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1.
World Neurosurg ; 157: e129-e136, 2022 01.
Artículo en Inglés | MEDLINE | ID: mdl-34619401

RESUMEN

OBJECTIVE: To develop an asleep motor mapping paradigm for accurate detection of the corticospinal tract during glioma surgery and compare outcomes with awake patients undergoing glioma resection. METHODS: A consecutive cohort of adult patients undergoing craniotomy for suspected diffuse glioma with tumor in a perirolandic location who had awake or asleep cortical and subcortical motor mapping with positive areas of motor stimulation were assessed for postoperative extent of resection (EOR), permanent neurological deficit, and proximity of stimulation to diffusion tensor imaging-based corticospinal tract depiction on preoperative magnetic resonance imaging. Outcome data were compared between asleep and awake groups. RESULTS: In the asleep group, all 16 patients had improved or no change in motor function at last follow-up (minimum 3 months of follow-up). In the awake group, all 23 patients had improved function or no change at last follow-up. EOR was greater in the asleep group (mean [SD] EOR 88.71% [17.56%]) versus the awake group (mean [SD] EOR 80.62% [24.44%]), although this difference was not statistically significant (P = 0.3802). Linear regression comparing distance from stimulation to corticospinal tract in asleep (n = 14) and awake (n = 4) patients was r = -0.3759, R2 = 0.1413, P = 0.1853, and 95% confidence interval = -0.4453 to 0.09611 and r = 0.7326, R2 = 0.5367, P = 0.2674, and 95% confidence interval = -7.042 to 14.75, respectively. CONCLUSION: In this small patient series, asleep motor mapping using commonly available motor evoked potential hardware appears to be safe and efficacious in regard to EOR and functional outcomes.


Asunto(s)
Anestesia General/métodos , Mapeo Encefálico/métodos , Encéfalo/cirugía , Sedación Consciente/métodos , Craneotomía/métodos , Vigilia/fisiología , Adulto , Anciano , Anestesia General/tendencias , Encéfalo/diagnóstico por imagen , Mapeo Encefálico/tendencias , Neoplasias Encefálicas/diagnóstico por imagen , Neoplasias Encefálicas/cirugía , Sedación Consciente/tendencias , Craneotomía/tendencias , Imagen de Difusión Tensora/métodos , Imagen de Difusión Tensora/tendencias , Potenciales Evocados Motores/fisiología , Femenino , Glioma/diagnóstico por imagen , Glioma/cirugía , Humanos , Monitorización Neurofisiológica Intraoperatoria/métodos , Monitorización Neurofisiológica Intraoperatoria/tendencias , Masculino , Persona de Mediana Edad , Adulto Joven
2.
Ann Vasc Surg ; 77: 153-163, 2021 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-34461241

RESUMEN

BACKGROUND: Hemodynamic disturbances cause half of the perioperative strokes following carotid endarterectomy (CEA). Guidelines strongly recommend strict pre- and postoperative blood pressure (BP) monitoring in CEA patients, but do not provide firm practical recommendations. Although in the Netherlands 50 centres perform CEA, no national protocol on perioperative hemodynamic, and cerebral monitoring exists. To assess current monitoring policies of all Dutch CEA-centres, a national survey was conducted. METHODS: Between May and July 2017 all 50 Dutch CEA-centres were invited to complete a 42-question survey addressing perioperative hemodynamic and cerebral monitoring during CEA. Nonresponders received a reminder after 1 and 2 months. By November 2017 the survey was completed by all centres. RESULTS: Preoperative baseline BP was based on a single bilateral BP-measurement at the outpatient-clinic in the majority of centres (n = 28). In 43 centres (86%) pre-operative monitoring (transcranial Doppler (TCD, n = 6), electroencephalography (EEG, n = 11), or TCD + EEG (n = 26)) was performed as a baseline reference. Intraoperatively, large diversity for type of anaesthesia (general: 45 vs. local [LA]:5) and target systolic BP (>100 mm hg - 160 mm hg [n = 12], based on preoperative outpatient-clinic or admission BP [n = 18], other [n = 20]) was reported. Intraoperative cerebral monitoring included EEG + TCD (n = 28), EEG alone (n = 13), clinical neurological examination with LA (n = 5), near-infrared spectroscopy with stump pressure (n = 1), and none due to standard shunting (n = 3). Postoperatively, significant variation was reported in standard duration of admission at a recovery or high-care unit (range 3-48 hr, mean:12 hr), maximum accepted systolic BP (range >100 mm hg - 180 mm Hg [n = 32]), postoperative cerebral monitoring (standard TCD [n = 16], TCD on indication [n = 5] or none [n = 24]) and in timing of postoperative cerebral monitoring (range directly postoperative - 24 hr postoperative; median 3 hr). CONCLUSIONS: In Dutch centres performing CEA the perioperative hemodynamic and cerebral monitoring policies are widely diverse. Diverse policies may theoretically lead to over- or under treatment. The results of this national audit may serve as the baseline dataset for development of a standardized and detailed (inter)national protocol on perioperative hemodynamic and cerebral monitoring during CEA.


Asunto(s)
Presión Sanguínea , Enfermedades de las Arterias Carótidas/diagnóstico , Enfermedades de las Arterias Carótidas/cirugía , Circulación Cerebrovascular , Endarterectomía Carotidea/tendencias , Monitorización Hemodinámica/tendencias , Monitorización Neurofisiológica Intraoperatoria/tendencias , Atención Perioperativa/tendencias , Pautas de la Práctica en Medicina/tendencias , Antihipertensivos/uso terapéutico , Presión Sanguínea/efectos de los fármacos , Enfermedades de las Arterias Carótidas/fisiopatología , Circulación Cerebrovascular/efectos de los fármacos , Electroencefalografía/tendencias , Endarterectomía Carotidea/efectos adversos , Encuestas de Atención de la Salud , Humanos , Auditoría Médica , Países Bajos , Valor Predictivo de las Pruebas , Espectroscopía Infrarroja Corta/tendencias , Resultado del Tratamiento
3.
World Neurosurg ; 152: e155-e160, 2021 08.
Artículo en Inglés | MEDLINE | ID: mdl-34052456

RESUMEN

BACKGROUND: Intraoperative neurophysiologic monitoring (IOM) has been used clinically since the 1970s and is a reliable tool for detecting impending neurologic compromise. However, there are mixed data as to whether long-term neurologic outcomes are improved with its use. We investigated whether IOM used in conjunction with image guidance produces different patient outcomes than with image guidance alone. METHODS: We reviewed 163 consecutive cases between January 2015 and December 2018 and compared patients undergoing posterior lumbar instrumentation with image guidance using and not using multimodal IOM. Monitored and unmonitored surgeries were performed by the same surgeons, ruling out variability in intersurgeon technique. Surgical and neurologic complication rates were compared between these 2 cohorts. RESULTS: A total of 163 patients were selected (110 in the nonmonitored cohort vs. 53 in the IOM cohort). Nineteen signal changes were noted. Only 3 of the 19 patients with signal changes had associated neurologic deficits postoperatively (positive predictive value 15.7%). There were 5 neurologic deficits that were observed in the nonmonitored cohort and 8 deficits observed in the monitored cohort. Transient neurologic deficit was significantly higher in the monitored cohort per case (P < 0.0198) and per screw (P < 0.0238); however, there was no difference observed between the 2 cohorts when considering permanent neurologic morbidity per case (P < 0.441) and per screw (P < 0.459). CONCLUSIONS: The addition of IOM to cases using image guidance does not appear to decrease long-term postoperative neurologic morbidity and may have a reduced diagnostic role given availability of intraoperative image-guidance systems.


Asunto(s)
Monitorización Neurofisiológica Intraoperatoria/métodos , Vértebras Lumbares/cirugía , Enfermedades del Sistema Nervioso/prevención & control , Complicaciones Posoperatorias/prevención & control , Fusión Vertebral/efectos adversos , Cirugía Asistida por Computador/efectos adversos , Potenciales Evocados Somatosensoriales/fisiología , Femenino , Estudios de Seguimiento , Humanos , Monitorización Neurofisiológica Intraoperatoria/tendencias , Masculino , Persona de Mediana Edad , Enfermedades del Sistema Nervioso/diagnóstico , Enfermedades del Sistema Nervioso/etiología , Complicaciones Posoperatorias/diagnóstico , Complicaciones Posoperatorias/etiología , Fusión Vertebral/tendencias , Cirugía Asistida por Computador/tendencias
4.
Neurosurg Rev ; 44(2): 867-888, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-32430559

RESUMEN

The creation of intracranial stereotactic trajectories, from entry point to target point, is still mostly done manually by the neurosurgeon. The development of automated stereotactic planning tools has been described in the literature. This systematic review aims to assess the effectiveness of stereotactic planning procedure automation and develop tools for patients undergoing neurosurgical stereotactic procedures. PubMed/MEDLINE, EMBASE, Google Scholar, CINAHL, PsycINFO, and Cochrane Register of Controlled Trials databases were searched from inception to September 1, 2019, at the exception of Google Scholar (from 1 January 2010 to September 1, 2019) in French and English. Eligible studies included all studies proposing automated stereotactic planning. A total of 1543 studies were screened. Forty-two studies were included in the systematic review, including 18 (42.9%) conference papers. The surgical procedures planned automatically were mainly deep brain stimulation (n = 14, 33.3%), stereoelectroencephalography (n = 12, 28.6%), and not specified (n = 10, 23.8%). The most frequently used surgical constraints to plan the trajectory were blood vessels (n = 32, 76.2%), cerebral sulci (n = 27, 64.3%), and cerebral ventricles (n = 23, 54.8%). The distance from blood vessels ranged from 1.96 to 4.78 mm for manual trajectories and from 2.47 to 7.0 mm for automated trajectories. At least one neurosurgeon was involved in 36 studies (85.7%). The automated stereotactic trajectory was preferred in 75.4% of the studied cases (range 30-92.9). Only 3 (7.1%) studies were multicentric. No study reported prospective use of the planning software. Stereotactic planning automation is a promising tool to provide valuable stereotactic trajectories for clinical applications.


Asunto(s)
Monitorización Neurofisiológica Intraoperatoria/métodos , Procedimientos Neuroquirúrgicos/métodos , Ensayos Clínicos Controlados Aleatorios como Asunto/métodos , Técnicas Estereotáxicas , Cirugía Asistida por Computador/métodos , Adulto , Electrodos Implantados , Femenino , Humanos , Imagenología Tridimensional/métodos , Imagenología Tridimensional/tendencias , Monitorización Neurofisiológica Intraoperatoria/tendencias , Masculino , Persona de Mediana Edad , Procedimientos Neuroquirúrgicos/tendencias , Estudios Prospectivos , Técnicas Estereotáxicas/tendencias , Cirugía Asistida por Computador/tendencias
5.
World Neurosurg ; 145: 574-580, 2021 01.
Artículo en Inglés | MEDLINE | ID: mdl-33348523

RESUMEN

Magnetic resonance-guided focused ultrasound is a powerful new technology that is enabling development of noninvasive applications for complex brain disorders. This is currently revolutionizing the treatment of tremor disorders, and a variety of experimental applications are under active investigation. To fully realize the potential of this disruptive technology, many challenges have been identified, some of which have been addressed and others remain to be solved. As an image-based technology, optimal intraoperative imaging can be difficult to achieve and several factors can influence the quality of these images. Technical issues with current devices can also limit the effective delivery of ultrasound technology to particular targets. While lesioning is the primary approved application of magnetic resonance-guided focused ultrasound at present, the ability to transient and precisely open the blood-brain barrier has the potential to clear brain pathologies and deliver restorative therapies, but this more experimental method presents unique difficulties to overcome. Finally, regulatory and reimbursement hurdles currently remain complex and continue to limit widespread application of even approved, effective applications. Here we review many of these challenges, discuss several solutions that have already been developed, and propose potential options for addressing some of these complexities in the future.


Asunto(s)
Encefalopatías/diagnóstico por imagen , Encefalopatías/cirugía , Ultrasonido Enfocado de Alta Intensidad de Ablación/métodos , Monitorización Neurofisiológica Intraoperatoria/métodos , Imagen por Resonancia Magnética/métodos , Barrera Hematoencefálica/diagnóstico por imagen , Barrera Hematoencefálica/cirugía , Temblor Esencial/diagnóstico por imagen , Temblor Esencial/cirugía , Predicción , Ultrasonido Enfocado de Alta Intensidad de Ablación/tendencias , Humanos , Monitorización Neurofisiológica Intraoperatoria/tendencias , Imagen por Resonancia Magnética/tendencias , Enfermedad de Parkinson/diagnóstico por imagen , Enfermedad de Parkinson/cirugía , Cráneo/diagnóstico por imagen , Cráneo/cirugía
6.
Brain Stimul ; 13(6): 1765-1773, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33035725

RESUMEN

BACKGROUND: Deep Brain Stimulation (DBS) targeting the subthalamic nucleus (STN) and globus pallidus interna (GPi) is an effective treatment for cardinal motor symptoms and motor complications in Parkinson's Disease (PD). However, malpositioned DBS electrodes can result in suboptimal therapeutic response. OBJECTIVE: We explored whether recovery of the H-reflex-an easily measured electrophysiological analogue of the stretch reflex, known to be altered in PD-could serve as an adjunct biomarker of suboptimal versus optimal electrode position during STN- or GPi-DBS implantation. METHODS: Changes in soleus H-reflex recovery were investigated intraoperatively throughout awake DBS target refinement across 26 nuclei (14 STN). H-reflex recovery was evaluated during microelectrode recording (MER) and macrostimulation at multiple locations within and outside target nuclei, at varying stimulus intensities. RESULTS: Following MER, H-reflex recovery normalized (i.e., became less Parkinsonian) in 21/26 nuclei, and correlated with on-table motor improvement consistent with an insertional effect. During macrostimulation, H-reflex recovery was maximally normalized in 23/26 nuclei when current was applied at the location within the nucleus producing optimal motor benefit. At these optimal sites, H-reflex normalization was greatest at stimulation intensities generating maximum motor benefit free of stimulation-induced side effects, with subthreshold or suprathreshold intensities generating less dramatic normalization. CONCLUSION: H-reflex recovery is modulated by stimulation of the STN or GPi in patients with PD and varies depending on the location and intensity of stimulation within the target nucleus. H-reflex recovery shows potential as an easily-measured, objective, patient-specific, adjunct biomarker of suboptimal versus optimal electrode position during DBS surgery for PD.


Asunto(s)
Estimulación Encefálica Profunda/métodos , Electrodos Implantados , Reflejo H/fisiología , Monitorización Neurofisiológica Intraoperatoria/métodos , Enfermedad de Parkinson/terapia , Adulto , Anciano , Biomarcadores , Estimulación Encefálica Profunda/tendencias , Electrodos Implantados/tendencias , Femenino , Globo Pálido/fisiología , Humanos , Monitorización Neurofisiológica Intraoperatoria/tendencias , Masculino , Microelectrodos/tendencias , Persona de Mediana Edad , Enfermedad de Parkinson/fisiopatología , Núcleo Subtalámico/fisiología , Resultado del Tratamiento , Vigilia/fisiología
7.
Neurosurg Focus ; 48(6): E14, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-32480376

RESUMEN

OBJECTIVE: Many innovations have been introduced into pituitary surgery in the quest to maximize the extent of tumor resection. Because of the deep and narrow surgical corridor as well as the heterogeneity of confronted pathologies, anatomical orientation and identification of the target tissue can become difficult. Intraoperative MRI (iMRI) may have the potential to increase extent of resection (EOR) in transsphenoidal pituitary surgery. Furthermore, it may simplify anatomical orientation and risk assessment in difficult cases. Here, the authors evaluated the additional value of iMRI for the resection of pituitary adenomas performed in the past 10 years in their department. METHODS: They performed a retrospective single-center analysis of patients treated for pituitary adenoma in their department after the introduction of iMRI between 2008 and 2018. Of 495 transsphenoidal approaches, 300 consecutive MRI-assisted surgeries for pituitary adenomas encompassing 294 patients were selected for further analysis. Microscopic, endoscopic, or endoscope-assisted microscopic transsphenoidal approaches were distinguished. EOR as well as additional resection following iMRI was evaluated via detailed volumetric analysis. Patients were stratified according to the Knosp adenoma classification. Furthermore, demographic data, clinical symptoms, endocrine outcome, and complications were evaluated. Univariable and multivariable Cox regression analyses of progression-free survival (PFS) were performed. RESULTS: Pituitary adenomas classified as Knosp grades 0-2 were found in 60.3% of cases (n = 181). The most common tumors were nonfunctioning adenomas (75%). Continued resection following iMRI significantly increased EOR (7.5%, p < 0.001) and the proportion of gross-total resections (GTRs) in transsphenoidal pituitary surgery (54% vs 68.3%, p < 0.001). Additional resection after iMRI was performed in 37% of cases. Only in the subgroup of patients with Knosp grades 0-2 adenomas treated with the microsurgical technique was additional resection significantly more common than in the endoscopic group (p = 0.039). Residual tumor volume, Knosp grade, and age were confirmed as independent predictors of PFS (p < 0.001, p = 0.021, and p = 0.029, respectively) in a multivariable Cox regression analysis. Improvement of visual field deficits was documented in 78.6% of patients whose optic apparatus had been affected preoperatively. Revision surgery was done in 7.3% of cases; in 5.6% of cases, it was performed for cerebrospinal fluid fistula. CONCLUSIONS: In this series, iMRI led to the detection of a resectable tumor remnant in a high proportion of patients, resulting in a greater EOR and higher proportion of GTRs after continued resection in microsurgical and endoscopic transsphenoidal resection of pituitary adenomas. The volume of residual tumor was the most important predictor of PFS. Given the study data, the authors postulated that every bit of removed tumor serves the patient and increases their chances of a favorable outcome.


Asunto(s)
Adenoma/cirugía , Monitorización Neurofisiológica Intraoperatoria/tendencias , Imagen por Resonancia Magnética/tendencias , Neuroendoscopía/tendencias , Neoplasias Hipofisarias/cirugía , Hueso Esfenoides/cirugía , Adenoma/diagnóstico por imagen , Adulto , Anciano , Femenino , Estudios de Seguimiento , Humanos , Monitorización Neurofisiológica Intraoperatoria/métodos , Imagen por Resonancia Magnética/métodos , Masculino , Persona de Mediana Edad , Neuroendoscopía/métodos , Neoplasias Hipofisarias/diagnóstico por imagen , Estudios Retrospectivos , Hueso Esfenoides/diagnóstico por imagen , Factores de Tiempo , Resultado del Tratamiento , Carga Tumoral/fisiología
8.
World Neurosurg ; 140: 664-673, 2020 08.
Artículo en Inglés | MEDLINE | ID: mdl-32445895

RESUMEN

BACKGROUND: The desire to improve accuracy and safety and to favor minimally invasive techniques has given rise to spinal robotic surgery, which has seen a steady increase in utilization in the past 2 decades. However, spinal surgery encompasses a large spectrum of operative techniques, and robotic surgery currently remains confined to assistance with the trajectory of pedicle screw insertion, which has been shown to be accurate and safe based on class II and III evidence. The role of robotics in improving surgical outcomes in spinal pathologies is less clear, however. METHODS: This comprehensive review of the literature addresses the role of robotics in surgical outcomes in spinal pathologies with a focus on the various meta-analysis and prospective randomized trials published within the past 10 years in the field. RESULTS: It appears that robotic spinal surgery might be useful for increasing accuracy and safety in spinal instrumentation and allows for a reduction in surgical time and radiation exposure for the patient, medical staff, and operator. CONCLUSION: Robotic assisted surgery may thus open the door to minimally invasive surgery with greater security and confidence. In addition, the use of robotics facilitates tireless repeated movements with higher precision compared with humans. Nevertheless, it is clear that further studies are now necessary to demonstrate the role of this modern tool in cost-effectiveness and in improving clinical outcomes, such as reoperation rates for screw malpositioning.


Asunto(s)
Procedimientos Quirúrgicos Robotizados/instrumentación , Procedimientos Quirúrgicos Robotizados/tendencias , Enfermedades de la Columna Vertebral/cirugía , Cirugía Asistida por Computador/instrumentación , Cirugía Asistida por Computador/tendencias , Fluoroscopía/instrumentación , Fluoroscopía/tendencias , Humanos , Monitorización Neurofisiológica Intraoperatoria/instrumentación , Monitorización Neurofisiológica Intraoperatoria/tendencias , Procedimientos Quirúrgicos Mínimamente Invasivos/instrumentación , Procedimientos Quirúrgicos Mínimamente Invasivos/tendencias , Ensayos Clínicos Controlados Aleatorios como Asunto/métodos , Enfermedades de la Columna Vertebral/diagnóstico por imagen , Resultado del Tratamiento
10.
Stereotact Funct Neurosurg ; 97(3): 141-152, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31412334

RESUMEN

The last two decades have seen a re-emergence of surgery for intractable psychiatric disease, in large part due to increased use of deep brain stimulation. The development of more precise, image-guided, less invasive interventions has improved the safety of these procedures, even though the relative merits of modulation at various targets remain under investigation. With an increase in the number and type of interventions for modulating mood/anxiety circuits, the need for biomarkers to guide surgeries and predict treatment response is as critical as ever. Electroencephalography (EEG) has a long history in clinical neurology, cognitive neuroscience, and functional neurosurgery, but has limited prior usage in psychiatric surgery. MEDLINE, Embase, and Psyc-INFO searches on the use of EEG in guiding psychiatric surgery yielded 611 articles, which were screened for relevance and quality. We synthesized three important themes. First, considerable evidence supports EEG as a biomarker for response to various surgical and non-surgical therapies, but large-scale investigations are lacking. Second, intraoperative EEG is likely more valuable than surface EEG for guiding target selection, but comes at the cost of greater invasiveness. Finally, EEG may be a promising tool for objective functional feedback in developing "closed-loop" psychosurgeries, but more systematic investigations are required.


Asunto(s)
Electroencefalografía/métodos , Monitorización Neurofisiológica Intraoperatoria/métodos , Trastornos Mentales/cirugía , Psicocirugía/métodos , Estimulación Encefálica Profunda/métodos , Estimulación Encefálica Profunda/tendencias , Electroencefalografía/tendencias , Predicción , Humanos , Monitorización Neurofisiológica Intraoperatoria/tendencias , Trastornos Mentales/diagnóstico , Trastornos Mentales/psicología , Procedimientos Neuroquirúrgicos/métodos , Procedimientos Neuroquirúrgicos/tendencias , Psicocirugía/tendencias
11.
Childs Nerv Syst ; 35(10): 1769-1776, 2019 10.
Artículo en Inglés | MEDLINE | ID: mdl-31346737

RESUMEN

INTRODUCTION: The role of intraoperative neurophysiological monitoring (IONM) during surgery for Chiari I malformation has not been fully elucidated. Questions remain regarding its utility as an adjunct to foramen magnum decompression surgery, specifically, does IONM improve the safety profile of foramen magnum decompression surgery and can IONM parameters help in intraoperative surgical decision-making. This study aimed to describe a single institution experience of IOM during paediatric Chiari I surgery. METHODS: The methodology comprised a retrospective review of prospectively collected electronic neurosurgical departmental operative database. Inclusion criteria were children under 16 years of age who had undergone foramen magnum decompression for Chiari I malformation with IONM. In addition to basic demographic data, details pertaining to presenting features and post-operative outcomes were obtained. These included primary symptoms of Chiari I malformation and indications for surgery. MRI findings, including the presence of syringomyelia on pre-and post-operative imaging, were reviewed. Details of the surgical technique for each patient were recorded. Only patients with either serial brainstem auditory evoked potential (BAEP) and/or upper limb somatosensory evoked potential (SSEP) recordings were included. Two time points were used for the purposes of analysing IONM data; initial baseline before skin incision and final at the time of skin closure. RESULTS: Thirty-seven children underwent foramen magnum decompression (FMD) with IONM. Mean age was 10.5 years (range 1-16 years) with a male:female ratio 13:24. The commonest clinical features on presentation included headaches (15) and scoliosis (13). Twenty-four patients had evidence of associated syringomyelia (24/37 = 64.9%). A reduction in the SSEP latency was observed in all patients. SSEP amplitude was more variable, with a decrease seen in 18 patients and an increase observed in 12 patients. BAEP recordings decreased in 13 patients and increased in 4 patients. There were no adverse neurological events following surgery; the primary symptom was resolved or improved in all patients at 3-month follow-up. Resolution or improvement in syringomyelia was observed in 19/24 cases. CONCLUSIONS: Our data shows that FMD for Chiari malformation (CM) is associated with changes in SSEPs and BAEPs. However, we did not identify a definite link between clinical outcomes and IONM, nor did syrinx outcome correlate with IONM. There may be a role for IONM in CM surgery but more robust data with better-defined parameters are required to further understand the impact of IONM in CM surgery.


Asunto(s)
Malformación de Arnold-Chiari/fisiopatología , Malformación de Arnold-Chiari/cirugía , Potenciales Evocados Auditivos/fisiología , Potenciales Evocados Somatosensoriales/fisiología , Monitorización Neurofisiológica Intraoperatoria/métodos , Adolescente , Malformación de Arnold-Chiari/diagnóstico , Niño , Preescolar , Femenino , Humanos , Lactante , Monitorización Neurofisiológica Intraoperatoria/tendencias , Masculino , Estudios Prospectivos , Estudios Retrospectivos
12.
Acta Neurochir (Wien) ; 161(9): 1865-1875, 2019 09.
Artículo en Inglés | MEDLINE | ID: mdl-31227966

RESUMEN

BACKGROUND: Intraoperative neurophysiological monitoring is widely used in spine surgery (sIONM). But guidelines are lacking and its use is mainly driven by individual surgeons' preferences and medicolegal advisements. To gain an overview over the current status of sIONM implementation, we conducted a transnational survey in the German-speaking countries. METHODS: We developed a Web interface-based survey assessing prevalence, indication, technical implementation, and general satisfaction regarding sIONM in German, Austrian, and Swiss spine centers. The electronic survey was performed between November 2017 and April 2018, including both neurosurgical and orthopedic spine centers. RESULTS: A total of 463 German, 60 Austrian, and 52 Swiss spine centers were contacted with participation rates of 64.1% (Germany), 68.3% (Austria), and 55.8% (Switzerland). Some 75.9% participating neurosurgical spine centers and only 14.7% of the orthopedic spine centers applied sIONM. Motor- and somatosensory-evoked potentials (93.7% and 94.3%, respectively) were the most widely available modalities, followed by direct wave (D wave; 66.5%). Whereas sIONM utilization was low in spine surgeries for degenerative, traumatic, and extradural tumor diseases, it was high for scoliosis and intradural tumor surgeries. Overall, the general satisfaction within the institutional setting regarding technical skills, staff, performance, and reliability of sIONM was rated as "high" by more than three-quarters of the centers. However, shortage of skilled staff was claimed to be a negative factor by 41.1% of the centers and reimbursement was considered to be insufficient by 83.5%. CONCLUSIONS: sIONM availability was high in neurosurgical but low in orthopedic spine centers. Main modalities were motor/somatosensory-evoked potentials and main indications were scoliosis and intradural spinal tumor surgeries. A more frequent sIONM use, however, was mainly limited by the shortage of skilled staff and restricted reimbursement.


Asunto(s)
Monitorización Neurofisiológica Intraoperatoria/tendencias , Procedimientos Neuroquirúrgicos/métodos , Procedimientos Ortopédicos/métodos , Columna Vertebral/cirugía , Austria , Potenciales Evocados Motores , Potenciales Evocados Somatosensoriales , Alemania , Humanos , Procedimientos Neuroquirúrgicos/estadística & datos numéricos , Procedimientos Ortopédicos/estadística & datos numéricos , Escoliosis/cirugía , Neoplasias de la Médula Espinal/cirugía , Enfermedades de la Columna Vertebral/cirugía , Traumatismos Vertebrales/cirugía , Neoplasias de la Columna Vertebral/cirugía , Cirujanos , Encuestas y Cuestionarios , Suiza
13.
Childs Nerv Syst ; 35(10): 1905-1909, 2019 10.
Artículo en Inglés | MEDLINE | ID: mdl-31073684

RESUMEN

PURPOSE: Describe presentation and management of Chiari type 1 malformation. We report our surgical case series proposing a decision making scheme for helping surgeons decide which surgical procedure to perform and when. METHODS: We retrospectively examined a series of surgically treated patients with Chiari type 1 malformation. Treatment of associated anomalies, surgical complications, and need for reintervention for insufficient decompression at first surgery are discussed. RESULTS: A total of 172 patients have been surgically treated for Chiari type 1 malformation at the Neurosurgery Unit of IRCCS Giannina Gaslini Children Hospital of Genoa, Italy, in a period between 2006 and 2017. The first treatment addressing Chiari type 1 malformation was bone and ligamentous decompression alone in 104 patients (65%), associated with dural delamination in 3 patients (1.9%) and associated with duraplasty with autologous graft in 53 patients (33.1%). Postoperative complications occurred in 5 patients (2.9%). Reintervention for insufficient decompression at follow-up was needed in 6 patients (3.5%). CONCLUSIONS: Surgical decompression of the posterior cranial fossa (PCF) is indicated in symptomatic patients while asymptomatic patients must be followed in a wait and see fashion. Different types of surgical decompression of different invasiveness have been proposed from only bone and ligamentous decompression to coagulation of cerebellar tonsils. Intraoperative ultrasonography is a useful tool to define when a decompression is sufficient. We did not find correlation between the need for reintervention for insufficient decompression and different invasiveness of the techniques. We believe that this finding suggests that our proposed scheme leads to the best tailored treatment for the single patient.


Asunto(s)
Malformación de Arnold-Chiari/cirugía , Descompresión Quirúrgica/tendencias , Manejo de la Enfermedad , Monitorización Neurofisiológica Intraoperatoria/tendencias , Adolescente , Malformación de Arnold-Chiari/diagnóstico por imagen , Malformación de Arnold-Chiari/epidemiología , Niño , Preescolar , Femenino , Estudios de Seguimiento , Humanos , Lactante , Italia/epidemiología , Masculino , Complicaciones Posoperatorias/diagnóstico por imagen , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/prevención & control , Estudios Retrospectivos , Resultado del Tratamiento , Adulto Joven
14.
Brain Stimul ; 12(4): 893-900, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-30876883

RESUMEN

BACKGROUND: Deep brain stimulation (DBS) is a well-established surgical therapy for Parkinson's disease (PD). Intraoperative imaging (IMG), intraoperative physiology (PHY) and their combination (COMB) are the three mainstream DBS guidance methods. OBJECTIVE: To comprehensively compare the use of IMG-DBS, PHY-DBS and COMB-DBS in treating PD. METHODS: PubMed, Embase, the Cochrane Library and OpenGrey were searched to identify PD-DBS studies reporting guidance techniques published between January 1, 2010, and May 1, 2018. We quantitatively compared the therapeutic effects, surgical time, target error and complication risk and qualitatively compared the patient experience, cost and technical prospects. A meta-regression analysis was also performed. This study is registered with PROSPERO, number CRD42018105995. RESULTS: Fifty-nine cohorts were included in the main analysis. The three groups were equivalent in therapeutic effects and infection risks. IMG-DBS (p < 0.001) and COMB-DBS (p < 0.001) had a smaller target error than PHY-DBS. IMG-DBS had a shorter surgical time (p < 0.001 and p = 0.008, respectively) and a lower intracerebral hemorrhage (ICH) risk (p = 0.013 and p = 0.004, respectively) than PHY- and COMB-DBS. The use of intraoperative imaging and microelectrode recording correlated with a higher surgical accuracy (p = 0.018) and a higher risk of ICH (p = 0.049). CONCLUSIONS: The comparison of COMB-DBS and PHY-DBS showed intraoperative imaging's superiority (higher surgical accuracy), while the comparison of COMB-DBS and IMG-DBS showed physiological confirmation's inferiority (longer surgical time and higher ICH risk). Combined with previous evidence, the use of intraoperative neuroimaging techniques should become a future trend.


Asunto(s)
Estimulación Encefálica Profunda/métodos , Monitorización Neurofisiológica Intraoperatoria/métodos , Enfermedad de Parkinson/diagnóstico por imagen , Enfermedad de Parkinson/terapia , Vigilia/fisiología , Estimulación Encefálica Profunda/tendencias , Femenino , Humanos , Monitorización Neurofisiológica Intraoperatoria/tendencias , Microelectrodos , Estudios Observacionales como Asunto/métodos , Enfermedad de Parkinson/fisiopatología , Resultado del Tratamiento
15.
J Neurointerv Surg ; 11(2): 127-132, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-29930159

RESUMEN

BACKGROUND: Stent retriever thrombectomy (SRT) in acute thromboembolic stroke can result in post-thrombectomy subarachnoid hemorrhage (PTSAH). Intraprocedural findings associated with PTSAH are not well defined. OBJECTIVE: To identify angiographic findings and procedural factors during SRT that are associated with PTSAH. MATERIALS AND METHODS: This was a retrospective, observational cohort study of consecutive patients with middle cerebral artery (MCA) acute ischemic stroke treated with SRT. Inclusion criteria were: (1) age ≥18 years; (2) thromboembolic occlusion of the MCA; (3) at least one stent retriever pass beginning in an M2 branch; (4) postprocedural CT or MRI scan within 24 hours; (5) non-enhanced CT Alberta Stroke Program Early CT Score >5. Exclusion criteria included multi-territory stroke before SRT. RESULTS: Eighty-five patients were enrolled; eight patients had PTSAH (group 1) and 77 did not (group 2). Baseline demographic and clinical characteristics were comparable between the two groups. In group 1, a significantly greater proportion of patients had more than two stent retriever passes (62.5% vs 18.2%, P=0.01), a stent retriever positioned ≥2 cm along an M2 branch (100% vs 30.2%, P=0.002), and the presence of severe iatrogenic vasospasm before SRT pass (37.5% vs 5.2%, P=0.02). One patient with PTSAH and associated mass effect deteriorated clinically. CONCLUSIONS: An increased number of stent retriever passes, distal device positioning, and presence of severe vasospasm were associated with PTSAH. Neurological deterioration with PTSAH can occur.


Asunto(s)
Infarto de la Arteria Cerebral Media/diagnóstico por imagen , Monitorización Neurofisiológica Intraoperatoria/métodos , Stents , Accidente Cerebrovascular/diagnóstico por imagen , Hemorragia Subaracnoidea/diagnóstico por imagen , Trombectomía/efectos adversos , Adolescente , Adulto , Anciano , Estudios de Cohortes , Femenino , Humanos , Infarto de la Arteria Cerebral Media/cirugía , Monitorización Neurofisiológica Intraoperatoria/tendencias , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Estudios Prospectivos , Estudios Retrospectivos , Accidente Cerebrovascular/cirugía , Hemorragia Subaracnoidea/etiología , Trombectomía/tendencias , Adulto Joven
19.
Rev. neurol. (Ed. impr.) ; 66(9): 315-320, 1 mayo, 2018. tab, graf
Artículo en Español | IBECS | ID: ibc-173325

RESUMEN

La monitorización neurofisiológica intraoperatoria (MNIO) es hoy en día una herramienta más dentro del quirófano que busca evitar secuelas neurológicas derivadas del acto quirúrgico. Nuestro objetivo, desde la Asociación de Monitorización Intraquirúrgica Neurofisiológica Española (AMINE), en colaboración con la Sociedad Española de Neurofisiología Clínica (SENFC) y el Grupo de Trabajo de MNIO de la SENFC, ha sido recopilar datos para conocer la situación actual de la MNIO en España por hospitales, comunidades autónomas y ciudades autónomas de Ceuta y Melilla, las opiniones de los especialistas en neurofisiología clínica involucrados en este tema y las perspectivas de futuro. La recopilación de los datos se ha realizado durante el período de noviembre de 2015 a mayo de 2016 mediante contacto telefónico o correo electrónico con especialistas de neurofisiología clínica del Sistema Nacional de Salud, y mediante una encuesta vía informática en la que también participaron algunos centros sanitarios privados. Con los datos obtenidos consideramos desde la perspectiva de la AMINE y la SENFC que el campo de la medicina que abarca la MNIO en estos momentos es muy amplio y seguirá creciendo. Por eso, se precisa un mayor número de especialistas en neurofisiología clínica, así como una mayor formación específica dentro de la especialidad, que implica incrementar el período formativo actual de los médicos internos residentes en función a competencias debido al incremento de las técnicas/procedimientos, así como su complejidad


Intraoperative neurophysiological monitoring (IONM) is nowadays another tool within the operating room that seeks to avoid neurological sequels derived from the surgical act. The Spanish Neurophysiological Intra-Surgical Monitoring Association (AMINE) in collaboration with the Spanish Society of Clinical Neurophysiology (SENFC), and the IONM Working Group of the SENFC has been collecting data in order to know the current situation of the IONM in Spain by hospitals, autonomous communities including the autonomous cities of Ceuta and Melilla, the opinions of the specialists in clinical neurophysiology involved in this topic and further forecasts regarding IONM. The data was gathered from November 2015 to May 2016 through telephone contact and/or email with specialists in clinical neurophysiology of the public National Health System, and through a computerized survey that also includes private healthcare centers. With the data obtained, from the perspective of AMINE and the SENFC we consider that nowadays the field of medicine covered by IONM is considerably large and it is foreseen that it will continue to grow. Therefore, a greater number of specialists in Clinical Neurophysiology will be required, as well as the need for specific training within the specialty that involves increasing the training period of MIRs based on competencies due to the increase in techniques/procedures, as well as its complexity


Asunto(s)
Humanos , Neurofisiología/tendencias , Monitorización Neurofisiológica Intraoperatoria/métodos , Monitorización Neurofisiológica Intraoperatoria/tendencias , España/epidemiología , Telemedicina/tendencias , Encuestas y Cuestionarios
20.
Rev Neurol ; 66(9): 315-320, 2018 May 01.
Artículo en Español | MEDLINE | ID: mdl-29696619

RESUMEN

Intraoperative neurophysiological monitoring (IONM) is nowadays another tool within the operating room that seeks to avoid neurological sequels derived from the surgical act. The Spanish Neurophysiological Intra-Surgical Monitoring Association (AMINE) in collaboration with the Spanish Society of Clinical Neurophysiology (SENFC), and the IONM Working Group of the SENFC has been collecting data in order to know the current situation of the IONM in Spain by hospitals, autonomous communities including the autonomous cities of Ceuta and Melilla, the opinions of the specialists in clinical neurophysiology involved in this topic and further forecasts regarding IONM. The data was gathered from November 2015 to May 2016 through telephone contact and/or email with specialists in clinical neurophysiology of the public National Health System, and through a computerized survey that also includes private healthcare centers. With the data obtained, from the perspective of AMINE and the SENFC we consider that nowadays the field of medicine covered by IONM is considerably large and it is foreseen that it will continue to grow. Therefore, a greater number of specialists in Clinical Neurophysiology will be required, as well as the need for specific training within the specialty that involves increasing the training period of MIRs based on competencies due to the increase in techniques/procedures, as well as its complexity.


TITLE: Monitorizacion neurofisiologica intraoperatoria en España: inicios, situacion actual y perspectivas de futuro.La monitorizacion neurofisiologica intraoperatoria (MNIO) es hoy en dia una herramienta mas dentro del quirofano que busca evitar secuelas neurologicas derivadas del acto quirurgico. Nuestro objetivo, desde la Asociacion de Monitorizacion Intraquirurgica Neurofisiologica Española (AMINE), en colaboracion con la Sociedad Española de Neurofisiologia Clinica (SENFC) y el Grupo de Trabajo de MNIO de la SENFC, ha sido recopilar datos para conocer la situacion actual de la MNIO en España por hospitales, comunidades autonomas y ciudades autonomas de Ceuta y Melilla, las opiniones de los especialistas en neurofisiologia clinica involucrados en este tema y las perspectivas de futuro. La recopilacion de los datos se ha realizado durante el periodo de noviembre de 2015 a mayo de 2016 mediante contacto telefonico o correo electronico con especialistas de neurofisiologia clinica del Sistema Nacional de Salud, y mediante una encuesta via informatica en la que tambien participaron algunos centros sanitarios privados. Con los datos obtenidos consideramos desde la perspectiva de la AMINE y la SENFC que el campo de la medicina que abarca la MNIO en estos momentos es muy amplio y seguira creciendo. Por eso, se precisa un mayor numero de especialistas en neurofisiologia clinica, asi como una mayor formacion especifica dentro de la especialidad, que implica incrementar el periodo formativo actual de los medicos internos residentes en funcion a competencias debido al incremento de las tecnicas/procedimientos, asi como su complejidad.


Asunto(s)
Monitorización Neurofisiológica Intraoperatoria/tendencias , Grupos Diagnósticos Relacionados , Predicción , Historia del Siglo XX , Historia del Siglo XXI , Hospitales Privados/estadística & datos numéricos , Hospitales Públicos/estadística & datos numéricos , Humanos , Monitorización Neurofisiológica Intraoperatoria/historia , Neurofisiología/educación , Guías de Práctica Clínica como Asunto , Utilización de Procedimientos y Técnicas , Sociedades Médicas , España , Encuestas y Cuestionarios
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