ABSTRACT
BACKGROUND: Nonsmall cell lung cancer (NSCLC) has varying epidemiological patterns in different countries and also in different regions of each country. In a country with a high prevalence of lung cancer such as India, regional variations in demography exist. AIM: A study of unique demographic trends of metastatic NSCLC patients presenting to our regional cancer center. MATERIALS AND METHODS: We did a retrospective analysis of histologically confirmed metastatic NSCLC patients who presented to our Department of Medical Oncology between August 2012 and July 2014. RESULTS: A total of 304 patients were analyzed. About 55.6% of the patients were in the age group of 41-60 years. About 79.6% of the patients were symptomatic for <6 months before presentation. About 63.5% of the patients were smokers presenting with a median age of 59 years whereas nonsmokers formed 36.51% of the patients presenting with a median age of 47 (P < 0.001). About 82.6% of the male patients and 4.1% of female patients were smokers. Equal number of all patients had adenocarcinoma (AC) and squamous cell carcinoma (SCC) histology. AC histology was more common in the nonsmoking group (62% of patients). SCC histology was seen in 54.3% of smokers. Metastasis to the contralateral lung and pleura was seen in 58.2% of patients. CONCLUSION: NSCLC presents at a young age. Smoking is a significant risk factor and it is common in the urban populations as in the rural areas. Both AC and SCC histologies presented in equal proportions.
Subject(s)
Adenocarcinoma/epidemiology , Carcinoma, Non-Small-Cell Lung/epidemiology , Carcinoma, Squamous Cell/epidemiology , Adenocarcinoma/pathology , Adult , Aged , Aged, 80 and over , Carcinoma, Non-Small-Cell Lung/pathology , Carcinoma, Squamous Cell/pathology , Female , Humans , India/epidemiology , Male , Middle Aged , Neoplasm Metastasis , Risk Factors , SmokingSubject(s)
Lymphoma, B-Cell/pathology , Tongue Neoplasms/pathology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Combined Modality Therapy , HIV Infections/complications , Humans , Immunohistochemistry , Lymphoma, B-Cell/therapy , Lymphoma, B-Cell/virology , Male , Middle Aged , Radiotherapy , Tongue Neoplasms/therapy , Tongue Neoplasms/virologyABSTRACT
This cytology report highlights a case of rhinosporidiosis of the parotid duct cyst not associated with nasal manifestations. In an endemic area, one should be familiar with its morphologic features in fine-needle aspiration cytology even on scanty material, for it could be one of the investigations in the initial workup of a case.
Subject(s)
Cysts/diagnosis , Nasal Cavity/pathology , Parotid Diseases/diagnosis , Rhinosporidiosis/diagnosis , Cysts/microbiology , Humans , Male , Middle Aged , Nasal Cavity/microbiology , Parotid Diseases/pathology , Rhinosporidiosis/pathology , Tomography, X-Ray ComputedABSTRACT
Neural hypertrophy with hyperplastic Schwann cells in the wall of the stomach along with enterochromaffin cell hyperplasia was incidentally observed at histology in the gastrectomy specimen of a 43-year-old man with carcinoma stomach who had presented with upper abdominal pain of one year duration. The patient had no previous abdominal surgery or evidence of gastrointestinal obstructive pathology. The significance of this neural hypertrophy is not known.
Subject(s)
Carcinoma/pathology , Stomach Neoplasms/pathology , Stomach/innervation , Stomach/pathology , Adult , Biopsy, Needle , Carcinoma/diagnosis , Carcinoma/surgery , Follow-Up Studies , Gastrectomy/methods , Humans , Hypertrophy/pathology , Immunohistochemistry , Male , Myenteric Plexus/pathology , Schwann Cells/pathology , Stomach Neoplasms/diagnosis , Stomach Neoplasms/surgeryABSTRACT
Tumors which are benign in origin in palatine tonsils are not uncommon. They may create anxiety in patients and pose difficulty in differentiating from malignancy. We report a case of tonsillar polyp of lymphangiomatous origin.
