RESUMEN
Leprosy is a chronic infectious disease that has a slow evolution and is characterized by dermatoneurological involvement. The health challenges surrounding this disease are closely related to the stigma that results from the physical disabilities it causes. This is due to its high rate of late diagnosis and the peculiar deformities that occur in its advanced stage. Evaluate the clinical and epidemiological aspects of patients with plantar lesions who were treated for leprosy in a dermatology referral unit. This is a cross-sectional exploratory field study that was conducted at the Reference Center in Tropical Dermatology and Venereology Alfredo da Matta (FUHAM), in Manaus, Amazonas, Brazil. We evaluated 36 patients with disabilities as a result of leprosy and who had plantar lesions. The most common ulcer site was the medial region of the plantar surface, which presented dryness and maceration with yellowish seropurulent exudate, fibrinous tissue and grade 2 depth. The study made it possible to observe the evolution of plantar ulcers resulting from the disease process, then evaluate them and discuss recommendations regarding the treatment and prevention of this type of physical disability.
Asunto(s)
Lepra , Humanos , Lepra/epidemiología , Lepra/diagnóstico , Lepra/complicaciones , Estudios Transversales , Masculino , Femenino , Adulto , Brasil/epidemiología , Persona de Mediana Edad , Úlcera del Pie/diagnóstico , Úlcera del Pie/epidemiología , Úlcera del Pie/etiología , Úlcera del Pie/terapia , Adulto Joven , Personas con Discapacidad/estadística & datos numéricos , Anciano , AdolescenteRESUMEN
Resumen: Las úlceras de pie diabético (UPD) generan un alto costo para el paciente y el sistema de salud. Una deficiente vascularización, la inhibición de la generación de factores de crecimiento y la migración celular, entre otros factores, influyen en su cronicidad. Los factores de crecimiento derivados de las plaquetas (PDGF) estimulan la quimiotaxis, la neovascularización y la regeneración tisular. Objetivo: evaluar la efectividad de una formulación de plasma rico en plaquetas autólogo (PRP) como una modalidad complementaria para el tratamiento de UPD, valorando su seguridad y efectos adversos. Materiales: estudio observacional. Se aplicó PRP a seis pacientes con UPD crónicas, Wagner II, III, con una media en el retraso de la cicatrización de 94 semanas. Se administró mediante punción y como gel sobre la lesión una vez por semana hasta el cierre de la úlcera o durante12 semanas. Las UPD se analizaron con respecto al área y su progresión mediante Mobile Wound Analyzer (MOWA), software de análisis de imágenes de úlceras. El porcentaje de reducción del área se calculó entre la medición inicial y la semana 12. Como criterio de mejoría se eligió una reducción >70% de la lesión. Resultados: predominó el sexo masculino con una media de edad de 53 años ± 7,3. Luego de 12 semanas de tratamiento, se reportó una reducción media del tamaño de la úlcera de 78%, con dos cicatrizaciones completas y dos en 99%. Un paciente recibió una amputación luego de presentar infección no controlada. Conclusión: la aplicación del PRP mejoró la regeneración de tejidos, acortando la duración de la úlcera, promoviendo su curación sin efectos adversos, al tiempo que eliminó la necesidad de procedimientos de manejo en una úlcera crónica.
Summary: Diabetic foot ulcers imply high expenditure for both patients and the health system. Vascular impairment, growth factor inhibition and cell migration, among other factors, affect the chronicity of the condition. Platelet-derived growth factors (PDGFs) stimulate chemotaxis, neovascularization and tissue regeneration. Objective: to evaluate effectiveness of a formulation of autologous platelet-rich plasma to complement the treatment of diabetic foot ulcer, assessing safety and adverse effects. Material: observational study. Platelet rich plasma was applied to six patients with chronic diabetic foot ulcer Wagner II, III, with an average delayed healing of 94 weeks. PRP gel was administered by puncture technique on the lesion, once a week until the ulcer healed or for 12 weeks. Diabetic foot ulcers were analysed in regards to surface area and progression through the Mobile Wound Analyzer (MOWA) software to analyse ulcer images. The area reduction percentage was calculated comparing the initial measurement and that of week 12. The improvement criteria was defined in a reduction that is >70% of the lesion. Results: men prevailed with an average age of 53 years ± 7.3. After 12 weeks of treatment an average reduction of 78% of the size of the ulcer was reported, two complete healings and two 99% healed. One patient required amputation because of uncontrolled infection. Conclusion: the application of PRP improved tissue regeneration and shortened the duration of the ulcer, promoting healing with no adverse effects, and it likewise eliminated the need for procedures to handle chronic ulcers.
Resumo: As úlceras do pé diabético (UPD) geram alto custo para o paciente e para o sistema de saúde. A vascularização deficiente, a inibição da geração de fatores de crescimento e migração celular, entre outros fatores, influenciam sua cronicidade. Os fatores de crescimento derivados de plaquetas (PDGF) estimulam a quimiotaxia, a neovascularização e a regeneração de tecidos. Objetivo: avaliar a eficácia de uma formulação autóloga de plasma rico em plaquetas (PRP) como modalidade complementar para o tratamento da UPD, avaliando sua segurança e efeitos adversos. Materiais: estudo observacional. O PRP foi aplicado a 6 pacientes com UPD crônica, Wagner II, III, com um atraso médio na cicatrização de 94 semanas. Foi administrado por punção e como gel sobre a lesão uma vez por semana até o fechamento da úlcera ou por 12 semanas. As UPD foram analisadas em relação à área e sua progressão, utilizando o software de análise de imagem de úlcera Mobile Wound Analyzer (MOWA). A redução percentual da área foi calculada entre a medição inicial e a semana 12. Como critério de melhora, optou-se pela redução > 70% da lesão. Resultados: predominou o sexo masculino com média de idade de 53 ± 7,3 anos. Após 12 semanas de tratamento, foi relatada uma redução média no tamanho da úlcera de 78%, sendo 2 com cicatrização completa e 2 em 99%. Um paciente foi amputado após desenvolver infecção descontrolada. Conclusão: a aplicação do PRP melhorou a regeneração tecidual, encurtando o tempo de duração da úlcera, promovendo sua cicatrização sem efeitos adversos, ao mesmo tempo que eliminava a necessidade de procedimentos de manejo na úlcera crônica.
Asunto(s)
Pie Diabético/terapia , Plasma Rico en Plaquetas , Úlcera del Pie/terapiaRESUMEN
Introducción: Las úlceras del pie diabético resultan las complicaciones más frecuentes en las personas con diabetes. Se conocen diferentes formas de tratamiento para esta enfermedad, con más o menos efectividad, pero no resuelven el problema en la totalidad de los casos. El estimulador eléctrico Stimul W® y el medicamento Heberprot-P® se han empleado, de manera independiente y con resultados satisfactorios, como alternativas para el tratamiento de estas lesiones. Comprobar si la acción combinada de ambos procedimientos permite alcanzar mejores resultados, permitiría contribuir a resolver un problema de alta prevalencia mundial. Objetivo: Exponer el resultado de la aplicación de la combinación del estimulador Stimul W® y el medicamento Heberprot-P® en el tratamiento de un paciente con úlcera del pie diabético. Presentación del caso: Paciente masculino de 69 años de edad, con diabetes mellitus de tipo 2, que presentaba una úlcera del pie diabético en la parte externa del pie derecho, con abundante tejido necrótico en forma de fístula en la base de los dos dedos restantes y falta de granulación. Los tratamientos anteriores no dieron el resultado esperado. Se decidió, como terapia de curación, aplicar durante 12 sesiones la combinación del estimulador Stimul W® y el medicamento Heberprot-P®. Conclusiones: Se logró la cicatrización de la lesión, al obtener un 100 por ciento de tejido de granulación y la disminución significativa de sus dimensiones, lo que mostró que la terapia aplicada constituye una alternativa para el tratamiento de este tipo de úlcera(AU)
Introduction: Diabetic foot ulcers are the most frequent complications in people with diabetes. Different forms of treatment for this disease are known, with more or less effectiveness; but they do not solve the problem in all cases. The electrical stimulator Stimul W® and the drug Heberprot-P® have been used independently, and with satisfactory outcomes, as alternatives for the treatment of these lesions. Checking whether the combined action of both procedures allows to achieve better outcomes would contribute to solve a problem of high worldwide prevalence. Objective: To present the outcomes of applying the combination of the stimulator Stimul W® and the drug Heberprot-P® for treating a patient with diabetic foot ulcer. Case presentation: A 69-year-old male patient, with type 2 diabetes mellitus, who presented with a diabetic foot ulcer on the outside of the right foot, with abundant necrotic tissue in the form of a fistula at the base of the two remaining toes and lack of granulation. The previous treatments did not permit the expected outcomes. It was decided, as a healing therapy, to apply the combination of the stimulator Stimul W® and the drug Heberprot-P® for twelve sessions. Conclusions: Healing of the lesion was achieved by obtaining 100 percent granulation tissue and a significant reduction in its dimensions, which showed that the applied therapy constitutes an alternative for the treatment of this type of ulcer(AU)
Asunto(s)
Humanos , Masculino , Anciano , Dedos del Pie/lesiones , Úlcera del Pie/terapia , Pie Diabético , Diabetes Mellitus Tipo 2/etiologíaRESUMEN
Introducción: El Heberprot-P® es un medicamento novedoso y único en su tipo, prescrito para la terapia de la úlcera del pie diabético. Objetivo: Evaluar la frecuencia y las características de la recidiva de úlcera del pie en pacientes diabéticos tratados con Heberprot-P®. Métodos: Se realizó una investigación descriptiva-retrospectiva. La población estuvo constituida por 16 pacientes con recidiva de úlcera de pie diabético de los 841 tratados con Heberprot-P® en policlínicos y hospitales de la provincia de Matanzas desde enero hasta diciembre de 2018. Las variables revisadas fueron llevadas a una base de datos, y los resultados obtenidos se tabularon y se expresaron en frecuencias absolutas y relativas. Se respetaron las consideraciones éticas requeridas para este estudio. Resultados: El grupo de edades 61-75 años y los diabéticos de tipo 2 fueron los más afectados, y no existieron diferencias entre ambos sexos. El pie diabético neuropático con una severidad Wagner 2 se manifestó con mayor frecuencia. Asimismo, a partir de la primera lesión y la recidiva se observó un gran número de pacientes con la enfermedad entre las 13 y 16 semanas, y al 56,2 por ciento de estos se les administró, durante la primera lesión, de 6 a 12 dosis de Heberprot-P®. El cierre total de la lesión en el desenlace fue lo más encontrado en la población de estudio, y el 1,9 por ciento de los pacientes tratados presentó una recidiva de esta. Conclusiones: Quedaron expuestas la frecuencia y las características de la recidiva de la úlcera del pie en los pacientes diabéticos tratados con Heberprot-P®(AU)
Introduction: Heberprot-P® is a novel medicine, unique among its kind, prescribed for diabetic foot ulcer therapy. Objective: To evaluate frequency and characteristics of foot ulcer recurrence among diabetic patients treated with Heberprot-P®. Methods: A descriptive-retrospective research was carried out. The study population consisted of 16 patients with diabetic foot ulcer recurrence from among the 841 treated with Heberprot-P® in polyclinics and hospitals in Matanzas Province from January to December 2018. The variables reviewed were taken to a database, and the results obtained were represented in charts and expressed in absolute and relative frequencies. The ethical considerations required for this study were respected. Results: The age group 61-75 years and type 2 diabetic patients were the most affected. There were no differences between both sexes. Neuropathic diabetic foot with Wagner 2 severity appeared more frequently. Likewise, after the first injury and recurrence, a large number of patients with the disease were observed at 13-16 weeks, 56.2 percent of whom, were administered, during the first injury, 6-12 doses of Heberprot-P®. The total closure of the lesion was the most found outcome in the study population, and 1.9 percent of the treated patients presented recurrence of this. Conclusions: The frequency and characteristics of foot ulcer recurrence in diabetic patients treated with Heberprot-P® were exposed(AU)
Asunto(s)
Humanos , Masculino , Femenino , Persona de Mediana Edad , Anciano , Preparaciones Farmacéuticas , Úlcera del Pie/terapia , Pie Diabético/complicaciones , Diabetes Mellitus Tipo 2 , RecurrenciaAsunto(s)
Humanos , Femenino , Anciano , Arteriopatías Oclusivas , Ejercicio Físico , Úlcera del Pie/complicaciones , Enfermedad Arterial Periférica/complicaciones , Enfermedad Arterial Periférica/rehabilitación , Úlcera del Pie/prevención & control , Úlcera del Pie/terapia , Sarcopenia , Claudicación IntermitenteRESUMEN
Introdução: A úlcera plantar por hanseníase é uma lesão no pé resultante da falta de sensibilidade plantar. O objetivo é descrever o tratamento realizado em portadores de úlceras plantares por hanseníase. Métodos: Estudo de prontuários de portadores de úlcera plantar atendidos no Hospital Sarah em Brasília, de 2006 a 2016, quanto ao sexo, idade, etiologia, localização e tratamento. Resultados: Foram atendidos 27 pacientes, 17(62,96%) homens e 10 (37,04%) mulheres, procedentes de Goiás e DF, na faixa etária de 41 a 60 anos (40,74%). Todos necessitaram de um ou mais procedimentos cirúrgicos. Conclusão: Observou-se maior frequência no sexo masculino, grau avançado, localizadas no primeiro artelho. Todos necessitaram de procedimentos cirúrgicos e não cirúrgicos, evoluindo com cicatrização completa da ferida, amputação transtibial em um caso e de artelhos em sete casos, e 90% dos casos apresentaram recorrência da úlcera após um ano.
Introduction: Leprosy-induced plantar ulcers result from a lack of plantar sensitivity. Objective: This study aimed to describe the treatment provided to patients with leprosy-induced plantar ulcers. Methods: We retrospectively reviewed the medical records of patients with plantar ulcers treated at Sarah Hospital in Brasilia from 2006 to 2016 and collected information about sex, age, etiology, location, and treatment. Results: A total of 27 patients (17 [62.96%] men, 10 [37.04%] women; 40.74% were aged 4160 years) were treated from Goiás and the Federal District. All required ≥1 surgical procedure. Conclusion: A higher frequency of advanced grade was observed in men, primarily on the first toe. All needed surgical and non-surgical procedures and achieved complete wound healing. Transtibial amputation was required in 1 case and toe amputation in 7 cases; 90% patients developed ulcer recurrence after 1 year.
Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Historia del Siglo XXI , Rehabilitación , Terapéutica , Tratamiento Terciario , Registros Médicos , Úlcera del Pie , Lepra , Rehabilitación/métodos , Rehabilitación/estadística & datos numéricos , Terapéutica/métodos , Terapéutica/estadística & datos numéricos , Tratamiento Terciario/métodos , Tratamiento Terciario/estadística & datos numéricos , Registros Médicos/normas , Registros Médicos/estadística & datos numéricos , Úlcera del Pie/cirugía , Úlcera del Pie/complicaciones , Úlcera del Pie/terapia , Lepra/cirugía , Lepra/complicaciones , Lepra/terapiaRESUMEN
Wound healing is a perfectly coordinated cascade of cellular, molecular, and biochemical events which interact in tissue reconstitution. Chronic diseases such as pressure ulcers (PU) and diabetes mellitus (DM) are considered risk factors for wound healing. Patients with such diseases often have higher sepsis, infection, and complication rates, since they have revascularization inhibition and low growth factor expression. Thus, latex biomembrane (LBM), a biocompatible material, derived from the latex of the rubber tree (Hevea brasiliensis) appears to create tendencies as an angiogenic-inducing tissue healing agent and as biomaterial, resulting from its structural qualities and its low cost when compared to conventional treatments. Therefore, this work aims at summarizing the results, experiments, and scientific findings that certify or recommend the use of LBM as a new technique to be applied effectively in the treatment of wounds. An integrative review was held in the BIREME, LILACS, Burns, MEDLINE, PubMed, and SciELO databases, from 2000 to 2016, using the following descriptors: "healing," "diabetes mellitus," "wounds," and "latex membrane." As a result, 600 experiments (out of 612) presented satisfactory results; however, 33% of the cases received explicit recommendations, 11% required more studies on the subjects, and 1% was denied. On the other hand, half of the studies did not expressly endorse its use, despite presenting satisfactory results. The LBM was characterized as a good therapeutic alternative in cases of wounds, including chronic diseases, such as diabetes mellitus and PU, due to its relevant potential for wound healing stimulation, acceleration of cell tissue mending and revascularization, or the reestablishment of angiogenic functions (creation of new blood vessels). The LBM was also confirmed to be safe as a biocompatible material whose structural qualities (elasticity, adaptability, impermeability, and possibility of suture), devoid of toxicity, allowed interaction between tissues and presented no hypersensitivity inducer and no antimicrobial effect.
Asunto(s)
Materiales Biocompatibles/uso terapéutico , Pie Diabético/terapia , Úlcera del Pie/terapia , Hevea/química , Látex/uso terapéutico , Cicatrización de Heridas , Animales , Productos Biológicos/uso terapéutico , Ortesis del Pié , Humanos , Ensayo de Materiales , Resultado del TratamientoRESUMEN
Infection plays a critical role in health care and impacts the cost of the treatment of diabetic foot ulcers (DFU). To examine the cost reduction associated with the multidisciplinary treatment of infected DFU (IDFU) by obtaining early (ie, within 48 hours of admission) microbiological culture results, a descriptive, longitudinal study was conducted. Data were collected prospectively from patient medical charts of a cohort of 67 patients (mean age, 56.14 ± 12.3 years; mean duration of diabetes, 14.95 ± 8 years) with IDFU treated at a Mexican public health facility from January 1 to April 30, 2010. Information included demographic data (age, gender, marital status, time elapsed since first diagnosis of diabetes mellitus type 2 [DM2]), and the following clinical records: Wagner classification, bacterium type, antimicrobial resistance, length of hospital stay, and the antibiotic schedule utilized, as well as number and type of laboratory tests, medications, intravenous therapy, surgical and supportive treatment, type and number of specialists, and clinical outcome. Microcosting was used to calculate the unit cost of each medical treatment element. Using the Monte Carlo and Markov predictive simulation economical models, cost reduction associated with early identification of the specific microorganism through bacterial culture in IDFU was estimated. Based on the statistical results, differences between real and estimated costs when including early microbiological culture were identified and the number and type of most common species of infectious bacteria were detected. The total cost observed in the patient cohort was $502 438.04 USD, mean cost per patient was $7177.69 ± $5043.51 USD, and 72.75% of the total cost was associated with the hospital stay length. The cost of the entire treatment including antibiotics was $359 196.16 USD; based on the simulation of early microbiological culture, the model results showed cost could be reduced by 10% to 25% (in this study, the cost could be as low as $304 624.63 USD). The use of early microbiological cultures on IDFU to determine the appropriate antibiotic can reduce treatment costs by >30% if hospital stay is part of the consideration.
Asunto(s)
Costo de Enfermedad , Técnicas de Cultivo/economía , Úlcera del Pie/economía , Factores de Tiempo , Adulto , Anciano , Técnicas de Cultivo/métodos , Técnicas de Cultivo/estadística & datos numéricos , Diabetes Mellitus Tipo 2/complicaciones , Diabetes Mellitus Tipo 2/economía , Diabetes Mellitus Tipo 2/terapia , Pie Diabético/economía , Pie Diabético/terapia , Femenino , Úlcera del Pie/terapia , Hospitales Públicos/organización & administración , Hospitales Públicos/estadística & datos numéricos , Humanos , Estudios Longitudinales , Masculino , México , Persona de Mediana Edad , Modelos Estadísticos , Estudios ProspectivosRESUMEN
La diabetes mellitus constituye un problema sanitario con una importante repercusión social y económica. El pie diabético es una complicación crónica prevenible y aún es la causa de la mayoría de las amputaciones no traumáticas. Se presenta este caso con una paciente de 61 años de edad y 16 años de evolución de su enfermedad de base, con una lesión en el dorso del pie izquierdo en estadio de Warner IV a la que se le coloco Heberprot-p intralesional, con solo tres aplicaciones y curas de seguimiento durante 3 meses, lográndose la remisión total de la lesión(AU)
Diabetes mellitus is a sanitary problem with an important social and cost-reducing repercussion constitutes. The diabetic foot is a chronic preventable complication and still nowadays it is the cause of the majority of amputations not traumatic. You encounter this case with a patient of 61 elderly years and 16 years of evolution of his disease of base, with a lesion in the reverse of the left foot at stadium of Warner IV that I applied her Heberprot-p intralesional, with only three applications and follow-up cures during 3 months, getting the total remission of the lesion(AU)
Asunto(s)
Humanos , Femenino , Pie Diabético/terapia , Diabetes Mellitus/terapia , Factores de Riesgo , Úlcera del Pie/terapiaRESUMEN
São apresentadas, nessa separata, as principais orientações sobre a atenção às complicações do pé diabético. A neuropatia, com suas diversas apresentações que acometem os membros inferiores dos diabéticos, as lesões da doença arterial obstrutiva periférica (DAOP), as múltiplas apresentações da infecção do pé diabético, e, principalmente, os cuidados preventivos que possam impedir o estabelecimento ou a evolução dessas complicações são tratados de forma sistemática e simplificada, visando a atenção integral desses doentes. Especial cuidado é dado às orientações diferenciadas para os diversos níveis de atenção nos serviços públicos de saúde, porta de entrada virtual de 80% dos infelizes portadores dessa complicação. São aqui apresentados modelos de atenção e sugeridos protocolos que podem contribuir para a efetiva redução do número de amputações, internações e óbitos de diabéticos com complicações nos membros inferiores.
Asunto(s)
Humanos , Masculino , Anciano , Enfermedades Vasculares Periféricas/cirugía , Enfermedades Vasculares Periféricas , Enfermedades Vasculares Periféricas/rehabilitación , Neuropatías Diabéticas/diagnóstico , Neuropatías Diabéticas/prevención & control , Neuropatías Diabéticas/sangre , Pie Diabético/terapia , Úlcera del Pie/patología , Úlcera del Pie/prevención & control , Úlcera del Pie/terapia , Amitriptilina/administración & dosificación , Amputación Quirúrgica/rehabilitación , Extremidad Inferior/patología , Espectroscopía de Resonancia Magnética , Factores de Riesgo , Tomografía Computarizada de Emisión/métodosRESUMEN
A infecção do pé é uma importante causa de morbidade em pacientes com diabetes melito, sendo responsável pela maioria dos casos de amputação não traumática de membros inferiores. A ulceração, secundária principalmente à neuropatia diabética, deformidade e trauma, é o principal fator de risco para infecção. Prevenção e identificação precoce dessas alterações, com tratamento apropriado, constituem ferramentas essenciais para diminuir a morbidade relacionada. Neste artigo, relatamos o caso de um paciente com diabetes melito tipo 2 e infecção de pé diabético, com predominância de componente neuropático, e descrevemos o protocolo assistencial recomendado pelo Serviço de Endocrinologia do Hospital de Clínicas de Porto Alegre (HCPA).
Infection of the foot is a major cause of morbity in patients with diabetes mellitus and is responsible for most cases of nontraumatic amputation of lower limbs. The ulceration, mainly secondary to diabetic neuropathy, deformity and trauma, is the main risk factor for infection. Prevention and early identification of these changes, along with its appropriate treatment are essential tasks to reduce morbidity related. We report a case of a patient with type 2 diabetes mellitus and infection of diabetic foot, mainly presenting neuropathy, and describe the protocol of care recommended by the Endocrinology Unit of the Hospital de Clínicas de Porto Alegre (HCPA).
Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Complicaciones de la Diabetes/diagnóstico , Complicaciones de la Diabetes/terapia , Pie Diabético/diagnóstico , Pie Diabético/terapia , Osteomielitis/diagnóstico , Osteomielitis/terapia , Úlcera del Pie/diagnóstico , Úlcera del Pie/terapiaRESUMEN
Chronic complications of diabetes are the most important cause of morbidity of the disease, which constitutes a major public health problem. Patientes with diabetes are more prone to develop premature atherosclerotic disease in the lower extremities, which leads to frequent hospitalizations for common lower extremity amputations... This report offers guidelines for the management of a foot, which is threatened, with loss of the blood supply due to impairment of the circulation of the lower limbs, in diabetic patients.
Asunto(s)
Humanos , Neuropatías Diabéticas/patología , Prevención Primaria , Pie Diabético/diagnóstico , Pie Diabético/prevención & control , Pie Diabético/terapia , Prevención Secundaria , Úlcera del Pie/prevención & control , Úlcera del Pie/terapiaRESUMEN
La afección del pié en los pacientes con diabetes constituye por su importancia una entidad en si misma. En el espectro de su afectación encontraremos desde simples cambios en la sensibilidad y el trofismo de la piel, hasta úlceras de diferente magnitud, lesiones necróticas y osteomielitis, que pueden conducir a amputaciones y aún, comprometer la vida del paciente. En una entrega anterior desarrollamos aspectos generales del pié en las personas con diabetes y en particular, el abordaje de las ulceras no infectadas. En esta entrega se profundiza sobre el abordaje y manejo de las infecciones del pie, particularmente de las lesiones ulceradas y la osteomielitis.
Foot involvement in diabetic patients is an entity by itself. The spectrum of Its affection range from skin changes in sen-sitivity and trofism to ulcers of different magnitude, necrotic lesions and osteomyelitis, which can lead to amputations andeven compromise the patient's life .In a previous issue, general aspects of diabetic foot, and management of non-infect-ed ulcers, in particular, were reviewed. In this issue we deepens on addressing the evaluation and management of dia-betic foot infections, particularly of ulcerated lesions, and osteomyelitis
Asunto(s)
Humanos , Masculino , Femenino , Complicaciones de la Diabetes , Diagnóstico Diferencial , Infecciones de los Tejidos Blandos , Osteomielitis , Pie Diabético , Pie Diabético/terapia , Úlcera del Pie/complicaciones , Úlcera del Pie/diagnóstico , Úlcera del Pie/etiología , Úlcera del Pie/terapiaAsunto(s)
Envejecimiento/patología , Anemia de Células Falciformes/complicaciones , Anemia de Células Falciformes/patología , Adulto , Anciano , Anemia de Células Falciformes/fisiopatología , Antidrepanocíticos/uso terapéutico , Transfusión Sanguínea , Femenino , Úlcera del Pie/etiología , Úlcera del Pie/fisiopatología , Úlcera del Pie/terapia , Humanos , Hidroxiurea/uso terapéutico , Fallo Renal Crónico/etiología , Fallo Renal Crónico/fisiopatología , Fallo Renal Crónico/terapia , Masculino , Persona de Mediana Edad , Necrosis/etiología , Necrosis/fisiopatología , Necrosis/terapia , Trinidad y TobagoRESUMEN
PURPOSE: Propose a new and alternative surgical procedure in order to aid on treatments of chronic ulcers with non-arterial etiology in the lower limbs, especially those that reoccurs and accomplish of dermatosclerosis and skin contractures determining ankle and foot limits. METHODS: It describes a medical case regarding a female, 54 years old, with a pre-existing ulcer (sixteen years) on her left leg. Despite of conventional treatments such as curatives, compressive therapy and surgeries, the ulcer on her leg was not cured for three years. The skin dermatosclerosis on her foot and ankle limited her mobility tremendously. The surgery involved the debridement of the ulcers, local phlebectomies and the correction of her scar contraction by a transversal escharotomies. Conventional procedures were applied in pre and post-surgery. RESULTS: After twelve weeks, the ulcer was completely healed by second intention. Despite the odds, she regained sustainable mobility in her foot and ankle, allowing this patient to wear medical elastic socks. Reoccurrences of the ulcer did not occur during the two years post-surgery. CONCLUSION: The transversal escharotomies may favor the healing of non-arterial chronic ulcers in the lower limbs, impeding perpetual mechanisms of this sort. For example, the ankle and foot limitation determinates in secondary scars, skin contractures, dermatosclerosis that produce the failure in the muscular calf-pump with deterioration in the ascending venous propulsion.(AU)
OBJETIVO: Apresentar uma nova alternativa cirúrgica para auxiliar o tratamento de úlceras crônicas de etiologia não arterial em membros inferiores, especialmente aquelas com recidivas e complicadas por contraturas de pele, limitando movimentos do pé e tornozelo. MÉTODOS: Descrição de caso de uma paciente portadora de úlcera em perna esquerda com dezesseis anos de evolução, múltiplas recidivas, sem cicatrização há três anos apesar de curativos convencionais, terapias compressivas e cirurgias. As contraturas cicatriciais e a dermatoesclerose local limitavam a marcha pela redução da mobilidade do pé e tornozelo. A cirurgia realizada foi o debridamento tangencial da úlcera, flebectomias locais e a correção das contraturas de pele por meio das escarotomias transversais. Após a cirurgia foram mantidos os mesmos padrões de curativos e a terapia compressiva utilizada no pré-operatório. RESULTADOS: Houve cicatrização completa da úlcera, por segunda intenção, doze semanas após a cirurgia com ganho importante na amplitude dos movimentos do pé e tornozelo, permitindo normalização da marcha e adaptação ao uso de meias elásticas terapêuticas. Não houve recidiva em dois anos de acompanhamento pós-operatório. CONCLUSÃO: Esta técnica parece favorecer a cicatrização de úlceras crônicas de etiologia não arterial atuando em mecanismos perpetuadores do processo, como, por exemplo, a limitação da propulsão venosa pela musculatura da panturrilha determinada por contraturas cicatriciais e pela dermatoesclerose do pé e tornozelo.(AU)
Asunto(s)
Humanos , Enfermedades de la Piel/terapia , Enfermedades de la Piel/cirugía , Úlcera del Pie/terapia , Úlcera del Pie/cirugía , Cicatrización de Heridas/fisiología , Procedimientos Quirúrgicos Operativos/métodosRESUMEN
En el presente trabajo se realiza una revisión bibliográfica de los principales tratamientos médicos utilizados en el mal perforante plantar. (AU)