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1.
Rev Esp Enferm Dig ; 116(4): 225-226, 2024 Apr.
Article En | MEDLINE | ID: mdl-37170586

It is rare to find a small bowel tumour presenting as intestinal obstruction. This type of cancer is an extremely unusual condition often misdiagnosed until late stages. We report the case of a patient with persistent vomiting secondary to an obstructing jejunal adenocarcinoma not related to intestinal bowel disease. After resection and chemotherapy treatment a huge mass was detected in the left ovary. The anatomopathological findings confirmed a metastatic cancer consequent to the jejunal adenocarcinoma previously resected. This case illustrates a successful outcome of a jejunal adenocarcinoma with very poor prognosis after a extremely unusual ovarian metastasis. It is highly important to suspect other causes than intestinal bowel disease when doing a differential diagnosis in a young patient presenting with clinical symptoms of intestinal obstruction.


Adenocarcinoma , Duodenal Neoplasms , Intestinal Obstruction , Jejunal Neoplasms , Ovarian Neoplasms , Female , Humans , Adenocarcinoma/surgery , Duodenal Neoplasms/complications , Intestinal Obstruction/etiology , Intestine, Small/pathology , Jejunal Neoplasms/diagnostic imaging , Jejunal Neoplasms/surgery , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/secondary , Ovarian Neoplasms/surgery , Adult
2.
Clin Nucl Med ; 48(10): 902-904, 2023 Oct 01.
Article En | MEDLINE | ID: mdl-37682607

ABSTRACT: Follicular dendritic cell sarcoma of the gastrointestinal tract is a rare malignancy. We describe contrast-enhanced CT and FDG PET/CT findings in a case of jejunal follicular dendritic cell sarcoma with hepatic metastasis. The primary jejunal tumor showed inhomogeneous enhancement on contrast-enhanced CT and intense FDG uptake on PET/CT mimicking adenocarcinoma or gastrointestinal stromal tumor. The hepatic metastatic tumor showed hypovascularity on contrast-enhanced CT and mild FDG uptake on PET/CT. This case indicates that follicular dendritic cell sarcoma should be included in the differential diagnosis of the hypermetabolic intestinal lesions.


Dendritic Cell Sarcoma, Follicular , Jejunal Neoplasms , Liver Neoplasms , Dendritic Cell Sarcoma, Follicular/diagnostic imaging , Dendritic Cell Sarcoma, Follicular/pathology , Jejunal Neoplasms/diagnostic imaging , Jejunal Neoplasms/pathology , Liver Neoplasms/secondary , Positron Emission Tomography Computed Tomography , Humans , Male , Middle Aged
3.
Clin J Gastroenterol ; 16(1): 32-38, 2023 Feb.
Article En | MEDLINE | ID: mdl-36369458

Small intestinal lipomas are rare, but may cause obscure gastrointestinal bleeding. The endoscopic unroofing technique excises only the upper third of the lipoma and allows both histological confirmation and complete treatment with minimal risk of perforation. We present a rare case of obscure gastrointestinal bleeding caused by a jejunal lipoma. A 75-year-old man on antiplatelet therapy presented to our department with melena and anemia. Computed tomography revealed he had a 45-mm jejunal submucosal tumor with fat attenuation. Endoscopic resection using an endoscopic unroofing technique with double balloon enteroscopy was successfully performed. The tumor was confirmed to be a lipoma.


Jejunal Neoplasms , Lipoma , Male , Humans , Aged , Double-Balloon Enteroscopy/adverse effects , Gastrointestinal Hemorrhage/diagnostic imaging , Gastrointestinal Hemorrhage/etiology , Gastrointestinal Hemorrhage/surgery , Jejunum/surgery , Jejunum/pathology , Jejunal Neoplasms/complications , Jejunal Neoplasms/diagnostic imaging , Jejunal Neoplasms/surgery , Lipoma/complications , Lipoma/diagnostic imaging , Lipoma/surgery
6.
J Pak Med Assoc ; 71(4): 1255-1257, 2021 Apr.
Article En | MEDLINE | ID: mdl-34125783

Small bowel malignancy (SBM) is a rare malignancy in the gastrointestinal tract. Duodenum is the most commonly involved segment and the most common histological subtype is adenocarcinoma (40%). Due to a lack of screening tools and vague symptoms, its clinical detection is very challenging. A 27-year-old man presented at the surgical emergency of Lahore General Hospital in February 2019 with non-specific gastrointestinal symptoms (vomiting, abdominal pain), for which he had previously visited the hospital multiple times. Later, on further workup, he had been diagnosed as a case of intussusception on CT scan. On exploration, he had an impassable stricture in the jejunum. Resection anastomosis of the jejunum was done, but later, on histopathology it turned out to be adenocarcinoma. Adenocarcinoma of the small bowel is a rare entity, and, particularly in Pakistan, the available literature is limited. SBM should be included in the differentials of patients with vague abdominal symptoms. Future studies for the evaluation of new investigations and treatment modalities should be encouraged to improve the overall outcome of the patients.


Adenocarcinoma , Intussusception , Jejunal Neoplasms , Adenocarcinoma/diagnosis , Adenocarcinoma/surgery , Adult , Humans , Intestine, Small/diagnostic imaging , Intestine, Small/surgery , Jejunal Neoplasms/diagnostic imaging , Jejunal Neoplasms/surgery , Male , Pakistan
11.
Rev. inf. cient ; 99(5): 487-493, graf
Article Es | LILACS, CUMED | ID: biblio-1139211

RESUMEN Se presentó el caso de un paciente de 49 años de edad, que acudió a la consulta de Medicina Interna del Hospital General Docente "Dr. Agostinho Neto" por perder unas 20 libras de peso en dos meses y presentar heces fecales con aspecto aparente a "borra de café". El examen físico reveló desnutrición ligera y mucosas hipocoloreas. El ultrasonido abdominal mostró en hipocondrio y flanco izquierdo una imagen hipoecogénica heterogénea polilobulada que midió 68x61 mm con aspecto de paquete adenomegálico. En la tomografía computarizada de abdomen se identificó una imagen con densidad entre 33 y 57 UH, de 100 x 80 mm, polilobulada en topografía del yeyuno, que con el estudio contrastado realzó hasta 67 UH con aspecto tumoral. Se realizó resección quirúrgica del tumor con anastomosis termino-terminal. La biopsia informó fibroleiomiosarcoma. Se concluye que el estudio de las imágenes resulta útil para el diagnóstico de esta enfermedad.


ABSTRACT A 49-year-old patient presented to the internal medicine consultation office at the "Dr. Agostinho Neto" General teaching Hospital because of weight loss (20 pounds) and black stools in a period of 2 months before the evaluation. The physical examination revealed mild malnutrition and hypochlorous mucous membranes. The abdominal ultrasound image in the left hypochondrium showed a heterogeneous - polylobate - hypoechogenic mass measuring 68 x 61 mm with appearance of an adenomelagia. Computed tomography (CT) scan of the abdomen revealed an image with a density of 33 and 57 Hounsfield units (HU), measured 100 mm by 80 mm, polylobulated in jejunum topography, which with the contrasted study enhanced up to 67 UH with a tumor appearance. Surgical resection of the tumor with termino-terminal anastomosis was performed. Tumor biopsy diagnosed leiomyosarcoma. It was concluded that the study of the images was useful for the diagnosis of this disease.


Humans , Middle Aged , Sarcoma/diagnostic imaging , Jejunal Neoplasms/diagnostic imaging
13.
BMC Gastroenterol ; 20(1): 112, 2020 Apr 16.
Article En | MEDLINE | ID: mdl-32299377

BACKGROUND: Small bowel adenocarcinoma (SBA) is a rare malignancy that primarily occurs in the duodenum. Multiple synchronous SBA is unique rare and difficult to diagnose due to non-specific disease presentation. Protocols to identify multiple synchronous SBA during early disease stages are urgently required. CASE PRESENTATION: An elderly man experienced left lower abdominal pain and melena for 3 months. Abdominal CT showed thickening of the multiple segmental small intestinal walls. As the patient had pulmonary tuberculosis simultaneously, he was misdiagnosis as intestinal tuberculosis and received anti-spasm therapy. The treatment delayed radical resection surgery and the patient underwent palliative segmental resection of the jejunum after 4 months due to intestinal obstruction. Resected specimens showed multiple synchronous SBA (five tumors). The patient accepted chemotherapy postoperatively. Six months postoperatively, the patient died of brain metastasis. CONCLUSIONS: We highlight how multiple synchronous SBA is rare and easily misdiagnosed. We should rule out multiple synchronous SBA when diagnosing intestinal diseases (e.g. inflammatory bowel disease, IBS). Intestinal tuberculosis may also be one of the risk factors for multiple synchronous SBA. High-risk patients should be assessed for known tumor makers, and receive gastroscopy, enteroscopy or capsule endoscopy. Doctors should obtain the pathology under endoscopy to the greatest possible degree. For suspected patients, laparotomy should be performed.


Adenocarcinoma/diagnostic imaging , Jejunal Neoplasms/diagnostic imaging , Neoplasms, Multiple Primary/diagnostic imaging , Adenocarcinoma/complications , Adenocarcinoma/secondary , Aged , Diagnostic Errors , Fatal Outcome , Humans , Jejunal Neoplasms/complications , Jejunal Neoplasms/pathology , Male , Melena/etiology , Neoplasms, Multiple Primary/complications , Neoplasms, Multiple Primary/pathology , Tomography, X-Ray Computed , Tuberculosis, Gastrointestinal/diagnostic imaging , Tuberculosis, Pulmonary/complications
16.
Hell J Nucl Med ; 23(1): 81-85, 2020.
Article En | MEDLINE | ID: mdl-32222734

A 69 year old patient was admitted to hospital with massive gastrointestinal hemorrhage. The clinical presentation of the patient, except for bleeding, was dominated by the presence of neurofibromatosis type 1 - Von Recklinghausen disease. The patient was referred to multislice computed tomography (CT) angiography, magnetic resonance imaging (MRI), esophagogastroduodenoscopy and colonoscopy, which were performed without successful detection of the bleeding site. The MRI examination showed the existence of a tumor located in the small pelvis. After that, gastrointestinal bleeding scintigraphy (GIBS) with technetium-99m (99mTc) pyrophosphate in vivo labeled erythrocytes was done. Gastrointestinal bleeding scintigraphy showed active intraluminal bleeding from the projection of jejunum, which flowed through the small intestine to the descending colon and the sigmoidal and rectal segment of the colon. Surgical resection of the abdomen revealed the existence of tumors in the jejunum with active bleeding and resection and anastomosis was done. Histopathological verification showed intestinal neurofibroma. In this case GIBS showed usefulness in proving the existence of active bleeding in the small intestine and its localization, and it was of a great help in planning the surgical treatment of a patient.


Gastrointestinal Hemorrhage/complications , Jejunal Neoplasms/complications , Jejunal Neoplasms/diagnostic imaging , Neurofibroma/complications , Neurofibroma/diagnostic imaging , Neurofibromatosis 1/complications , Computed Tomography Angiography , Female , Humans , Radionuclide Imaging
17.
Medicine (Baltimore) ; 99(4): e18863, 2020 Jan.
Article En | MEDLINE | ID: mdl-31977886

RATIONALE: Hemolymphangioma is a benign tumor comprised of the newly-formed lymph spaces and blood vessels, which can usually be found in the head and neck of the affected children. There are few reports regarding cases with hemolymphangioma in small intestine, spleen, esophagus, and other organs. PATIENT CONCERNS: Herein, a 55-year-old woman was presented in this study, she had complained of discomfort in the right upper abdomen for 2 months, and was discovered with a space-occupying lesion in proximal jejunum on computed tomography (CT). Eventually, the lesions were confirmed through double-balloon enteroscopy (DBE) to be located in the jejunum 60 cm away from the Treitz ligament. DIAGNOSE: Subsequently, the small intestine was partially resected, and postoperative pathology had confirmed the diagnosis of small intestinal hemolymphangioma. INTERVENTIONS: Excisional surgery of the lesion was planned. On surgery, the lesions were discovered to be about 33 cm to 22 cm when engorged the superficial vessels. No enlarged lymph nodes were seen at the root of the mesentery, and no obvious lesion was observed in the remaining small intestine. OUTCOMES: Follow-up for 6 months showed no recurrence. LESSONS: Hemolymphangioma lacks typical clinical symptoms, and the correct preoperative diagnosis of hemolymphangioma remains challenging. Due to the increasing use of endoscopic diagnostic techniques, it is expected that hemolymphangioma in gastrointestinal tract may be detected and endoluminal located before surgery more feasibly. This case report aimed to highlight the contributions of CT and DBE to an accurate preoperative diagnosis and surgical strategy planning.


Jejunal Neoplasms/diagnostic imaging , Jejunal Neoplasms/surgery , Lymphangioma/diagnostic imaging , Lymphangioma/surgery , Double-Balloon Enteroscopy , Female , Humans , Jejunal Neoplasms/pathology , Lymphangioma/pathology , Middle Aged , Tomography, X-Ray Computed
20.
Clin J Gastroenterol ; 13(3): 372-376, 2020 Jun.
Article En | MEDLINE | ID: mdl-31701367

Small bowel adenocarcinomas are rare. There is no definite consensus as to whether they should be treated in a manner similar to gastric or to colon cancer. We report the case of a young woman with a primary jejunal adenocarcinoma, bilateral ovary metastases, and peritoneal dissemination. First- and second-line chemotherapy for the gastric cancer failed. She was then treated with the immune checkpoint inhibitor nivolumab and had temporary improvement in her condition. To the best of our knowledge, this is the first case wherein nivolumab has been used to treat small bowel adenocarcinoma.


Adenocarcinoma/drug therapy , Antineoplastic Agents, Immunological/therapeutic use , Jejunal Neoplasms/drug therapy , Nivolumab/therapeutic use , Adenocarcinoma/diagnostic imaging , Adenocarcinoma/pathology , Adult , Female , Humans , Jejunal Neoplasms/diagnostic imaging , Jejunal Neoplasms/pathology , Jejunum/pathology , Ovarian Neoplasms/secondary , Tomography, X-Ray Computed
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