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Int J Cardiol ; 130(1): e34-6, 2008 Oct 30.
Article in English | MEDLINE | ID: mdl-17897740

ABSTRACT

Cardiotoxicity is a recognised side effect of intravenous 5-fluorouracils. In the two case reports described we demonstrate similar cardiotoxic side effects seen with the use of capecitabine. With the increasing use of oral adjuvant chemotherapeutic agents, capecitabine should be used with caution in those patients with existing coronary artery disease.


Subject(s)
Angina Pectoris/chemically induced , Antimetabolites, Antineoplastic/adverse effects , Coronary Vasospasm/chemically induced , Deoxycytidine/analogs & derivatives , Fluorouracil/analogs & derivatives , Angina Pectoris/etiology , Capecitabine , Coronary Vasospasm/complications , Deoxycytidine/adverse effects , Fluorouracil/adverse effects , Humans
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