bohler's-Gissane angle, calcaneal varus, and FAAM of ADL between groups were observed, P > 0.05. For time-point comparisons in each group, there was a significant loss of calcaneal varus and increase in joint line parallel angle from post-operative period to 2-year follow up in Group A, from mean (SD) 1.82 (11.22) to 4.41 (9.73) degrees and 4.09 (5.32) to 7.36 (5.24) degrees, P = 0.047 and <0.0001, respectively. Group A had statistical significant less complications as zero vs 5, P = 0.049. CONCLUSION: The screw fixation alone seems to provide inferior stability of posterior facet fixation and calcaneal varus reduction with lower complication rates compared to screw with small-locking plate fixation. LEVEL OF EVIDENCE: Level III, Therapeutic Study.


Calcaneus , Foot Injuries , Fracture Fixation, Internal , Intra-Articular Fractures , Postoperative Complications , Adult , Bone Plates , Bone Screws , Calcaneus/diagnostic imaging , Calcaneus/injuries , Calcaneus/surgery , Female , Foot Injuries/diagnostic imaging , Foot Injuries/physiopathology , Foot Injuries/surgery , Fracture Fixation, Internal/adverse effects , Fracture Fixation, Internal/instrumentation , Fracture Fixation, Internal/methods , Humans , Intra-Articular Fractures/diagnostic imaging , Intra-Articular Fractures/surgery , Male , Minimally Invasive Surgical Procedures/adverse effects , Minimally Invasive Surgical Procedures/methods , Outcome and Process Assessment, Health Care , Postoperative Complications/diagnosis , Postoperative Complications/etiology , Radiography/methods , Retrospective Studies
4.
Clin Orthop Relat Res ; 479(6): 1265-1272, 2021 06 01.
Article En | MEDLINE | ID: mdl-33428344

BACKGROUND: Most intraarticular displaced calcaneal fractures are accompanied by bone defects after surgical treatment, but the concern about negative effects of bone defects has not been resolved yet owing to the few studies on this issue. Therefore, studies on volumetric changes in bone defects over time and the correlation between postoperative outcomes and residual bone defects will be helpful to address the controversy on the necessity of bone grafting in bone defects of calcaneal fractures. QUESTIONS/PURPOSES: (1) Do bone defects change in size in the first year after surgical treatment of displaced intraarticular calcaneal fractures? (2) Does the size of residual bone defects correlate with postoperative radiographic or clinical outcomes? METHODS: Between 2015 and 2019, 99 patients with displaced intraarticular calcaneal fractures visited the investigators' institution, of whom 95 received surgical treatment. Of the patients treated with surgery, 25% (24 of 95) did not undergo open reduction and internal fixation via an extensile lateral approach, and 19% (18 of 95) had multiple fractures, bilateral fractures, open fractures, or a history of previous surgery on the calcaneus; all of these patients were excluded. During the study period, CT was routinely performed for calcaneal fractures immediately after and 12 months after the surgery, but 6% (6 of 95) of the patients had insufficient CT data due to loss to follow-up before 12 months or other reasons, leaving 47 patients for evaluation in this retrospective study. Fractures were fixed with plate and screws, and bone grafting was not performed in all patients. To answer our first question, which was on the changes in bone defects over time, volumetric measurements of the bone defect were performed using CT via the ITK-SNAP software. The percentage of volumetric change was calculated as a fraction of the volumetric change over 12 months from the initial volume. The percentage of the residual bone defect was calculated as a fraction of the volume of the residual bone defect relative to the volume of the entire calcaneus. To answer our second question, which was on the correlation between residual bone defects and postoperative outcomes, we assessed the Böhler angle, Gissane angle, calcaneal height, Olerud-Molander Ankle Score (OMAS), and VAS score for pain and compared these parameters with the size of the residual bone defect using the Pearson correlation coefficient. The OMAS and VAS scores for pain were evaluated and recorded during patient visits, and we obtained the scores through a chart review. All volumetric measurements and radiographic evaluations were performed by two orthopaedic surgeons, and the intraobserver and interobserver reliability were assessed using the intraclass correlation coefficient. RESULTS: The mean volume of the bone defect measured using CT was 4 ± 3 cm3 immediately after surgery and 1 ± 1 cm3 12 months after surgery. During the first 12 months after surgery, the mean volume of the bone defect was reduced by 77% (95% confidence interval 73% to 80%). The mean residual bone defect in the entire calcaneus was 2% (95% CI 1% to 2%), and none of the postoperative outcomes were correlated with the residual bone defect. CONCLUSION: As bone defects substantially resolve without treatment, surgeons do not need to use bone graft for the surgical treatment of displaced intraarticular calcaneal fractures. Future studies that include patients who underwent bone grafting for the treatment of calcaneal fractures are needed to confirm our findings and to further investigate whether bone grafting has additional benefits for the recovery of bone defects. LEVEL OF EVIDENCE: Level III, therapeutic study.


Calcaneus/injuries , Foot Injuries/surgery , Fracture Healing/physiology , Intra-Articular Fractures/surgery , Postoperative Complications/physiopathology , Adult , Calcaneus/physiopathology , Female , Foot Injuries/physiopathology , Fracture Fixation, Internal/methods , Humans , Intra-Articular Fractures/physiopathology , Male , Middle Aged , Postoperative Complications/etiology , Postoperative Period , Remission, Spontaneous , Retrospective Studies , Treatment Outcome
5.
Med Sci Sports Exerc ; 53(1): 102-107, 2021 01.
Article En | MEDLINE | ID: mdl-32769811

PURPOSE: Despite the health benefits of running, the prevalence of running-related injuries (RRI) remains high. The underlying risk factors between these injuries are still not well understood. Therefore, the aim of this study was to compare biomechanical, anthropometric, and demographic injury risk factors between different locations in injured recreational runners. METHODS: In this retrospective case-control analysis, 550 injured runners (49.6% female) with a medically diagnosed RRI were included. All runners had undergone an instrumented treadmill analysis to determine habitual footstrike pattern, vertical instantaneous load rate, peak vertical ground reaction force (vGRF) and cadence. Injuries were classified by location according to a recent consensus statement. A logistic regression model was used to determine the association between the biomechanical parameters and RRI locations. Because injuries can be associated with age, sex, and body mass index, these variables were also entered into the logistic regression. RESULTS: Strike pattern and peak vGRF were the only biomechanical variable distinguishing an injury from the group of injuries. A midfoot strike differentiated Achilles tendon injuries (odds ratio [OR], 2.27; 90% confidence interval [CI], 1.17-4.41) and a forefoot strike distinguished posterior lower leg injuries (OR, 2.59; 90% CI, 1.50-4.47) from the rest of the injured group. Peak vGRF was weakly associated with hip injuries (OR, 1.14; 90% CI, 1.05-1.24). Female sex was associated with injuries to the lower leg (OR, 2.65; 90% CI, 1.45-4.87) and hip/groin (OR, 2.22; 90% CI, 1.43-3.45). Male sex was associated with Achilles tendon injuries (OR, 1.923; 90% CI, 1.094-3.378). CONCLUSIONS: Sex, foot strike pattern, and vGRF were the only factors that distinguished specific injury locations from the remaining injury locations.


Lower Extremity/injuries , Lower Extremity/physiopathology , Running/injuries , Achilles Tendon/injuries , Achilles Tendon/physiopathology , Adult , Age Factors , Biomechanical Phenomena , Body Mass Index , Case-Control Studies , Female , Foot/physiology , Foot Injuries/etiology , Foot Injuries/physiopathology , Gait , Groin/injuries , Groin/physiopathology , Hip Injuries/etiology , Hip Injuries/physiopathology , Humans , Knee Injuries/etiology , Knee Injuries/physiopathology , Logistic Models , Male , Middle Aged , Retrospective Studies , Risk Factors , Sex Factors , Young Adult
6.
Foot Ankle Spec ; 14(2): 105-113, 2021 Apr.
Article En | MEDLINE | ID: mdl-31920101

Purpose. It is currently still common practice to obtain conventional radiographs in the follow-up of surgically treated displaced intra-articular calcaneal fractures at regular intervals. There is, however, insufficient evidence that these radiographs can be used to predict functional outcome. The aim of the current study was to evaluate the correlation between the most commonly used angles on lateral radiographs and disease-specific patient-reported outcome measures (PROMs). Methods. Two available databases, containing a total of 233 patients, were used in this study. Eleven angles on the lateral images of the preoperative and at 1-year follow-up radiographs were measured. The 6 most commonly used angles were also measured immediately postoperatively. These 6 most commonly used angles were correlated with PROMs (American Orthopaedic Foot and Ankle Society hindfoot score, Foot Function Index) by a Spearman's rho analysis. After a Bonferroni correction was applied, a P value of <.0042 was considered to be statistically significant. Results. After exclusion of bilateral fractures, primary arthrodesis, open fractures, wound infections, other wound complications, nonavailable radiographs, and nonresponders, 86 patients remained. No significant correlations were found between the measured angles on the preoperative and at 1-year follow-up radiographs and the PROMs. Conclusion. No apparent correlation between lateral radiograph morphology and outcome was detected. Therefore, long-term follow-up radiographs after confirmed healing may be restricted to patients with persistent complaints on indication.Levels of Evidence: Prognostic, Level IV: Retrospective.


Calcaneus/diagnostic imaging , Calcaneus/surgery , Foot Injuries/diagnostic imaging , Foot Injuries/surgery , Fracture Fixation, Internal/methods , Intra-Articular Fractures/diagnostic imaging , Intra-Articular Fractures/surgery , Adult , Calcaneus/injuries , Calcaneus/physiopathology , Female , Follow-Up Studies , Foot Injuries/physiopathology , Humans , Intra-Articular Fractures/physiopathology , Male , Middle Aged , Patient Reported Outcome Measures , Range of Motion, Articular
7.
Burns ; 47(3): 587-593, 2021 05.
Article En | MEDLINE | ID: mdl-32888746

BACKGROUND: Both diabetes mellitus (DM) and burn injuries lead to physical and psychological impairments. Foot burns are still a challenging health condition because of its important sensory role. No previous studies have assessed the physical therapy intervention on diabetic patients with foot burns. Therefore, this study aimed to assess the potential efficacy of sensorimotor exercise on pain, proprioception, mobility, balance, and quality of life in diabetic patients with foot burns. METHODS: Between July 2019 and February 2020, thirty-three diabetic patients with foot burns, aged 32 to 46yrs, were enrolled in this randomized control study, and randomized consecutively into two groups, study group (n=16) and control group (n=17). The study group underwent a sensorimotor exercise program thrice a week for 12 consecutive weeks, however the control group did not undergo the exercise intervention. Both groups were instructed to conduct home exercises. Visual analogue scale (VAS), proprioceptive responses, time-up and go (TUG) values, and short form-36 (SF-36) have been assessed prior and subsequent to the study intervention. RESULTS: No significant differences were observed between groups regarding baseline data (p˃0.05). Subsequent to 12wk intervention, the study group showed significant improvements in outcome measures (proprioceptive responses, p˂0.05, VAS, p˂0.001, TUG, p=0.003, and SF-36, p˂0.001) and the control group exhibited significant changes in VAS and SF-36 (p=0.004, p=0.043 respectively) however, no significant changes were found in proprioceptive responses and TUG values (p˃0.05). Between groups, the post-intervention comparison demonstrated statistical differences with tending toward the study group (proprioceptive responses, p˂0.05, VAS, p˂0.001, TUG, p=0.013, and SF-36, p=0.046). CONCLUSIONS: Sensorimotor exercise training may improve, pain, proprioceptive responses, mobility, balance, and quality of life in diabetic patients with foot burns. Physiotherapists and rehabilitation providers should include the sensorimotor exercise in their protocols in the treatment of diabetic patients with foot burns.


Burns/complications , Exercise Therapy/standards , Foot Injuries/complications , Sensorimotor Cortex/injuries , Adult , Burns/physiopathology , Diabetes Mellitus/metabolism , Diabetes Mellitus/physiopathology , Early Ambulation/methods , Exercise Therapy/methods , Exercise Therapy/statistics & numerical data , Female , Foot/physiopathology , Foot Injuries/physiopathology , Humans , Male , Middle Aged , Pain Management/standards , Pain Management/statistics & numerical data , Pain Measurement , Proprioception/physiology , Quality of Life/psychology , Sensorimotor Cortex/physiopathology , Single-Blind Method , Treatment Outcome
8.
Gait Posture ; 83: 147-151, 2021 01.
Article En | MEDLINE | ID: mdl-33152609

BACKGROUND: The purpose of this study was to analyse the effects of ten weeks of different running-retraining programmes on rearfoot strike (RFS) prevalence in adolescents. RESEARCH QUESTION: it is possible to change foot strike pattern in adolescents? METHODS: A total of 180 children (45.3% girls), aged 13-16 years, participated in this intervention study. The children were randomly assigned to one of three experimental groups (EGs) that each carried out a different retraining programme, based on running technique (n = 39), a 15% increased step frequency (SF) (n = 37) and barefoot training (n = 30), performed for three days each week. A control group (CG) (n = 43) did not perform any retraining. A 2D video-based analysis (240 Hz) was used to determine the RFS. RESULTS: At baseline, no significant differences in RFS prevalence were found between the EGs and the CG in either the left (χ2 = 2.048; p = 0.559) or the right foot (χ2 = 0.898; p = 0.825). In the post-test, no significant differences were found for the left foot (χ2 = 7.102; p = 0.069), but there were significant differences for the right foot (χ2 = 9.239; p = 0.025) were observed. In the re-test, no significant differences were found for either the left foot (χ2 = 2.665; p = 0.273) or the right foot (χ2 = 2.182; p = 0.325). In addition, no group displayed significant changes in RFS prevalence from the pre-test to the re-test. There was a trend towards a reduction in the RFS prevalence in both the increased SF group and the barefoot group. MEANING: The main finding of this study was that certain running-retraining programmes performed three times per week for ten weeks are not enough to modify the adolescent foot strike pattern (FSP).


Biomechanical Phenomena/physiology , Foot Injuries/etiology , Foot/physiopathology , Running/physiology , Adolescent , Female , Foot Injuries/physiopathology , Humans , Longitudinal Studies , Male , Time Factors
9.
Acta Orthop Traumatol Turc ; 54(5): 488-496, 2020 Sep.
Article En | MEDLINE | ID: mdl-33155557

OBJECTIVE: The aim of this study was to assess the early operative results of a staged progressive reduction technique using a bilateral external fixator in the treatment of patients with open Lisfranc fracture dislocations. METHODS: In this retrospective study, 21 patients (5 women and 16 men; mean age=44.4 years; age range=24 to 69 years) with open Lisfranc fracture dislocations were included. All the patients were treated in a staged manner from 2012 to 2015. The mean follow-up was 15.4 months (range=12 to 24 months). A two-stage surgical protocol was performed for each patient. At the first stage, a bilateral spanning external fixator was applied across the injured Lisfranc joint, and the length of the disrupted columns was restored by distraction process. Vacuum-assisted closure was used if required. At the second stage, the external fixator was removed, and open reduction and internal fixation were carried out. The time interval between the first and second stages and postoperative complications were documented. To assess the functional status of the patients, the visual analog scale (VAS) and the American Orthopaedic Foot - Ankle Society (AOFAS) midfoot scale were measured at the final follow-up. Radiographic parameters indicating the alignment of the midfoot after the second operation were examined. RESULTS: Deep infection in one patient and superficial infection in 2 patients were observed. Venous thrombosis was detected in 3 patients. The mean interval between the first and second stages was 18.6 days (range=8 to 48 days). The first metatarso-cuneiform step-off (p=0.002) and the second metatarso-cuneiform step-off (p=0.000) significantly improved at the final follow-up. The mean VAS score was 2.4 (range=0-5), and the mean AOFAS score was 76.3 (range=63 to 97). Primary arthrodesis was performed in seven patients, and six of the remaining 14 patients developed post-traumatic arthritis. CONCLUSION: With a low risk of complications, the staged progressive reduction protocol using an adjustable bilateral external fixator can be an effective treatment to achieve and maintain anatomic reduction for patients with open Lisfranc fracture dislocations in a short-time follow-up. LEVEL OF EVIDENCE: Level IV, Therapeutic study.


External Fixators , Foot Bones , Foot Injuries , Fracture Dislocation/surgery , Fracture Fixation, Internal , Fractures, Open/surgery , Adult , Arthrodesis/methods , Female , Foot Bones/diagnostic imaging , Foot Bones/injuries , Foot Bones/surgery , Foot Injuries/diagnostic imaging , Foot Injuries/physiopathology , Foot Injuries/surgery , Fracture Fixation, Internal/adverse effects , Fracture Fixation, Internal/instrumentation , Fracture Fixation, Internal/methods , Humans , Male , Pain Measurement/methods , Postoperative Complications/etiology , Retrospective Studies , Treatment Outcome , Wound Infection/etiology , Wound Infection/prevention & control
10.
Clin Sports Med ; 39(4): 801-818, 2020 Oct.
Article En | MEDLINE | ID: mdl-32892968

Turf toe injuries should be recognized and treated early to prevent long-term disability. The accurate clinical assessment and radiological evaluation of appropriate cases is important. Both conservative and surgical treatments play a major role in getting athletes back to their preinjury level. There are more recent reported case series and systemic reviews that encourage operative treatment as early as possible for grade III turf toe injury. If the patient presents late from a traumatic hallux injury with subsequent degenerative changes or has hallux rigidus from other etiologies, a first metatarsophalangeal arthrodesis should be considered to minimize pain and improve function.


Arthrodesis , Athletic Injuries/surgery , Foot Injuries/surgery , Hallux Rigidus/surgery , Hallux Valgus/surgery , Hallux/injuries , Metatarsophalangeal Joint/injuries , Arthritis/etiology , Arthritis/physiopathology , Arthritis/surgery , Athletic Injuries/physiopathology , Foot Injuries/etiology , Foot Injuries/physiopathology , Hallux/physiopathology , Hallux/surgery , Hallux Rigidus/etiology , Hallux Rigidus/physiopathology , Hallux Valgus/etiology , Hallux Valgus/physiopathology , Humans , Joint Instability/etiology , Joint Instability/physiopathology , Joint Instability/surgery , Metatarsophalangeal Joint/surgery , Treatment Outcome
11.
Clin Sports Med ; 39(4): 859-876, 2020 Oct.
Article En | MEDLINE | ID: mdl-32892972

Painful accessory navicular and spring ligament injuries in athletes are different entities from more common posterior tibialis tendon problems seen in older individuals. These injuries typically affect running and jumping athletes, causing medial arch pain and in severe cases a pes planus deformity. Diagnosis requires a detailed physical examination, standing radiographs, and MRI. Initial treatment focuses on rest, immobilization, and restriction from sports. Orthotic insoles may alleviate minor pain, but many patients need surgery to expedite recovery and return to sports. The authors review their approach to these injuries and provide surgical tips along with expected rehabilitation to provide optimal outcomes.


Athletic Injuries/therapy , Foot Injuries/therapy , Ligaments, Articular/injuries , Musculoskeletal Pain/etiology , Orthopedic Procedures/methods , Tarsal Bones/abnormalities , Athletic Injuries/diagnosis , Athletic Injuries/etiology , Athletic Injuries/physiopathology , Flatfoot/etiology , Flatfoot/therapy , Foot Diseases/diagnosis , Foot Diseases/physiopathology , Foot Diseases/therapy , Foot Injuries/diagnosis , Foot Injuries/etiology , Foot Injuries/physiopathology , Humans , Ligaments, Articular/surgery , Musculoskeletal Pain/therapy , Tarsal Bones/injuries , Tarsal Bones/physiopathology , Treatment Outcome
12.
Surg Clin North Am ; 100(4): 707-725, 2020 Aug.
Article En | MEDLINE | ID: mdl-32681871

Chronic wounds often are the result of bone deformities, compounded by musculotendinous and ligamentous imbalance. Sensory neuropathy places patients at greater risk for acute wounds to develop into chronic wounds. Etiologies of these deforming forces include Charcot neuroarthropathy, trauma, and congenital and acquired neuromuscular disorders. Management of these deformities ranges from simple relief of pressure with soft inserts to bracing for mechanical instability. Correction of more complex deformities requires resection of bone, osteotomies, fusions, and external fixation. Tendon and ligament imbalance must be addressed at all levels of deformity. Postoperatively, patients must be re-evaluated for continuation of orthoses and bracing.


Ankle Joint/surgery , Foot/surgery , Wound Healing/physiology , Wounds and Injuries/surgery , Ankle Injuries/physiopathology , Ankle Injuries/surgery , Braces , Chronic Disease , Debridement , Equipment Design , Foot Injuries/physiopathology , Foot Injuries/surgery , Humans , Orthotic Devices , Osteomyelitis/physiopathology , Osteomyelitis/surgery , Soft Tissue Injuries/surgery , Surgical Flaps , Tendinopathy/physiopathology , Tendinopathy/surgery , Wounds and Injuries/physiopathology
13.
J Sports Sci ; 38(16): 1836-1843, 2020 Aug.
Article En | MEDLINE | ID: mdl-32362240

Chronic foot and ankle injuries are common in dancers; understanding how lower extremity loading changes in response to altered task goals can be beneficial for rehabilitation and injury prevention strategies. The purpose of this study was to examine mechanical demands during jump take-offs when the task goal was modified to focus on either increasing jump distance or increasing jump height. It was hypothesized that a jump strategy focused on height would result in decreased energetic demands on the foot and ankle joints. Thirty healthy, experienced female dancers performed saut de chat leaps while travelling as far as possible (FAR) or jumping as high as possible (UP). Ground reaction force (GRF) impulses and peak sagittal plane net joint moments and sagittal plane mechanical energy expenditure (MEE) of the metatarsophalangeal (MTP), ankle, knee, and hip joints were calculated. During take-off, vertical and horizontal braking GRF impulses were greater and horizontal propulsive GRF impulse was lower in the UP condition. MEE at the MTP, ankle, and hip joints was lower in UP, and MEE at the knee was higher in UP. These results suggest that a strategy focused on height may be helpful in unloading the ankle and MTP joints during dance leaps.


Dancing/physiology , Lower Extremity/physiology , Adolescent , Adult , Ankle Injuries/physiopathology , Ankle Joint/physiology , Biomechanical Phenomena , Dancing/injuries , Energy Metabolism , Female , Foot Injuries/physiopathology , Hip Joint/physiology , Humans , Knee Joint/physiology , Metatarsophalangeal Joint/physiology , Time and Motion Studies , Young Adult
14.
J Sport Rehabil ; 29(7): 1038-1041, 2020 Sep 01.
Article En | MEDLINE | ID: mdl-32357314

BACKGROUND: Region-specific patient-reported outcomes (PROs) are commonly used in rehabilitation medicine. Digital versions of PROs may be implemented into electronic medical records and are also commonly used in research, but the validity of this method of administration (MOA) must be established. PURPOSE: To determine the agreement between and compare the test-retest reliability of a paper version (FAAM-P) and digital version (FAAM-D) of the Foot and Ankle Ability Measure (FAAM). STUDY DESIGN: Randomized, nonblinded, crossover observational study. METHODS: A total of 90 adults were randomized to complete the FAAM-P or FAAM-D first, and then completed the second MOA (first day [D1]). The FAAM-D was a digital adaptation of both FAAM-P subscales on Qualtrics. Identical test procedures were completed 1 week later (D2). Data were removed if a participant scored 100% on both MOA, reported injury between D1 and D2, or did not complete both MOA. Agreement was assessed on 46 participants between the 2 MOA using intraclass correlation coefficients (ICC) at D1. There was good-to-excellent test-retest reliability for the FAAM activities of daily living. RESULTS: The authors observed good agreement between the FAAM-P and FAAM-D for the activities of daily living (ICC = .88) and sport scales (ICC = .87). Test-retest reliability was good-to-excellent for the FAAM activities of daily living (FAAM-P: ICC = .87; FAAM-D: ICC = .89) and sport (FAAM-P: ICC = .71; FAAM-D: ICC = .91). CONCLUSIONS: The MOA does not appear to affect the responses on the FAAM; however, the authors observed slightly higher reliability on the FAAM-D. The FAAM-D is sufficient to be used for generating practice-based evidence in rehabilitation medicine.


Ankle Injuries/physiopathology , Ankle Injuries/rehabilitation , Disability Evaluation , Foot Injuries/physiopathology , Foot Injuries/rehabilitation , Patient Reported Outcome Measures , Surveys and Questionnaires/standards , Activities of Daily Living , Adult , Aged , Cross-Over Studies , Female , Humans , Male , Middle Aged , Reproducibility of Results , Sports , Young Adult
15.
Orthop Nurs ; 39(2): 114-118, 2020.
Article En | MEDLINE | ID: mdl-32218007

Foot surgery is common. Orthopaedic nurses charged with evaluating and treating patients who have undergone foot surgery are required to evaluate the vascular status of the patient's foot (or feet). As a result, these nurses are often the first to identify vascular issues. This article provides orthopaedic nurses with the background to understand how the patient's history, the procedure(s) performed, and a thorough assessment of the foot's circulation will allow them to promptly identify circulatory problems and potentially save a patient from having a serious complication.


Foot Injuries/blood , Orthopedic Procedures/adverse effects , Orthopedic Procedures/methods , Foot/blood supply , Foot/physiopathology , Foot Injuries/physiopathology , Humans , Vascular Diseases/diagnosis , Vascular Diseases/physiopathology , Vascular Diseases/prevention & control
17.
Phys Ther Sport ; 42: 107-115, 2020 Mar.
Article En | MEDLINE | ID: mdl-31962191

OBJECTIVES: To investigate the effects of a foot training program on muscle morphology and strength as well as running biomechanics in healthy recreational runners. DESIGN: Proof-of-concept, single-blind randomized controlled trial. SETTINGS: Runners were allocated to a control (CG) or an intervention (IG) group. The intervention focused on strengthening the intrinsic foot muscles and their activation during weight-bearing activities. All participants were assessed at baseline and after 8-weeks. PARTICIPANTS: Twenty-eight healthy recreational long-distance runners not habituated to minimalist running shoes or barefoot running. MAIN OUTCOMES MEASURES: Outcomes were hallux and toes strength; foot function, cross-sectional area and volume of the abductor hallucis (ABH), abductor digiti minimi (ABV), flexor digitorum brevis (FDB), and flexor hallucis brevis; medial longitudinal arch range of motion and stiffness; vertical and antero-posterior propulsive impulses during running. RESULTS: Compared to the CG, an increase was found in the IG for the volume of all muscles investigated and for vertical propulsive impulse during running. Correlations were found between vertical propulsive impulse and volume of ABH(r = 0.40), ABV(r = 0.41), and FDB(r = 0.69). CONCLUSION: The foot exercise protocol effectively increased intrinsic foot muscle volume and propulsive forces in recreational runners. This shows that intrinsic muscle strengthening affects running mechanics and suggests that it may improve running performance.


Exercise Therapy/methods , Foot Injuries/rehabilitation , Foot/physiopathology , Muscle, Skeletal/physiopathology , Running/physiology , Weight-Bearing/physiology , Adolescent , Adult , Biomechanical Phenomena , Female , Foot Injuries/physiopathology , Humans , Male , Middle Aged , Single-Blind Method , Young Adult
18.
Foot Ankle Surg ; 26(1): 47-53, 2020 Jan.
Article En | MEDLINE | ID: mdl-30509556

BACKGROUND: Although the classic definition of the Turf-toe injury refers to a very specific clinical and pathological picture, we think that the concept can be broadened to encompass a wide variety of traumatic lesions of the first metatarsophalangeal joint (MTP1). These are lesions typically difficult to diagnose, with a large variation of outcomes and a potential to impair patients' functional performance on a definitive and perennial basis. The objective of this study is to present the result obtained by treating 24 cases of traumatic injuries to the MTP1 joint in a midterm follow-up time. METHODS: In the period from 1999 to 2016, 24 patients were treated with MTP1 joint instability - "Expanded Turf-toe" - diagnosis. All patients were performing sports activities when they were injured: soccer (33%); martial arts (17%); running (13%); tennis (8%); olympic gymnastics (8%) and others (basketball, slalom, motorcycling, surfing, and ballet) (21%). Injuries were classified as Grade I (2 patients - 8%), Grade II (8 patients - 33%) and Grade III (14 patients - 59%) lesions. All patients with grades I and II were treated conservatively whereas those classified as grade III were treated surgically. RESULTS: After an average follow-up of 4.5 years we observed an improvement in the AOFAS hallux score from 42 to 82 points after treatment (p<0.001). The most frequent cause was axial load with various direction of stress at the first MTP. The mechanism of lesion varied among extension with hallux varism (42%), pure hyperextension (25%), extension with hallux valgism (21%), pure hyperflexion (8%) and hyperflexion with hallux valgism (4%). A separate analysis of each group showed a significant improvement in AOFAS Hallux scores after treatment: 51-84 (p<0.001) and 36-81 (p<0.001) for conservative and surgical groups, respectively. Four patients with GIII injuries (29%) and two with GII injuries (20%) did not resume their previous activities. Although pre-treatment AOFAS hallux scores were significantly different between groups, post-treatment scores were similar (p=0.615). CONCLUSIONS: Turf-toe is a serious injury that may prevent a high percentage of patients from resuming their previous physical activities. Mechanism of lesion might be varied generating a wide range of lesions that fit into the expanded concept of the Turf-toe injury. Both forms of treatment lead to satisfactory results if well conducted. The correct identification, classification, and grading of first metatarsophalangeal joint (MTP) instability helps in decision making and selection of the adequate treatment. LEVEL OF EVIDENCE: Level IV, retrospective case series.


Athletic Injuries/surgery , Foot Injuries/surgery , Hallux/surgery , Joint Instability/surgery , Metatarsophalangeal Joint/surgery , Adult , Aged , Athletic Injuries/diagnosis , Athletic Injuries/physiopathology , Female , Foot Injuries/complications , Foot Injuries/physiopathology , Hallux/diagnostic imaging , Humans , Joint Instability/diagnosis , Joint Instability/physiopathology , Magnetic Resonance Imaging , Male , Metatarsophalangeal Joint/diagnostic imaging , Metatarsophalangeal Joint/physiopathology , Middle Aged , Radiography , Range of Motion, Articular/physiology , Retrospective Studies , Young Adult
19.
Injury ; 50 Suppl 3: 63-68, 2019 Aug.
Article En | MEDLINE | ID: mdl-31378540

INTRODUCTION: Surgical treatment of displaced intra-articular calcaneal fractures using a standard extended lateral approach for plate fixation is frequently associated with substantial wound healing complications and infections. This matched pairs analysis compares the new minimally-invasive calcaneal interlocking nailing technique to standard locking plate fixation in terms of reduction capacity, complication rates, and functional outcomes. METHODS: Forty feet in 38 patients (mean patient age 52.5 years, range 27-78) were treated with calcaneal locking nail (LN)(n=20) or locking plate (LP)(n=20) and followed clinically and radiologically for 20 months. Follow-up included radiological assessments and functional evaluations including the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score and the Foot Function Index (R-FFI). RESULTS: Times for surgery were similar for both techniques (LN 93min, range 34 to 175 vs. LP 101min, range 53 to 305). Length of hospital stay was significantly lower in the LN group (7.6 days, range 3 to 14 vs. LP 11 days, range 6 to 37). Time away from work was shorter by 3.5 days in LN group. LP group had superior range of motion in plantarflexion, eversion, and inversion at follow-up, while LP patients were superior in demonstrating a secure heelstrike (79% vs. LN 58%) and fewer needed permanent walking aids. AOFAS and FFI scores revealed no differences for both groups. Radiographs indicated an adequate reconstruction in both groups, followed by a slight loss of reduction at follow-up (LP 4.7° postoperative vs. follow-up; LN 5.1°). The overall complication rate between groups was significant with 5% complications in the LN group vs. 50% in the LP group (5% deep infection, 35% impaired wound healing, 5% hardware breakage, 5% superficial wound infection; LN: 5% superficial wound infection). CONCLUSIONS: The new calcaneal interlocking nail shows promising results in terms of reduction capacity and safety. Use of the minimally invasive locking nail technique minimized the risk of postoperative wound complications and achieved superior functional outcomes compared with standard locking plate fixation via the extended lateral approach.


Calcaneus/surgery , Foot Injuries/surgery , Fracture Fixation, Internal/methods , Intra-Articular Fractures/surgery , Postoperative Complications/surgery , Adult , Aged , Bone Plates , Female , Foot Injuries/diagnostic imaging , Foot Injuries/physiopathology , Humans , Intra-Articular Fractures/diagnostic imaging , Intra-Articular Fractures/physiopathology , Male , Middle Aged , Postoperative Complications/diagnostic imaging , Postoperative Complications/physiopathology , Radiography , Range of Motion, Articular , Treatment Outcome
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