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2.
Geburtshilfe Frauenheilkd ; 35(5): 370-4, 1975 May.
Article in German | MEDLINE | ID: mdl-1150068

ABSTRACT

Estradiol-17beta, estradiol-benzoate, estradiol-valerianate, and estradiol-undecylate were injected intravenously and intramuscularly to postmenopausal woman and to female castrates. Equal doses were used corresponding to 20 mg of free estradiol-17beta. Estradiol-17beta, estrone, FSH and LH were measured in serum by radioimmunoassay before and after application of the hormone and the estradiol esters. Thus the depot effect of the different esters could be compared.


Subject(s)
Estradiol/blood , Estrone/blood , Follicle Stimulating Hormone/blood , Luteinizing Hormone/blood , Adult , Benzoates/pharmacology , Castration , Dose-Response Relationship, Drug , Esters , Estradiol/analogs & derivatives , Female , Humans , Hysterectomy , Infertility, Female/blood , Injections, Intramuscular , Injections, Intravenous , Menopause , Middle Aged , Ovary/surgery , Radioimmunoassay , Structure-Activity Relationship , Undecylenic Acids , Valerates/pharmacology
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