RESUMEN
Varicella zoster virus (VZV) is the agent that causes chicken pox, a common childhood infection that characteristically presents as vesicular rashes affecting the trunk and head. After the primary infection has resolved, VZV lies dormant in the spinal dorsal root ganglia or extramedullary cranial nerve ganglia until reactivation results in herpes zoster (shingles). The sensory nerves of the trunk, as in classic shingles, and the fifth cranial nerve, as in trigeminal zoster, are the most frequently affected. Shingles is an acute viral infection characterized by the appearance of painful unilateral vesicular rash usually restricted to a dermatomal distribution of a sensory nerve. The rash of shingles is usually preceded by pain and paresthesia. A rare, severe complication of the reactivation of VZV in the geniculate ganglion of the facial nerve is Ramsay Hunt syndrome (RHS). RHS is characterized by otalgia, vesicles in the auditory canal, and ipsilateral facial paralysis. An even rarer complication of VZV infection includes post-zoster osteonecrosis. This report documents a case of severe mandibular osteonecrosis and RHS after an outbreak of herpes zoster and treatment strategies.
Asunto(s)
Herpes Zóster Ótico/virología , Enfermedades Mandibulares/virología , Osteonecrosis/virología , Antivirales/uso terapéutico , Desbridamiento/métodos , Estudios de Seguimiento , Herpes Zóster/virología , Humanos , Masculino , Enfermedades Mandibulares/cirugía , Persona de Mediana Edad , Osteonecrosis/cirugía , Tomografía Computarizada por Rayos X/métodos , Exfoliación Dental/virología , Extracción Dental/métodosRESUMEN
Ramsay Hunt syndrome (RHS) is defined as herpes zoster infection of the head and neck that involves the facial nerve. Immunocompromised people, such as those infected with human immunodeficiency virus (HIV), are predisposed to herpes zoster. However, reports of RHS in patients with HIV are rare. We report two cases of RHS in patients with HIV at our hospital, located in southern Brazil. We hope this report will increase the awareness of this condition among doctors caring for patients with HIV.
Asunto(s)
Infecciones Oportunistas Relacionadas con el SIDA/patología , VIH-1 , Herpes Zóster Ótico/patología , Infecciones Oportunistas Relacionadas con el SIDA/virología , Adulto , Brasil , Herpes Zóster Ótico/virología , Humanos , Masculino , Persona de Mediana Edad , Activación ViralAsunto(s)
Humanos , Masculino , Adulto , Herpes Zóster Ótico/diagnóstico , Parálisis Facial/diagnóstico , Aciclovir/análogos & derivados , Antivirales/uso terapéutico , Herpes Zóster Ótico/tratamiento farmacológico , Herpes Zóster Ótico/virología , /aislamiento & purificación , Reacción en Cadena de la Polimerasa , Parálisis Facial/tratamiento farmacológicoRESUMEN
Varicella-zoster virus has been associated with a variety of neurological manifestations. We describe a patient with the Ramsay Hunt Syndrome who developed a contralateral cerebral infarction.