Papillon-Lefèvre syndrome. Reappraisal of etiology, clinical features and treatment. II. Oral rehabilitation using osseointegrated implants.

A brief review of aetiological aspects, clinical features and treatment of Papillon-Lefèvre syndrome, is mentioned. A case is reported of a girl having typical features of syndrome. In part II of this article we include oral rehabilitation of these patients using osseointegrated implants.

Neutrophil dysfunction in prepubertal periodontitis associated with Papillon-Lefèvre syndrome.

Although prepubertal periodontitis (PP) is often associated with the Papillon-Lefèvre (PLS), the etiopathogenetic mechanism in this disease has not been clarified as yet. A three and half year old female with leukocyte chemotaxis deficiency and decrease of T-lymphocytes is presented. The immunohistochemical evaluation of neutrophils showed a reduction of myeloperoxidase content, whereas ultrastructural studies revealed no particular change. The possible role of such a deficiency in the pathogenesis of the periodontal lesion is discussed.

Papillon-Lefevre syndrome. A discussion of aetiology and a case report.

A case is reported of a boy with Papillon-Lefevre syndrome. Despite prolonged systemic antibiotic therapy and repeated professional plaque control, the periodontal condition lead to loss of all primary and permanent teeth soon after eruption.

Papillon-Lefèvre syndrome: a case report.

A case of Papillon-Lefèvre syndrome is presented. Hyperkeratosis of the palms and soles along with precocious destruction of the periodontal support of both the primary and permanent dentitions were observed. Ectopic intra-cranial calcified deposits, seen in some cases of the syndrome, were absent in this case. A greater awareness of this condition among dentists and dermatologists would be helpful in identifying more cases for study.

[Extrapalmoplantar skin symptoms and additional clinical, etiological and immunological aspects in particular, in Papillon-Lefevre syndrome]. / Extrapalmoplantare Hautsymptome und weitere klinische und ätiologische, insbesondere immunologische Gesichtspunkte beim Papillon-Lefèvre-Syndrom.

Numerous patients with Papillon-Lefèvre syndrome show scaly erythematous lesions over knees, elbows and the interphalangeal joints additionally to the well known palmo-plantar hyperkeratosis. Not rarely, these skin symptoms are misdiagnosed as psoriasis. The obligatory and highly specific periodontitis marginalis profunda should lead to the correct diagnosis. A basic immune defect, which was shown in such a patient recently, could not be verified in the patient described here.