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Alpha-amylase inhibitors from Brazilian seaweeds and their hypoglycemic potential.
Teixeira, Valéria L; Rocha, Fabíola D; Houghton, Peter J; Kaplan, Maria Auxiliadora C; Pereira, Renato C.
Fitoterapia ; 78(1): 35-6, 2007 Jan.
Article in English | MEDLINE | ID: mdl-17067759

ABSTRACT

The acetone crude extract of Lobophora variegata did not show any alpha-amylase inhibition activity. On the contrary, acetone crude extract of both Spatoglossum schroederi and Caulerpa racemosa inhibited the enzyme activity, with an ED(50) of 0.58 and 0.09 mg/ml.


Subject(s)
Enzyme Inhibitors/pharmacology , Hypoglycemic Agents/pharmacology , Phytotherapy , Plant Extracts/pharmacology , Seaweed , alpha-Amylases/adverse effects , Brazil , Enzyme Inhibitors/administration & dosage , Enzyme Inhibitors/therapeutic use , Humans , Hypoglycemic Agents/administration & dosage , Hypoglycemic Agents/therapeutic use , Inhibitory Concentration 50 , Plant Extracts/administration & dosage , Plant Extracts/therapeutic use
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