ABSTRACT
The involvement of spa and resort facilities in the system of compulsory health insurance is of primary importance for the improvement of medical aid provided to the population. The application of the methods for the calculation of differential expenditures on the spa and resort-based treatment and estimation of their dependence on a variety of factors may facilitate the more rational use of the available resources of compulsory health insurance.
Subject(s)
Balneology/economics , Health Resorts/economics , National Health Programs/economics , National Health Programs/organization & administration , National Health Programs/standards , Balneology/organization & administration , Costs and Cost Analysis , Humans , RussiaABSTRACT
The inclusion of spa-and-resort facilities in the sphere of compulsory medical insurance is in accordance with the law "On the compulsory medical insurance in the Russian Federation". However, this work implies serious preparatory activity aimed at estimating the requirements of different groups of the country's population in the follow-up treatment and rehabilitation based at the spa-and-resort facilities as well as the available resources for this purpose, modes of payment, rate structure, etc. The spa and resort-based treatment within the framework of the compulsory medical insurance system must be made one of the components of the regional programs of medical rehabilitation.
Subject(s)
Balneology/organization & administration , Balneology/standards , Health Resorts/standards , Insurance, Health/organization & administration , Insurance, Health/standards , Balneology/legislation & jurisprudence , Balneology/trends , Health Resorts/legislation & jurisprudence , Insurance, Health/legislation & jurisprudence , Insurance, Health/trendsSubject(s)
Carbon Tetrachloride Poisoning/drug therapy , Chemical and Drug Induced Liver Injury/drug therapy , Lactulose/therapeutic use , Lipid Peroxidation/drug effects , Animals , Brain/drug effects , Brain/metabolism , Carbon Tetrachloride Poisoning/metabolism , Chemical and Drug Induced Liver Injury/metabolism , Drug Evaluation, Preclinical , Erythrocyte Membrane/drug effects , Erythrocyte Membrane/metabolism , Free Radicals , Lactulose/pharmacology , Liver/drug effects , Liver/metabolism , Male , RatsABSTRACT
The experiments on rats with toxic lesions of the liver induced by tetrachlorinemethane showed that parmidine (pyridinolcarbamat) promotes the reduction of the activity of lipid peroxidation in the liver tissue homogenates and erythrocytes. The pronounced tendency towards normalization of free-radical oxidation correlated with the positive dynamics of the histological picture of the liver.
Subject(s)
Antioxidants/therapeutic use , Carbon Tetrachloride Poisoning/drug therapy , Chemical and Drug Induced Liver Injury/drug therapy , Pyridinolcarbamate/therapeutic use , Animals , Carbon Tetrachloride Poisoning/metabolism , Chemical and Drug Induced Liver Injury/metabolism , Drug Evaluation, Preclinical , Erythrocytes/drug effects , Erythrocytes/metabolism , Lipid Peroxidation/drug effects , Liver/drug effects , Liver/metabolism , Male , Rats , Time FactorsABSTRACT
During the formation and development of atherosclerosis the intensity of lipid peroxidation and the activity of antioxidant defence system significantly change. The use of parmidine decreases the contents of primary and secondary products of lipid peroxidation, reduces peroxide hemolysis of erythrocytes and increases the content of reduced glutathione in erythrocytes of patients with atherosclerosis. This shows that parmidine possessing the antioxidant properties stabilizes lipid peroxidation processes and normalizes the physiological antioxidant system.