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1.
HIV Med ; 19(2): 123-131, 2018 02.
Article in English | MEDLINE | ID: mdl-29094807

ABSTRACT

OBJECTIVES: The aim of this study was to determine the impact of food insecurity (FI) on HIV viral load and CD4 count among people coinfected with HIV and hepatitis C virus (HCV). METHODS: This study was conducted using data from the Food Security & HIV-HCV Sub-Study of the Canadian Co-Infection Cohort study. FI was measured using the adult scale of Health Canada's Household Food Security Survey Module and was classified into three categories: food security, moderate food insecurity and severe food insecurity. The association between FI, HIV viral load, and CD4 count was assessed using a stabilized inverse probability weighted marginal structural model. RESULTS: A total of 725 HIV/HCV-coinfected people with 1973 person-visits over 3 years of follow-up contributed to this study. At baseline, 23% of participants experienced moderate food insecurity and 34% experienced severe food insecurity. The proportion of people with undetectable HIV viral load was 75% and the median CD4 count was 460 [interquartile range (IQR): 300-665] cells/µL. People experiencing severe food insecurity had 1.47 times [95% confidence interval (CI): 1.14, 1.88] the risk of having detectable HIV viral load and a 0.91-fold (95% CI: 0.84, 0.98) increase in CD4 count compared with people who were food secure. CONCLUSIONS: These findings provide evidence of the negative impact of food insecurity on HIV viral load and CD4 count among HIV/HCV-coinfected people.


Subject(s)
Coinfection/drug therapy , Food Supply , HIV Infections/complications , HIV Infections/drug therapy , Hepatitis C, Chronic/complications , Immune Reconstitution , Sustained Virologic Response , Adult , CD4 Lymphocyte Count , Canada , Cohort Studies , Female , Humans , Male , Middle Aged , Treatment Outcome , Viral Load
2.
J Nutr ; 129(2S Suppl): 525S-528S, 1999 02.
Article in English | MEDLINE | ID: mdl-10064323

ABSTRACT

A conceptual framework showing the household and social implications of food insecurity was elicited from a qualitative and quantitative study of 98 households from a heterogeneous low income population of Quebec city and rural surroundings; the study was designed to increase understanding of the experience of food insecurity in order to contribute to its prevention. According to the respondents' description, the experience of food insecurity is characterized by two categories of manifestations, i.e., the core characteristics of the phenomenon and a related set of actions and reactions by the household. This second category of manifestations is considered here as a first level of consequences of food insecurity. These consequences at the household level often interact with the larger environment to which the household belongs. On a chronic basis, the resulting interactions have certain implications that are tentatively labeled "social implications" in this paper. Their examination suggests that important aspects of human development depend on food security. It also raises questions concerning the nature of socially acceptable practices of food acquisition and food management, and how such acceptability can be assessed. Guidelines to that effect are proposed. Findings underline the relevance and urgency of working toward the realization of the right to food.


Subject(s)
Food Supply , Poverty , Family , Female , Food Services , Health Status , Humans , Hunger , Male , Nutritional Status , Quebec , Rural Population , Social Alienation , Social Values , Stress, Psychological , Surveys and Questionnaires , Urban Population
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