Agrandamiento gingival inducido por fenitoínas / Phenytoin induced gingival enlargement

Se entiende por agrandamiento gingival el incremento en masa y volumen del tejido gingival. Se considera una condición benigna de la cavidad oral, por lo general de manejo rutinario, que logra regularse con medidas simples de control del biofilm microbiano. El agrandamiento gingival puede ser producido por diversas condiciones clínicas, hereditarias, deficiente higiene oral o fármacos. La epilepsia afecta a 1% de la población mundial y requiere el uso de fármacos antiepilépticos o anticonvulsivantes para lograr su control, dentro de éstos la fenitoína actúa como un bloqueador selectivo de los canales de sodio sensibles al voltaje y constituye uno de los fármacos más empleados por su capacidad en el control de crisis focales y generalizadas. La fenitoína se ha relacionado con los agrandamientos gingivales como uno de sus efectos adversos, los cuales se incluyen dentro de las enfermedades por fármaco inducidas en la cavidad oral. El objetivo de este artículo es brindar la información necesaria sobre el manejo correcto de pacientes con agrandamiento gingival producido por fenitoínas y a la vez poder conocer las consecuencias de estos fármacos en la cavidad oral (AU)

Gingival enlargement means the increase in mass and volumen of the gingival tissue. It is considered a benign condition of the oral cavity, usually of routine management, wich can be regulated with simple measures of biofilm control. The gingival enlargement can be produced by diverse clinical conditions, hereditary deficient oral higiene or drugs. Epilepsy affects 1% of the world population and requires the use of antiepileptic or anticonvulsant drugs to achieve its control, within these phenytoin acts as selective blocker or voltage ­ sensitive sodium channels and is one of the most used grugs for its ability to control focal and generalized crises. Phenytoin has been linked to gingival enlargement as one of its adverse effects which is included within the drug diseases induced in the oral cavity. The objective of this article is to provide the necessary information on the correct managment of patients with gingival enlargemen produced by phenytoins and at the same time to know the consequences of these drugs in the oral cavity (AU)

Hiperplasia gingival fibrosa asociada a incisivo central superior retenido / Fibrous gingival hiperplasia associated with upper central incisor retained / Hiperplasia gengival fibrosa associada a incisivo central superior retido

RESUMEN Se describió el caso clínico de un adolescente de 12 años de edad, atendido en el Departamento de Ortodoncia de la Clínica Estomatológica Provincial "Mártires del Moncada" de Santiago de Cuba, al cual se le diagnosticó retención del incisivo central superior derecho hace más de dos años y para la cual recibió tratamiento con aparatología fija previo entorche del diente y seguimiento clínico-radiográfico. Durante el proceder ortodóncico, es remitido al Departamento de Periodoncia por presentar en la zona de dicho diente un aumento de volumen de color rosa coral, de consistencia dura y aspecto fibroso, que imposibilitó la incorporación definitiva del diente en su arco y plano de oclusión. Se realizaron los exámenes complementarios correspondientes, se diagnosticó hiperplasia gingival fibrosa localizada y se realizó tratamiento quirúrgico (gingivectomía), lo que permitió llevar a feliz término el tratamiento ortodóncico sin ninguna implicación psicológica y social para el paciente. La poca frecuencia de aparición de este tipo de lesión asociada a la retención de incisivos centrales superiores motivó el presente informe de caso.

ABSTRACT It was described a clinical case of a 12-year-old adolescent, treated at the Orthodontic Department of the Provincial Stomatological Clinic "Mártires del Moncada" in Santiago de Cuba, who was diagnosed with retention of the upper right central incisor more than two years ago and for which he received treatment with fixed appliances prior to tooth straightening and clinical-radiographic follow-up. During the orthodontic procedure, he was referred to the Department of Periodontics because he had a coral pink increase in volume in the area of that tooth, with a hard consistency and fibrous appearance, which made it impossible to definitively incorporate the tooth into its arch and occlusion plane. The corresponding complementary examinations were carried out, localized fibrous gingival hyperplasia was diagnosed and surgical treatment (gingivectomy) was performed, which allowed the successful completion of orthodontic treatment without any psychological or social implications for the patient. The rare occurrence of this type of injury associated with retention of upper central incisors motivated this case report.

RESUMO O caso clínico de um adolescente de 12 anos de idade, atendido no Departamento de Ortodontia da Clínica Estomatológica Provincial "Mártires del Moncada" de Santiago de Cuba, diagnosticado com retenção do incisivo central superior direito, foi descrito mais de dois anos e para os quais ele recebeu tratamento com aparelhos fixos antes do bloqueio dentário e monitoramento clínico-radiográfico. Durante o procedimento ortodôntico, é encaminhado ao Departamento de Periodontia por apresentar na área do referido dente um aumento no volume rosa coral, de consistência dura e aparência fibrosa, o que impossibilitou a incorporação definitiva do dente em seu arco e plano de oclusão. Foram realizados os exames complementares correspondentes, diagnosticada hiperplasia gengival fibrosa localizada e realizado tratamento cirúrgico (gengivectomia), o que permitiu o tratamento ortodôntico sem envolvimento psicológico e social do paciente. A baixa frequência de ocorrência desse tipo de lesão associada à retenção dos incisivos centrais superiores motivou este relato de caso.

Corrección quirúrgica en una adolescente con hiperplasia gingival hereditaria / Surgical correction in an adolescent with hereditary gingival hyperplasia

Se describe el caso clínico de una adolescente que fue atendida en la consulta de Periodoncia del Hospital General Docente Dr Juan Bruno Zayas Alfonso de Santiago de Cuba, por presentar agrandamiento de las encías desde hacía más de un año, lo que le dificultaba la masticación de los alimentos y, por tanto, le producía trastornos digestivos transitorios, además de afectar su estética. Luego de realizados los exámenes físico y complementarios, se estableció el diagnóstico presuntivo de hiperplasia gingival hereditaria o familiar y se indicó el tratamiento, que incluyó 3 fases: la inicial, la correctiva quirúrgica y la de soporte periodontal. En la fase quirúrgica se tomó una muestra hística cuyo análisis anatomopatológico confirmó el diagnóstico presuntivo inicial

The case report of an adolescent that was assisted in the Periodontics Service of Dr Juan Bruno Zayas Alfonso Teaching General Hospital in Santiago de Cuba is described. He presented enlargement of the gums for more than a year, which made mastication of foods difficult and therefore, transitory digestive dysfunctions took place, besides affecting her aesthetics. After the physical and complementary tests, the presumptive diagnosis of hereditary or family gingival hyperplasia was established and the treatment was indicated into 3 phases: initial phase, surgical corrective phase and that of periodontal support. In the surgical phase a tissue sample was taken which pathologic analysis confirmed the initial presumptive diagnosis

Cryotherapy for localized juvenile spongiotic gingival hyperplasia: preliminary findings on two cases.

BACKGROUND: Localized juvenile spongiotic gingival hyperplasia (LJSGH) is a distinct subtype of inflammatory gingival hyperplasia that shows lack of response to traditional periodontal treatment, and after surgical excision, recurrence rate of 6-16% has been reported. CASE REPORT: Two girls (11- and 9-year-old) with multifocal red patches along the maxillary and mandibular labial gingiva showed no regression of the lesions after basic periodontal treatment. Surgical excision of focal lesion in each case was performed, which showed typical features of LJSGH. In both cases, the lesions presented recurrence. Hence, cryotherapy sessions in all lesions were performed. CONCLUSION: Cryotherapy appears to be successfully in LJSGH and well received by paediatric patients.

Gingivoplastia y frenillectomía labial con láser de alta intensidad: presentación de caso / Gingivoplasty and labial frenectomy with high intensity laser: presentation of a case

En los últimos años la estética se ha convertido en motivo de consulta odontológica frecuente. Los pacientes creen que la estética de la sonrisa depende de los dientes; sin embargo, al realizar la evaluación clínica, el profesional puede detectar inconformidad estética del paciente condicionada por factores del medio bucal como los tejidos blandos del periodonto de protección, específicamente la encía aumentada o la inserción muy baja de la mucosa de los frenillos labiales, lo que puede ocasionar que los pacientes manifiesten ver sus dientes de tamaño reducido; además al sonreír pueden exponer gran cantidad de encía. A continuación se expone el caso de una paciente mujer que acude a consulta por inconformidad estética en la sonrisa y tamaño dental; tras la valoración intraoral se diagnostica gingivitis localizada asociada a placa bacteriana y presencia de frenillo papilar alargado, provocando apariencia de dientes cortos o pequeños. Se decide realizar procedimiento quirúrgico mínimamente invasivo para reposicionar los tejidos blandos y mejorar la armonía, respetando espacios biológicos, utilizando terapia con láser de alta intensidad considerando las ventajas de su uso como tiempo de intervención menor, no requerir anestesia local, menor sangrado, tiempo de cicatrización más corto y haciendo innecesario el uso de suturas al compararle con la cirugía convencional con bisturí. Al finalizar el procedimiento la paciente manifiesta satisfacción y ausencia de dolor. Tras control posquirúrgico a los 15 días se aprecia ausencia de edema en el tejido gingival, reposicionamiento de la inserción del frenillo labial superior y borde libre de encía marginal en los órganos dentarios anterosuperiores reposicionados en sentido apical.

In recent years, aesthetics has become a common reason for a dental visit. Patients believe that the aesthetics of the smile depends on the teeth. However, when the clinical evaluation is carried out, the professional can also detect aesthetic dissatisfaction of a patient, conditioned by factors of the oral environment, such as periodontium soft tissue, in particular the increased gingiva or low insertion of the mucosa of the labial frenulum. These may cause patients to believe that their teeth are reduced in size, due to much more gum being exposed when they smile. The clinical case is presented of a female patient who made a dental appointment because of aesthetic dissatisfaction with her smile and dental size. After the intraoral assessment was carried out, a diagnosis was made of a localized gingivitis associated with plaque and presence of an elongated papillary frenum, giving the appearance of short or small teeth. It was decided to perform a minimally invasive surgical procedure to generate the reposition of soft tissues and improve harmony, respecting biological spaces. High-power laser therapy was performed, due to the advantages of its use, such as reduced intervention time, no requirement of local anesthesia, less bleeding, shorter healing time, and unnecessary use of sutures, compared with conventional surgery carried out with scalpel. Immediately after the procedure, the patient felt satisfaction and no pain. On day 15 post-surgery it was observed that there was no swelling of gingival tissue, reposition of the insertion of the upper frenum, and free edge of marginal gingiva in anterior-superior teeth in an apical direction.

Hiperplasia gingival fibrosa en sitio estético: enfoque quirúrgico ante recidiva / Fibrous gingival hyperplasia in esthetic zone: surgical approach on recurrence

Objetivo: aportar evidencia clínica sobre el abordaje de lesiones hiperplásicas en sitios estéticos y enfatizar la importancia de la planificación quirúrgica para reducir al mínimo su recidiva. Caso clínico: una paciente de 65 años de edad se presentó a la consulta con lesión nodular localizada en encía vestibular de pieza 21, con un período de evolución de 18 meses. Se describe el procedimiento quirúrgico inicial llevado a cabo para su tratamiento, el diagnóstico anatomopatológico, su evolución y recidiva, y un nuevo enfoque quirúrgico para su eliminación. Conclusiones: este informe enfatiza la importancia de una completa escisión de la lesión con margen de seguridad para evitar su recidiva, como objetivo primario en el abordaje quirúrgico. En sitios estéticos, la biopsia escisional, junto con la cirugía plástica periodontal, puede ser una opción para restaurar la salud gingival y devolver la estética y función al sitio

Hiperplasia gingival fibrosa en sitio estético: enfoque quirúrgico ante recidiva / Fibrous gingival hyperplasia in esthetic zone: surgical approach on recurrence

Objetivo: aportar evidencia clínica sobre el abordaje de lesiones hiperplásicas en sitios estéticos y enfatizar la importancia de la planificación quirúrgica para reducir al mínimo su recidiva. Caso clínico: una paciente de 65 años de edad se presentó a la consulta con lesión nodular localizada en encía vestibular de pieza 21, con un período de evolución de 18 meses. Se describe el procedimiento quirúrgico inicial llevado a cabo para su tratamiento, el diagnóstico anatomopatológico, su evolución y recidiva, y un nuevo enfoque quirúrgico para su eliminación. Conclusiones: este informe enfatiza la importancia de una completa escisión de la lesión con margen de seguridad para evitar su recidiva, como objetivo primario en el abordaje quirúrgico. En sitios estéticos, la biopsia escisional, junto con la cirugía plástica periodontal, puede ser una opción para restaurar la salud gingival y devolver la estética y función al sitio(AU)

Periodontal growth in areas of vascular malformation in patients with Sturge-Weber syndrome: a management protocol.

Sturge-Weber syndrome (SWS) is a very rare condition characterized by abnormal vascular formations that encompass several manifestations: cutaneous, neurologic, ocular, and oral. Neurologic conditions are the most important factor, especially epilepsy, which frequently leads patients to make use of anticonvulsants. These drugs are capable of inducing abnormal tissue growth in the oral cavity that can be situated over areas with vascular malformation, requiring special attention by the clinician. This report describes 1 case of SWS and performs a literature review of treatments for this condition, providing a protocol of treatment for these clinical situations.

Gengivectomia para o restabelecimento do arco côncavo regular: relato de caso / Gingivectomy for restoring the regular concave arch: Case report

O objetivo deste trabalho é descrever um tratamento cirúrgico periodontal na região de incisivos superiores, com a finalidade de restabelecer a estética periodontal após tratamento ortodôntico. A gengivectomia associada à plastia gengival viabilizou a estética periodontal do caso clínico apresentado, solucionando a desproporção periodontal.

The aim of this paper is to describe the surgical periodontal treatment in the maxillary incisors area for restoring periodontal esthetics after orthodontic treatment. Gengivectomy associated to gingivoplasty allowed the periodontal esthetic rehabilitation in the clinical case reported, solving the periodontal disproportion.

Hiperplasia gingival idiopática: diagnóstico y tratamiento de un caso clínico y revisión de la literatura (AU) / Idiopathic gingival hyperplasia: diagnosis and treatment of a clinical case and review of the literature

El término hiperplasia se refiere al aumento de tamaño de los tejidos en un órgano, producido por el aumento del número de sus componentes celulares. En este trabajo se presenta un caso clínico de Hiperplasia Gingival Idiopática en un paciente del sexo femenino, de 13 años de edad. El tratamiento consistió en la motivación, enseñanza de higiene bucal y terapia quirúrgica para la eliminación del tejido gingival excesivo. El estudio histopatológico confirmó el diagnóstico presuntivo. Basado en lo expuesto se analizan los diversosagrandamientos gingivales habiendo realizado una revisión del tema, según diversos autores.

Alport syndrome: significance of gingival biopsy in the initial diagnosis and periodontal evaluation after renal transplantation.

Alport Syndrome (AS) is an important hereditary disorder affecting the glomerular basement membrane. Diagnosis of AS is based on the presence of hematuric nephropathy, renal failure, hearing loss, ocular abnormalities and changes in the glomerular basement membrane of the lamina densa. The aims of this case report were to show the changes in the gingival tissues in a patient with AS under therapy with cyclosporin-A after renal transplantation and to discuss the possible role of type IV collagen in gingival basal lamina as an alternative approach for the diagnosis of AS. A 20-year-old male patient with AS underwent periodontal therapy including a series of gingivectomy surgeries. Gingival samples obtained during the second surgery were examined histopathologically and by transmission electron microscopy for further pathological examination. Gingivectomy procedures have been performed every 6 months over the last 4 years. The excessive and fibrous gingival enlargements resulted in migration of the anterior teeth, but no alveolar bone loss occurred. This is the first report to demonstrate the possible changes in the gingival tissues caused by AS. It is suggested that gingival biopsy can be an initial diagnostic tool instead of renal or skin biopsies. Proper dental and periodontal care and regular visits to the dentist could provide limited gingival hyperplasia to patients with AS.

Alport syndrome: significance of gingival biopsy in the initial diagnosis and periodontal evaluation after renal transplantation

Alport Syndrome (AS) is an important hereditary disorder affecting the glomerular basement membrane. Diagnosis of AS is based on the presence of hematuric nephropathy, renal failure, hearing loss, ocular abnormalities and changes in the glomerular basement membrane of the lamina densa. The aims of this case report were to show the changes in the gingival tissues in a patient with AS under therapy with cyclosporin-A after renal transplantation and to discuss the possible role of type IV collagen in gingival basal lamina as an alternative approach for the diagnosis of AS. A 20-year-old male patient with AS underwent periodontal therapy including a series of gingivectomy surgeries. Gingival samples obtained during the second surgery were examined histopathologically and by transmission electron microscopy for further pathological examination. Gingivectomy procedures have been performed every 6 months over the last 4 years. The excessive and fibrous gingival enlargements resulted in migration of the anterior teeth, but no alveolar bone loss occurred. This is the first report to demonstrate the possible changes in the gingival tissues caused by AS. It is suggested that gingival biopsy can be an initial diagnostic tool instead of renal or skin biopsies. Proper dental and periodontal care and regular visits to the dentist could provide limited gingival hyperplasia to patients with AS.

Tratamiento de la hiperplasia gingival en una escuela odontológica de Brasil: conceptos generales, diagnóstico y tratamiento / Treatment of gingival hyperplasia in a dental school of Brazil: general concept, diagnosis and treatment

La hiperplasia gingival es una condición patológica benigna en la que aumenta de volumen de tejido gingival de forma lenta y gradual, causando importantes molestias estéticas y funcionales en los pacientes. Se clasifica como idiopática, inflamatoria, hereditaria y asociada a drogas, según su etiología, donde cada una tiene sus peculiaridades que deben ser bien comprendidas por el cirujano-dentista, a fin de lograr el tratamiento adecuado para cada caso. Este artículo revisa la literatura reciente sobre la hiperplasia gingival, abordando su etiología y tratamiento, presentando un caso clínico de fibromatosis gingival hereditaria y su tratamiento quirúrgico.

The gingival hyperplasia is a condition in which increase in volume in benign, slow and gradual development of the gingival tissue, causing significant discomfort and aesthetic function in patients. It is classified as idiopathic, inflammatory, and hereditary drug, according to its etiology, and that each variant has its peculiarities that must be well understood by the Clinical-Dentist, in order to achieve the appropriate treatment for each case. This paper reviews the recent literature on gingival hyperplasia, addressing its etiology and treatment given, and clinical case report of hereditary gingival fibromatosis in the surgical therapy was performed successfully.

Amelogenesis imperfecta, rough hypoplastic type, dental follicular hamartomas and gingival hyperplasia: report of a case from Central America and review of the literature.

We report on a black male patient from Central America with amelogenesis imperfecta, rough hypoplastic type, dental follicular hamartomas, and gingival hyperplasia. Although previous reports have described this association of amelogenesis imperfecta with hyperplastic follicular hamartomas or central odontogenic fibroma-like lesions in blacks from South Africa, we have noticed non-black patients in the literature with similar findings.

Inflammatory fibrous hyperplasia treated with a modified vestibuloplasty: a case report.

AIM: The purpose of this report is to present a case of surgical and prosthetic treatment of a woman with inflammatory fibrous hyperplasia (IFH) and her evaluation during a six month period. BACKGROUND: IFH is a benign pathology, prevalent in female patients, and principally associated with ill-fitting prosthetic devices in need of adjustment. It is common for patients to require surgical removal of the hyperplastic tissue and fabrication of a new prosthesis. CASE REPORT: A 55-year-old female with a history of smoking presented with a chief complaint of missing the scheduled adjustment of her maxillary complete denture and the presence of moveable tissue under the denture. Surgical excision of the hyperplastic tissue followed with fixation of the prosthesis for six months to guide the healing of the soft tissue and to reshape the contours of the maxillary supporting tissues. SUMMARY: Surgical removal of hyperplasic soft tissue is a routine procedure, and the fixation of the prosthesis for the support of tissue during healing improves intraoral conditions for the fabrication of a new prosthesis in the future.

Use of the CO(2) laser on orthodontic patients suffering from gingival hyperplasia.

OBJECTIVE: The present study aimed to assess the effect of the use of the CO(2) laser on the treatment of gingival hyperplasia in orthodontic patients wearing fixed appliances. BACKGROUND DATA: Gingival hyperplasia is a condition very frequent in patients undergoing fixed orthodontic treatment. Amongst the treatments available for this is the use of surgical lasers. METHODS: Ten patients entered this study and signed an informed consent. Seventy-five anterior teeth with gingival hyperplasia were selected for laser surgery. Prior to surgery, the length of the crowns were measured using a digital caliper, and depth of the pocket was probed. The hyperplasic gingival was removed with a CO(2) laser under local anesthesia. Immediately after surgery, measurement of the length of the crowns and probing were carried out and were repeated. RESULTS: The results were statistically analyzed and significant differences were detected regarding the length of the crown (p = 0.000) and depth of the gingival sulcus (p = 0.000). CONCLUSION: It is concluded that the use of the CO(2) laser was effective in the treatment of gingival hyperplasia.

Hiperplasia gengival no paciente ortodôntico: conduta clínica / Gingival hyperplasia in the orthodontic patient: clinic conducts

Este relato de caso apresenta as condutas clínicas realizadas em paciente ortodôntico com hiperplasia gengival, história de respiração bucal e higiene bucal deficiente. O tratamento ortodôntico foi interrompido provisoriamente e foram realizados a remoção cirúrgica do excesso de tecido gengival e a aplicação tópica de clorexidina gel 1%. A integração entre Ortodontia e Periodontia mostrou eficácia com respeito à promoção de saúde e maior compatibilidade para aplicação de forças e resposta dos tecidos de suporte dentário.

Histomorphometric study of the healing of human oral mucosa after gingivoplasty and low-level laser therapy.

BACKGROUND AND OBJECTIVES: The aim of the present study was to analyze the effects of diode laser irradiation on the healing of human oral mucosa. MATERIALS AND METHODS: After gingivoplasty, the right hemi-arch (test group) of 16 patients was irradiated with a diode laser. The left side (control group) was not irradiated. Incisional biopsies were performed on both sides at 7, 14, 21, and 60 days after surgery and morphometrically analyzed by light microscopy. RESULTS: Epithelium width ranged from 260.6 to 393.5 microm. Volume densities of basal (20.2%), prickle cell (55.6%), and cornified (24.2%) layers remained stable. The peak number of neutrophils were 6 cells/mm(2) and the mononuclear cells were 44 cells/mm(2). Collagen fibers (80%) and fibroblasts (14%) occupied the main volume of connective tissue. The one-way ANOVA and the paired Student's t-test were used for statistical analysis (P < 0.05). CONCLUSION: Low-level laser therapy did not accelerate the healing of oral mucosa after gingivoplasty.

Hiperplasia gengival anatômica: relato de caso clínico / Anatomic gingival hyperplasia: a case report

A hiperplasia gengival anatômica é uma condição oral benigna que envolve desde aumento gengival ao redor da coroa dentária até deformação do palato. O presente caso clínico refere-se ao paciente A.P.D., 39 anos de idade, gênero masculino. Durante a anamnese, foi relatado que a lesão estaria presente por aproximadamente um ano, de forma assintomática, com crescimento lento e gradual. Ao exame clínico foi detectada significativa massa nodular na região posterior do palato duro, bilateral, mais proemnente no lado esquerdo. Foi realizada biópsia incisional, seguida de exame histopatológico, confirmando-se o diagnóstico clínico de hiperplasia gengival anatômica

Congenital generalized terminal hypertrichosis with gingival hyperplasia.

Congenital generalized terminal hypertrichosis is a rare disease, especially when associated with gingival hyperplasia. Congenital hypertrichosis can be a clinical feature of several syndromes, so these patients must be studied by a multidisciplinary team that should include a dermatologist, geneticist, psychologist, odontologist, and an endocrinologist. We report a 7-year-old girl with congenital generalized hypertrichosis and gingival hyperplasia, and analyze the clinical approach, differential diagnosis, and treatment.