OBJECTIVE: Our objective was to determine the frequency of rotavirus, adenovirus, and rota-adenovirus co-infections and investigate the fecal leukocyte rate associated with these infections in patients with gastroenteritis. METHODS: This is a retrospective study. We identified patients who were admitted to the pediatric emergency department with acute gastroenteritis and had their stool samples tested for rotavirus and/or adenovirus antigens. Among them, we determined the individuals who underwent stool microscopy tests on the same day and recorded their results. RESULTS: A total of 1,577 patients who underwent testing for rotavirus and/or adenovirus antigens in their stool samples were identified. Among these patients, 583 individuals had concurrent fecal microscopy results. The prevalence of solely rotavirus antigen positivity was 16.4%, solely adenovirus antigen positivity was 2.9%, and rota-adenovirus co-infections were detected in 1.8% of the children. The fecal leukocyte rates in children infected with rotavirus, adenovirus, and rota-adenovirus co-infections were 4.8, 13.3, and 88.9%, respectively. CONCLUSION: The presence of fecal leukocytes was detected at a high rate in cases of viral gastroenteritis, especially in rota-adenovirus co-infections. Therefore, clinicians should not consider only bacterial pathogens in the presence of fecal leukocytes.
Coinfection , Feces , Gastroenteritis , Rotavirus Infections , Humans , Gastroenteritis/virology , Gastroenteritis/epidemiology , Retrospective Studies , Feces/virology , Female , Male , Child, Preschool , Infant , Rotavirus Infections/epidemiology , Acute Disease , Coinfection/epidemiology , Child , Leukocyte Count , Adenovirus Infections, Human/epidemiology , Adenoviridae Infections/epidemiology , Leukocytes , Rotavirus/isolation & purification , Rotavirus/immunology , Adenoviridae/isolation & purification
