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1.
Cient. dent. (Ed. impr.) ; 18(1): 21-28, feb. 2021. ilus
Artículo en Español | IBECS | ID: ibc-201767

RESUMEN

Cada día con más frecuencia en las clínicas odontológicas nos enfrentamos a atrofias maxilares y mandibulares más extremas y en muchos casos con el retratamiento de implantes fracasados biológica y/o mecánicamente. En el presente caso clínico mostramos una paciente con una atrofia combinada (horizontal y verticalmente) además de un tratamiento con implantes dentales fracasado


More and more frequently in dental clinics we are confronted with more extreme maxillary and mandibular atrophy and in many cases with the retreatment of biologically and/or mechanically failed implants. In the present clinical case we show a patient with a combined atrophy (horizontally and vertically) in addition to a failed dental implant treatment


Asunto(s)
Humanos , Femenino , Anciano , Anomalías Maxilomandibulares/diagnóstico por imagen , Periimplantitis/diagnóstico por imagen , Implantación Dental Endoósea/métodos , Pérdida de Hueso Alveolar/complicaciones , Ortodoncia Correctiva/métodos , Fracaso de la Restauración Dental , Anomalías Maxilomandibulares/terapia , Boca Edéntula/rehabilitación
2.
J Craniofac Surg ; 31(4): e391-e393, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-32168129

RESUMEN

Syngnathia is a rare facial anomaly associated with neonatal problems, including a compromised airway, and the inability to take in solids and/or liquids. Syngnathia is included within the spectrum of oromandibular limb hypogenesis syndrome, an extremely rare condition characterized by varying degrees of congenital malformation involving the tongue, mandible, and limbs. In this report, we describe the case of a 41-day-old Caucasian female infant who was unable to open her mouth beginning at birth. The authors performed osteotomies to separate fused bone, and placed a bite block at the osteotomy sites to prevent bone fusion recurrence. At 2 years of follow-up patient remained with 14 mm of mouth opening.


Asunto(s)
Anomalías Maxilomandibulares/diagnóstico por imagen , Anomalías de la Boca/diagnóstico por imagen , Anomalías Múltiples , Femenino , Humanos , Lactante , Anomalías Maxilomandibulares/cirugía , Mandíbula/anomalías , Anomalías de la Boca/cirugía , Osteotomía , Lengua/anomalías
3.
J Craniofac Surg ; 31(3): e245-e247, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31934975

RESUMEN

Many methods have been devised to repair cranial defects. Here, we report the use of a simple technique for the repair of a congenital cranial defect associated with aplasia cutis congenita (ACC).A newborn baby at 39 weeks of gestation was consulted with a scalp and cranial defect at the vertex measuring 3 × 1.5 cm. A 3-D CT scan of the skull confirmed the presence of a cranial defect at the sagittal suture and a normal brain structure. On the 13 day of life, the newborn was taken to an operating room. An autologous bone graft was harvested from adjacent normal parietal bone and grafted into the debrided congenital cranial defect. The soft tissue defect was then covered by rotation flaps.The postoperative 3-D CT scan presented a well-positioned autologous bone graft. At 1 month postoperatively, the skull contour was normal and there was no palpable defect.We report a successful surgical outcome for a congenital cranial and soft tissue defect in ACC treated using an autologous bone graft and rotation flaps. Although conservative therapy may be an alternative option, we recommend appropriate surgical reconstruction in patients at risk of potentially fatal complications.


Asunto(s)
Trasplante Óseo , Displasia Ectodérmica/cirugía , Anomalías Maxilomandibulares/cirugía , Suturas Craneales , Displasia Ectodérmica/diagnóstico por imagen , Humanos , Recién Nacido , Anomalías Maxilomandibulares/diagnóstico por imagen , Hueso Parietal/anomalías , Hueso Parietal/diagnóstico por imagen , Hueso Parietal/cirugía , Cuero Cabelludo/cirugía , Colgajos Quirúrgicos , Tomografía Computarizada por Rayos X , Trasplante Autólogo
4.
J Craniofac Surg ; 31(3): 692-696, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31977684

RESUMEN

Unicoronal craniosynostosis is the second most common type of nonsyndromic craniosynostosis: it is characterized by ipsilateral forehead and fronto-parietal region flattening with contralateral compensatory bossing. It is a complex condition; therefore, which is difficult to treat because of the asymmetry in the orbits, cranium, and face. The aim of this study is to understand optimal osteotomy locations, dimensions, and force requirements for surgical operations of unicoronal craniosynostosis using a patient-specific finite element model and - at the same time - to evaluate the potential application of a new device made from Nitinol which was developed to expand the affected side of a unicoronal craniosynostosis skull without performing osteotomies. The model geometry was reconstructed using Simpleware ScanIP. The bone and sutures were modeled using elastic properties to perform the finite element analyses in MSc Marc software. The simulation results showed that expanding the cranium without osteotomy requires a significant amount of force. Therefore, expansion of the cranium achieved by Nitinol devices may not be sufficient to correct the deformity. Moreover, the size and locations of the osteotomies are crucial for an optimal outcome from surgical operations in unicoronal craniosynostosis.


Asunto(s)
Craneosinostosis/diagnóstico por imagen , Craneosinostosis/cirugía , Anomalías Maxilomandibulares/diagnóstico por imagen , Anomalías Maxilomandibulares/cirugía , Humanos , Lactante , Masculino , Osteotomía , Cráneo/cirugía , Cirugía Asistida por Computador
5.
J Craniofac Surg ; 31(1): e84-e89, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31634311

RESUMEN

Agnathia-otocephaly complex (AOC) is a rare malformation complex of the first pharyngeal arch that is characterized by agnathia/dysgnathia, microstomia, aglossia/hypoglossia and variable displacement of the ears. Only 11 post-infancy patients with severe AOC have been described in the literature, and the incidence of this malformation complex is estimated to be 1 per 70,000 births. In this brief clinical study, the authors describe the case of an 18-year-old female diagnosed with AOC who underwent a 3-step mandibular distraction protocol with an external distraction device. The surgical protocol the authors used was unique in that we first placed a tissue expander in the submental area to enlarge the skin envelope in an effort to mitigate skeletal relapse from soft tissue forces. Furthermore, the way in which the authors slowed the activation of the distraction device to allow for soft tissue healing behind the pins was a novel component of the patient's treatment. The 3-step mandibular distraction protocol the authors present in this study increased the length of the mandible by 20 mm, and nearly doubled the size of the patient's mandible from an initial volume of 3.62 cm to a post-operative volume of 6.89 cm. Future surgeries will aim to improve the function of our patient's expanded mandible. Most important of all, the surgical treatment authors are presenting led to a significant improvement in our patient's physical appearance and 3d quality of life.


Asunto(s)
Anomalías Craneofaciales/cirugía , Anomalías Maxilomandibulares/cirugía , Mandíbula/cirugía , Adolescente , Anomalías Craneofaciales/diagnóstico por imagen , Femenino , Humanos , Anomalías Maxilomandibulares/diagnóstico por imagen , Mandíbula/diagnóstico por imagen , Osteogénesis por Distracción , Calidad de Vida
6.
Rev. esp. cir. oral maxilofac ; 41(4): 197-201, oct.-dic. 2019. ilus, tab
Artículo en Español | IBECS | ID: ibc-191807

RESUMEN

La signatia es una rara malformación congénita en la que se encuentra una fusión ósea del maxilar con la mandíbula. Puede ser unilateral o completa y se caracteriza por la incapacidad de abrir la boca del recién nacido. Esta puede clasificarse de acuerdo con su presentación clínica. Las complicaciones de esta anomalía pueden ser muy graves: incompatibilidad con la vida, incapacidad de proteger la vía aérea, dificultades para la alimentación, así como alteraciones en el crecimiento. Se han referido casos con distintos abordajes, por lo que el protocolo terapéutico-quirúrgico estará dado según las particularidades de cada individuo. En el presente caso se hace referencia de un lactante femenino que se presentó con fusión del complejo cigomático-maxilar con la mandíbula unilateral, el abordaje y seguimiento


Syngnathia is a rare congenital malformation in which a fusion of the mandible with the maxilla is found, it can be unilateral or complete and is characterized by the inability to open the mouth of the newborn, this can be classified according to its clinical presentation. The complications of this anomaly can be inability to protect the airway, difficulties for feeding, as well as alterations in growth. There have referred cases with different approaches, thus the therapeutic-surgical protocol will be given according to the particularities of each individual. In the present case reference is made of female infant with unilateral maxillo-mandibular-zygomatic fusion, diagnosis and follow-up


Asunto(s)
Humanos , Femenino , Recién Nacido , Anomalías Maxilomandibulares/diagnóstico por imagen , Cigoma/anomalías , Reconstrucción Mandibular/métodos , Anomalías Maxilomandibulares/cirugía , Cigoma/cirugía , Impresión Tridimensional
7.
J Craniofac Surg ; 30(8): e784-e787, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31348202

RESUMEN

PURPOSE: The aim of the authors study is to demonstrate the soft tissues changes in the eyelid-brow area (ELBA) in patients with long-face syndrome after LeFort I osteotomy and impaction movements. MATERIALS AND METHODS: To perform this study the authors have analyzed retrospectively orthognathic patients with at least 1 years of completely follow-up. The inclusion criteria were: long-face syndrome according to Farkas' studies and vertical maxillary shortening movement without considering whether movements have been made in the other 2 planes of space (sagittal and horizontal).Orthognathic patients in which the maxillary impaction movement did not correlate to the long-face syndrome represented the control group. In this group too the authors did not consider if other movements were performed.Size and shape of the eyelid and the eyebrow was assessed on the frontal patients photos calibrated on the three-dimensional soft tissue volume imported from cone beam computed tomography.Two reference lines were taken: a horizontal line from the nasal point passing through both medial canthal angles and a perpendicular line through the pupil centre bilaterally. Then the measures were taken.The same operator (A.C.) took all of the measurements.In both groups, the preoperative measures were then compared with the postoperative ones. Then the soft tissue changes in both groups were compared. RESULTS: The results demonstrate different reaction of the ELBA after orthognathic surgery. The ELBA's position changes in long-face patients in a higher position after maxillary impaction. The authors did not obtain the same results in patients who do not have long-face syndrome. CONCLUSIONS: Repositioning skeletal bases in patients with long face causes a change in the ELBA's morphology.


Asunto(s)
Párpados/cirugía , Anomalías Maxilomandibulares/cirugía , Adolescente , Adulto , Tomografía Computarizada de Haz Cónico , Párpados/diagnóstico por imagen , Femenino , Humanos , Imagenología Tridimensional/métodos , Anomalías Maxilomandibulares/diagnóstico por imagen , Masculino , Maxilar/cirugía , Procedimientos Quirúrgicos Ortognáticos/métodos , Estudios Retrospectivos , Diente Impactado , Adulto Joven
8.
J Craniofac Surg ; 30(6): 1764-1766, 2019 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-30921067

RESUMEN

Congenital fusion of the jaws (syngnathia) is a rare and severe disorder. The authors report a case of bony fusion of the left mandible with the maxilla and zygomatic complex in a 5-day-old male who was not able to feed and open his mouth normally. Early surgery was performed to release the bony fusion on the tenth day of life. The authors present a new technique based on the intraoperative use of 3-dimensional surgical guides.


Asunto(s)
Anomalías Maxilomandibulares/cirugía , Mandíbula/cirugía , Maxilar/cirugía , Anomalías de la Boca/cirugía , Cigoma/cirugía , Humanos , Recién Nacido , Anomalías Maxilomandibulares/diagnóstico por imagen , Masculino , Mandíbula/diagnóstico por imagen , Maxilar/diagnóstico por imagen , Anomalías de la Boca/diagnóstico por imagen , Cigoma/diagnóstico por imagen
9.
Med. oral patol. oral cir. bucal (Internet) ; 24(1): e12-e19, ene. 2019. ilus, tab
Artículo en Inglés | IBECS | ID: ibc-180401

RESUMEN

Background: To evaluate 91 cases of Stafne bone defect (SBD) in panoramic radiographs (PR) to determine the prevalence of different SBD variants, considering age, gender, and side. Additionally, to assess the most frequent imaging features of SBD. Material and Methods: Participant data were collected from 91 SBD cases with PR imaging. First, SBDs were classified according to their location, as anterior, posterior, or ramus variant. SBD imaging features were classified according to radiographic imaging findings, assessing margins, degree of internal radiolucency, shape, topographic relationship between the defect and mandibular border, location of the defect according to mandibular teeth, and locularity. The topographic relationship between the SBD and the mandibular canal was described for the inferior variant only. Mean sizes were also described. Results: A total of 92 SBD cases were evaluated from 91 radiographs. One case presented multiple defects. Mean patient age was 60.80 years. Men were more affected than women. The most frequent SBD variant was the posterior variant, and the least frequent was the ramus variant. The most observed radiographic features were thick sclerotic bone margin in the entire contour of the defect, partially radiolucent internal content, oval shape, continuity with mandible base without discontinuity of mandible border, third molar region location, and unilocular shape. With the posterior variant only, the most common topographic relationship between the defect and the upper wall of the mandibular canal was the defect located below the upper wall and continuous with the inferior wall of the mandibular canal. Conclusions: The knowledge of common SBD radiographic imaging features in PR can help dental practitioners with the differential diagnosis of SBD


No disponible


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Radiografía Panorámica/métodos , Anomalías del Sistema Estomatognático/diagnóstico por imagen , Anomalías Maxilomandibulares/diagnóstico por imagen , Conductos Salivales/patología , Quistes Óseos/diagnóstico por imagen , Quiste Dentígero/diagnóstico por imagen , Diagnóstico Diferencial
10.
Biomed Res Int ; 2018: 4280312, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-30225253

RESUMEN

INTRODUCTION: Patients with chronic liver failure (CLF) are faced with many complications, because this organ is involved in various metabolic activities. Hepatic osteodystrophy is one of the major health issues encountered by this group of patients. The current study evaluated osteoporosis and bone changes in oral panoramic radiographies of cirrhotic patients. MATERIALS AND METHODS: In this study, 138 panoramic views of CLF patients, candidates for liver transplant (65 females, 73 males, aged 19-68 years) referred to Shiraz University Dental Clinic (Shiraz, Iran) for pretransplant oral examination, were evaluated. Also 138 healthy individuals (69 females, 69 males, aged 18-70 years) referred to the same clinic were examined. Abnormalities such as osteoporosis, pathologic radiolucencies, pathologic calcifications, tonsilloliths, condylar degeneration, and other findings in the alveolar bones were recorded. RESULTS: Osteoporosis was a common finding in CLF patients (p<0.001), and the probability of detecting low bone density in the panoramic view was 20.37 times higher among patients than healthy subjects. The probability of detecting pathologic jaw radiolucencies was 8.92 times higher in the case group than in the controls (p<0.001). Other bone abnormalities such as condylar degeneration and idiopathic osteosclerosis were also more prevalent in CLF patients compared to healthy subjects (p<0.001). CONCLUSION: Cirrhotic patients are prone to osteoporosis of the alveolar bones. Also, pathologic jaw radiolucencies as a result of oral infections are more prevalent in this group of patients. Routine oral panoramic views are acceptable and cost-effective radiographies for use in detecting such abnormalities in the alveolar bones as well as overall dental health. These findings also support the importance of dental health examinations prior to liver transplantation to reduce the risk of organ rejection.


Asunto(s)
Enfermedad Hepática en Estado Terminal/complicaciones , Anomalías Maxilomandibulares/diagnóstico por imagen , Osteoporosis/diagnóstico por imagen , Radiografía Panorámica , Adolescente , Adulto , Anciano , Densidad Ósea , Estudios Transversales , Femenino , Humanos , Irán , Anomalías Maxilomandibulares/complicaciones , Masculino , Mandíbula , Persona de Mediana Edad , Osteoporosis/complicaciones , Adulto Joven
11.
J Craniofac Surg ; 29(6): 1596-1600, 2018 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-29863549

RESUMEN

The Richieri-Costa-Pereira syndrome (RCPS) is an autosomal-recessive acrofacial dysostosis caused by mutations in EIF4A3, characterized by mandibular cleft comprising other craniofacial anomalies and limb defects such as cleft palate/Robin Sequence, microstomia, absence of mandibular central incisors, minor ear anomalies, clubfeet and first and 5 ray defects. The findings from this study are useful for better understanding the morphological consequences of disorders of EIF4A3, and having a better picture of the anatomic characteristics of the syndrome for a better therapeutic planning. Twenty-four angular and linear variables were measured to assess anteroposterior and vertical (superior-inferior) position of the cranial base, maxilla, mandible, and facial profile. The cephalometric radiographic analysis was performed on 9 individuals with RCPS, obtained at a mean age of 10.3 years, and compared with randomly selected age-matched 9 controls, without clefts and with well-balanced faces, with mean age of 10.6 years (both groups range 8.1 to 13.7 years). t test was used for analysis of means and Levene test for equality of variances. The syndrome group presented severe mandibular hypoplasia and retrognathism (P = 0.009, P = 0.001), greater facial convexity (N'PnPog and N'SnPog, P < 0.05) in syndrome group compared with the control group (P = 0.003, P = 0.004). In conclusion, in the RCPS group, most craniofacial defects affect the lower facial third, considering the severely affected mandible.


Asunto(s)
Pie Equinovaro/diagnóstico por imagen , Deformidades Congénitas de la Mano/diagnóstico por imagen , Anomalías Maxilomandibulares/diagnóstico por imagen , Síndrome de Pierre Robin/diagnóstico por imagen , Cráneo/diagnóstico por imagen , Adolescente , Estudios de Casos y Controles , Cefalometría , Niño , Pie Equinovaro/patología , Femenino , Deformidades Congénitas de la Mano/patología , Humanos , Anomalías Maxilomandibulares/patología , Masculino , Síndrome de Pierre Robin/patología , Cráneo/patología
12.
Cleft Palate Craniofac J ; 55(5): 778-786, 2018 05.
Artículo en Inglés | MEDLINE | ID: mdl-29665341

RESUMEN

Atypical craniofacial clefts of the upper facial region have been well documented; however, the mandibular clefts remain rare and reported as isolated case reports. We report a case of a median mandibular cleft within the context of a Tessier 0-14 axis that we have followed over a 5-year period without surgical/orthodontic intervention. The mandibular symphysis cleft remained open without evidence of the fusion, in contrast to ossification of the metopic dysraphism. Within this context, we present a review of the median mandibular cleft cases from 1819 to 2015.


Asunto(s)
Anomalías Craneofaciales/diagnóstico por imagen , Imagenología Tridimensional/métodos , Anomalías Maxilomandibulares/clasificación , Anomalías Maxilomandibulares/diagnóstico por imagen , Mandíbula/anomalías , Tomografía Computarizada por Rayos X/métodos , Niño , Preescolar , Humanos , Masculino
13.
Indian J Ophthalmol ; 66(3): 383-388, 2018 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-29480247

RESUMEN

PURPOSE: To study the features of upper eyelid in healthy individual and different types of congenital ptosis in the Indian population using ultrasound biomicroscopy (UBM). METHODS: This was a prospective observational study at a tertiary care center. Eyelid structure of healthy individuals with no eyelid abnormalities (n = 19); simple congenital ptosis (n = 33) cases; Marcus Gunn jaw-winking ptosis (MGJWP, n = 7) cases, and blepharophimosis-ptosis-epicanthus inversus syndrome (BPES, n = 20) cases were studied on a vertical UBM scan using 50-MHz probe. Lid-thickness, tarsal-thickness, orbicularis oculi and levator-Muller-orbital septum-conjunctival (LMSC) complex were measured in primary gaze. Comparison was made between four groups and results were statistically analyzed using ANOVA test. In normal individuals, LMSC measurements were repeated in down-gaze imaging. RESULTS: Skin with subcutaneous tissue, LMSC complex and pre-aponeurotic fat-pad appeared echodense while orbicularis oculi and tarsus appeared echolucent. In primary gaze, mean thickness (± standard deviation) of the eyelid, tarsus, orbicularis oculi and LMSC, respectively, were: 1.612 ± 0.205, 0.907 ± 0.098, 0.336 ± 0.083, and 0.785 ± 0.135 mm in normal individual. LMSC showed 46.64% increase in thickness on down-gaze. The mean eyelid thickness and LMSC were thicker in MGJWP and BPES as compared to normal. In different types of congenital ptosis cases, various patterns of UBM imaging were observed. CONCLUSION: UBM allows noninvasive imaging of eyelid structures with good anatomical correspondence in normal eyelids and study the structural alterations of eyelids in different types of congenital ptosis. UBM can be used to highlight the anatomical difference in normal eyelids that may help modify the surgery for better cosmetic outcomes. Furthermore, it has the potential to be used in preoperative evaluation and operative planning in certain types of acquired ptosis, which needs to be evaluated.


Asunto(s)
Blefarofimosis/diagnóstico por imagen , Blefaroptosis/diagnóstico por imagen , Párpados/diagnóstico por imagen , Cardiopatías Congénitas/diagnóstico por imagen , Anomalías Maxilomandibulares/diagnóstico por imagen , Microscopía Acústica , Enfermedades del Sistema Nervioso/diagnóstico por imagen , Anomalías Cutáneas/diagnóstico por imagen , Anomalías Urogenitales/diagnóstico por imagen , Adolescente , Adulto , Pueblo Asiatico/etnología , Blefarofimosis/etnología , Blefaroptosis/etnología , Niño , Femenino , Voluntarios Sanos , Cardiopatías Congénitas/etnología , Humanos , India , Anomalías Maxilomandibulares/etnología , Masculino , Enfermedades del Sistema Nervioso/etnología , Estudios Prospectivos , Reflejo Anormal , Anomalías Cutáneas/etnología , Anomalías Urogenitales/etnología , Adulto Joven
14.
Int J Oral Maxillofac Surg ; 47(6): 708-714, 2018 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-29246423

RESUMEN

The aim of this study was to evaluate the precision of bimaxillary surgery performed to correct vertical maxillary excess, when the procedure is sequenced with mandibular surgery first or maxillary surgery first. Thirty-two patients, divided into two groups, were included in this retrospective study. Group 1 comprised patients who received bimaxillary surgery following the classical sequence with repositioning of the maxilla first. Patients in group 2 received bimaxillary surgery, but the mandible was operated on first. The precision of the maxillomandibular repositioning was determined by comparison of the digital prediction and postoperative tracings superimposed on the cranial base. The data were tabulated and analyzed statistically. In this sample, both surgical sequences provided adequate clinical accuracy. The classical sequence, repositioning the maxilla first, resulted in greater accuracy for A-point and the upper incisor edge vertical position. Repositioning the mandible first allowed greater precision in the vertical position of pogonion. In conclusion, although both surgical sequences may be used, repositioning the mandible first will result in greater imprecision in relation to the predictive tracing than repositioning the maxilla first. The classical sequence resulted in greater accuracy in the vertical position of the maxilla, which is key for aesthetics.


Asunto(s)
Anomalías Maxilomandibulares/cirugía , Maxilar/anomalías , Maxilar/cirugía , Procedimientos Quirúrgicos Ortognáticos , Adolescente , Adulto , Cefalometría , Estética Dental , Femenino , Humanos , Anomalías Maxilomandibulares/diagnóstico por imagen , Masculino , Maxilar/diagnóstico por imagen , Persona de Mediana Edad , Modelos Dentales , Radiografía Panorámica , Reproducibilidad de los Resultados , Estudios Retrospectivos , Resultado del Tratamiento
15.
J Craniofac Surg ; 29(2): 342-346, 2018 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-29239924

RESUMEN

BACKGROUND: This study aimed to evaluate a novel subtractive method for the precise calculation of alveolar cleft defect volume before surgery using the three-dimensional imaging software Mimics. METHODS: Ten patients (3 female, 7 male, age range 8-12 years) with unilateral alveolar cleft were enrolled in the study. Preoperative helical computed tomography scans were performed for all patients. A new subtractive method was introduced to precisely calculate the alveolar cleft defect volume before surgery with the aid of Mimics. The DICOM data of every patient were processed using the subtractive method. Statistical analyses were performed using Pearson's correlation test and t test. RESULTS: The mean volume of the alveolar cleft defect was 1811.97 ±â€Š817.90 mm. The mean time spent to calculate an alveolar cleft defect volume was 60.60 ±â€Š11.67 minutes. The Pearson correlation test (r = 0.38, P = 0.279) indicated a poor correlation between alveolar cleft defect volume and calculation time. CONCLUSIONS: Preoperative knowledge of defect volume is crucial in alveolar cleft repair. Accurate estimation of graft volume in alveolar cleft patients can be performed using this new subtractive method. Compared with previous methods, this new subtractive method is time-saving and suitable for both unilateral and bilateral clefts. Surgeons can use this method to design a surgical plan for each patient before surgery within a short time, and with less cost.


Asunto(s)
Proceso Alveolar , Anomalías Maxilomandibulares , Tomografía Computarizada de Haz Cónico Espiral , Técnica de Sustracción , Cirugía Asistida por Computador , Proceso Alveolar/diagnóstico por imagen , Proceso Alveolar/patología , Proceso Alveolar/cirugía , Niño , Femenino , Humanos , Anomalías Maxilomandibulares/diagnóstico por imagen , Anomalías Maxilomandibulares/patología , Anomalías Maxilomandibulares/cirugía , Masculino
16.
J Dent Res ; 96(13): 1526-1534, 2017 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-28644737

RESUMEN

Achondroplasia is the most common genetic form of human dwarfism, characterized by midfacial hypoplasia resulting in occlusal abnormality and foramen magnum stenosis, leading to serious neurologic complications and hydrocephalus. Currently, surgery is the only way to manage jaw deformity, neurologic complications, and hydrocephalus in patients with achondroplasia. We previously showed that C-type natriuretic peptide (CNP) is a potent stimulator of endochondral bone growth of long bones and vertebrae and is also a potent stimulator in the craniofacial region, which is crucial for midfacial skeletogenesis. In this study, we analyzed craniofacial morphology in a mouse model of achondroplasia, in which fibroblast growth factor receptor 3 (FGFR3) is specifically activated in cartilage ( Fgfr3ach mice), and investigated the mechanisms of jaw deformities caused by this mutation. Furthermore, we analyzed the effect of CNP on the maxillofacial area in these animals. Fgfr3ach mice exhibited midfacial hypoplasia, especially in the sagittal direction, caused by impaired endochondral ossification in craniofacial cartilage and by premature closure of the spheno-occipital synchondrosis, an important growth center in craniomaxillofacial skeletogenesis. We crossed Fgfr3ach mice with transgenic mice in which CNP is expressed in the liver under the control of the human serum amyloid-P component promoter, resulting in elevated levels of circulatory CNP ( Fgfr3ach/SAP-Nppc-Tg mice). In the progeny, midfacial hypoplasia in the sagittal direction observed in Fgfr3ach mice was improved significantly by restoring the thickness of synchondrosis and promoting proliferation of chondrocytes in the craniofacial cartilage. In addition, the foramen magnum stenosis observed in Fgfr3ach mice was significantly ameliorated in Fgfr3ach/SAP-Nppc-Tg mice due to enhanced endochondral bone growth of the anterior intraoccipital synchondrosis. These results clearly demonstrate the therapeutic potential of CNP for treatment of midfacial hypoplasia and foramen magnum stenosis in achondroplasia.


Asunto(s)
Acondroplasia/tratamiento farmacológico , Anomalías Maxilomandibulares/tratamiento farmacológico , Péptido Natriurético Tipo-C/sangre , Péptido Natriurético Tipo-C/farmacología , Acondroplasia/diagnóstico por imagen , Acondroplasia/patología , Animales , Etiquetado Corte-Fin in Situ , Anomalías Maxilomandibulares/diagnóstico por imagen , Anomalías Maxilomandibulares/patología , Ratones , Osteogénesis/efectos de los fármacos , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Microtomografía por Rayos X
17.
J Otolaryngol Head Neck Surg ; 46(1): 31, 2017 Apr 11.
Artículo en Inglés | MEDLINE | ID: mdl-28399908

RESUMEN

BACKGROUND: The surgical excision of anatomic obstructions such as adenoids, palatine or lingual tonsils are commonly performed in children with sleep disordered breathing (SDB). Imaging studies measuring airway changes post-surgery in the SDB pediatric population are scarce, rarely addresses the nasal cavity, and are based on global measures (e.g. volume) that do not represent the complexity of the upper airway anatomy. The purpose of this pilot is to test the feasibility in using cone beam CT (CBCT) to analyze the nasal and pharyngeal airway space post-surgery using meaningful methods of analyses, and correlating imaging findings with clinical outcomes in children with SDB symptoms and maxillary-mandibular disproportion. METHODS: Twelve non-syndromic children with SDB symptoms and jaw disproportions were evaluated by interdisciplinary airway team before and after upper airway surgery. CBCT and OSA-18 quality of life questionnaire pre and post-operatively were completed. Conventional and new airway variables were measured based on 3D models of the upper airways and correlated with OSA-18. Conventional measures include volume, surface area, and cross-sectional area. New airway measures include constriction and patency; point-based analyses. RESULTS: Eight females and four males were 8.8 ± 2 years with mean BMI of 18.7 ± 3. OSA-18 improved, median (lower quartile-upper quartile) from 64.2 (54.7-79.5) to 37.6 (28.7-43) postoperatively, p < 0.001. The median of all airway measures improved however with very wide range. Subjects with the smallest amounts of constriction relief and/or gain in airway patency presented with least improvement in OSA-18. New airway measures show strong correlation with changes in OSA-18 (ρ = 0.44 to 0.71) whereas conventional measures showed very weak correlation (ρ = -0.04 to 0.37). CONCLUSIONS: Using point-based analyses, new airway measures better explained changes in clinical symptoms compared to conventional measures. Airway patency gained by at least 150% and constriction relief by at least 15% showed marked improvement in OSA-18 by 40-55%, after surgery in the tested cohort.


Asunto(s)
Tomografía Computarizada de Haz Cónico , Anomalías Maxilomandibulares/diagnóstico por imagen , Anomalías Maxilomandibulares/cirugía , Síndromes de la Apnea del Sueño/diagnóstico por imagen , Síndromes de la Apnea del Sueño/cirugía , Adenoidectomía , Niño , Preescolar , Estudios de Cohortes , Estudios de Factibilidad , Femenino , Humanos , Anomalías Maxilomandibulares/complicaciones , Masculino , Proyectos Piloto , Calidad de Vida , Síndromes de la Apnea del Sueño/etiología , Tonsilectomía , Resultado del Tratamiento
18.
Am J Orthod Dentofacial Orthop ; 151(2): 324-334, 2017 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-28153162

RESUMEN

INTRODUCTION: The purpose of this study was to evaluate the hypothesis that 3-dimensional mandibular morphology is correlated with condylar movement in patients with mandibular asymmetry. METHODS: Subjects were classified into 2 groups (n = 25 each): mandibular asymmetry with a menton deviation greater than 4 mm and no mandibular asymmetry with a menton deviation less than 4 mm. Linear and volumetric measurements of 3-dimensional mandibular morphology were recorded using computed tomography. Mandibular functional movement was recorded by computerized axiography (CADIAX; Gamma Dental, Klosterneuburg, Austria), and condylar path length, sagittal condylar inclination, and transverse condylar inclination on protrusion were measured. We calculated side-to-side asymmetry (shifted side vs nonshifted side) in mandibular morphology and assessed condylar movement by using an asymmetry ratio (nonshifted side/shifted side). RESULTS: Significant differences in mandibular morphology and condylar movement were found between the 2 groups. In the group with menton deviation greater than 4 mm, significant correlations were found between the asymmetry ratio of mandibular morphology and condylar movement: ie, condylar path length and transverse condylar inclination. No significant correlations were found between any of these measurements in the group with menton deviation less than 4 mm. CONCLUSIONS: In support of our hypothesis, the results suggested that 3-dimensional mandibular morphologic asymmetry is associated with condylar movement in subjects with mandibular asymmetry.


Asunto(s)
Imagenología Tridimensional , Anomalías Maxilomandibulares/diagnóstico por imagen , Anomalías Maxilomandibulares/fisiopatología , Cóndilo Mandibular/diagnóstico por imagen , Cóndilo Mandibular/fisiopatología , Movimiento , Tomografía Computarizada por Rayos X , Adulto , Femenino , Humanos , Masculino , Mandíbula/anomalías , Adulto Joven
19.
Rev. ADM ; 74(1): 25-31, ene.-feb. 2017. tab, graf
Artículo en Español | LILACS | ID: biblio-869349

RESUMEN

Introducción: la valoración radiográfica rutinaria en la práctica odontológicaes esencial para un adecuado diagnóstico y plan de tratamiento. Laortopantomografía o radiografía panorámica es una técnica simple, rápida, de bajo costo y a una baja dosis de radiación. Objetivos: Caracterizarlos hallazgos incidentales más comunes en radiografías panorámicas de pacientes adultos jóvenes de una clínica dental universitaria. Materialy métodos: Se realizó un estudio descriptivo, retrospectivo, de cortetransversal de radiografías panorámicas digitales, tomadas e interpretadas de manera ciega, explorando alteraciones óseas y anomalías dentales. Se realizó la caracterización de su presentación por género de los participantes. Para el análisis de datos se utilizaron pruebas no paramétricas (la prueba χ2, exacta de Fisher y binomial). Resultados: Se tomaron 98 radiografías del mismo número de pacientes, con edad promedio de 19.45 años, predominando las mujeres (69/70.40 por ciento), solteros (94/95.91 por ciento) y de zona urbana (77/78.57 por ciento). Existieron 387 alteraciones, 268 (69.25 por ciento) enmujeres, y 119 (30.74 por ciento) en hombres, con un promedio de 3.88 y 4.10 alteraciones por paciente, respectivamente. La distribución mostró en total 122 (31.52 por ciento) lesiones a nivel de senos maxilares, 124 (32.04 por ciento) en fosasnasales, 16 (4.13 por ciento) lesiones radiolúcidas u opacas, y 125 (32.29 por ciento) anomalías asociadas a retención dental. La comparación de acuerdo al género mostró diferencia (p ≤ 0.001) en la frecuencia de alteraciones, en todos los casos determinada por las mujeres, para cada sitio y tipo de lesión presentada. Conclusiones: El valor de la radiografía panorámica para detectar anomalías de estructuras orofaciales demostró en este estudio su utilidad en la práctica asistencial desde una perspectiva epidemiológica.


Background: doutine dental X-Ray assessment in dental practice isessential for proper diagnosis and treatment. Orthopantomographyor panoramic radiography is a quick, simple, low-cost, and low-doseradiation technique. Objective: To describe the most common incidentalfi ndings on the panoramic radiographs of young adult patients ata university dental clinic. Material and methods: A descriptive,retrospective, cross-sectional study was carried out, in which digitalpanoramic radiographs were taken and interpreted blindly to examinebone disorders, and dental anomalies, and the prevalence of theseaccording to the gender of the participants. Nonparametric statistics(Chi-square χ2, Fisher’s exact, and binomial tests) were used for dataanalysis. Results: 98 radiographs were taken of the same number ofpatients with a mean age of 19.45 years, most of whom were women(69/70.40%), single (94/95.91%), and from urban areas (77/78.57%). 387alterations were found, 268 (69.25%) in women and 119 (30.74%) in men,with an average of 3.88 and 4.10 alterations per patient, respectively. Thedistribution presented a total of 122 (31.52 %) lesions in the maxillarysinus, 124 (32.04 %) in the nostrils, 16 (4.13 %) radiolucent or opaquelesions, and 125 (32.29%) anomalies associated with tooth retention. Acomparison by sex revealed a diff erence (p < 0.001) in the frequency ofalterations, which was greater in women for all sites and types of lesion.Conclusions: The study showed the usefulness of panoramic radiographyin clinical practice to detect anomalies of the orofacial structure from anepidemiological perspective.


Asunto(s)
Humanos , Masculino , Adolescente , Adulto , Femenino , Adulto Joven , Anomalías Dentarias/clasificación , Anomalías Dentarias/diagnóstico por imagen , Diagnóstico por Imagen , Radiografía Panorámica/métodos , Estudiantes de Odontología , Distribución por Edad y Sexo , Anomalías Maxilomandibulares/clasificación , Anomalías Maxilomandibulares/diagnóstico por imagen , Estudios Transversales , Epidemiología Descriptiva , México , Estudios Retrospectivos , Interpretación Estadística de Datos
20.
Int J Oral Maxillofac Surg ; 45(8): 985-91, 2016 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-26972158

RESUMEN

The aim of this study was to determine the relationships among bone properties, bone metabolic markers, and types of jaw deformity. The subjects were 55 female patients with jaw deformities. Skeletal morphology was examined using lateral cephalograms, and the patients were divided into three groups according to the type of anteroposterior skeletal pattern. Serum osteocalcin, bone alkaline phosphatase, and tartrate-resistant acid phosphatase isoform 5b, as well as deoxypyridinoline in urine, were measured as bone metabolic markers. Quantitative ultrasound (QUS) measurements were used to assess bone properties at the calcaneal bone. The bone volume and bone density of the condylar process were measured in 43 patients by computed tomography. There were no significant differences in bone metabolic markers and QUS parameters between the groups, although bone formation and resorption markers tended to be higher in patients with a protrusive mandible. On the other hand, patients with mandibular retrusion had a higher tendency to have small and dense condylar processes. In conclusion, the results suggest that growth depression or a degenerative change in the mandibular condyle is involved in the pathogenesis of mandibular retrusion, although risk factors for progressive condylar resorption were not determined.


Asunto(s)
Huesos/metabolismo , Anomalías Maxilomandibulares/diagnóstico por imagen , Anomalías Maxilomandibulares/metabolismo , Fosfatasa Ácida , Adolescente , Adulto , Fosfatasa Alcalina/sangre , Aminoácidos/orina , Biomarcadores/sangre , Biomarcadores/orina , Densidad Ósea , Cefalometría/métodos , Femenino , Humanos , Osteocalcina/sangre , Estudios Prospectivos , Fosfatasa Ácida Tartratorresistente/sangre , Adulto Joven
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