Asunto(s)
COVID-19/patología , COVID-19/virología , Neuropilina-1/fisiología , Células Ganglionares de la Retina/patología , Células Ganglionares de la Retina/virología , Hemorragia Retiniana/patología , Hemorragia Retiniana/virología , SARS-CoV-2/patogenicidad , Humanos , Factor A de Crecimiento Endotelial Vascular/fisiologíaAsunto(s)
Hemorragia de la Coroides/virología , Infecciones Virales del Ojo/diagnóstico por imagen , Imagen por Resonancia Magnética , Nervio Óptico/diagnóstico por imagen , Hemorragia Retiniana/diagnóstico por imagen , Dengue Grave/diagnóstico por imagen , Enfermedad Aguda , Hemorragia de la Coroides/diagnóstico por imagen , Hemorragia de la Coroides/cirugía , Infecciones Virales del Ojo/cirugía , Infecciones Virales del Ojo/virología , Humanos , Masculino , Nervio Óptico/patología , Hemorragia Retiniana/cirugía , Hemorragia Retiniana/virología , Dengue Grave/cirugía , Dengue Grave/virología , Vitrectomía , Hemorragia Vítrea/diagnóstico por imagen , Hemorragia Vítrea/cirugía , Hemorragia Vítrea/virología , Adulto JovenAsunto(s)
Retinitis por Citomegalovirus/diagnóstico , Linfoma de Células B Grandes Difuso/patología , Neuritis Óptica/diagnóstico , Neuritis Óptica/virología , Papiledema/diagnóstico , Hemorragia Retiniana/diagnóstico , Antivirales/uso terapéutico , Humor Acuoso/virología , Citomegalovirus/genética , Citomegalovirus/aislamiento & purificación , Retinitis por Citomegalovirus/tratamiento farmacológico , Retinitis por Citomegalovirus/virología , Diagnóstico Diferencial , Femenino , Angiografía con Fluoresceína , Foscarnet/uso terapéutico , Humanos , Inyecciones Intravítreas , Persona de Mediana Edad , Neuritis Óptica/tratamiento farmacológico , Papiledema/tratamiento farmacológico , Papiledema/virología , Reacción en Cadena de la Polimerasa , ARN Viral/genética , Hemorragia Retiniana/tratamiento farmacológico , Hemorragia Retiniana/virología , Tomografía de Coherencia ÓpticaAsunto(s)
Retinitis por Citomegalovirus/virología , Oftalmopatías/virología , Seronegatividad para VIH , Hemorragia Retiniana/virología , Vasculitis Retiniana/virología , Cuerpo Vítreo/virología , Administración Oral , Anciano , Antivirales/uso terapéutico , Retinitis por Citomegalovirus/diagnóstico , Retinitis por Citomegalovirus/tratamiento farmacológico , Oftalmopatías/diagnóstico , Oftalmopatías/tratamiento farmacológico , Ganciclovir/análogos & derivados , Ganciclovir/uso terapéutico , Humanos , Infusiones Intravenosas , Inyecciones Intravítreas , Masculino , Hemorragia Retiniana/diagnóstico , Hemorragia Retiniana/tratamiento farmacológico , Vasculitis Retiniana/diagnóstico , Vasculitis Retiniana/tratamiento farmacológico , Valganciclovir , Agudeza Visual , Cuerpo Vítreo/patologíaAsunto(s)
Infecciones por Coxsackievirus/virología , Enterovirus Humano B/aislamiento & purificación , Infecciones Virales del Ojo/virología , Desprendimiento de Retina/virología , Hemorragia Retiniana/virología , Enfermedades Cutáneas Virales/virología , Adulto , Anticuerpos Antivirales/sangre , Ceguera/diagnóstico , Ceguera/fisiopatología , Ceguera/virología , Infecciones por Coxsackievirus/diagnóstico , Infecciones por Coxsackievirus/fisiopatología , Enterovirus Humano B/inmunología , Exudados y Transudados , Infecciones Virales del Ojo/diagnóstico , Infecciones Virales del Ojo/fisiopatología , Humanos , Masculino , Desprendimiento de Retina/diagnóstico , Desprendimiento de Retina/fisiopatología , Hemorragia Retiniana/diagnóstico , Hemorragia Retiniana/fisiopatología , Enfermedades Cutáneas Virales/diagnóstico , Enfermedades Cutáneas Virales/fisiopatología , Tomografía de Coherencia Óptica , Agudeza VisualRESUMEN
Ocular signs and symptoms of Ebola infection initially suggest banal conjunctivitis, but in advanced cases severe haemorrhagic conjunctivitis appears and, in the final stage of the disease, retinal and chorioidal haemorrhages may occur which can cause even blindness. Although the viral infection accompanied by ocular symptoms of a non-specific conjunctivitis, the high fever present from the onset of the disease should raise the suspicion of Ebola infection. There is no causal therapy know so far, and the only adjunctive treatment may be delivered by an ophthalmologist. Because the virus can be detected in the tear, it can theoretically be the mediator of the infection and, therefore, ophthalmological examinations should be carried out with the highest caution. In case of suspected Ebola infection the nearest competent healthcare authority should be immediately alerted in order to take further actions.
Asunto(s)
Oftalmopatías/terapia , Oftalmopatías/virología , Fiebre/virología , Fiebre Hemorrágica Ebola/complicaciones , Fiebre Hemorrágica Ebola/diagnóstico , Conjuntivitis/terapia , Conjuntivitis/virología , Oftalmopatías/diagnóstico , Humanos , Hemorragia Retiniana/terapia , Hemorragia Retiniana/virologíaRESUMEN
PURPOSE: Hand, foot, and mouth disease is a contagious enteroviral infection occurring primarily in children and characterized by vesicular palmoplantar eruptions and erosive stomatitis. There are very few cases of unilateral acute idiopathic maculopathy associated with hand, foot, and mouth infection. We described a case with unilateral outer retinitis occurring a few days after the onset of disease. METHODS: A 30-year-old man with reduced vision in his right eye underwent complete ophthalmologic examination including fluorescein angiography and spectral optical coherence tomography. RESULTS: Fundus fluorescein angiography demonstrated mottled hyperfluorescence in the early phase and leakage in the late phase. Spectral domain optical coherence tomography revealed subretinal fluid suggesting a serous detachment and also showed mild intraretinal cystic changes. The fluid disappeared in 1 week with some retinal pigment epithelium changes in the center of the macula. CONCLUSIONS: Although this disease is a viral infection associated with reversible symptoms, this case suggests that it can resolve with mild visual loss, and the disease should be considered in the differential diagnosis of acute central serous chorioretinopathy.
Asunto(s)
Infecciones Virales del Ojo/diagnóstico , Enfermedad de Boca, Mano y Pie/diagnóstico , Desprendimiento de Retina/diagnóstico , Hemorragia Retiniana/diagnóstico , Enfermedad Aguda , Adulto , Colorantes , Infecciones Virales del Ojo/fisiopatología , Infecciones Virales del Ojo/virología , Angiografía con Fluoresceína , Enfermedad de Boca, Mano y Pie/fisiopatología , Enfermedad de Boca, Mano y Pie/virología , Humanos , Verde de Indocianina , Masculino , Enfermedades Raras , Remisión Espontánea , Desprendimiento de Retina/fisiopatología , Desprendimiento de Retina/virología , Hemorragia Retiniana/fisiopatología , Hemorragia Retiniana/virología , Epitelio Pigmentado de la Retina/patología , Líquido Subretiniano , Tomografía de Coherencia Óptica , Trastornos de la Visión/diagnóstico , Trastornos de la Visión/fisiopatología , Trastornos de la Visión/virología , Agudeza Visual/fisiologíaRESUMEN
A 51-year-old male on chemotherapy for myeloma presented initially with a unilateral optic disc haemorrhage and signs of optic neuropathy. This rapidly progressed to affect both eyes and within a few days he developed retinal features suggestive of progressive outer retinal necrosis. He was treated with intravenous acyclovir that was subsequently changed to ganciclovir when serological tests for cytomegalovirus were found to be positive for immunoglobulin M antibodies. His visual loss continued to deteriorate despite treatment, and he subsequently developed a retinal detachment in one eye. The causes of optic neuropathy in immunocompromised patients and the importance of eliminating an infective cause are discussed.
Asunto(s)
Infecciones por Citomegalovirus/complicaciones , Disco Óptico , Hemorragia Retiniana/virología , Humanos , Masculino , Persona de Mediana EdadRESUMEN
PURPOSE: To describe ocular findings of patients with Crimean-Congo hemorrhagic fever (CCHF). DESIGN: Prospective, interventional, consecutive case series. METHODS: This study was conducted in Sivas, a city located in the central Anatolia, between July 1 and August 31, 2007. Confirmed CCHF patients were enrolled in the study and underwent ocular examination during hospitalization. RESULTS: Nineteen confirmed CCHF patients were included in this study. All patients were classified into 2 groups in terms of disease severity (severe vs nonsevere), according to the Swanepoel predictive criteria. Fourteen patients (73.7%) were classified as "nonsevere," and the remaining 5 patients (26.3%) were classified as "severe" in this study. One patient having severe disease died. Ocular findings were present in 14 patients (73.7%) and none of the patients presented any visual complaints. Ocular examination revealed that 7 patients (36.8%) had only bilateral multiple subconjunctival hemorrhage, and 2 patients (10.5%) (1 bilateral, 1 unilateral) had retinal hemorrhage. Five patients (26.3%) had subconjunctival hemorrhage and retinal hemorrhage. Follow-up examination 1 month later showed complete resorption of the subconjunctival hemorrhage and retinal hemorrhage. There was a statistically significant difference between patients with ocular findings and patients without ocular findings for prothrombin time (P = .011). There was no evidence of uveitis, retinal edema, sheathing of retinal vessels, or intravitreal hemorrhage in our patients. CONCLUSION: From the small sample study, CCHF caused a mild form of ocular disease. CCHF must be considered when subconjunctival or superficial retinal hemorrhages are seen in association with fever in endemic areas.
Asunto(s)
Enfermedades de la Conjuntiva/diagnóstico , Hemorragia del Ojo/diagnóstico , Infecciones Virales del Ojo/diagnóstico , Virus de la Fiebre Hemorrágica de Crimea-Congo/aislamiento & purificación , Fiebre Hemorrágica de Crimea/diagnóstico , Hemorragia Retiniana/diagnóstico , Anticuerpos Antivirales/sangre , Enfermedades de la Conjuntiva/clasificación , Enfermedades de la Conjuntiva/virología , Ensayo de Inmunoadsorción Enzimática , Hemorragia del Ojo/clasificación , Hemorragia del Ojo/virología , Infecciones Virales del Ojo/clasificación , Infecciones Virales del Ojo/virología , Femenino , Virus de la Fiebre Hemorrágica de Crimea-Congo/inmunología , Fiebre Hemorrágica de Crimea/clasificación , Fiebre Hemorrágica de Crimea/virología , Humanos , Inmunoglobulina M/análisis , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Hemorragia Retiniana/clasificación , Hemorragia Retiniana/virologíaAsunto(s)
Infecciones Virales del Ojo/virología , Isquemia/virología , Hemorragia Retiniana/virología , Vasculitis Retiniana/virología , Vasos Retinianos/patología , Fiebre del Nilo Occidental/virología , Adulto , Anciano , Anticuerpos Antivirales/sangre , Anticuerpos Antivirales/líquido cefalorraquídeo , Infecciones Virales del Ojo/diagnóstico , Femenino , Angiografía con Fluoresceína , Humanos , Inmunoglobulina G/sangre , Inmunoglobulina G/líquido cefalorraquídeo , Inmunoglobulina M/sangre , Inmunoglobulina M/líquido cefalorraquídeo , Isquemia/diagnóstico , Masculino , Persona de Mediana Edad , Hemorragia Retiniana/diagnóstico , Vasculitis Retiniana/diagnóstico , Fiebre del Nilo Occidental/diagnóstico , Virus del Nilo Occidental/inmunologíaAsunto(s)
Virus de la Encefalitis Japonesa (Especie) , Encefalitis Japonesa/complicaciones , Mácula Lútea/patología , Hemorragia Retiniana/virología , Encefalitis Japonesa/patología , Femenino , Fondo de Ojo , Humanos , Imagen por Resonancia Magnética , Persona de Mediana Edad , Hemorragia Retiniana/patologíaRESUMEN
We report 4 patients with retinal hemorrhages that developed during hospitalization for dengue fever. Onset of symptoms coincided with resolution of fever and the nadir of thrombocytopenia. Retinal hemorrhages may reflect the rising incidence of dengue in Singapore or may be caused by changes in the predominant serotype of the dengue virus.
Asunto(s)
Dengue/complicaciones , Hemorragia Retiniana/virología , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , SingapurRESUMEN
PURPOSE: To report a case of Dengue fever resulting in permanent visual loss in both eyes due to retinal capillary occlusion. METHODS: Case report. RESULTS: Severe permanent visual loss occurred in a patient with Dengue fever. Dilated fundus exam showed vascular sheathing with associated retinal hemorrhages at the equator and cotton wool spots in the maculae of both eyes. Fluorescein angiography revealed areas of capillary nonperfusion at the equator and in the macula. The diagnosis of Dengue fever was confirmed by serology detecting IgM antibodies to the Dengue virus. CONCLUSION: Ocular abnormalities may be seen in patients with Dengue fever, therefore ophthalmoscopy should be performed in patients presenting with severe forms of the disease.
Asunto(s)
Dengue/diagnóstico , Infecciones Virales del Ojo/diagnóstico , Hemorragia Retiniana/diagnóstico , Vasculitis Retiniana/diagnóstico , Adulto , Anticuerpos Antivirales/sangre , Aspirina/uso terapéutico , Terapia Combinada , Dengue/terapia , Dengue/virología , Virus del Dengue/inmunología , Ensayo de Inmunoadsorción Enzimática , Infecciones Virales del Ojo/terapia , Infecciones Virales del Ojo/virología , Femenino , Angiografía con Fluoresceína , Humanos , Inmunoglobulina M/sangre , Coagulación con Láser , Imagen por Resonancia Magnética , Inhibidores de Agregación Plaquetaria/uso terapéutico , Hemorragia Retiniana/terapia , Hemorragia Retiniana/virología , Vasculitis Retiniana/terapia , Vasculitis Retiniana/virología , Trastornos de la Visión/diagnóstico , Trastornos de la Visión/terapia , Trastornos de la Visión/virología , VitrectomíaAsunto(s)
Dengue/complicaciones , Neuritis Óptica/virología , Hemorragia Retiniana/virología , Viaje , Adulto , Dengue/diagnóstico , Dengue/epidemiología , Enfermedades Endémicas/estadística & datos numéricos , Femenino , Humanos , Neuritis Óptica/diagnóstico , Hemorragia Retiniana/diagnóstico , Tailandia/epidemiología , Agudeza VisualRESUMEN
AIDS ocular complications have been researched in 70 hospitalised patients in the two main hospitals of Bamako (Mali) during one year (1992-1993). Men were predominant (sex ratio 1.6). HIV1 infections (67%) were most frequent than HIV1 + HIV2 (21.4%) or HIV2 infections (11.4%). Most of the patients were on the WHO's clinical stage III; 34% of them had ocular complications, quite often non infectious: cotonous nodules (10%), vascularitis (5.7%) and retineous haemorrhages (4.3%). Ocular opportunistic infections were rare: only one case of toxoplasmic chorio-retinitis was reported. Ocular complications were observed with all types of HIV. Vascular abnormalities were observed in the stage II or IV of AIDS and seemed, in Bamako, as a serious sign during the AIDS course.