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1.
Am J Otolaryngol ; 42(6): 103133, 2021.
Article En | MEDLINE | ID: mdl-34252712

INTRODUCTION: The infrahyoid myocutaneous flap (IHMCF) is an often-overlooked flap of the anterior neck used for reconstruction of oral cavity and laryngopharyngeal defects. The primary goal of this systematic review is to evaluate the postoperative outcomes and efficacy of this flap. METHODS: A comprehensive search of PubMed, Biological Abstracts, CINAHL Plus, and Web of Science was conducted. Two researchers independently scrutinized the studies to determine inclusions based on relevance, sample size, and English language publications. RESULTS: Twenty-eight studies containing 1027 IHMCF cases met the inclusion criteria. Primary outcomes included flap necrosis and postoperative functional outcomes. The rate of flap survival was 99%. Total skin necrosis and partial skin necrosis were minor complications that occurred in 2.5% and 5.8% of cases respectively. Poor speech and swallowing outcomes were reported in 6.4% and 6.5% of cases respectively. The included studies were predominantly retrospective. An average MINORS score of 9.6 suggests moderate bias among the studies. CONCLUSIONS: The IHMCF is both safe and effective for repairing medium sized mucosal lesions of the head and neck region in carefully selected patients. IHMCF use in oral cavity reconstruction is particularly appealing although functional outcomes remain difficult to statistically assess. Complications of IHMCFs are rare and often minor. To ensure the best outcome, pre-surgical planning needs to be conducted and all contraindications should be respected. Further large prospective multi-centered trials are needed for more accurate analysis.


Larynx/surgery , Mouth/surgery , Myocutaneous Flap , Otorhinolaryngologic Surgical Procedures/methods , Pharynx/surgery , Plastic Surgery Procedures/methods , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Myocutaneous Flap/adverse effects , Otorhinolaryngologic Surgical Procedures/adverse effects , Patient Care Planning , Pharynx/immunology , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Prospective Studies , Plastic Surgery Procedures/adverse effects , Retrospective Studies , Treatment Outcome , Young Adult
2.
Eur J Surg Oncol ; 47(4): 858-865, 2021 04.
Article En | MEDLINE | ID: mdl-33008672

INTRODUCTION: After extensive pelvic surgery for cancer two flap types are used at Skåne University Hospital (SUS), Sweden for perineal reconstruction: vertical rectus abdominis myocutaneous flap and gluteal flap with or without vaginal reconstruction. The objective was to study the long-term outcomes in patients treated for advanced pelvic cancer receiving a flap. METHOD: Patients with pelvic cancer subjected to surgery including perineal reconstruction between January 2010 and August 2016 at SUS were included retrospectively. Participating patients were scheduled for an out-patient visit. Questionnaires addressing quality of life, (QLQ-C30 and EQ-5D) and sexual function (FSFI and IIEF) were filled in. Sensitivity test, using monofilaments on the gluteal/posterior thigh area, neovaginal measurements using silicon gauges and muscular functionality tests (timed stands test and stairs test) were performed. RESULTS: Thirty-six (24 women, 12 males) out of 71 invited patients conceded participation. Patients scored a median of 85/100 regarding global health using EQ-5D. All women reported sexual dysfunction and 75% (9/12) of men reported severe erectile dysfunction. Neovaginal measurements showed adequate reconstructions. Sensitivity test implied decreased sensitivity on the operated side compared to the unoperated side in patients with gluteal flap. Both physical tests demonstrated adequate muscular functionality in everyday life activities after reconstructions using gluteal flap. CONCLUSION: This long-term follow up after extensive surgery treating pelvic cancer with perineal flap reconstruction implies high quality of life, good muscular functionality and adequate neovaginal measurements. However sexual function is impaired among both sexes and sensitivity in the surgical area of the gluteal flap is decreased.


Anus Neoplasms/surgery , Myocutaneous Flap , Perineum/surgery , Plastic Surgery Procedures/methods , Rectal Neoplasms/surgery , Sexual Dysfunction, Physiological/etiology , Sexuality , Adult , Aged , Aged, 80 and over , Buttocks/surgery , Erectile Dysfunction/etiology , Female , Follow-Up Studies , Humans , Lower Extremity/physiopathology , Male , Middle Aged , Muscle Strength , Myocutaneous Flap/adverse effects , Organ Size , Physical Functional Performance , Postoperative Complications/etiology , Quality of Life , Plastic Surgery Procedures/adverse effects , Rectus Abdominis/surgery , Retrospective Studies , Sexual Health , Surgically-Created Structures/pathology , Surveys and Questionnaires , Vagina/pathology
3.
World J Surg ; 45(1): 132-140, 2021 Jan.
Article En | MEDLINE | ID: mdl-32995931

BACKGROUND: Management of donor site closure after harvesting a vertical rectus abdominis myocutaneous (VRAM) flap is discussed heterogeneously in the literature. We aim to analyze the postoperative complications of the donor site depending on the closure technique. METHODS: During a 12-year period (2003-2015), 192 patients in our department received transpelvic VRAM flap reconstruction. Prospectively collected data were analyzed retrospectively. RESULTS: 182 patients received a VRAM flap reconstruction for malignant, 10 patients for benign disease. The median age of patients was 62 years. 117 patients (61%) received a reconstruction of donor site by Vypro® mesh, 46 patients (24%) by Vicryl® mesh, 23 patients (12%) by direct closure and 6 patients (3%) by combination of different meshes. 32 patients (17%) developed in total 34 postoperative complications at the donor site. 22 complications (11%) were treated conservatively, 12 (6%) surgically. 17 patients (9%) developed incisional hernia during follow-up, with highest incidence in the Vicryl® group (n = 8; 17%) and lowest in the Vypro® group (n = 7; 6%). Postoperative parastomal hernias were found in 30 patients (16%) including three patients with simultaneous hernia around an urostomy and a colostomy. The highest incidence of parastomal hernia was found in patients receiving primary closure of the donor site (n = 6; 26%), the lowest incidence in the Vypro® group (n = 16; 14%). CONCLUSION: The use of Vypro® mesh for donor site closure appears to be associated with a low postoperative incidence of complications and can therefore be recommended as a preferred technique.


Myocutaneous Flap , Plastic Surgery Procedures , Rectus Abdominis/transplantation , Transplant Donor Site/surgery , Adult , Aged , Aged, 80 and over , Female , Groin/surgery , Hernia, Abdominal/epidemiology , Hernia, Abdominal/etiology , Humans , Male , Middle Aged , Morbidity , Myocutaneous Flap/adverse effects , Perineum/surgery , Postoperative Complications/etiology , Postoperative Complications/surgery , Plastic Surgery Procedures/adverse effects , Plastic Surgery Procedures/methods , Retrospective Studies , Surgical Mesh/adverse effects , Vagina/surgery
4.
Khirurgiia (Mosk) ; (8): 29-34, 2020.
Article Ru | MEDLINE | ID: mdl-32869612

OBJECTIVE: To report our own experience of one-stage surgical treatment of irradiation-induced osteomyelitis as a complication of radiotherapy for breast cancer (BC). MATERIAL AND METHODS: The study included 25 patients with irradiation-induced chest osteomyelitis after previous radiotherapy for breast cancer. All patients were examined according to the same protocol. One-stage surgery with full-thickness resection of affected tissues and plastic closure of the wound was performed depending on localization of lesion and availability of plastic material. RESULTS: Follow-up period ranged from 18 to 110 months (median 48 (19; 52) months). Complications were assessed according to Clavien-Dindo classification. Complications followed by antibacterial therapy and/or local treatment were observed in 8 (32%) out of 25 patients (95% CI 11.5-43.4). Marginal necrosis of musculoskeletal flap was registered in 4 (16%) patients. One (4%) patient required redo thoracomyoplasty after excision of necrotic tissues of musculocutaneous flap due to extensive tissue defect. Total necrosis of musculocutaneous flap was not noted. There were no fatal outcomes. Mean length of hospital-stay was 13 (10; 27) days in the group of musculocutaneous flap from latissimus dorsi muscle and 11 days (7; 24) in the group of rectus abdominis muscle. Good and satisfactory treatment outcomes after one-stage surgical treatment were achieved in 24 (96%) out of 25 patients (95% CI: 75-97.8). CONCLUSION: Irradiation-induced chest osteomyelitis is still actual problem despite an improvement of modern medical equipment and accumulation of experience in radiotherapy. Surgery is preferable method of treatment. Comprehensive examination including contrast-enhanced chest CT with 3D reconstruction and Doppler ultrasound of vascular pedicle is valuable to determine type of resection and plastic technique. Simultaneous approach with resection and plastic closure of the wound is preferred for irradiation-induced chest osteomyelitis if sufficient amount of plastic material is available and contraindications for reconstructive surgery are absent.


Breast Neoplasms/radiotherapy , Myocutaneous Flap , Osteomyelitis/surgery , Plastic Surgery Procedures/methods , Radiotherapy/adverse effects , Thoracic Wall/surgery , Humans , Muscle, Skeletal/transplantation , Myocutaneous Flap/adverse effects , Osteomyelitis/etiology , Reoperation , Thoracic Wall/radiation effects , Thoracoplasty/methods , Treatment Outcome
5.
Plast Reconstr Surg ; 145(3): 475e-480e, 2020 03.
Article En | MEDLINE | ID: mdl-32097290

BACKGROUND: Patient-reported lower satisfaction with the abdomen preoperatively is a strong predictor of undergoing DIEP flap surgery. The authors evaluated physical well-being of the abdomen before and after flap-based breast reconstruction to determine potential predictors for decreased postoperative abdominal well-being. METHODS: The authors retrospectively analyzed an institutional breast reconstruction registry, selecting patients who underwent abdominally based autologous flap breast reconstruction from 2010 to 2015. The authors' primary outcome was the Physical Well-being of the Abdomen domain from the BREAST-Q, measured preoperatively and at 6- and 12-month follow-up visits after final reconstruction. The authors classified two patient groups: those who experienced a clinically important worsening of Physical Well-being of the Abdomen score and those who did not. The authors used the chi-square test, t test, and Wilcoxon rank sum test, and multivariable logistic regression to identify potential predictors. RESULTS: Of 142 women identified, 74 (52 percent) experienced clinically important worsening of physical well-being of the abdomen, whereas 68 (48 percent) did not. The first group experienced a 25-point (95 percent CI, 22 to 28) decrease and the latter an 8-point (95 percent CI, 5 to 10) decrease in score compared to baseline. Multivariable analysis showed an association between higher baseline score and race, with higher odds of decreased score at the 12-month follow-up. A higher baseline RAND-36 general health score, bilateral reconstruction, and a lower body mass index demonstrated a trend for clinically important worsening of physical well-being of the abdomen. CONCLUSIONS: More than half of flap-based breast reconstruction patients experienced clinically important worsening of abdominal well-being after final breast reconstruction. Clinicians may use these findings to identify patients at higher risk of worsened postoperative abdominal well-being. CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, III.


Abdominal Wall/surgery , Mammaplasty/adverse effects , Myocutaneous Flap/adverse effects , Perforator Flap/adverse effects , Postoperative Complications/epidemiology , Adult , Breast Neoplasms/surgery , Female , Follow-Up Studies , Humans , Mammaplasty/methods , Mastectomy/adverse effects , Middle Aged , Myocutaneous Flap/transplantation , Patient Reported Outcome Measures , Patient Satisfaction , Perforator Flap/transplantation , Postoperative Complications/etiology , Registries/statistics & numerical data , Retrospective Studies , Risk Assessment , Risk Factors , Transplantation, Autologous/adverse effects , Transplantation, Autologous/methods , Treatment Outcome
6.
Plast Reconstr Surg ; 145(3): 491e-498e, 2020 03.
Article En | MEDLINE | ID: mdl-32097296

BACKGROUND: After breast reconstruction, nipple position and other long-term changes in the reconstructed breast relative to the contralateral breast remain poorly understood. In this prospective cohort study, the authors performed serial nipple position measurements over 5 years in patients who had undergone breast reconstruction with a transverse rectus abdominis musculocutaneous (TRAM) flap. The effects of adjuvant radiotherapy on nipple position over time were also investigated. METHODS: The authors studied 150 patients who had undergone nipple-sparing mastectomy, using radial incision followed by immediate unilateral pedicled TRAM flap breast reconstruction. Measurements of sternal notch-to-nipple, midline-to-nipple, and inframammary fold-to-nipple distances were performed 1 day before reconstruction and 6, 12, 36, and 60 months after surgery, on patients' reconstructed and nonoperated breasts. RESULTS: The average sternal notch-to-nipple distance increased in both reconstructed and nonoperated breasts at every follow-up visit, with an average difference of 0.393 cm at the 60-month visit (p < 0.0001). Comparing the pattern of distance change, reconstructed breasts tend to change more slowly than nonoperated breasts until 36 months postoperatively. In irradiated breasts, the sternal notch-to-nipple distance was significantly smaller than in nonirradiated breasts, and nipple position changed minimally between 1 and 3 years after surgery. CONCLUSIONS: Nipple position in TRAM flap-reconstructed breasts changed over time compared with that in nonoperated breasts, especially along the vertical axis. The pattern of nipple position change in reconstructed breasts became similar to nonoperated breasts 3 years after surgery. In patients who had undergone adjuvant radiation therapy, nipple position remained consistent for 1 to 3 years. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.


Breast Neoplasms/therapy , Mammaplasty/adverse effects , Myocutaneous Flap/adverse effects , Nipples/anatomy & histology , Rectus Abdominis/transplantation , Adult , Aged , Female , Follow-Up Studies , Humans , Mammaplasty/methods , Mastectomy, Subcutaneous/adverse effects , Middle Aged , Myocutaneous Flap/transplantation , Nipples/radiation effects , Nipples/surgery , Prospective Studies , Radiotherapy, Adjuvant/adverse effects , Treatment Outcome
7.
Microsurgery ; 40(1): 38-43, 2020 Jan.
Article En | MEDLINE | ID: mdl-30793787

BACKGROUND: Identification and understanding of predictors for complications and aesthetic outcomes in free muscle-sparing transverse rectus abdominis myocutaneous (MS-TRAM) flap are essential for successful breast reconstruction. The purpose of this study was to investigate predictors for complications and aesthetic outcomes in patients who underwent autologous breast reconstruction with free MS-TRAM flaps. PATIENTS AND METHODS: Between March 2003 and September 2017, a total of 214 patients who underwent breast reconstruction with MS-TRAM flaps were included in this study. Mean age of the patients was 43.2 years (range, 28-61 years). Four outcome data, including operation time, hospital stay, aesthetic scores, and complications; and 12 patient data, including recipient vessel type, age, body mass index [BMI] > 25, smoking status, neoadjuvant chemotherapy, radiotherapy, nipple-sparing mastectomy, contralateral breast surgery, history of hypertension, diabetes mellitus, cardiac disease, and endocrine disease were collected. RESULTS: Five and 52 patients experienced major complications, including partial flap loss, and minor complications, respectively. In stepwise multiple logistic analysis, risk factors for complications were BMI > 25 (P < 0.001), smoking status (P = 0.012), and neoadjuvant radiotherapy (P = 0.002). BMI > 25 (P < 0.001), smoking status (P < 0.001), contralateral breast surgery (P < 0.001), and history of cardiac (P = 0.001) and endocrine disease (P = 0.003) were predictors for aesthetic outcome. CONCLUSION: Predictors for complications and aesthetic outcomes determined in this study may facilitate microsurgeons engaged in the assessment of patients needing free MS-TRAM flaps.


Mammaplasty/adverse effects , Myocutaneous Flap/adverse effects , Postoperative Complications/epidemiology , Adult , Aged , Body Mass Index , Esthetics , Female , Humans , Length of Stay , Mastectomy , Middle Aged , Operative Time , Rectus Abdominis , Retrospective Studies , Risk Factors
8.
Semin Thorac Cardiovasc Surg ; 32(2): 369-376, 2020.
Article En | MEDLINE | ID: mdl-31866574

Sternoclavicular joint (SCJ) infection is a rare disease and its management remains controversial. Our institution has adopted an aggressive surgical approach of radical SCJ resection combined with myocutaneous flap (MCF) closure whenever possible. We reviewed our experience with this approach in the management of this condition. From July 2004 to June 2018, 50 consecutive patients were treated surgically for SCJ infections. Patient demographics, imaging studies, microbiology, and operative variables were analyzed. All patients underwent ipsilateral SCJ resection. Wound closure was performed with primary pectoralis advancement MCF closure at the initial operation in 25 patients, delayed MCF closure following temporary wound vacuum therapy and redebridement in 19 patients, and definitive wound vacuum therapy (DWVT) in 6 patients. End points were recurrence of infection, perioperative morbidity, and mortality. Localized swelling (100%) and pain (100%) were the most common presenting symptoms. MSSA was isolated in 50% of tissue cultures. Comorbidities included tobacco smoking 52%, diabetes mellitus 50%, intravenous drug use 34%, poor dental hygiene 32%, and obesity 28%. We had no deaths within 90 days of operation. Complications; seroma in 1 patient (2%), chest wall hernia in 1 patient (2%), retained drains in 1 patient (2%), recurrent osteomyelitis infection in 3 patients (6%), and hematomas in 5 patients (10%). Patients treated with primary MCF closure at the initial operation had a 0% (0/25) rate of recurrence compared to 5.26% (1/19) in delayed MCF closure. Overall, there was only a 2.27% (1/44) recurrence of infection in primary and delayed MCF closure combined, compared to 33.33% (2/6) in patients treated with DWVT closure. SCJ infections require an aggressive approach. Wound closure with an MCF (primary or delayed) is associated with less recurrence of infections compared with DWVT closure. Radical resection of the entire SCJ with MCF (primary or delayed) should be considered the preferred management strategy in patients with SCJ infections.


Arthritis, Infectious/surgery , Myocutaneous Flap , Negative-Pressure Wound Therapy , Osteomyelitis/surgery , Sternoclavicular Joint/surgery , Adult , Aged , Arthritis, Infectious/diagnosis , Arthritis, Infectious/microbiology , Arthritis, Infectious/mortality , Databases, Factual , Female , Humans , Male , Middle Aged , Myocutaneous Flap/adverse effects , Negative-Pressure Wound Therapy/adverse effects , Negative-Pressure Wound Therapy/mortality , Osteomyelitis/diagnosis , Osteomyelitis/microbiology , Osteomyelitis/mortality , Recurrence , Retrospective Studies , Risk Assessment , Risk Factors , Sternoclavicular Joint/microbiology , Time Factors , Time-to-Treatment , Treatment Outcome
10.
Ann Plast Surg ; 83(6): e39-e42, 2019 12.
Article En | MEDLINE | ID: mdl-30882420

Reconstruction of intraoral defects is one of the main aspects of head and neck cancer treatment. Since the advent of microvascular surgery in this field, free flap tissue transfer has become a common procedure, and various flaps have been described for soft tissue reconstruction. The lateral upper arm free flap is one of the most frequently used flaps for intraoral defect coverage. This article describes ossification of the corresponding vascular pedicle after soft tissue transfer with the lateral upper arm free flap and microsurgical anastomosis in oral cancer treatment. Similar findings in the context of the lateral upper arm free flap have never been reported in the literature; however, it is important for surgeons to know that pedicle ossification can occur. This knowledge may be helpful to avoid erroneous diagnosis of the ossification as a sign of tumor relapse/recurrence as well as to anticipate potential difficulties in the surgical approach in cases requiring reentry of the reconstructed region, for example, in relapse/recurrence of head and neck cancer.


Mouth Neoplasms/surgery , Myocutaneous Flap/adverse effects , Neoplasm Recurrence, Local/surgery , Osteogenesis/physiology , Plastic Surgery Procedures/methods , Surgical Flaps/adverse effects , Arm/surgery , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/surgery , Cohort Studies , Female , Follow-Up Studies , Graft Rejection , Graft Survival , Head and Neck Neoplasms/pathology , Head and Neck Neoplasms/surgery , Humans , Male , Microsurgery/methods , Middle Aged , Mouth Neoplasms/pathology , Myocutaneous Flap/transplantation , Neoplasm Recurrence, Local/pathology , Retrospective Studies , Risk Assessment , Surgical Flaps/transplantation , Treatment Outcome
11.
J Int Med Res ; 47(1): 76-83, 2019 Jan.
Article En | MEDLINE | ID: mdl-30514138

OBJECTIVE: This study aimed to compare the results of the pectoralis major myocutaneous (PMM) flap in primary and salvage head and neck cancer surgery. METHODS: A total of 160 patients were enrolled in this study. The salvage group consisted of 30 patients who received immediate PMM flap surgery following free flap failure. In the primary group, the PMM flap was primarily chosen for 130 patients. Related information was collected and analysed. The University of Washington (UW)-Quality of Life questionnaire, version 4, was mailed to every patient. RESULTS: Partial necrosis was significantly lower in the primary group (n = 13, 10.0%) than in the salvage group (n = 7, 23.3%). Surgical site infection was found in 10 (7.8%) patients in the primary group and in six (20.0%) patients in the salvage group. The mean composite quality of life scores were 66.8 ± 20.5 and 66.2 ± 22.1 in the two groups, respectively. Differences in scores for domains of activity, mood, and anxiety were significant. Disease-specific survival and recurrence-free survival rates were not different between the two groups. CONCLUSION: PMM flap salvage reconstruction has a higher complication rate and poorer functional results, but similar survival prognosis, compared with primary surgery.


Head and Neck Neoplasms/surgery , Myocutaneous Flap/surgery , Necrosis/diagnosis , Pectoralis Muscles/surgery , Quality of Life/psychology , Surgical Wound Infection/diagnosis , Adult , Aged , Aged, 80 and over , Female , Head and Neck Neoplasms/mortality , Head and Neck Neoplasms/pathology , Head and Neck Neoplasms/psychology , Humans , Male , Middle Aged , Myocutaneous Flap/adverse effects , Myocutaneous Flap/transplantation , Necrosis/etiology , Necrosis/mortality , Necrosis/pathology , Plastic Surgery Procedures/methods , Salvage Therapy/methods , Surgical Wound Infection/etiology , Surgical Wound Infection/mortality , Surgical Wound Infection/pathology , Surveys and Questionnaires , Survival Analysis , Treatment Failure
12.
Plast Reconstr Surg ; 143(3): 667-677, 2019 03.
Article En | MEDLINE | ID: mdl-30589826

BACKGROUND: This study aimed to identify differences in patient-reported abdominal well-being, satisfaction, and quality of life in women with muscle-preserving free abdominal versus pedicle transverse rectus abdominis musculocutaneous (TRAM) flap for breast reconstruction. METHODS: Women with a history of breast cancer surgery were recruited from the Army of Women foundation to take the BREAST-Q and a background questionnaire. Descriptive statistics and regression analyses were used to compare abdominal physical well-being, breast satisfaction, chest physical, psychosocial well-being, and sexual well-being in women undergoing free versus pedicle TRAM flaps. RESULTS: Of 657 women, 273 (41 percent) underwent free flap surgery and 384 (58 percent) underwent pedicle TRAM flap surgery. Compared with unilateral pedicle TRAM flaps, those with unilateral free flaps scored an average of 9.5 points higher (95 percent CI, 5.4 to 13.6; p < 0.0001) and those with bilateral free flaps reported no difference in physical well-being of the abdomen. Compared with bilateral pedicle TRAM flaps, the following groups scored higher in physical well-being of the abdomen: unilateral free flaps, an average of 17.4 (95 percent CI, 11.5 to 23.3; p < 0.0001); bilateral free flaps, an average of 6.8 (95 percent CI, 0.3 to 13.3; p = 0.04); and unilateral pedicle TRAM flaps, an average of 7.9 (95 percent CI, 2.4 to 13.4; p = 0.005) higher. Women with bilateral pedicle flaps reported sexual well-being scores 7.4 (95 percent CI, 0.6 to 14.3; p = 0.03) and 6.8 (95 percent CI, 0.3 to 13.2; p = 0.04) points lower than those with unilateral free and unilateral pedicle flaps. CONCLUSIONS: Muscle-preserving techniques result in improved abdominal wall function and decreased morbidity compared with pedicle TRAM flap reconstruction. These data highlight the importance of offering patients the option of microsurgical techniques.


Free Tissue Flaps/transplantation , Mammaplasty/methods , Myocutaneous Flap/transplantation , Patient Reported Outcome Measures , Transplant Donor Site/physiopathology , Abdominal Wall/physiopathology , Abdominal Wall/surgery , Aged , Breast Neoplasms/surgery , Cohort Studies , Female , Free Tissue Flaps/adverse effects , Humans , Mammaplasty/adverse effects , Mastectomy/adverse effects , Microsurgery/adverse effects , Microsurgery/methods , Middle Aged , Myocutaneous Flap/adverse effects , Organ Sparing Treatments/adverse effects , Organ Sparing Treatments/methods , Patient Selection , Quality of Life , Rectus Abdominis/transplantation , Transplantation, Autologous/adverse effects , Transplantation, Autologous/methods
13.
Rev. bras. cir. plást ; 33(4): 595-598, out.-dez. 2018. ilus
Article Pt | LILACS | ID: biblio-980169

Úlceras de pressão são alterações da integridade da pele e tecidos subjacentes, causadas por pressão, mais usualmente sobre proeminências ósseas, especialmente em áreas desprovidas de sensibilidade, levando à necrose e ulceração. Dados da literatura internacional estimam que 3 a 14% dos pacientes hospitalizados desenvolvem úlceras de pressão. Descrevemos a correção simultânea de úlceras sacral e isquiática extensas em paciente paraplégico jovem utilizando retalho fasciomiocutâneo de glúteo máximo e de face posterior da coxa.


Pressure ulcers are alterations of the integrity of the skin and underlying tissues, caused by pressure, more commonly on bony prominences, especially in areas devoid of sensitivity, which lead to necrosis and ulceration. Data from the international literature estimate that 3­14% of hospitalized patients develop pressure ulcers. We herein describe the simultaneous correction of extensive sacral and ischial ulcers in a young paraplegic patient, using a gluteus maximus fasciomyocutaneous flap from the posterior aspect of the thigh.


Humans , Male , Adult , Paraplegia/surgery , Paraplegia/complications , Pressure Ulcer/surgery , Pressure Ulcer/complications , Myocutaneous Flap/surgery , Myocutaneous Flap/adverse effects , Necrosis/surgery , Risk Factors , Muscle Spasticity
14.
J Surg Res ; 229: 169-176, 2018 09.
Article En | MEDLINE | ID: mdl-29936986

BACKGROUND: Reliable detection of any circulatory issue threatening flap viability after free flap surgery is essential for prompt flap salvage. Currently, the gold standard of flap monitoring is clinical monitoring. However, this method presents logistical challenges to insufficient trained personnel. Auxiliary methods are becoming increasingly vital. MATERIALS AND METHODS: Twelve swine pedicle myocutaneous flaps were harvested and monitored using infrared cameras to investigate the developed monitoring parameters and vascular thrombosis in the free flap model. RESULTS: The mean flap surface temperature after vein or artery occlusion decreased significantly, but the differences were relatively small. As a result, the difference between recorded (flap surface temperature [Ts]) and predicted (estimated surface temperature [Tes]) flap surface temperature (ΔT = Ts- Tes) was used as the parameter for pedicle thrombosis. A ΔT of <0.86°C was used as a vascular occlusion criterion; the sensitivity and specificity of this parameter were 90% and 81%, respectively. The standard deviation of the surface temperature (SDT) was another indicator of vascular occlusion; the estimated sensitivity and specificity for vessel occlusion of SDT < 0.48°C were 84% and 73%, respectively. CONCLUSIONS: Infrared thermal imaging has the advantages of being noninvasive, contact-free, continuous, and able to detect the whole flap surface area. Two indicators, ΔT and SDT, can be used with high sensitivity and specificity for early prediction of flap pedicle thrombosis. Further human studies are necessary to validate clinical application of infrared thermal imaging.


Myocutaneous Flap/adverse effects , Thermography/methods , Thrombosis/diagnostic imaging , Animals , Body Temperature , Disease Models, Animal , Humans , Male , Models, Biological , Myocutaneous Flap/blood supply , Prognosis , Sensitivity and Specificity , Spectrophotometry, Infrared/instrumentation , Spectrophotometry, Infrared/methods , Swine , Thermography/instrumentation , Veins/diagnostic imaging
15.
J Surg Res ; 229: 200-207, 2018 09.
Article En | MEDLINE | ID: mdl-29936991

BACKGROUND: Hidradenitis suppurativa (HS) is a chronic debilitating cutaneous disorder. The recalcitrant nature of this disease may require surgery in severe cases. We aimed to delineate the types of operations performed, the risk factors associated with these operations, and the surgical services involved based on a national database. METHODS: Data were collected through the American College of Surgeons National Surgical Quality Improvement Program from 2011 to 2016. Current Procedural Terminology (CPT) and International Classification of Disease, Ninth Revision, (ICD-9) codes were used for data extraction and analysis as type of surgery and complication rates were extracted. RESULTS: There were 2594 patients diagnosed with HS: 1405 (54.2%) incision and drainage, 1017 (39.2%) debridement, 31 (1.2%) skin graft, and 141 (5.4%) flap reconstruction. There were significant differences in transfusion rates and operation time among the four procedures. Skin graft and flap reconstruction had the highest complications and longest operation time. Bleeding requiring preoperative transfusion and a number of comorbidities were significant risk factors for postoperative complications. Flap reconstructions by plastic surgeons compared to general surgeons had significantly shorter operation times (134.89 versus 209.82 min, P = 0.022) and lower transfusion rates (2.2% versus 12.8%, P = 0.024). CONCLUSIONS: The management of HS can be complex and may require a multidisciplinary approach. Bleeding requiring preoperative transfusion and other baseline comorbidities are independent risk factors that should be addressed when definitive surgical treatment of hidradenitis is planned. Appropriate surgical specialty involvement may better optimize the surgical outcomes for HS.


Dermatologic Surgical Procedures/trends , Hemorrhage/therapy , Hidradenitis Suppurativa/surgery , Postoperative Complications/epidemiology , Adult , Aged , Blood Transfusion/statistics & numerical data , Comorbidity , Databases, Factual/statistics & numerical data , Debridement/adverse effects , Debridement/methods , Debridement/statistics & numerical data , Debridement/trends , Dermatologic Surgical Procedures/adverse effects , Dermatologic Surgical Procedures/methods , Dermatologic Surgical Procedures/statistics & numerical data , Drainage/adverse effects , Drainage/methods , Drainage/statistics & numerical data , Drainage/trends , Female , Hemorrhage/epidemiology , Hidradenitis Suppurativa/epidemiology , Humans , Interdisciplinary Communication , Male , Middle Aged , Myocutaneous Flap/adverse effects , Myocutaneous Flap/statistics & numerical data , Myocutaneous Flap/transplantation , Myocutaneous Flap/trends , Operative Time , Postoperative Complications/etiology , Preoperative Care/statistics & numerical data , Risk Factors
16.
J Surg Res ; 228: 253-262, 2018 08.
Article En | MEDLINE | ID: mdl-29907219

BACKGROUND: Tissue necrosis caused by insufficient perfusion is a major complication in flap transfer. This study evaluated whether treatment with cilostazol or hydroalcoholic extract of seeds of Euterpe oleracea Mart. (açaí) protects the transverse rectus abdominis myocutaneous (TRAM) flap against ischemic damage in hamsters. MATERIALS AND METHODS: Fifty-four hamsters were divided into three oral treatment groups: placebo, açaí, or cilostazol. Caudally based, unipedicled TRAM flaps were raised, sutured back, classified into four vascular zones (I-IV), and evaluated for tissue viability, capillary blood flow (CBF), perfused vessel density (PVD), and microvascular flow index (MFI) by orthogonal polarization spectral imaging at three time points: immediately postoperatively (IPO), 24 h postoperatively (24hPO), and 7 d postoperatively (7POD). RESULTS: Comparing to placebo, açaí increased PVD at IPO and açaí and cilostazol increased CBF and PVD at 24hPO in zone I; cilostazol increased CBF, PVD, and MFI at IPO, and CBF at 24hPO in zone II; açaí and cilostazol increased CBF at all time points and PVD and MFI at IPO and 24hPO in zone III; cilostazol increased CBF at IPO and 7POD, açaí increased CBF at 7POD, and both increased PVD and MFI at all time points in zone IV; and açaí and cilostazol increased the percentage of viable area in zones III and IV. CONCLUSIONS: Açaí and cilostazol treatments had a protective effect against ischemic damage to TRAM flaps in hamsters, improving microvascular blood flow and increasing the survival of flap zones contralateral to the vascular pedicle (zones III and IV).


Cilostazol/pharmacology , Euterpe/chemistry , Microcirculation/drug effects , Myocutaneous Flap/adverse effects , Plant Extracts/pharmacology , Rectus Abdominis/pathology , Animals , Capillaries/drug effects , Cilostazol/therapeutic use , Cricetinae , Disease Models, Animal , Drug Evaluation, Preclinical , Graft Survival/drug effects , Humans , Ischemia/drug therapy , Ischemia/etiology , Ischemia/pathology , Male , Mesocricetus , Myocutaneous Flap/blood supply , Myocutaneous Flap/pathology , Necrosis/drug therapy , Necrosis/etiology , Necrosis/pathology , Plant Extracts/therapeutic use , Rectus Abdominis/drug effects , Rectus Abdominis/transplantation , Seeds/chemistry , Skin/blood supply , Skin/drug effects , Skin/pathology
17.
J Craniofac Surg ; 29(5): 1137-1142, 2018 Jul.
Article En | MEDLINE | ID: mdl-29750727

BACKGROUND: Adipofascial flaps (AFF) with acellular dermal matrix (ADM) have the potential to reconstruct neural tube defects without sacrificing muscle that may be critical for long-term function. Comparative studies between myocutaneous flap (MF) reconstruction, the accepted standard reconstructive technique, and AFF/ADM remain under-reported. The aim of this study was to evaluate the safety and efficacy of myelomeningocele reconstruction using muscle sparing AFF/ADM versus MF. METHODS: A retrospective comparison was conducted on consecutive myelomeningocele patients reconstructed with MF or AFF/ADM over an 84-month period. Data analyzed included: basic demographics, defect size, reconstructive technique, complications, and length of follow-up. A supplemental meta-analysis based on systematic review of literature was performed to compare alternative reconstructive options. RESULTS: Twelve patients were identified who met inclusion criteria. Median age, weight, and defect size at reconstruction in the AFF/ADM group (n = 6) was 37.5 weeks, 3.25 kg, and 20.0 cm, respectively, and in the MF group (n = 6) was 37 weeks, 3.6 kg, and 22.5 cm (P > 0.5). For the AFF/ADM versus MF groups, median follow-up was 33.8 versus 22.6 months, reoperation rate was 0% versus 17% (P = 1.0), and complex skin flap closure rate was 17% versus 100% (P = 0.015). No cerebrospinal fluid leaks or surgical site infections occurred in either group. Meta-analysis of the literature revealed no statistically significant difference in complications rates between muscle and nonmuscle flap reconstruction (P > 0.5); potential long-term sequelae of muscle flap harvest were not included. CONCLUSIONS: Muscle sparing AFF with ADM is a safe and effective surgical alternative to muscle flaps for lumbar myelomeningocele reconstruction.


Acellular Dermis , Fascia/transplantation , Meningomyelocele/surgery , Myocutaneous Flap/transplantation , Plastic Surgery Procedures/methods , Subcutaneous Fat/transplantation , Female , Follow-Up Studies , Humans , Infant , Lumbar Vertebrae , Male , Muscle, Skeletal/surgery , Myocutaneous Flap/adverse effects , Organ Sparing Treatments , Plastic Surgery Procedures/adverse effects , Reoperation , Retrospective Studies
18.
JAMA Dermatol ; 154(6): 708-711, 2018 06 01.
Article En | MEDLINE | ID: mdl-29799979

Importance: Forehead reconstruction after Mohs surgery has become a challenge for dermatology surgeons, and achieving an excellent cosmetic and functional result is imperative in this location. Objective: To highlight the utility of a frontalis myocutaneous transposition flap (FMTF) for forehead reconstruction after Mohs surgery. Design, Setting, and Participants: Surgical technique case series including 12 patients with large forehead defects recruited between January 2010 and June 2017 at the Dermatology Department of the University Clinic of Navarra, Spain. All patients underwent Mohs micrographic surgery for skin cancer (5 basal cell carcinomas, 4 melanomas, 2 squamous cell carcinomas, and 1 adnexal tumor) located on the forehead (8 paramedian, 2 midline, and 2 lateral subunits) resulting in defects ranging from 9 to 28 cm2 in size. Intervention: Mohs micrographic surgery followed by FMTF. Taking into account the defect's size and location, a lateral lobulated flap is designed with an inferior pedicle and incision lines are made vertically to the hairline containing part of the frontalis muscle or its fascia. The flap swings into the primary defect and direct closure of the donor site is achieved. Additional corrections for removing skin folds or a guitar-string suture can be made. Main Outcomes and Measures: Absence of acute complications and achievement of high aesthetic and functional goals in postoperative follow-up. Results: Satisfactory cosmetic and functional results were achieved for all 12 patients (7 men and 5 women; mean age, 62.7 years [range, 47-86 years]) and there were no postoperative complications. All the myocutaneous flaps survived without any acute complications, such as episodes of local bleeding, infection, flap margin necrosis, or congestion. Postoperative follow-up ranged from 6 months to 3 years. No patient needed scar revision. Six patients presented with paresthesia in areas of the forehead and scalp. Sensory recovery tended to improve over time, and paresthesia gradually decreased, disappearing in 5 of 6 cases after 12 months. In 3 patients there was a minimal hair transposition that required laser treatment. Conclusions and Relevance: The FMTF provides a simple method for 1-stage reconstruction of large forehead defects as an alternative to classic advancement flaps.


Forehead/surgery , Mohs Surgery/adverse effects , Myocutaneous Flap , Plastic Surgery Procedures/methods , Skin Neoplasms/surgery , Surgical Wound/surgery , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Myocutaneous Flap/adverse effects , Paresthesia/etiology , Plastic Surgery Procedures/adverse effects , Surgical Wound/etiology
19.
Rev. cuba. cir ; 57(1): 72-77, ene.-mar. 2018. ilus
Article Es | LILACS | ID: biblio-960349

Los defectos de pared abdominal son un desafío para los cirujanos plásticos. El sarcoma de partes blandas es muy recidivante y hay que hacer amplias exéresis con margen oncológico y como consecuencia quedan amplias zonas por reconstruir. El colgajo transverso de recto abdominal es una opción reconstructiva de esta región con buenos resultados estéticos y funcionales. El objetivo del trabajo es mostrar los resultados de la reconstrucción inmediata de la pared abdominal luego de una amplia exéresis oncológica. Se presenta una paciente femenina, mestiza, de 60 años, con diagnóstico de sarcoma de partes blandas, que abarcaba todo el hemiabdomen ínfero izquierdo hasta límites del reborde costal izquierdo, comprometía aponeurosis, el músculo recto izquierdo, y pequeña parte del peritoneo que se reparó. Se decidió una amplia exéresis y se planificó la reconstrucción con un colgajo miocutáneo transverso de recto del abdomen. Se utilizaron mallas de polipropileno. Se logró la reconstrucción inmediata del defecto oncológico con buenos resultados estéticos y funcionales(AU)


Abdominal wall defects are a challenge for plastic surgeons. Soft-tissue sarcoma is very recurrent and it is necessary to make extensive exeresis with oncological margin and, as a result, there are large areas to be reconstructed. The transverse rectus abdominis flap is a reconstructive option for this region and with good aesthetic and functional results. The objective of the work is to show the results of the immediate reconstruction of the abdominal wall after an extensive oncological exeresis. We present the case of a female patient, mestiza, aged 60 years, with a diagnosis of soft-tissue sarcoma, which encompassed all the left inferior hemiabdomen to the left costal margin limits, compromised the aponeurosis, the left rectus muscle, and a small part of the peritoneum that was repaired. A wide exeresis was decided and the reconstruction was planned with a transverse rectus abdominis myocutaneous flap. Polypropylene meshes were used. The immediate reconstruction of the oncological defect was achieved with good aesthetic and functional results(AU)


Humans , Female , Middle Aged , Soft Tissue Neoplasms/diagnosis , Surgical Mesh/statistics & numerical data , Abdominal Wall/surgery , Myocutaneous Flap/adverse effects
20.
Rev. cuba. cir ; 57(1): 72-77, ene.-mar. 2018. ilus
Article Es | CUMED | ID: cum-72076

Los defectos de pared abdominal son un desafío para los cirujanos plásticos. El sarcoma de partes blandas es muy recidivante y hay que hacer amplias exéresis con margen oncológico y como consecuencia quedan amplias zonas por reconstruir. El colgajo transverso de recto abdominal es una opción reconstructiva de esta región con buenos resultados estéticos y funcionales. El objetivo del trabajo es mostrar los resultados de la reconstrucción inmediata de la pared abdominal luego de una amplia exéresis oncológica. Se presenta una paciente femenina, mestiza, de 60 años, con diagnóstico de sarcoma de partes blandas, que abarcaba todo el hemiabdomen ínfero izquierdo hasta límites del reborde costal izquierdo, comprometía aponeurosis, el músculo recto izquierdo, y pequeña parte del peritoneo que se reparó. Se decidió una amplia exéresis y se planificó la reconstrucción con un colgajo miocutáneo transverso de recto del abdomen. Se utilizaron mallas de polipropileno. Se logró la reconstrucción inmediata del defecto oncológico con buenos resultados estéticos y funcionales(AU)


Abdominal wall defects are a challenge for plastic surgeons. Soft-tissue sarcoma is very recurrent and it is necessary to make extensive exeresis with oncological margin and, as a result, there are large areas to be reconstructed. The transverse rectus abdominis flap is a reconstructive option for this region and with good aesthetic and functional results. The objective of the work is to show the results of the immediate reconstruction of the abdominal wall after an extensive oncological exeresis. We present the case of a female patient, mestiza, aged 60 years, with a diagnosis of soft-tissue sarcoma, which encompassed all the left inferior hemiabdomen to the left costal margin limits, compromised the aponeurosis, the left rectus muscle, and a small part of the peritoneum that was repaired. A wide exeresis was decided and the reconstruction was planned with a transverse rectus abdominis myocutaneous flap. Polypropylene meshes were used. The immediate reconstruction of the oncological defect was achieved with good aesthetic and functional results(AU)


Humans , Female , Middle Aged , Soft Tissue Neoplasms/diagnosis , Surgical Mesh , Abdominal Wall/surgery , Myocutaneous Flap/adverse effects
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