ABSTRACT
OBJECTIVE: To evaluate the cytological damage and glutathione peroxidase (GPX) content in the nasal epithelium of residents of Southwest Metropolitan Mexico City (SWMMC) along 1 year of ozone and PM(10) exposure. METHOD: Four nasal scrapings were obtained in 20 volunteers from a control low polluted city and SWMMC permanent residents (n = 20) during 1 year. The scrapings were obtained in September and December 2004, and February and May 2005. One part of the scraping was stained by hematoxylin-eosin technique for cytological evaluation and a second part was stained by immunocytochemistry method to evaluate GPX concentration by morphometry. RESULTS: Control subjects: in total, 30% had no cytological alterations and 70% showed only mild or moderate inflammation in four nasal scrapings. All SWMMC residents showed moderate to severe inflammatory processes in some scrapings. Additionally, dysplasia was found once (in 2 cases) or more than on scraping in five cases (25%). GPX concentration in the control group remained highest in median values throughout the study. SWMMC residents with the highest median values of GPX content were found in the May and September scrapings, and the lowest median values were found in December and February when Ozone and PM(10) levels are increased (P < or = 0.05). A lower GPX content was found as the cytological damage increased (P < or = 0.001). CONCLUSION: Cytological evaluation of nasal epithelium and GPX immunodetection are satisfactory methods to evaluate the earliest damage produced by atmospheric pollution in heavily contaminated cities.
Subject(s)
Air Pollutants/adverse effects , Glutathione Peroxidase/metabolism , Nasal Mucosa/drug effects , Oxidants, Photochemical/adverse effects , Ozone/adverse effects , Particulate Matter/adverse effects , Adult , Cities , Female , Humans , Inflammation/chemically induced , Inflammation/epidemiology , Inflammation/pathology , Male , Mexico/epidemiology , Nasal Mucosa/enzymology , Nasal Mucosa/pathology , Seasons , Urban Health , Urban Population , Young AdultABSTRACT
Since the description of the aesthetic units of the face by González-Ulloa, surgical attempts have been made to achieve excellent results with skin grafts, pedicled flaps, and free flaps. At our institution, we preferentially use microsurgical replacement of the aesthetic units independent of the etiology. The objective of this article is to present a retrospective review of the outcome of patients who underwent these procedures. The etiology, the choice of the procedure, and the functional and aesthetic results are assessed. We suggest the main features according to the results obtained. In this retrospective review, 43 procedures in a 5-year period are analyzed and the results reported. We conclude that the operative procedure is both technically simple and effective over the long term.
Subject(s)
Burns/surgery , Facial Hemiatrophy/surgery , Facial Injuries/surgery , Plastic Surgery Procedures , Adolescent , Adult , Arteriovenous Malformations/surgery , Child , Face/blood supply , Female , Humans , Male , Treatment OutcomeABSTRACT
The temperature elevation resulting from sonically generated heat in rat fetuses was measured for various intensity levels. The temperature elevation produced inside the fetus was higher than that on the outside surface. In live fetuses, a portion of the heat generated was carried off by the circulating blood. The temperature elevation curves were used to estimate the absorption coefficient of rat fetuses. Absorption coefficient values range from 0.065 to 0.086 Np/cm at 1 MHz. The present results are consistent with a theoretical model of temperature elevation in a heated sphere.