Associations of polygenic risk scores for smoking heaviness and lifetime cannabis use with tobacco and cannabis co-use trajectories among African Americans.

BACKGROUND: We aimed to identify distinct trajectories of tobacco, cannabis, and their co-use among African Americans, and to investigate whether these patterns were associated with polygenic risk scores (PRS) for tobacco and cannabis use. METHOD: Participants (N=428 participants; 50.9% male) were initially recruited for an elementary school-based prevention in a Mid-Atlantic city when they were in first grade. From ages 14-26, participants reported on their frequency of tobacco and cannabis use in the past year during annual assessments. DNA was collected from participants at age 21. PRS for smoking heaviness (i.e., cigarettes per day) and lifetime cannabis use were created based on genome-wide association study results derived from Liu et al. (2019) and Pasman et al. (2018), respectively. RESULTS: We identified five distinct trajectories of tobacco and cannabis co-use, including (1) Low Tobacco and Cannabis Use, (2) Adolescent Limited Tobacco and Cannabis Use, (3) Experimental Cannabis, Young Adult Increasing Tobacco, (4) Experimental Tobacco, Young Adult Increasing Cannabis, and (5) High, Chronic Tobacco and Cannabis Use. Compared to the Low Tobacco and Cannabis Use subgroup, individuals in the High, Chronic Tobacco and Cannabis Use subgroup had greater PRS for smoking heaviness, and individuals in the Experimental Cannabis, Young Adult Increasing Tobacco subgroup had higher PRS for lifetime cannabis use. CONCLUSIONS: Polygenic risk for lifetime cannabis use and smoking heaviness is associated with the developmental progression of tobacco and cannabis co-use among African Americans, furthering knowledge on the etiology of co-use in this population.

The relationship between depressed affect, parental monitoring, and sex on cannabis use among American Indian youth.

BACKGROUND AND OBJECTIVES: American Indian (AI) adolescents report higher rates of cannabis use than national US adolescents. Previous study examined interactive relationships between depressed affect and family factors on AI adolescent alcohol use. These factors have not been investigated for cannabis use. We examined whether parental monitoring dampened risk for cannabis use due to depressed affect, and potential moderation by sex. METHODS: We measured cannabis use, depressed affect, parental monitoring, and sex among reservation area AI youth among students in grades 7-12 attending 45 schools. We used censor-inflated regression models to identify parental monitoring as a moderator of the relationship between depressed affect and cannabis use. RESULTS: In the logistic portion of censor-inflated models, level of depressed affect and parental monitoring significantly related to last 30-day cannabis use. Higher levels of parental monitoring at lower levels of depressed affect related to lower likelihood of cannabis use. Female students had greater likelihood of endorsing cannabis use at higher levels of depressed affect. In the linear portion of the censor-inflated regression models, sex and level of parental monitoring significantly related to cannabis use frequency. Male students endorsed more frequent cannabis use while higher levels of parental monitoring related to lower frequency of use. DISCUSSION AND CONCLUSIONS: Parental monitoring may dampen the effect of depressed affect on cannabis use among AI youth on reservations. SCIENTIFIC SIGNIFICANCE: Future interventions should foster skill-building prevention efforts directed at coping with depression, along with parental training for effective monitoring. Special attention to AI female adolescents may be indicated.

Um estudo sobre o paradigma proibicionista e a (des)criminalização da maconha no Brasil / A study of the prohibitionist paradigm and the (de)criminalization of marihuana in Brasil / Un estudio sobre el paradigma prohibicionista y la (des)criminalización de la marihuana em Brasil

A maconha atualmente figura entre as substâncias consideradas ilícitas no Brasil. No entanto, nem sempre foi assim. O processo histórico que culminou com a proibição da maconha no Brasil é datado do início do século XX, perpassado por concepções eugenistas e higienistas que consolidaria o paradigma proibicionista.Todavia, ainda que paulatinamente, o proibicionismo vem sendo questionado em âmbito internacional e já há registros de outros modelos de relação de Estados com as drogas e dos indivíduos com as substâncias psicoativas. Sendo assim, o presente artigo, através da realização de entrevistas semiestruturadas, buscou identificar as diferentes maneiras pelas quais a proibição da maconha exerce seus efeitos nas subjetividades de indivíduos militantes, usuários ou não da planta. Dessa maneira, pretende-se demostrar a possibilidade de se pensar novas formas de se relacionar com a maconha, tanto em âmbito individual quanto em âmbito social, e ampliar o conhecimento da população acerca dos efeitos da proibição. (AU)

Marijuana currently ranks among the substances considered illegal in Brazil. However, it was not always like this. The historical process that culminated inthe prohibition of marijuana in Brazil is dated to the beginning of the 20th century, when eugenicist and hygienist ideas helped to consolidated the prohibitionist paradigm. However, even if gradually, prohibitionism has been questioned at the international level and there are already records of other models of relationship between States and drugs and between individuals and psychoactive substances. Therefore, this article, through semi-structured interviews, sought to identify the different ways in which the prohibition of marijuana exerts its effects on the subjectivities of individuals, users or not users of the plant. In this way, it is intended to demonstrate the possibility of thinking about new ways of relating to marijuana, both individually and socially and to broaden the population's knowledge about the effects of the ban. (AU)

La marihuana, en la actualidad, se encuentra como las substancias ilegales en Brasil. Pero no siempre fue así. El proceso histórico que culminó con la prohibición de marihuana en Brasil data del principio del siglo XX, influenciado por concepciones eugénicas e higienistas que consolidarían el paradigma prohibicionista. Aunque gradualmente, el prohibicionismo ha sido cuestionado y ya existen otros modos de relación entre los Estados con las drogas y también de las personas con las substancias. Por ello, este artículo, a través de entrevistas, buscó identificar las diferentes formas que la prohibición de la marihuana ejerce sus efectos sobre la subjetividad. Por lo tanto, tiene la intención de demonstrar la posibilidad de pensar en diferentes modos de relacionarse con la marihuana, tanto individual como socialmente, así como aumentar el conocimiento acerca de los efectos de la criminalización. (AU)

Determinants of alcohol consumption and marijuana use among young adults in the Republic of Palau.

BACKGROUND: This study aimed to describe the status of alcohol consumption and drug use among young adults as well as their determinants. METHODS: We conducted a cross-sectional study of 356 young adults (aged 18 to 24 years) living in Palau in 2013. The prevalence of self-reported alcohol and marijuana usage were compared within and between sexes, age groups, ethnicities, and education levels. RESULTS: The proportion of current drinking was higher in people aged 21-24 than in those aged 18-20 (73.2% vs. 60.9%, p = 0.09 in men and 48.3% vs. 30.0%, p = 0.02 in women), while that of marijuana use did not differ between the age groups. The proportions of current drinking and marijuana use were higher in Palauan than in other ethnicities (current drinking: 70.6% vs. 40.6%, p = 0.005 in men and 38.8% vs. 16.6%, p = 0.04 in women; lifetime marijuana use: 80.0% vs. 52.9%, p = 0.02 in men and 56.1% vs. 30.6%, p = 0.09 in women). The proportion of frequent (3 times or more) marijuana users was higher for the lower educated than for the higher educated (62.5% vs. 32.1%, p < 0.001 in men and 33.9% vs. 24.4%, p = 0.12 in women). CONCLUSIONS: Sex, age, ethnicity, and education were significant determinants of alcohol and marijuana use.

Three As of American Indian adolescent marijuana use: Availability, acceptability, and approval.

BACKGROUND: American Indian (AI) adolescents report high rates of marijuana use and related consequences and availability of marijuana has a robust relationship with marijuana use. The purpose of the present study was to examine the role of perceptions of approval (i.e., injunctive norms), and acceptability (i.e., descriptive norms and perceived harm) in the relationship between marijuana availability and marijuana use. METHODS: Data collected from 2009 to 2013 included 3498 AI 7th-12th graders residing on or near a reservation (47.8 % female). Multilevel mediation analyses were conducted using the MLmed macro in IBM SPSS v26.0 to account for the nesting of data within schools. RESULTS: The associations between marijuana availability and perceived risks (b=-.38, p < .001), descriptive norms (b = .80, p < .001), and injunctive norms related to marijuana use (b=-.24, p < .001), were significant. The associations between perceived risks (b=-.27, p < .001), descriptive norms (b = .14, p < .001), and injunctive norms (b=-.18, p < .001) and marijuana use were also significant. The indirect effects of marijuana availability on marijuana use through the pathways of perceived risks (b = .10, p < .001, 95 %CI[.08, .12]), descriptive norms (b = .11, p < .001, 95 %CI[.09, .14]), and injunctive norms related to marijuana use (b = .04, p < .001, 95 %CI[.03, .06]) were significant. The direct effect linking marijuana availability to marijuana use remained significant (b = .28, p < .001) but decreased by 37.8 %. when controlling for perceived risks, descriptive norms, and injunctive norms related to marijuana use. CONCLUSIONS: Interventions aiming to reduce AI adolescent marijuana use should focus on availability and may also be well served by targeting descriptive and injunctive norms, as well as perceived risks of marijuana use.

Racial/Ethnic Differences in Age at Menarche and Lifetime Nonmedical Marijuana Use: Results from the NHANES 2005-2016.

Early age at menarche has been linked to many adverse health outcomes among women, including substance use. However, little is known on the association between age at menarche and nonmedical use of marijuana, and no study has assessed the potential racial/ethnic differences. In this study, the 2005-2016 National Health and Nutrition Examination Survey data were used to investigate the association between age at menarche and the risk of lifetime nonmedical use of marijuana. Logistic regression models were used to examine such association adjusting for sociodemographic factors. Interactions between age at menarche and race/ethnicity were also assessed. Among the 10,302 women included, 53.9% had lifetime nonmedical use of marijuana. The regression model shows that women with early menarche had 1.26 (95% CI 1.09, 1.45) times the odds of having lifetime nonmedical use of marijuana compared with women with normal age at menarche. When assessing the association by race/ethnicity, marginally positive associations were observed for both the early and late menarche groups among non-Hispanic White women. However, among women with race/ethnicity other than non-Hispanic White, early menarche is significantly associated with increased risks of lifetime nonmedical marijuana use, while late menarche is significantly associated with decreased risks. This study suggests that early menarche may be a risk factor of lifetime nonmedical use of marijuana, and racial/ethnic differences may exist in the association. Future studies are warranted to examine and confirm these findings.

Determinants of alcohol consumption and marijuana use among young adults in the Republic of Palau

BACKGROUND@#This study aimed to describe the status of alcohol consumption and drug use among young adults as well as their determinants.@*METHODS@#We conducted a cross-sectional study of 356 young adults (aged 18 to 24 years) living in Palau in 2013. The prevalence of self-reported alcohol and marijuana usage were compared within and between sexes, age groups, ethnicities, and education levels.@*RESULTS@#The proportion of current drinking was higher in people aged 21-24 than in those aged 18-20 (73.2% vs. 60.9%, p = 0.09 in men and 48.3% vs. 30.0%, p = 0.02 in women), while that of marijuana use did not differ between the age groups. The proportions of current drinking and marijuana use were higher in Palauan than in other ethnicities (current drinking: 70.6% vs. 40.6%, p = 0.005 in men and 38.8% vs. 16.6%, p = 0.04 in women; lifetime marijuana use: 80.0% vs. 52.9%, p = 0.02 in men and 56.1% vs. 30.6%, p = 0.09 in women). The proportion of frequent (3 times or more) marijuana users was higher for the lower educated than for the higher educated (62.5% vs. 32.1%, p < 0.001 in men and 33.9% vs. 24.4%, p = 0.12 in women).@*CONCLUSIONS@#Sex, age, ethnicity, and education were significant determinants of alcohol and marijuana use.

Racial and gender inequities in the implementation of a cannabis criminal justice diversion program in a large and diverse metropolitan county of the USA.

BACKGROUND: Diversion programs are considered alternatives to the arrest and incarceration of non-violent drug offenders, including those found in possession of smaller amounts of cannabis in states with prohibitive laws. Despite the progressive nature of such programs, the inability to complete diversion program requirements can often result in greater involvement with the criminal justice system than traditional case adjudication. Few studies have evaluated racial group differences in cannabis diversion program completion. METHODS: The current study examined a sample of 8323 adult participants in Harris County, Texas' Marijuana Misdemeanor Diversion Program (MMDP) between March 2017 and July 2019. Gender, age, and race/ethnicity were examined as predictors of program completion and time to completion using Chi square, Kruskal Wallis tests, and Cox proportional hazard regression models. RESULTS: Both males and African Americans were over-represented (80 % and 50 %, respectively) among participants of Harris County's MMDP. African American (HR = 0.782, 95 % CI [.735-.832], p < .001) and Latino American MMDP participants (HR = .822, 95 % CI [.720-.937], p = .003) had significantly lower odds of MMDP completion and a longer interval to program completion as compared to non-Latino White participants. CONCLUSIONS: The current study identified racial/ethnic and gender disparities in a large county's cannabis diversion program. These findings may be related to law enforcement disparities which disproportionately target males and people of color. Findings may serve to inform the continued reform of the criminal justice system, particularly laws relating to cannabis.

Authoritative Parenting Behaviors and Marijuana Use Based on Age Among a National Sample of Hispanic Adolescents.

Although numerous prevention efforts have been implemented, marijuana remains the most commonly used illicit substance among Hispanic adolescents nationwide. We sought to determine the influence authoritative parenting behaviors have on lifetime, past year, and past month marijuana use among Hispanic adolescents overall, and then based on age (i.e., 12-13, 14-15, and 16-17 years). We conducted a secondary analysis of the 2012 National Survey on Drug Use and Health (N = 3457). We performed a series of logistic regression analyses. Nearly one-fifth (19.5%) of Hispanic participants reported lifetime marijuana use, 14.5% reported past year use, and 7.5% reported past month use. Results indicated that Hispanic adolescents who are at significantly increased risk for reporting lifetime, past year, and past month marijuana use, were those who reported that their parents seldom or never performed the following behaviors: (1) checked if their homework was done, (2) helped them with their homework, (3) limited the amount of TV they watched, (4) told them they did a good job, and (5) told them they were proud of them. There were no relationships between adolescents' lifetime, past year, or past month marijuana use and whether their parents made their youth do chores or limited their time out on a school night. Regarding age, while results indicated that most authoritative parenting behaviors have a significant effect against marijuana use, the protective effect diminished with age, with the exception of the relationship between adolescents' past month marijuana use and whether their parents checked to see if their homework was done. Substance use prevention programs for this population should start in early adolescence and involve and educate parents on adopting authoritative parenting behaviors.

Public and private religious involvement and initiation of alcohol, cigarette, and marijuana use in Black and White adolescent girls.

PURPOSE: This longitudinal study aimed to identify variation by race in the associations between religious involvement and initiation of alcohol, cigarette, and marijuana use, including distinctions by substance or type of religious involvement, in Black and White adolescent girls. METHODS: Data were drawn from interviews conducted at ages 11 through 17 with 2172 Pittsburgh Girls Study participants (56.8% Black; 43.2% White). Two indicators of public religious involvement, religious service attendance and participation in other religious activities, and two indicators of private religious involvement, prayer, and importance of religion were queried. A series of Cox proportional hazards regression analyses were conducted to identify independent effects of religious involvement indicators on initiation of each substance. RESULTS: Prior to adjusting for socioenvironmental and psychosocial factors (e.g., parental monitoring), importance of religion predicted initiation of alcohol use across race and cigarette and marijuana use in White but not Black girls. Participation in other religious activities also predicted marijuana use initiation only in White girls. In adjusted models, importance of religion remained significant for cigarette use initiation in White girls (hazard ratio [HR] = 0.68, 95% confidence intervals [CI]: 0.53-0.88) and participation in other religious activities remained significant for marijuana use initiation in White girls (HR = 0.63, CI: 0.47-0.83). CONCLUSIONS: The protective effects of religious involvement against cigarette and marijuana use initiation are more robust for White than Black adolescent girls and overall relatively weak for alcohol use initiation. Furthermore, importance placed on religion may be a better indicator than religious service attendance of risk for adolescent substance use initiation.

Marijuana risk perceptions are associated with past-month marijuana use among Black first-year college students at a historically Black university.

To examine the relationship between marijuana risk perceptions and marijuana use, and assess the potential moderating role of stress among Black students from a historically Black university, a convenience sample of students (n = 213) was surveyed. The majority (87.9%) of the sample was Black and 52% were female. Over a third (35.1%) reported past 30-day marijuana use, and a majority (58.4%) reported no or slight risk from using marijuana once or twice weekly. Higher marijuana risk perceptions were associated with lower odds of marijuana use (OR = .45, 95% CI [0.32, 0.64]). No significant relationship between stress and marijuana use was found. Perception of marijuana risk warrants further examination as a predictor of marijuana use.

Modeling Heterogeneous Peer Assortment Effects Using Finite Mixture Exponential Random Graph Models.

This article develops a class of models called sender/receiver finite mixture exponential random graph models (SRFM-ERGMs). This class of models extends the existing exponential random graph modeling framework to allow analysts to model unobserved heterogeneity in the effects of nodal covariates and network features without a block structure. An empirical example regarding substance use among adolescents is presented. Simulations across a variety of conditions are used to evaluate the performance of this technique. We conclude that unobserved heterogeneity in effects of nodal covariates can be a major cause of misfit in network models, and the SRFM-ERGM approach can alleviate this misfit. Implications for the analysis of social networks in psychological science are discussed.

Substance Use Outcomes for Hispanic Emerging Adults Exposed to Incarceration of a Household Member during Childhood.

This study investigates whether Hispanic emerging adults exposed to household incarceration before age 18 report higher rates of past 30-day cigarette, alcohol, binge drinking, marijuana use, and negative substance use consequences, relative to participants not exposed to incarceration of a household member. Respondents were matched on key characteristics to create balanced groups of exposed and nonexposed respondents. Negative binomial regression models assessed primary research questions. There were significant long-term associations between household incarceration and the frequency of past 30-day binge drinking, marijuana use, and number of negative substance use consequences. Policies and health programs addressing household incarceration may be a promising prevention approach to reduce negative substance use outcomes among Hispanic emerging adults.

Use of E-Cigarettes for Nicotine, Marijuana, and Just Flavoring Among U.S. Youth.

INTRODUCTION: E-cigarette use is gaining popularity among youth, but knowledge on patterns of youth vaping different substances is limited. This study examines risk factors associated with past-30-day self-reported vaping of nicotine, marijuana, and just flavoring among youth and the patterns (single, dual, and poly) of substances youth reported in their e-cigarettes. METHODS: The 2017 Monitoring the Future survey was analyzed. Weighted estimates of substances that youth vaped were calculated, and multivariable logistic regressions were performed to examine risk factors associated with youth vaping these substances. Analyses were conducted in 2019. RESULTS: Overall (n=14,560), 8.0% of participants reported currently vaping just flavoring, followed by 7.4% vaping nicotine and 3.6% vaping marijuana. Youth who were in 12th and 10th grade (versus 8th grade), male (versus female), current smokers (versus noncurrent smokers), and current marijuana users (versus noncurrent users) had increased risk of vaping nicotine, marijuana, and just flavoring. Black non-Hispanics were less likely than white non-Hispanics to report currently vaping. Among students who reported e-cigarette use in the last 30 days (n=1,685), only 24.9% reported vaping just flavoring only, and a majority (75.1%) reported vaping nicotine, marijuana, or multiple substances. Higher (versus lower) grade or increasing cigarette smoking intensity was associated with a higher proportion of students reporting vaping nicotine only and a lower proportion of students reporting vaping just flavoring only. CONCLUSIONS: Youth e-cigarette use reveals a complex pattern, and youth reported vaping substances potentially addictive beyond just flavoring. Strategies and interventions to reduce youth e-cigarette use are needed.

The prevalence of distress, depression, anxiety, and substance use issues among Indigenous post-secondary students in Canada.

This study aimed to estimate the prevalence of mental illness and substance use among Indigenous students attending Canadian post-secondary institutions. We obtained data from the National College Health Assessment - American College Health Association Spring 2013 survey, which includes 34,039 participants in 32 post-secondary institutions across Canada. We calculated prevalence estimates with 95% confidence intervals (CI). We compared Indigenous and non-Indigenous students using age- and sex-adjusted prevalence ratios (PR) obtained from Poisson regression models. Of the total sample, 1,110 (3.3%) post-secondary students self-identified as Indigenous. Within the past 12 months, Indigenous students had higher odds of intentionally injuring themselves (PR = 1.53, 95% CI = 1.27-1.84), seriously considering suicide (PR = 1.32, 95% CI = 1.12-1.56), attempting suicide (PR = 1.74, 95% CI = 1.16-2.62), or having been diagnosed with depression (PR = 1.26, 95% CI = 1.08-1.47) or anxiety (PR = 1.18, 95% CI = 1.02-1.35) when compared with non-Indigenous students. Indigenous students also had higher odds of having a lifetime diagnosis of depression (PR = 1.31, 95% CI = 1.17-1.47) when compared with non-Indigenous students. Indigenous students were more likely to report binging on alcohol (PR = 1.10, 95% CI = 1.02-1.19), using marijuana (PR = 1.21, 95% CI = 1.06-1.37), and using other recreational drugs (PR = 1.32, 95% CI = 1.06-1.63) compared to non-Indigenous students. This study demonstrates that Indigenous students at post-secondary institutions across Canada experience higher prevalence of mental health and related issues compared to the non-Indigenous student population. This information highlights the need to assess the utilization and ensure the appropriate provision of mental health and wellness resources to support Indigenous students attending post-secondary institutions.

Blunt use and menthol cigarette smoking: An examination of adult marijuana users.

INTRODUCTION: Use of menthol cigarettes remains highly prevalent among African American smokers and has increased among White and Hispanic/Latino smokers. Research is needed to examine if behavioral factors, such as marijuana use, are differentially associated with menthol cigarette use among racially/ethnically diverse samples of marijuana users. METHODS: Using data from the 2017 National Survey on Drug Use and Health, this study examined the association between past month marijuana (blunt versus non-blunt) and cigarette (non-menthol cigarette versus menthol cigarette versus no cigarette) use, as well as racial/ethnic differences in this relationship. RESULTS: Among all marijuana users (N = 5,137), 34.1% smoked blunts, 28.7% smoked non-menthol cigarettes and 18.0% smoked menthol cigarettes, with the highest rates of blunt (63.8%) and menthol cigarette (38.9%) use found among African American adults. Multinomial logistic regression analyses revealed a significant association between blunt use and non-menthol cigarette use (versus non-use) and menthol cigarette use (versus non-menthol cigarette and no cigarette use) among the full sample. When stratified by race/ethnicity, this finding was consistent for non-Hispanic White (n = 3,492) and partially consistent for Hispanic/Latino (n = 839) adults. However, among African American adults (n = 806), blunt use was not significantly associated with non-menthol cigarette use or menthol cigarette use. DISCUSSION: Blunt use is associated with increased odds of non-menthol and menthol cigarette use, but only among Hispanic/Latino and White adults. Examining racial/ethnic differences in the association between marijuana and tobacco use is important to understanding disparities and informing prevention and treatment interventions and drug policies.

Self-esteem, cultural identification, and substance use among American Indian youth.

OBJECTIVES: Determine potential mediating and moderating effects of self-esteem on the relationship between cultural identification and substance use among American Indian (AI) youth. METHODS: Anonymous surveys were administered to middle and high school AI students assessing levels of last month alcohol and marijuana use, cultural identification, and self-esteem. Structural equation modeling assessed potential mediating and moderating effects of self-esteem on the relationship between AI and white identification on alcohol and marijuana use. RESULTS: No mediating effects were found for middle school students. Among high school students, no mediating effects were found for alcohol. Among female high school students, a small mediating effect was found between AI identification and marijuana use, with AI identification protecting against use. Across all students, no moderating effects of self-esteem were found. CONCLUSIONS: The literature on cultural identification and substance use among minority youth is unclear. It was anticipated that consideration of self-esteem as a potential mediator or moderator might help clarify some of the confusion. However, no moderating effects were found and mediating effects were limited to female high school students for marijuana. Consideration should be given to assessing other measures of cultural identification and subscales of self-esteem to confirm that these findings are robust.

The Role of Acculturation and Alcohol Problems on Frequency of Cannabis Use Among Latinas at Risk of an Alcohol-Exposed Pregnancy.

Background: Along with alcohol, cannabis is one of the most commonly used substances among women of childbearing age. Recent studies indicate detrimental effects of prenatal cannabis use. Because many women use these substances before realizing they are pregnant, these serious health consequences for women and their offspring are of great concern. Despite the recent upsurge in cannabis use, little is known about individual and sociocultural factors that may contribute to risk of a cannabis-exposed pregnancy, particularly among Latinas of child-bearing age also at risk of an alcohol-exposed pregnancy (AEP). Objectives: Examine the relationships of acculturation, alcohol use, alcohol problems, and psychological distress with frequency of cannabis use among adult Latinas at risk of an AEP. Methods: The hypothesized model included 76 Latinas and was analyzed using path analysis. The study used baseline data from a randomized controlled trial of an intervention targeting risky drinking and tobacco use among women at risk of an AEP in primary care clinics. Results: Greater acculturation was associated with more frequent cannabis use and greater psychological distress. There was a positive indirect relationship between acculturation and alcohol use and alcohol problems through psychological distress. Greater alcohol problems were associated with more frequent cannabis use. Greater psychological distress and alcohol use were indirectly related to more frequent cannabis use through alcohol problems. Conclusions: Findings underscore the critical role of acculturation and alcohol-related problems in cannabis use frequency and have relevant implications for preventive efforts addressing cannabis use among Latinas at risk of an AEP.

Tobacco, alcohol and marijuana use among Indigenous youth attending off-reserve schools in Canada: cross-sectional results from the Canadian Student Tobacco, Alcohol and Drugs Survey. / Consommation de tabac, d'alcool et de cannabis chez les jeunes autochtones qui fréquentent des écoles hors réserve au Canada : résultats transversaux de l'Enquête canadienne sur le tabac, l'alcool et les drogues chez les élèves.

INTRODUCTION: Ongoing surveillance of youth substance use is essential to quantify harms and to identify populations at higher risk. In the Canadian context, historical and structural injustices make monitoring excess risk among Indigenous youth particularly important. This study updated national prevalence rates of tobacco, alcohol, and marijuana use among Indigenous and non-Indigenous students. METHODS: Differences in tobacco, alcohol, and marijuana use were examined, using logistic regression, among 1700 Indigenous and 22 800 non-Indigenous youth in Grades 9-12 who participated in the 2014/15 Canadian Student Tobacco, Alcohol and Drugs Survey. Differences by sex were also examined. Mean age of first alcohol and marijuana use was compared in the two populations using OLS regression. Results were compared to 2008/09 data. RESULTS: While smoking, alcohol, and marijuana rates have decreased compared to 2008/09 in both populations, the gap between the populations has mostly not. In 2014/15, Indigenous youth had higher odds of smoking (odds ratio [OR]: 5.26; 95% confidence interval [CI]: 3.54-7.81) and past-year drinking (OR: 1.43; 95% CI: 1.16- 1.76) than non-Indigenous youth. More Indigenous than non-Indigenous youth attempted quitting smoking. Non-Indigenous males were less likely to have had at least one drink in the past-year compared to non-Indigenous females. Indigenous males and females had higher odds of past-year marijuana use than non-Indigenous males (OR: 1.84; 95% CI: 1.32-2.56) and females (OR: 2.87; 95% CI: 2.15-3.84). Indigenous youth, especially males, drank alcohol and used marijuana at younger ages. CONCLUSION: Additional policies and programs are required to help Indigenous youth be successful in their attempts to quit smoking, and to address high rates of alcohol and marijuana use.

Sex Differences in the Association Between School Experiences and Marijuana Use Among African American Adolescents.

This study examined whether past month marijuana use among African American adolescents differed based on school experiences and individual feelings toward school. A secondary analysis of the 2012 National Survey on Drug Use and Health was conducted to answer research questions. Results from the multivariable logistic regression analyses revealed that female students at highest risk for recent use included those who held negative feelings toward school (OR 2.723, CI 1.683, 4.406, p < .001), felt courses were not interesting (OR 2.695, CI 1.513, 4.798, p < .01), and received mostly C's/D's/ F's in the last semester (OR 2.520, CI 1.614, 6.711,p < .001). For males, results indicated that male students at highest risk included those who held negative feelings toward school (OR 2.364, CI 1.365, 4.094, p < .01), felt things learned in school would not be important later in life (OR 3.470, CI 1.951, 6.173, p < .001), and received mostly C's/ D's/F's in the last semester (OR 2.733, CI 1.734, 4.309, p < .001). In the final model, of those who felt that most or all students in their grade used marijuana, males were 3 ½ times (OR 3.418, CI 1.741, 6.711, p < .001) and females were 8 times (OR 8.288, CI 3.526, 19.480, p < .001) more likely to have recently used marijuana. Such findings can be used by prevention specialists and health educators to develop and implement marijuana prevention programs and interventions specifically tailored to African American adolescents. Recommendations for future research are included.