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1.
Cureus ; 14(7): e27060, 2022 Jul.
Article in English | MEDLINE | ID: mdl-35891949

ABSTRACT

Pressure ulcer (PU) and burn injury (BI) represent two types of wounds that require broad and difficult fields of treatments. Despite various advances made in recent years, these injuries have few solutions that allow recovery in shorter times and with greater effectiveness. All this negatively affects the patient's quality of life. Since ancient times, with the use of torpedoes (a kind of fish capable of producing electric discharges), it has been believed that the use of electricity could favor the repair processes of various kinds of wounds. Today, technological evolution has allowed the creation of more and more advanced techniques that can determine a better reparative response of the injured tissues. The radio electric asymmetric conveyer (REAC) technology is one of these and the reparative tissue optimization (TO-RPR) treatment represents the specific treatment for these lesions. The two cases presented in this article are intended to highlight how two serious injuries of a different nature, when treated with the REAC TO-RPR, have the same rapid qualitative and quantitative recovery path that continues even after the end of the treatment cycle. The stability and progression of the effects are typical of REAC treatments, and in this article, it is possible to appreciate the clinical evidence. These results together with others previously published open a new therapeutic possibility in the treatment of wounds.

2.
Cureus ; 14(6): e25666, 2022 Jun.
Article in English | MEDLINE | ID: mdl-35677738

ABSTRACT

Breast surgical treatments for both tumors and aesthetic reasons are very frequent. The nipple-areola complex (NAC) ischemia is a possible complication after breast surgery. This lesion can be devastating for the patient in the post-surgical course and can lead to final epidermolysis. The necrosis is generally attributed to vascular compromise or excessive tension of the flaps. Actually, the phenomena that prevent spontaneous repair are due to variations in the endogenous electrical potential at the cellular level. In damaged tissues, the electric potential difference across the epithelium is often profoundly altered. In this manuscript, we are presenting four cases of NAC necrosis that were successfully treated with reparative tissue optimization (TO-RPR) treatment of the Radio Electric Asymmetric Conveyer (REAC) technology. REAC technology was conceived to overcome the limits of exogenous electrical stimulations. Instead of administering an electrical stimulus that imposes itself on the endogenous bioelectric activity (EBA), the REAC technology restores the correct potential difference inside the tissues, which is essential for all reparative and regenerative processes. The REAC treatment applied was able to promote a fast-healing process of the necrosis of the NAC following surgery of the breast.

3.
Cureus ; 14(6): e25768, 2022 Jun.
Article in English | MEDLINE | ID: mdl-35706441

ABSTRACT

Background Fluctuating asymmetry (FA) is widely defined as the deviation from perfect bilateral symmetry and is considered an epigenetic measure of environmental stress. Rinaldi and Fontani hypothesized that the FA morpho-functional changes originate from an adaptive motor behavior determined by functional alterations in the cerebellum and neural circuits, not caused by a lesion, but induced by environmental stress. They called this phenomenon functional dysmetria (FD). On this premise, they developed the radio electric asymmetric conveyer (REAC) technology, a neuromodulation technology aimed at optimizing the best neuro-psycho-motor strategies in relation to environmental interaction. Aims Previous studies showed that specific REAC neuro postural optimization (NPO) treatment can induce stable FD recovery. This study aimed to verify the duration of the NPO effect in inducing the stable FD recovery over time. Materials and methods Data were retrospectively collected from a population of 29,794 subjects who underwent a specific semiological FD assessment and received the NPO treatment, regardless of the pathology referred. Results The analysis of the data collected by the various participants in the study led us to ascertain the disappearance of FD in 100% of the cases treated, with a stability of the result detected up to 18 years after the single administration of the REAC NPO treatment. Conclusions The REAC NPO neurobiological modulation treatment consisting of a single administration surprisingly maintains a very long efficacy in the correction of FD. This effect can be explained as the long-lasting capacity of the NPO treatment to induce greater functional efficiency of the brain dynamics as proven in previous studies.

4.
Psychol Res Behav Manag ; 13: 1247-1256, 2020.
Article in English | MEDLINE | ID: mdl-33376420

ABSTRACT

INTRODUCTION: The purpose of this retrospective study was to compare the effects of two different modalities of administration of the neuro psycho physical optimization (NPPO) neuromodulation treatment, applied with radio electric asymmetric conveyer (REAC) biotechnology devices. Both the modalities are aimed at improving the strategies to deal with and optimize the allostatic response to environmental stressors and exposome. This allows to reduce the dysfunctional adaptive behavior patterns, which underlie many neuropsychological symptoms and pathologies, and to improve the symptoms of depression, anxiety and stress. MATERIALS AND METHODS: From a population of subjects experiencing at least two of the three symptoms depression, anxiety and stress, the selection of pre and post-treatment Depression, Anxiety, Stress 21 items scale (DASS 21) data was made proceeding with a reverse chronological recruitment mechanism, until reaching 150 subjects for each of the 2 groups. The first group was treated with the neuro psycho physical optimization treatment (NPPO), which is the punctiform modality of administration on the auricle pavilion, and the second group was treated with the neuro psycho physical optimization treatment, which is the area modality of administration applied by the planar probe on the cervicobrachial area (NPPO-CB). RESULTS: The Wilcoxon signs test confirmed the differences in scores in pre and post-treatment DASS-21. The comparison between the two groups data and the comparison across groups data showed that NPPO and NPPO-CB have the same efficacy in reducing the symptoms of depression, anxiety and stress, after a single treatment cycle. Statistical significance was set at p <0.05. DISCUSSION: This is the first efficacy descriptive comparison between the two different modalities of administration of the NPPO treatment, as different options for the same clinical indication.

5.
Psychol Res Behav Manag ; 13: 929-937, 2020.
Article in English | MEDLINE | ID: mdl-33204186

ABSTRACT

INTRODUCTION: In addition to the effects of coronavirus infection, the Covid-19 pandemic has induced widespread psychosocial distress, which has triggered the onset of anxious and depressive states, reactive to the socio-relational and economic situation induced by the pandemic. Some of our participants showed depressive and anxious attitudes even in the absence of real pictures of depression and anxiety. This phenomenon, combined with mechanisms of emulation and conditioning, can trigger a vicious cycle within interpersonal relationships and promote the administration of unnecessary treatments. Various approaches have been proposed to help populations suffering from psychosocial problems induced by the Covid-19 pandemic, but there is an objective difficulty in treating a large population. METHODS: To contain and reduce this widespread psychosocial unease, in this study we used two radio electric asymmetric conveyer (REAC) technology neuromodulation treatments, neuro postural optimization (NPO) and neuropsychophysical optimization-cervicobrachial (NPPO-CB), aimed at optimizing an individual's response to the effects of environmental stressors. These treatments are quick and easy to administer; therefore, they can be administered to a large cohort of participants in a short time. To evaluate the effects of the REAC NPO and NPPO-CB treatments, the DASS-21 psychometric test was used because it has already been used to test depression, anxiety, and stress during the Covid-19 pandemic. RESULTS: The results of the study confirm the usefulness of REAC NPO and NPPO-CB treatments in helping participants to have better coping strategies for the environmental pressures and reduce the neuropsychological and behavioral effects induced by the Covid-19 pandemic. DISCUSSION: The results obtained in this study are consistent with previous clinical studies confirming the usefulness of the treatments to face neuropsychological and behavioral effects induced by exposome pressure.

6.
Neuropsychiatr Dis Treat ; 15: 469-480, 2019.
Article in English | MEDLINE | ID: mdl-30858704

ABSTRACT

BACKGROUND: The purpose of this study was to assess the efficacy of specific neuromodulation treatments performed with radio electric asymmetric conveyer (REAC) technology in the treatment of the symptomatic triad depression, anxiety, and stress by the use of a specific psychometric test such as the Depression Anxiety Stress Scale-42 items (DASS-42) version, which assesses simultaneously the severity of expression of this triad. PATIENTS AND METHODS: The design of this study was planned to compare two populations that performed DASS-42 test twice within a similar period of time. The first population performed the first DASS test before the treatment and the second test about 3 months later, at the end of two specific REAC neuromodulation treatments, neuropostural optimization (NPO) and neuropsychophysical optimization (NPPO), that have previously shown an efficacy in the treatment of depression, anxiety and stress. The second population (untreated), used as the randomized control group, consisted of a similar group by gender and age, who performed the DASS-42 test in an online platform twice, with an interval of about 3 months between the first and second tests, similar to the interval between the two tests in the treated group. RESULTS: The comparison between the treated group and the control group points out the REAC treatment efficacy in improving the quality of life. At the second DASS-42 test, self-administered about 3 months after the treatments, treated patients were positioned on average values of much milder severity in all the three clusters, depression, anxiety, and stress, while in untreated patients there was no significant difference between the mean values of the first and second DASS tests. CONCLUSION: The results obtained in this study, evaluated with the DASS-42 test, confirm that REAC-NPO and REAC-NPPO neuromodulation treatments can be useful tools for the clinical treatment of depression, anxiety, and stress, as already proven by previous results evaluated with different psychometric tests.

7.
Neuropsychiatr Dis Treat ; 14: 1047-1054, 2018.
Article in English | MEDLINE | ID: mdl-29713174

ABSTRACT

PURPOSE: The purpose of this preliminary observational study was to evaluate the usefulness of a humanitarian initiative, aimed at improving the neuropsychological and behavioral attitude of children with severe socioeconomic and cultural hardship, in the Brazilian state of Pará. This humanitarian initiative was realized through the administration of two neuromodulation protocols, with radioelectric asymmetric conveyor (REAC) technology. During several years of clinical use, the REAC neuromodulation protocols have already proved to be effective in countering the effects of environmental stress on neuropsycho-physical functions. PATIENTS AND METHODS: After the preliminary medical examination, all subjects were investigated with the Strengths and Difficulties Questionnaire (SDQ), including the impact supplement with teacher's report. After the SDQ, they received the neuromodulation treatment with REAC technology named neuro postural optimization (NPO), to evaluate their responsiveness. Subsequently, every 3 months all subjects underwent a treatment cycle of neuropsycho-physical optimization (NPPO) with REAC technology, for a total of three cycles. At the end of the last REAC-NPPO treatment cycle, all subjects were investigated once again with the SDQ. For the adequacy of the data, the Wilcoxon and the Signs tests were used. For the subdivision into clusters, the Kruskal-Wallis test was applied for the adequacy of the procedure. For all the applied tests, a statistical significance of p<0.5 was found. RESULTS: The results showed that the REAC-NPO and REAC-NPPO neuromodulation protocols are able to improve the quality of life, the scholastic and socialization skills, and the overall state of physical and mental health in children of a family with severe socioeconomic and cultural hardship. CONCLUSION: The REAC-NPO and REAC-NPPO neuromodulation protocols, due to their non-invasive characteristics, painlessness, and speed of administration, can be hypothesized as a treatment to improve the overall state of physical and mental health in a large number of people with socioeconomic and cultural discomfort.

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